YDR063W

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Systematic name YDR063W
Gene name AIM7
Aliases GMF, GMF1
Feature type ORF, Verified
Coordinates Chr IV:578663..579112
Primary SGDID S000002470


Description of YDR063W: Protein that interacts with Arp2/3 complex to stimulate actin filament debranching and inhibit actin nucleation; has similarity to Cof1p and also to human glia maturation factor (GMF); null mutant displays elevated mitochondrial genome loss[1][2][3][4]




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References

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  1. Gandhi M, et al. (2010) GMF is a cofilin homolog that binds Arp2/3 complex to stimulate filament debranching and inhibit actin nucleation. Curr Biol 20(9):861-7 SGD PMID 20362448
  2. Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549
  3. Hess DC, et al. (2009) Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet 5(3):e1000407 SGD PMID 19300474
  4. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095

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