[[Category:Newsletter]]
'''About this newsletter:''' 
This is the Winter 2019 issue of the SGD newsletter. The goal of this newsletter is to inform our users about new features in SGD and to foster communication within the yeast community.
__TOC__

==SGD at ICYGMB 2019==
[[Image:ICYGMB.png|link=https://yeast2019.org/ |thumb|right|upright=.7]]
From August 18th-22nd, PI Mike Cherry, Principal Biocuration Scientist Stacia Engel, Senior Biocuration Scientists Barbara Dunn, Edith Wong, and Rob Nash, Biocuration Scientist Suzi Aleksander, Software Developer Felix Gondwe, and Associate Biocuration Scientist Patrick Ng attended the [https://yeast2019.org/ 29th International Conference on Yeast Genetics and Molecular Biology] in Gotheburg, Sweden. Our attending staff presented at a workshop and poster sessions at the meeting, and presentation materials are downloadable at the links below. We had a great time interacting with users and getting their feedback on how to improve SGD as a resource for the budding yeast community.

===Presentations===
{| width="50%" border="1"
|- style="vertical-align:middle;"
| style="text-align:center;"|Presenter
| style="text-align:center;"|Presentation Title
|- style="vertical-align:middle;"
| style="text-align:center;"|Mike Cherry
| style="text-align:center;"|[[:Media:ICYGMB-Sweden-2019-Introduction.pdf | '''"Introduction to SGD Workshop"''']]
|- style="vertical-align:middle;"
| style="text-align:center;"|Stacia Engel
| style="text-align:center;"|[[:Media:ICYGMB2019EngelSGDworkshop.pdf | '''"SGD's Collaboration with the Alliance of Genome Resources"''']]
|- style="vertical-align:middle;"
| style="text-align:center;"|Rob Nash
| style="text-align:center;"|[[:Media:Disease&Abundance_RN_ICYGMB2019_1.pdf | '''"Disease Associations and Protein Abundance"''']]
|- style="vertical-align:middle;"
| style="text-align:center;"|Edith Wong
| style="text-align:center;"|[[:Media:SGD_ICYGMB2019_EDW.pdf | '''"Macromolecular Complexes and Chemical Pages at SGD"''']]
|- style="vertical-align:middle;"
| style="text-align:center;"|Suzi Aleksander
| style="text-align:center;"|[[:Media:GOatSGD YEAST2019.pdf | '''"Gene Ontology at SGD: GO Slim Mapper"''']]
|- style="vertical-align:middle;"
| style="text-align:center;"|Patrick Ng
| style="text-align:center;"|[[:Media:Transcriptome_PN_ICYGMB2019.pdf | '''"Depicting the S288C Transcriptome at SGD"''']]
|- style="vertical-align:middle;"
|-
|}

===Posters===
{| width="50%" border="1"
|- style="vertical-align:middle;"
| style="text-align:center;"|Presenter
| style="text-align:center;"|Poster Title
|- style="vertical-align:middle;"
| style="text-align:center;"|Barbara Dunn
| style="text-align:center;"|[[:Media:ICYGMB-Yeast2019-BeyondS288C_BDv6.pdf | '''"Beyond S288C: Incorporating Genomic Sequence Information from Large-Scale ''S. cerevisiae'' Population Surveys into SGD"''']]
|- style="vertical-align:middle;"
| style="text-align:center;"|Felix Gondwe
| style="text-align:center;"|[[:Media:YGM2018_FG.pdf | '''"Downloading Data from SGD"''']]
|- style="vertical-align:middle;"
| style="text-align:center;"|Edith Wong
| style="text-align:center;"|[[:Media:ISB_poster_2019.pdf | '''"Integration of Macromolecular Complex Data into the ''Saccharomyces'' Genome Database"''']]
|- style="vertical-align:middle;"
| style="text-align:center;"|Patrick Ng
| style="text-align:center;"|[[:Media:ICYGMB_transcripts_variants_poster_2019.pdf | '''"Representing Transcriptional Heterogeneity and Inter-Strain Variation at the ''Saccharomyces'' Genome Database"''']]
|- style="vertical-align:middle;"
| style="text-align:center;"|Stacia Engel
| style="text-align:center;"|[[:Media:SGD&TheAllianceOfGenomeResources081219.pdf | '''"SGD & the Alliance of Genome Resources"''']]
|- style="vertical-align:middle;"
| style="text-align:center;"|Suzi Aleksander
| style="text-align:center;"|[[:Media:YGM2018_SA.pdf | '''"The Use of the Gene Ontology to Describe Biological Function at ''Saccharomyces'' Genome Database"''']]
|- style="vertical-align:middle;"
| style="text-align:center;"|Rob Nash
| style="text-align:center;"|[[:Media:SGD_X_species_comp&disease_associations_08.14.19.pdf | '''"Yeast-Human Cross-Species Complementation and Associations with Disease-related Genes"''']]
|- style="vertical-align:middle;"
|-
|}

==SGD Staff Out and About==
[[Image:CSHLBarbaraJoanna.png|thumb|left|upright=.6|Barbara Dunn and Joanna Argasinska at the SGD booth at Cold Spring Harbor Laboratory. Photo by Constance Brukin.]]
[[Image:CSHLMike.png|thumb|right|upright=.7|Mike Cherry merrily talking yeast biology with colleague Doug Bishop. Photo by Constance Brukin.]]
* On October 7th-11th PI Mike Cherry, Senior Biocuration Scientists Edith Wong and Joanna Argasinska, Biocuration Scientist Suzi Aleksander, and Software Developer Felix Gondwe attended the Gene Ontology Consortium meeting in UC Berkeley, CA.
* On October 23rd-26th, PI Mike Cherry, Senior Biocuration Scientists Barbara Dunn and Joanna Argasinska attended the Yeast Research: Origins, Insights, Breakthroughs meeting in Cold Spring Harbor Laboratory, NY. They presented the poster, [[:Media:SGD_throught_the_years4f.pdf | '''"''Saccharomyces'' Genome Database (SGD) Through the Years"''']] 

