YGL180W
(Redirected from APG1)
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| Systematic name | YGL180W |
| Gene name | ATG1 |
| Aliases | APG1, AUT3, CVT10 |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:160065..162758 |
| Primary SGDID | S000003148 |
Description of YGL180W: Protein ser/thr kinase required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for phagophore assembly site formation; during autophagy forms a complex with Atg13p and Atg17p[1][2][3][4][5]
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References
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- ↑ Abeliovich H, et al. (2003) Chemical genetic analysis of Apg1 reveals a non-kinase role in the induction of autophagy. Mol Biol Cell 14(2):477-90 SGD PMID 12589048
- ↑ Cheong H, et al. (2008) The Atg1 Kinase Complex Is Involved in the Regulation of Protein Recruitment to Initiate Sequestering Vesicle Formation for Nonspecific Autophagy in Saccharomyces cerevisiae. Mol Biol Cell 19(2):668-81 SGD PMID 18077553
- ↑ Kabeya Y, et al. (2005) Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy. Mol Biol Cell 16(5):2544-53 SGD PMID 15743910
- ↑ Matsuura A, et al. (1997) Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae. Gene 192(2):245-50 SGD PMID 9224897
- ↑ Straub M, et al. (1997) AUT3, a serine/threonine kinase gene, is essential for autophagocytosis in Saccharomyces cerevisiae. J Bacteriol 179(12):3875-83 SGD PMID 9190802
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