YPL177C
(Redirected from CUP9)
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| Systematic name | YPL177C |
| Gene name | CUP9 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:213962..213042 |
| Primary SGDID | S000006098 |
Description of YPL177C: Homeodomain-containing transcriptional repressor of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription[1][2][3]
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References
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- ↑ Byrd C, et al. (1998) The N-end rule pathway controls the import of peptides through degradation of a transcriptional repressor. EMBO J 17(1):269-77 SGD PMID 9427760
- ↑ Knight SA, et al. (1994) Identification and analysis of a Saccharomyces cerevisiae copper homeostasis gene encoding a homeodomain protein. Mol Cell Biol 14(12):7792-804 SGD PMID 7969120
- ↑ Turner GC, et al. (2000) Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway. Nature 405(6786):579-83 SGD PMID 10850718
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