==Alliance of Genome Resources at Version 2.3==
[[Image:alliance_logo.png|link=https://www.alliancegenome.org/ |thumb|left|upright=.7]]
The [https://www.alliancegenome.org/ Alliance of Genome Resources], a collaborative effort from SGD and other model organism databases (MOD), released version 2.3 in November. Notable improvements and new features include:
* Disease Pages present individual genetic models and mutants, as well as groupings within Disease Association ribbons.
* Automated Gene Descriptions use an improved algorithm and now include Expression annotations.
* Expression sections on Gene pages link out to external repositories and MOD specific resources.
* Variants with allele/molecular consequences are displayed for Gene/JBrowse pages and downloadable as files.
* Molecular Interactions for individual or all Alliance species are also available as files.

==Updated Metabolic Pathways at SGD==
[[Image:YeastPathways.png|link=https://pathway.yeastgenome.org/ |thumb|right|upright=.8]]
SGD recently updated the [https://www.yeastgenome.org/blog/browse-metabolic-pathways-at-sgd YeastPathways] resource, containing more than 200 biochemical pathways, with help from the [https://biocyc.org/ BioCyc] group at SRI to provide an updated web portal and tools. You can query for metabolic network, pathway, enzyme, or metabolites, as well as access pathways from SGD's Function menu or locus pages for genes with enzymatic roles.

==Sequence Variant Tracks Added to JBrowse==
[[Image:variants.png|link=https://browse.yeastgenome.org/ |thumb|left|upright=.4]]
Sequence tracks that depict single nucleotide polymorphisms and small insertion/deletions mapped relative to the reference strain S288C by [https://www.yeastgenome.org/reference/S000179596 Song ''et al.'' 2015] in 25 S.cerevisiae strains are now viewable in [https://browse.yeastgenome.org/ SGD JBrowse]. They are accessible from the "variants" category when you click the "Select tracks" tab on the upper-left hand of the page. 

==Recent Publications from SGD Staff==
Ng PC, Wong ED, MacPherson KA, Aleksander S, Argasinska J, Dunn B, Nash RS, Skrzypek MS, Gondwe F, Jha S, Karra K, Weng S, Miyasato S, Simison M, Engel SR, Cherry JM (2019) '''Transcriptome visualization and data availability at the ''Saccharomyces'' Genome Database'''. Nucleic Acids Res. 2019 Oct 15. pii: gkz892. doi: 10.1093/nar/gkz892 [https://www.ncbi.nlm.nih.gov/pubmed/31612944 PMID:31612944]

==Happy Holidays from SGD!==
[[File:SnowShmoo.png|thumb|left|upright=.25]]
We want to take this opportunity to wish you and your family, friends and lab mates the best during the upcoming holidays. Stanford University will be closed for two weeks starting on December 24, reopening on January 6th, 2020. Although SGD staff members will be taking time off, the website will be up and running throughout the winter break, and we will attempt to keep connected via email should you have any questions. 

==Upcoming Meetings==
[http://conferences.genetics-gsa.org/tagc/2020/index The Allied Genetics Conference - TAGC 2020] 
Metro Washington, DC 
April 22 to April 26, 2020 

[http://icy15.boku.ac.at 15th International Congress on Yeasts] 
University of Vienna, Vienna, Austria 
August 23 to August 27, 2020 

[http://conferences.genetics-gsa.org/fungal/2019/past-and-upcoming-conferences The 31st Fungal Genetics Conference] 
Asilomar Conference Grounds, Pacific Grove, CA 
March 09 to March 14, 2021

2019-11-21T21:49:50Z

Pcng: Pcng moved page SGD Newsletter, Summer 2019 to SGD Newsletter, Winter 2019

#REDIRECT [[SGD Newsletter, Winter 2019]]

File:CSHLBarbaraJoanna.png

2019-11-21T21:15:07Z

Pcng:

File:CSHLMike.png

2019-11-21T21:14:56Z

Pcng:

SGD Poster Archive

2019-11-21T21:03:01Z

Pcng: /* 2019 */

==2019==
===29th International Conference on Yeast Genetics and Molecular Biology===
'''Swedish Exhibition and Congress Centre (Svenska Mässan)/Hotel Gothia Towers; Gothenburg, Sweden; August 18-22, 2019''' 

