YLR208W

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Systematic name YLR208W
Gene name SEC13
Aliases ANU3
Feature type ORF, Verified
Coordinates Chr XII:559551..560444
Primary SGDID S000004198


Description of YLR208W: Structural component of three distinct complexes; subunit of the Nup84 nuclear pore sub-complex (NPC), the COPII vesicle coat, and the Seh1-associated (SEA) complex; the COPII vesicle coat is required for vesicle formation in ER to Golgi transport; the Nup84 subcomplex contributes to nucleocytoplasmic transport, NPC biogenesis and processes that may require localization of genes or chromosomes at the nuclear periphery including transcription; homologous to human SEC13[1][2][3][4][5][6][7][8][9][10]




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References

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  1. Antonny B, et al. (2003) Self-assembly of minimal COPII cages. EMBO Rep 4(4):419-24 SGD PMID 12671686
  2. Barlowe C, et al. (1994) COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell 77(6):895-907 SGD PMID 8004676
  3. Copic A, et al. (2012) ER Cargo Properties Specify a Requirement for COPII Coat Rigidity Mediated by Sec13p. Science () SGD PMID 22300850
  4. Dokudovskaya S, et al. (2011) A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae. Mol Cell Proteomics () SGD PMID 21454883
  5. Fernandez-Martinez J and Rout MP (2009) Nuclear pore complex biogenesis. Curr Opin Cell Biol 21(4):603-12 SGD PMID 19524430
  6. Lutzmann M, et al. (2002) Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins. EMBO J 21(3):387-97 SGD PMID 11823431
  7. Menon BB, et al. (2005) Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation. Proc Natl Acad Sci U S A 102(16):5749-54 SGD PMID 15817685
  8. Pryer NK, et al. (1993) Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro. J Cell Biol 120(4):865-75 SGD PMID 8432727
  9. Siniossoglou S, et al. (2000) Structure and assembly of the Nup84p complex. J Cell Biol 149(1):41-54 SGD PMID 10747086
  10. Tous C, et al. (2011) A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors. EMBO J 30(10):1953-64 SGD PMID 21478823

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