YBR126C
(Redirected from CIF1)
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| Systematic name | YBR126C |
| Gene name | TPS1 |
| Aliases | BYP1, CIF1, FDP1, GGS1, GLC6, TSS1 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:490392..488905 |
| Primary SGDID | S000000330 |
Description of YBR126C: Synthase subunit of trehalose-6-P synthase/phosphatase complex; synthesizes the storage carbohydrate trehalose; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway; protein abundance increases in response to DNA replication stress[1][2][3][4]
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References
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- ↑ Bell W, et al. (1992) Characterization of the 56-kDa subunit of yeast trehalose-6-phosphate synthase and cloning of its gene reveal its identity with the product of CIF1, a regulator of carbon catabolite inactivation. Eur J Biochem 209(3):951-9 SGD PMID 1425702
- ↑ Bell W, et al. (1998) Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex. J Biol Chem 273(50):33311-9 SGD PMID 9837904
- ↑ Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress.LID - 10.1038/ncb2549 [doi] Nat Cell Biol () SGD PMID 22842922
- ↑ Winderickx J, et al. (1996) Regulation of genes encoding subunits of the trehalose synthase complex in Saccharomyces cerevisiae: novel variations of STRE-mediated transcription control? Mol Gen Genet 252(4):470-82 SGD PMID 8879249
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