YNL223W
(Redirected from APG4)
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| Systematic name | YNL223W |
| Gene name | ATG4 |
| Aliases | APG4, AUT2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:227370..228854 |
| Primary SGDID | S000005167 |
Description of YNL223W: Conserved cysteine protease required for autophagy; cleaves Atg8p to a form required for autophagosome and Cvt vesicle generation[1][2][3]
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References
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- ↑ Kirisako T, et al. (2000) The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J Cell Biol 151(2):263-76 SGD PMID 11038174
- ↑ Meijer WH, et al. (2007) ATG genes involved in non-selective autophagy are conserved from yeast to man, but the selective Cvt and pexophagy pathways also require organism-specific genes. Autophagy 3(2):106-16 SGD PMID 17204848
- ↑ Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 SGD PMID 8224160
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