*[[Media:ICYGMB-Yeast2019-BeyondS288C_BDv6.pdf | '''Poster''']]: '''"Beyond S288C: Incorporating Genomic Sequence Information from Large-Scale ''S. cerevisiae'' Population Surveys into SGD"'''
*[[Media: Yeast2019_downloads_fgondwe.pdf | '''Poster''']]: '''"Downloading Data from SGD"'''
*[[Media:ISB_poster_2019.pdf | '''Poster''']]: '''"Integration of Macromolecular Complex Data into the ''Saccharomyces'' Genome Database"'''
*[[Media:ICYGMB_transcripts_variants_poster_2019.pdf | '''Poster''']]: '''"Representing Transcriptional Heterogeneity and Inter-Strain Variation at the ''Saccharomyces'' Genome Database"'''
*[[Media:SGD&TheAllianceOfGenomeResources081219.pdf | '''Poster''']]: '''"SGD & the Alliance of Genome Resources"'''
*[[Media:YGM2018_SA.pdf | '''Poster''']]: '''"The Use of the Gene Ontology to Describe Biological Function at ''Saccharomyces'' Genome Database"'''
*[[Media:ICYGMB2019EngelSGDworkshop.pdf | '''Poster''']]: '''"SGD's Collaboration with the Alliance of Genome Resources"'''
*[[Media:SGD_X_species_comp&disease_associations_08.14.19.pdf | '''Poster''']]: '''"Yeast-Human Cross-Species Complementation and Associations with Disease-related Genes"'''
*[[Media:ICYGMB-Sweden-2019-Introduction.pdf | '''Presentation''']]: '''"Introduction to SGD Workshop"'''
*[[Media:ICYGMB2019EngelSGDworkshop.pdf | '''Presentation''']]: '''"SGD's Collaboration with the Alliance of Genome Resources"'''
*[[Media:Disease&Abundance_RN_ICYGMB2019_1.pdf | '''Presentation''']]: '''"Disease Associations and Protein Abundance"'''
*[[Media:SGD_ICYGMB2019_EDW.pdf | '''Presentation''']]: '''"Macromolecular Complexes and Chemical Pages at SGD"'''
*[[Media:GOatSGD YEAST2019.pdf | '''Presentation''']]: '''"Gene Ontology at SGD: GO Slim Mapper"'''
*[[Media:Transcriptome_PN_ICYGMB2019.pdf | '''Presentation''']]: '''"Depicting the S288C Transcriptome at SGD"'''
*[[Media:crossword_yeast2019.pdf | '''Crossword puzzle''']]

===12th International Biocuration Conference===
'''West Road Concert Hall, University of Cambridge; Cambridge, UK; April 7-10, 2019''' 
*[[Media:YGM2018_FG.pdf | '''Poster''']]: '''"Downloading Data from SGD"'''
*[[Media:GO_Biocuration2019.pdf | '''Poster''']]: ''' "In the Know About GO: A Newly Redesigned Website for the Gene Ontology"'''
*[[Media:ISB_poster_2019.pdf | '''Poster''']]: '''"Integration of Macromolecular Complex Data into the ''Saccharomyces'' Genome Database"'''

===30th Fungal Genetics Conference===
'''Asilomar Conference Grounds, Pacific Grove, California; March 12–17, 2019'''
*[[Media:Asilomar_YGM2018_RSN.pdf | '''Poster''']]: '''"Associating Yeast Genes with Human Disease-related Genes at SGD"'''
*[[Media:Biocuration2018_pcng.pdf | '''Poster''']]: ''' "Comparative Genomics at the ''Saccharomyces'' Genome Database"'''

===Yeast research: origins, insights and breakthroughs===
'''Cold Spring Harbor Laboratory, NY; October 23-26, 2019'''
*[[Media:SGD_throught_the_years4f.pdf | '''Poster''']]: '''"Saccharomyces Genome Database (SGD) through the years"'''

==2018==
===Eleventh International Biocuration Conference===
'''Crowne Plaza, Fudan University; Shanghai, China; April 8-11, 2018'''
[[File:ISB_2016_logo.png|thumb|left|upright=.5| [http://biocuration2018.cn/biocuration2018/ Meeting website]]]
 
*[[Media:Biocuration2018_pcng.pdf | '''Poster''']]: '''"Comparative Genomics at the ''Saccharomyces'' Genome Database"'''
*[[Media:Regulation2018poster.pdf | '''Poster''']]: '''"Updated regulation curation model at the ''Saccharomyces'' Genome Database"'''
*[[Media:Biocuration_2018_Expression_EW.pdf | '''Presentation''']]: '''"Gene and Protein Expression Data at the ''Saccharomyces'' Genome Database"'''
*[[Media:Biocuration_2018_Regulation_SE.pdf | '''Presentation''']]: '''"Updated regulation curation model at the ''Saccharomyces'' Genome Database"'''
 

==2017==
===Yeast Genetics and Genomics===
'''CSHL; Cold Spring Harbor, NY; July 25 - August 14, 2017'''
[[File:CSHL_Logo.gif|thumb|left|upright=.5| [http://meetings.cshl.edu/courses.aspx?course=c-yeas&year=17 Course Website]]]
 
*[[Media:2017_CSHL_yeast_course_data_analysis.pdf | '''Presentation''']]: '''"Data analysis: YeastMine, GO tools, and use cases"'''
 

===Tenth International Biocuration Conference===
'''Li Ka Shing Learning and Knowledge Center; Stanford, CA; March 26-29, 2017'''
[[File:ISB_2016_logo.png|thumb|left|upright=.5| [http://med.stanford.edu/biocuration.html Meeting website]]]
 
*[[Media:Biocuration_2017_Protein.pptx | '''Presentation (pptx)''']]: '''"Curated Protein Information in the ''Saccharomyces'' Genome Database"'''
*[[Media:Biocuration_2017_Outreach.pdf | '''Presentation''']]: '''"Outreach and Online Training Services"'''
 

===Fungal Genetics Meeting===
'''Asilomar Conference Center; Pacific Grove, CA; March 14-19, 2017'''
[[File:fungalgenetics2015.png|thumb|left|upright=0.5| [http://www.genetics-gsa.org/fungal/2017/ Meeting website]]]

