YHR171W

From SGD-Wiki
(Redirected from APG11)
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YHR171W
Gene name ATG7
Aliases APG11, APG7, CVT2
Feature type ORF, Verified
Coordinates Chr VIII:445713..447605
Primary SGDID S000001214


Description of YHR171W: Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes; mediates the conjugation of Atg12p with Atg5p and Atg8p with phosphatidylethanolamine, required steps in autophagosome formation[1][2][3][4]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!






<protect>

References

See Help:References on how to add references

  1. Ichimura Y, et al. (2000) A ubiquitin-like system mediates protein lipidation. Nature 408(6811):488-92 SGD PMID 11100732
  2. Ichimura Y, et al. (2004) In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy. J Biol Chem 279(39):40584-92 SGD PMID 15277523
  3. Mizushima N, et al. (1998) A protein conjugation system essential for autophagy. Nature 395(6700):395-8 SGD PMID 9759731
  4. Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 SGD PMID 8224160

See Help:Categories on how to add the wiki page for this gene to a Category </protect>