Q0065

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Systematic name Q0065
Gene name AI4
Aliases
Feature type ORF, Verified
Coordinates Mito:13818..21935
Primary SGDID S000007264


Description of Q0065: Endonuclease I-SceII, encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity[1][2]




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References

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  1. Dujardin G, et al. (1982) Single base substitution in an intron of oxidase gene compensates splicing defects of the cytochrome b gene. Nature 298(5875):628-32 SGD PMID 6285204
  2. Wernette CM, et al. (1990) Purification of a site-specific endonuclease, I-Sce II, encoded by intron 4 alpha of the mitochondrial coxI gene of Saccharomyces cerevisiae. J Biol Chem 265(31):18976-82 SGD PMID 2172241

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