*[[Media:TAGC_variantviewer_poster.pdf | '''Poster''']]: "'''The ''Saccharomyces'' Genome Database Variant Viewer'''"
*[[Media:TAGC_outreach_poster.pdf | '''Poster''']]: "'''''Saccharomyces'' Genome Database: Outreach and online training services'''"
 

==2016==
===Yeast Genetics and Genomics===
'''CSHL; Cold Spring Harbor, NY; July 26 - August 15, 2016'''
 
[[File:CSHL_Logo.gif|thumb|left|upright=.5| [http://meetings.cshl.edu/courses.aspx?course=c-yeas&year=16 Course Website]]]

*[[Media:CSHL_yeast_course_2016_SGD_tour.pptx | '''Presentation (pptx)''']]: '''"A hands on tour of the ''Saccharomyces'' Genome Database (SGD)"'''
*[[Media:CSHL_yeast_course_2016_data_analysis.pptx | '''Presentation (pptx)''']]: '''"Data Analysis: GO tools, YeastMine, and use-case examples"'''
 

===The Allied Genetics Conference===
'''Orlando World Center Marriott; Orlando, Florida; July 13-17, 2016'''
[[File:TAGC_Logo_2016.png|thumb|left|upright=.5| [http://www.genetics2016.org '''Meeting website''']]]
 
*[[Media:TAGC-FindingDataPoster.pdf | '''Poster''']]: "'''''Saccharomyces'' Genome Database: How to find what you are looking for'''"
*[[Media:TAGC_variantviewer_poster.pdf | '''Poster''']]: "'''The ''Saccharomyces'' Genome Database Variant Viewer'''"
*[[Media:TAGC-PTM-poster.pdf | '''Poster''']]: "'''Post-Translational Modification Data in the ''Saccharomyces'' Genome Database'''"
*[[Media:Biocuration2015posterBig.pdf | '''Poster''']]: "'''Homology Curation at SGD: budding yeast as a model for eukaryotic biology'''"
*[[Media:TAGC_outreach_poster.pdf | '''Poster''']]: "'''''Saccharomyces'' Genome Database: Outreach and online training services'''"
 

===Ninth International Biocuration Conference===
Campus Biotech Geneva; Geneva, Switzerland; April 10-14, 2016
[[File:ISB_2016_logo.png|thumb|left|upright=.5| [https://www.isb-sib.ch/events/biocuration2016/home Meeting website]]]
 
*[[Media:BiocurationTalk2016.pptx | Presentation (pptx)]]: "From one to many: expanding the ''Saccharomyces cerevisiae'' reference genome panel"

 

==2015==
===27th International Conference on Yeast Genetics and Molecular Biology===
PalaLevico Valsugana Fiere; Levico Terme, Italy; September 6-12, 2015
[[File:ICYGMB_Logo_1.png|thumb|left|upright=.5| [http://yeast2015.eu Meeting website]]]

*[[Media:Yeast2015_EW_v4.pdf | Poster]]: "Integrating genome-wide datasets into the ''Saccharomyces'' Genome Database"
*[[Media:Giltae_Poster_Yeast2015.pdf | Poster]]: "Inferring genome variation patterns in ''Saccharomyces cerevisiae'' using the eukaryote pan-genome toolset "
*[[Media:Biocuration2015posterBig.pdf | Poster]]: "Homology Curation at SGD: budding yeast as a model for eukaryotic biology"
 
===Yeast Genetics and Genomics===
CSHL; Cold Spring Harbor, NY; July 21 - August 10, 2015
[[File:CSHL_Logo.gif|thumb|left|upright=.5| [http://meetings.cshl.edu/courses.aspx?course=c-yeas&year=15 Course Website]]]

*[[Media:SGD_CSHL_2015_Site_Tour.pptx | Presentation (pptx)]]: "Navigating data at the ''Saccharomyces'' Genome Database"
*[[Media:SGD_CSHL_2015_Analysis.pptx | Presentation (pptx)]]: "Data Analysis: GO tools and YeastMine, use-case examples"
 

===Fungal Genetics Meeting===
Asilomar Conference Center; Pacific Grove, CA; March 17-22, 2015
[[File:fungalgenetics2015.png|thumb|left|upright=0.5| [http://www.genetics-gsa.org/fungal/2015/ Meeting website]]]

*[[Media:SGD_overview_fungal_genetics.pptx | Presentation (pptx)]]: "The power of SGD"
 

===Eighth International Biocuration Conference===
Beijing Friendship Hotel; Beijing, China; April 23-26, 2015
[[File:Biocurator_logo.gif|thumb|left|upright=0.5| [http://biocuration2015.big.ac.cn Meeting website]]]

*[[Media:Biocuration2015posterBig.pdf | Poster]]: "Homology Curation at SGD: budding yeast as a model for eukaryotic biology"

*[[Media:StaciaEngelWorkshop5.pptx | Presentation (pptx)]]: "Homology Curation at SGD: budding yeast as a model for eukaryotic biology"

*[[Media:biocuration2015_Rama.pdf | Poster]]: "Collection and curation of whole genome studies of budding yeast at the ''Saccharomyces'' Genome Database"

*[[Media:RamaCollaborationBeijing2015.pptx | Presentation (pptx)]]: "Collaboration with IntAct and InterMine: SGD"

*[[Media:DataVisualizationChina2015RamaMoni.pdf | Presentation (pdf)]]: "Data Visualization & Annotation"
 

==2014==
===Gene Ontology Consortium Meeting===
Texas A&M; College Station, TX; March 16-17, 2014
[[File:GO_Logo.png|thumb|left|upright=0.5]]

