YKL157W

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Systematic name YKL157W
Gene name APE2
Aliases LAP1, YKL158W
Feature type ORF, Verified
Coordinates Chr XI:154991..158232
Primary SGDID S000001640


Description of YKL157W: Aminopeptidase yscII; may have a role in obtaining leucine from dipeptide substrates; APE2 has a paralog, AAP1, that arose from the whole genome duplication[1][2][3][4]




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Protein Details

Protein Localization

Protein identified in a purified mitochondrial extract. [5] [6]





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References

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  1. Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  2. Davis CA, et al. (2000) Test of intron predictions reveals novel splice sites, alternatively spliced mRNAs and new introns in meiotically regulated genes of yeast. Nucleic Acids Res 28(8):1700-6 SGD PMID 10734188
  3. Garcia-Alvarez N, et al. (1991) Molecular cloning of soluble aminopeptidases from Saccharomyces cerevisiae. Sequence analysis of aminopeptidase yscII, a putative zinc-metallopeptidase. Eur J Biochem 202(3):993-1002 SGD PMID 1765107
  4. Hirsch HH, et al. (1988) Aminopeptidase yscII of yeast. Isolation of mutants and their biochemical and genetic analysis. Eur J Biochem 173(3):589-98 SGD PMID 3286257
  5. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  6. submitted by Steffen Ohlmeier on 2004-04-08

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