YDL100C
(Redirected from ARR4)
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Systematic name | YDL100C |
Gene name | GET3 |
Aliases | ARR4 |
Feature type | ORF, Verified |
Coordinates | Chr IV:283176..282112 |
Primary SGDID | S000002258 |
Description of YDL100C: Guanine nucleotide exchange factor for Gpa1p; amplifies G protein signaling; subunit of the GET complex, which is involved in Golgi to ER trafficking and insertion of proteins into the ER membrane; has low-level ATPase activity[1][2][3][4]
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References
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- ↑ Lee MJ and Dohlman HG (2008) Coactivation of G protein signaling by cell-surface receptors and an intracellular exchange factor. Curr Biol 18(3):211-5 SGD PMID 18261907
- ↑ Schuldiner M, et al. (2005) Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile. Cell 123(3):507-19 SGD PMID 16269340
- ↑ Schuldiner M, et al. (2008) The GET complex mediates insertion of tail-anchored proteins into the ER membrane. Cell 134(4):634-45 SGD PMID 18724936
- ↑ Shen J, et al. (2003) The Saccharomyces cerevisiae Arr4p is involved in metal and heat tolerance. Biometals 16(3):369-78 SGD PMID 12680698
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