*[[Media:Rama-GAPD-GPI-ISB2.pdf | Poster]]: "GPAD/GPI: Next generation file format for GO annotations"

*[[Media:CherryLabGOC.pptx | Presentation (pptx)]]: "State of the GOC"

===Systems Biology: Global Regulation of Gene Expression===
CSHL; Cold Spring Harbor, NY; March 18-22, 2014
[[File:CSHL_Logo.gif|thumb|left|upright=.5| [http://meetings.cshl.edu/meetings/2014/systems14.shtml Meeting Website]]]

*[[Media:cshl_sb_2014.pdf | Poster]]: "Defining the transcriptome of ''Saccharomyces cerevisiae''"

===Seventh International Biocuration Conference (ISB2014)===
The University of Toronto; Toronto, Canada; April 6-9, 2014
[[File:Biocurator_logo.gif|thumb|left|upright=0.5| [http://biocuration2014.events.oicr.on.ca/biocuration Meeting website]]]

*[[Media:Biocurator2014posterSRE.pdf | Poster]]: "Staying current and modern: Overhauling an actively-used organism database website"
*[[Media:Costanzo_Biocuration_2014.pdf | Poster]]: "''Saccharomyces'' Genome Database Integrates Transcriptional Regulation Data"
*[[Media:SD_posterv2_Biocuration_2014.pdf | Poster]]: "Yeast--why it simply has a lot to say about human disease"
*[[Media:biocuration_talk_final.pptx | Presentation (pptx)]]: "Yeast--why it simply has a lot to say about human disease"

===22nd Annual International Conference on Intelligent Systems for Molecular Biology (ISMB2014)===
Hynes Convention Center; Boston, MA; July 11-15, 2014
[[File:ismb2014logo.png|thumb|left|upright=0.5| [http://www.iscb.org/ismb2014 Meeting Website]]]

*[[Media:ISMB_2014-EDW.pdf | Poster]]: "Integrating multiple data types toward functional annotation of ''Saccharomyces cerevisiae''"

===Yeast Genetics Meeting===
University of Washington; Seattle, WA; July 29 - August 3, 2014
[[File:Yeast_Genetics_Logo.png|thumb|left|upright=.65| [http://www.genetics-gsa.org/yeast/2014/ Meeting Website]]]

*[[Media:YGM2014posterSRE.pdf | Poster]]: "Transcriptional regulation and protein complexes in budding yeast"

 
 
 
 

==2013==
===Sixth International Biocuration Conference===
Churchill College; Cambridge, UK; April 7-10
[[File:Biocurator_logo.gif|thumb|left|upright=0.5|[http://www.ebi.ac.uk/biocuration2013/ Meeting Website]]]

*[[Media:Biocurator2013posterSRE.pdf | Poster]]: "New modern era of yeast genomics: annotation of multiple ''Saccharomyces cerevisiae'' strains at SGD"

*[[Media:Costanzo_Biocuration2013.pdf | Poster]]: "New Regulation Data in the ''Saccharomyces'' Genome Database"

===26th International Conference on Yeast Genetics and Molecular Biology===
Frankfurt University; Frankfurt, Germany; August 29 - September 3, 2013
[[File:2013_YeastGenetics_Frankfurt.png|thumb|left|[http://www.yeast-2013.org/faces/index Meeting Website]]]

*[[Media:Stacia_EngelYGM2013.pdf | Presentation]]: "The modern era of yeast genomics: Annotation of multiple ''Saccharomyces cerevisiae'' strains at SGD"

===Cell Biology of Yeasts===
CSHL; Cold Spring Harbor, NY; November 5-9, 2013
[[File:CSHL_Logo.gif|thumb|left|upright=.5| [http://meetings.cshl.edu/meetings/2013/yeast13.shtml Meeting Website]]]

*[[Media:Costanzo_Retreat_CSH_2013.pdf | Poster]]: "New Regulation Data in the ''Saccharomyces'' Genome Database"

 

==2012==
===Fifth International Biocuration Conference===
Georgetown University; Washington DC; April 2-4, 2012
[[File:Biocurator_logo.gif|thumb|left|upright=0.5|[http://pir.georgetown.edu/biocuration2012/ Meeting Website]]]

*[[Media:Biocurator2012.park.pdf | Presentation]]: CvManGo

SGD Poster Archive

2019-11-21T21:02:14Z

2019-10-02T23:42:03Z

Pcng:

This page lists all sequence and annotation changes that have been made to the Chromosome I systematic reference sequence since its intial release on 1996-07-31.
*The sequence of Chromosome I has been updated '''115''' times, affecting '''55''' features. 
*The annotation of Chromosome I has been updated '''25''' times, affecting '''39''' features. 
Current and past versions can be obtained from SGD's [https://www.yeastgenome.org/downloads Download site].

