YPR185W

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Systematic name YPR185W
Gene name ATG13
Aliases APG13
Feature type ORF, Verified
Coordinates Chr XVI:907218..909434
Primary SGDID S000006389


Description of YPR185W: Regulatory subunit of the Atg1p signaling complex; stimulates Atg1p kinase activity; required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; involved in Atg9p, Atg23p, and Atg27p cycling[1][2][3][4]




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References

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  1. Funakoshi T, et al. (1997) Analyses of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae. Gene 192(2):207-13 SGD PMID 9224892
  2. Kabeya Y, et al. (2005) Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy. Mol Biol Cell 16(5):2544-53 SGD PMID 15743910
  3. Reggiori F, et al. (2004) The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure. Dev Cell 6(1):79-90 SGD PMID 14723849
  4. Scott SV, et al. (2000) Apg13p and Vac8p are part of a complex of phosphoproteins that are required for cytoplasm to vacuole targeting. J Biol Chem 275(33):25840-9 SGD PMID 10837477

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