YHR113W

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Systematic name YHR113W
Gene name APE4
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:336337..337809
Primary SGDID S000001155


Description of YHR113W: Cytoplasmic aspartyl aminopeptidase that may also function in the vacuole; CVT pathway cargo protein; cleaves unblocked N-terminal acidic amino acids from peptide substrates; forms a 12-subunit homo-oligomer; M18 metalloprotease family[1][2][3][4][5]




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References

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  1. Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 SGD PMID 16702403
  2. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  3. Kumar A, et al. (2002) Subcellular localization of the yeast proteome. Genes Dev 16(6):707-19 SGD PMID 11914276
  4. Yokoyama R, et al. (2006) Identification of yeast aspartyl aminopeptidase gene by purifying and characterizing its product from yeast cells. FEBS J 273(1):192-8 SGD PMID 16367759
  5. Yuga M, et al. (2011) Aspartyl Aminopeptidase Is Imported from the Cytoplasm to the Vacuole by Selective Autophagy in Saccharomyces cerevisiae. J Biol Chem 286(15):13704-13 SGD PMID 21343297

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