__FORCETOC__

=Sequence Changes=

{| border="1" style="border-collapse:collapse; width:90%" cellpadding="6"
! Date !! Affected Features !! Start Coordinate of Change !! End Coordinate of Change !! Type of Change !! Old Sequence !! New Sequence
|-
| 2011-02-03
| [https://www.yeastgenome.org/locus/YAL013W YAL013W]
| 130485
| 130486
| Deletion
| GT
|
|-
| || colspan="6" |Two nucleotides were deleted near the 3' end of ORF DEP1/[https://www.yeastgenome.org/locus/YAL013W YAL013W], altering its coding sequence. The start and most of the reading frame remain the same, but the C-terminus has changed and the annotated protein is now 15 amino acids shorter.
<pre>New 130445 AGACTCCGAAATCAACGACGACTTCCACCAGTGGGCCCA--GTGACCGCCACACTGGACC 130502
||||||||||||||||||||||||||||||||||||||| |||||||||||||||||||
Old 130446 AGACTCCGAAATCAACGACGACTTCCACCAGTGGGCCCAGTGTGACCGCCACACTGGACC 130505</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YAR019W-A YAR019W-A]
| 175305
| 175305
| Insertion
|
| C
|-
| || colspan="6" |A single C nucleotide was inserted very near the 3' end of ORF [https://www.yeastgenome.org/locus/YAR019W-A YAR019W-A], altering its coding sequence. The start and most of the reading frame remain the same, but the C-terminus has changed and the annotated protein is now 4 amino acids shorter.
<pre>New 175295 GGCACAGCAAAGTCCGCACAGAGCACTACAGTATAGCATAGAGTGCTAATGAGTTGATAG 175354
||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||
Old 175293 GGCACAGCAAAGT-CGCACAGAGCACTACAGTATAGCATAGAGTGCTAATGAGTTGATAG 175351</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YAL064W YAL064W]
| 21531
| 21531
| Insertion
|
| A
|-
| || colspan="6" |A single A nucleotide was inserted within ORF [https://www.yeastgenome.org/locus/YAL064W YAL064W], near its 5' end, moving the start codon out of frame with the rest of the protein. The C-terminus and majority of the reading frame remain the same, but the N-terminus has changed and the annotated protein is now 14 amino acids shorter.
<pre>New 21487 CTATCGATGTGTATACAAACGTACTTCAAATAAGCAATGCGAATATACTGCAACTTTTCG 21546
|||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 21490 CTATCGATGTGTATACAAACGTACTTCAAATAAGCAATGCGA-TATACTGCAACTTTTCG 21548</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="9"| 2011-02-03
| rowspan="9"| [https://www.yeastgenome.org/locus/YAR014C YAR014C]
| 167048
| 167048
| Substitution
| G
| C
|-style="height:30px; width:30px; text-align:center;"
| 167084
| 167084
| Insertion
|
| C
|-style="height:30px; width:30px; text-align:center;"
| 167113
| 167113
| Insertion
|
| T
|-style="height:30px; width:30px; text-align:center;"
| 167133
| 167133
| Insertion
|
| A
|-style="height:30px; width:30px; text-align:center;"
| 167138
| 167138
| Insertion
|
| T
|-style="height:30px; width:30px; text-align:center;"
| 167142
| 167142
| Insertion
|
| A
|-style="height:30px; width:30px; text-align:center;"
| 167149
| 167149
| Insertion
|
| T
|-style="height:30px; width:30px; text-align:center;"
| 167551
| 167551
| Substitution
| G
| C
|-style="height:30px; width:30px; text-align:center;"
| 167802
| 167802
| Substitution
| C
| T
|-
| || colspan="6" |Six separate single nucleotides were inserted within ORF BUD14/[https://www.yeastgenome.org/locus/YAR014C YAR014C], and three single nucleotide substitutions were also made, altering its coding sequence. The start, stop, and majority of the reading frame remain the same, but the annotated protein is now two amino acids longer and a small section of the protein sequence is now different.
<pre>New 167033 GTCAGTTTGATTTGCCATTCCTCCACTAGACCCCAAGCTGGCTTGAATTTGCCCCTCTGT 167092
|||||||||||||| |||||||||||||||||||||||||||||||||||| ||||||||
Old 167034 GTCAGTTTGATTTGGCATTCCTCCACTAGACCCCAAGCTGGCTTGAATTTG-CCCTCTGT 167092

New 167093 GTTTTCCACGTTTGTTGTCTCTTCAATTTTCGATTTTGCATGAATATATTGTGAAATGTC 167152
||||||||||||||||||||| |||||||||||||||||||| ||||| |||| ||||||
Old 167093 GTTTTCCACGTTTGTTGTCTC-TCAATTTTCGATTTTGCATG-ATATA-TGTG-AATGTC 167148

New 167153 CTTTATTGCTCTAGATGATGGAATACTGCTGCTTTCTTCAACTATTGGAGTGGATGGTGA 167212
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Old 167149 C-TTATTGCTCTAGATGATGGAATACTGCTGCTTTCTTCAACTATTGGAGTGGATGGTGA 167207

New 167513 GACGTCGCTCACTACATCGCTCGTATCATCATCCTGGAATTTGCCAAAATTTAACTTCGC 167572
||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||
Old 167508 GACGTCGCTCACTACATCGCTCGTATCATCATCCTGGAATTTGGCAAAATTTAACTTCGC 167567

New 167763 TATCCATTCAGTGCAGGTGTCGGAATTATACTCTCTGCATCACTTTGATTCTTGTTACCA 167822
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 167758 TATCCATTCAGTGCAGGTGTCGGAATTATACTCTCTGCATCACTCTGATTCTTGTTACCA 167817</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YAL051W YAL051W]
| 48772
| 48772
| Substitution
| T
| A
|-style="height:30px; width:30px; text-align:center;"
| 49904
| 49904
| Substitution
| C
| A
|-style="height:30px; width:30px; text-align:center;"
| 50327
| 50327
| Substitution
| C
| A
|-
| || colspan="6" |Nucleotide changes within the coding region of OAF1/[https://www.yeastgenome.org/locus/YAL051W YAL051W] resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 70 is now Arginine rather than Tryptophan, residue 447 is now Glutamine rather than Proline, and residue 588 is now Lysine rather than Threonine.
<pre>New 48726 CATAATAGGAAAAGAAATAGAATATTGTTTGTCTGCCAGGCTTGTAGGAAGTCAAAAACA 48785
||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||
Old 48727 CATAATAGGAAAAGAAATAGAATATTGTTTGTCTGCCAGGCTTGTTGGAAGTCAAAAACA 48786

