YKR021W

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Systematic name YKR021W
Gene name ALY1
Aliases ART6
Feature type ORF, Verified
Coordinates Chr XI:479234..481981
Primary SGDID S000001729


Description of YKR021W: Alpha arrestin that controls nutrient-mediated intracellular sorting of permease Gap1p; interacts with AP-1 subunit Apl4p; may regulate endocytosis of plasma membrane proteins by recruiting ubiquitin ligase Rsp5p to plasma membrane targets[1][2][3]




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References

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  1. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  2. Lin CH, et al. (2008) Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell 135(4):714-25 SGD PMID 18976803
  3. O'Donnell AF, et al. (2010) {alpha}-Arrestins Aly1 and Aly2 Regulate Intracellular Trafficking in Response to Nutrient Signaling. Mol Biol Cell 21(20):3552-66 SGD PMID 20739461

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