YLR270W
(Redirected from DCS1)
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| Systematic name | YLR270W |
| Gene name | DCS1 |
| Aliases | DcpS |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:681186..682238 |
| Primary SGDID | S000004260 |
Description of YLR270W: Non-essential hydrolase involved in mRNA decapping; activates Xrn1p; may function in a feedback mechanism to regulate deadenylation, contains pyrophosphatase activity and a HIT (histidine triad) motif; interacts with neutral trehalase Nth1p; required for growth on glycerol medium[1][2][3]
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References
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- ↑ Liu H, et al. (2002) The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases. EMBO J 21(17):4699-708 SGD PMID 12198172
- ↑ Sinturel F, et al. (2012) Activation of 5'-3' exoribonuclease Xrn1 by cofactor Dcs1 is essential for mitochondrial function in yeast. Proc Natl Acad Sci U S A () SGD PMID 22570495
- ↑ Souza AC, et al. (2002) Evidence for a modulation of neutral trehalase activity by Ca2+ and cAMP signaling pathways in Saccharomyces cerevisiae. Braz J Med Biol Res 35(1):11-6 SGD PMID 11743609
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