New 49856 AATAATTGATAAATACCCAATACCGAACGATTTTATTTTATTGAGTCAAAGATGTCTAGC 49915
||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
Old 49857 AATAATTGATAAATACCCAATACCGAACGATTTTATTTTATTGAGTCCAAGATGTCTAGC 49916

New 50286 AACCGAGTTAGGGGCGATCTAAGCGATATCAATAATCACAAACTTTTGAGAATTCATAAA 50345
|||||||||||||||||||||||||||||||||||||||| |||||||||||||||||||
Old 50287 AACCGAGTTAGGGGCGATCTAAGCGATATCAATAATCACACACTTTTGAGAATTCATAAA 50346</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="4"| 2011-02-03
| rowspan="4"| [https://www.yeastgenome.org/locus/YAL053W YAL053W]
| 46231
| 46231
| Substitution
| C
| G
|-style="height:30px; width:30px; text-align:center;"
| 46833
| 46833
| Substitution
| G
| A
|-style="height:30px; width:30px; text-align:center;"
| 47821
| 47821
| Substitution
| T
| A
|-style="height:30px; width:30px; text-align:center;"
| 47826
| 47826
| Substitution
| C
| T
|-
| || colspan="6" |Nucleotide changes within the coding region of FLC2/[https://www.yeastgenome.org/locus/YAL053W YAL053W] resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 111 is now Cysteine rather than Serine, residue 312 is now Asparagine rather than Aspartic Acid, and residues 641-643 are now NDS rather than IDP.
<pre>New 46196 TTTGATTTATGTTCCTTGGGCCAAGTATCGCTTTGCCCCCTAAGTGCTGGGCGTATTGAT 46255
|||||||||||||||||||||||||||||||||| |||||||||||||||||||||||||
Old 46197 TTTGATTTATGTTCCTTGGGCCAAGTATCGCTTTCCCCCCTAAGTGCTGGGCGTATTGAT 46256

New 46796 AGTGATTACAATTTTGACACCATTTTAGACGATTCGAATCTGTACACCACTTCTGAGAAG 46855
|||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
Old 46797 AGTGATTACAATTTTGACACCATTTTAGACGATTCGGATCTGTACACCACTTCTGAGAAG 46856

New 47806 TGGCAAAAACAAAAATGATTCTGAACTGTTTGAATTGAGAAAAGCTGTTATGGACACCAA 47865
|||||||||||||| |||| ||||||||||||||||||||||||||||||||||||||||
Old 47807 TGGCAAAAACAAAATTGATCCTGAACTGTTTGAATTGAGAAAAGCTGTTATGGACACCAA 47866</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YAR023C YAR023C]
| 179683
| 179683
| Substitution
| T
| A
|-style="height:30px; width:30px; text-align:center;"
| 179761
| 179761
| Substitution
| C
| A
|-
| || colspan="6" |The substitution of two nucleotides within the coding region of [https://www.yeastgenome.org/locus/YAR023C YAR023C] resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 20 is now Phenylalanine rather than Valine, and residue 46 is now Phenylalanine rather than Isoleucine.
<pre>New 179672 ATTGGTCTACTGAATGACCATATCTGAAGGACTACCATAGAGCCACCTAAACATATCCGG 179731
||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||
Old 179670 ATTGGTCTACTGATTGACCATATCTGAAGGACTACCATAGAGCCACCTAAACATATCCGG 179729

New 179732 ATCACCATGGCAGGGGAGAGAACACCAGAAAACCAAATGTTTGTTAAAGTCGCCAAAATC 179791
||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||||
Old 179730 ATCACCATGGCAGGGGAGAGAACACCAGAAACCCAAATGTTTGTTAAAGTCGCCAAAATC 179789</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="7"| 2011-02-03
| rowspan="7"| [https://www.yeastgenome.org/locus/YAL026C YAL026C]
| 96838
| 96838
| Deletion
| C
|
|-style="height:30px; width:30px; text-align:center;"
| 98350
| 98351
| Substitution
| CG
| GC
|-style="height:30px; width:30px; text-align:center;"
| 97678
| 97679
| Substitution
| CC
| GG
|-style="height:30px; width:30px; text-align:center;"
| 97025
| 97026
| Substitution
| AT
| TA
|-style="height:30px; width:30px; text-align:center;"
| 99563
| 99565
| Substitution
| ATC
| TCG
|-style="height:30px; width:30px; text-align:center;"
| 96740
| 96740
| Substitution
| G
| C
|-style="height:30px; width:30px; text-align:center;"
| 96841
| 96841
| Insertion
|
| C
|-
| || colspan="6" |Nucleotide changes within the coding region of DRS2/[https://www.yeastgenome.org/locus/YAL026C YAL026C] resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 45-46 are now AN rather than GY, residue 450 is now Alanine rather than Arginine, residue 674 is now Proline rather than Glycine, residues 891-892 are now NT rather than KS, residues 953-954 are now GD rather than AS, and residue 987 is now Valine rather than Leucine.
<pre>New 96716 TTTTAAAAATTTAAATTGGCCAACAGCTATATCAGCTGAACGAGCCGCTTGCATACCTTC 96775
||||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||
Old 96717 TTTTAAAAATTTAAATTGGCCAAGAGCTATATCAGCTGAACGAGCCGCTTGCATACCTTC 96776

