YNL271C

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Systematic name YNL271C
Gene name BNI1
Aliases PPF3, SHE5
Feature type ORF, Verified
Coordinates Chr XIV:135383..129522
Primary SGDID S000005215


Description of YNL271C: Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNR1[1][2][3][4][5]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [6] [7]





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References

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  1. Chang F and Peter M (2002) Cell biology. Formins set the record straight. Science 297(5581):531-2 SGD PMID 12142518
  2. Dong Y, et al. (2003) Formin-dependent actin assembly is regulated by distinct modes of Rho signaling in yeast. J Cell Biol 161(6):1081-92 SGD PMID 12810699
  3. Lew DJ (2002) Formin' actin filament bundles. Nat Cell Biol 4(2):E29-30 SGD PMID 11835051
  4. Pruyne D, et al. (2002) Role of formins in actin assembly: nucleation and barbed-end association. Science 297(5581):612-5 SGD PMID 12052901
  5. Sagot I, et al. (2002) An actin nucleation mechanism mediated by Bni1 and profilin. Nat Cell Biol 4(8):626-31 SGD PMID 12134165
  6. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  7. submitted by Jeff Ubersax on 2004-01-29

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