YNL111C

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Systematic name YNL111C
Gene name CYB5
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:417302..416940
Primary SGDID S000005055


Description of YNL111C: Cytochrome b5, involved in the sterol and lipid biosynthesis pathways; acts as an electron donor to support sterol C5-6 desaturation[1][2]




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References

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  1. Lamb DC, et al. (1999) Biodiversity of the P450 catalytic cycle: yeast cytochrome b5/NADH cytochrome b5 reductase complex efficiently drives the entire sterol 14-demethylation (CYP51) reaction. FEBS Lett 462(3):283-8 SGD PMID 10622712
  2. Truan G, et al. (1994) Cloning and characterization of a yeast cytochrome b5-encoding gene which suppresses ketoconazole hypersensitivity in a NADPH-P-450 reductase-deficient strain. Gene 142(1):123-7 SGD PMID 8181746

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