New 96826 CGTTGGCACCA-TCGCCAATGGCTAGCAGTAGTGAAGACGACTTTCTTTTTACCATTTTA 96884
||||||||||| ||| ||||||||||||||||||||||||||||||||||||||||||||
Old 96827 CGTTGGCACCACTCG-CAATGGCTAGCAGTAGTGAAGACGACTTTCTTTTTACCATTTTA 96885

New 97005 TCAATGACGAGCGCTAAGGTATTCATATCATGTGTTGACAATTGATGCTCGTTTAGAGCG 97064
||||||||||||||||||| |||||||||||||||||||||||||||||||||||||||
Old 97006 TCAATGACGAGCGCTAAGGATTTCATATCATGTGTTGACAATTGATGCTCGTTTAGAGCG 97065

New 97665 GTTACAGAGTTTGGTTTACGGATGATAAACTTATACCCTAAATCTGCACCACCTTGAACG 97724
|||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||
Old 97666 GTTACAGAGTTTCCTTTACGGATGATAAACTTATACCCTAAATCTGCACCACCTTGAACG 97725

New 98335 AAACTGTGAACAATGCAATAATCTGTCTGTTGATAATTTTCTCAACCGCGGTTCTTTTAA 98394
|||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Old 98336 AAACTGTGAACAATCGAATAATCTGTCTGTTGATAATTTTCTCAACCGCGGTTCTTTTAA 98395

New 99535 GAAGTACATGACTTGGTGGTATATAATTCGCGTTCGCATGTGAGTTGGTGACCTTTGAAC 99594
||||||||||||||||||||||||||| ||||||||||||||||||||||||||||||
Old 99536 GAAGTACATGACTTGGTGGTATATAATATCCGTTCGCATGTGAGTTGGTGACCTTTGAAC 99595</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="4"| 2011-02-03
| rowspan="4"| [https://www.yeastgenome.org/locus/YAR019C YAR019C]
| 172425
| 172425
| Insertion
|
| G
|-style="height:30px; width:30px; text-align:center;"
| 174173
| 174173
| Substitution
| G
| C
|-style="height:30px; width:30px; text-align:center;"
| 174187
| 174188
| Substitution
| CG
| GC
|-style="height:30px; width:30px; text-align:center;"
| 172434
| 172434
| Deletion
| G
|
|-
| || colspan="6" |Nucleotide changes within the coding region of CDC15/[https://www.yeastgenome.org/locus/YAR019C YAR019C] resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 316 is now Alanine rather than Arginine, residue 321 is now Alanine rather than Proline, and 900-902 are now KDV rather than NGC.
<pre>New 172416 GAATTCCTTTTTGGGACATCC-TTGTTCCAGTTGTTGTTTAAAAACTCCGTTATTTGTAC 172474
|||||||||||| |||||||| ||||||||||||||||||||||||||||||||||||||
Old 172414 GAATTCCTTTTT-GGACATCCGTTGTTCCAGTTGTTGTTTAAAAACTCCGTTATTTGTAC 172472

New 174165 TCTGCCCAGGCAGCGGGAGCCGCTGCAAGACTGAATTTAGAGGGTGATATATTTAGTTTC 174224
|||||||||| ||||||||||||| ||||||||||||||||||||||||||||||||||
Old 174163 TCTGCCCAGGGAGCGGGAGCCGCTCGAAGACTGAATTTAGAGGGTGATATATTTAGTTTC 174222</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YAL047C YAL047C]
| 55746
| 55746
| Substitution
| A
| G
|-style="height:30px; width:30px; text-align:center;"
| 55954
| 55954
| Substitution
| A
| T
|-
| || colspan="6" |Nucleotide changes within the coding region of SPC72/[https://www.yeastgenome.org/locus/YAL047C YAL047C] resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 302 is now Asparagine rather than Isoleucine.
<pre>New 55726 TTTCCAAATTGTTTATCAAGACAGATTGCGATTCGATCTTTTCCTTCAGTTGGGAAATCA 55785
||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||
Old 55727 TTTCCAAATTGTTTATCAAAACAGATTGCGATTCGATCTTTTCCTTCAGTTGGGAAATCA 55786

New 55916 AATGGAATTTATAAATTGATCATATTCTTTGTGCAAATTTTCTATGACAATCTCTAATTG 55975
||||||||||||||||||||||||||||||||||||| ||||||||||||||||||||||
Old 55917 AATGGAATTTATAAATTGATCATATTCTTTGTGCAAAATTTCTATGACAATCTCTAATTG 55976</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YAL060W YAL060W]
| 36120
| 36120
| Substitution
| C
| A
|-
| || colspan="6" |A single nucleotide substitution within the coding region of BDH1/[https://www.yeastgenome.org/locus/YAL060W YAL060W] resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 322 is now Aspartic Acid rather than Alanine.
<pre>New 36106 TATGTTGTCGAAGACTTCGAAGAAGTTGTTCGTGCCATCCACAACGGAGACATCGCCATG 36165
||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||
Old 36107 TATGTTGTCGAAGCCTTCGAAGAAGTTGTTCGTGCCATCCACAACGGAGACATCGCCATG 36166</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YAL010C YAL010C]
| 134852
| 134854
| Substitution
| TTG
| ATT
|-
| || colspan="6" |A single nucleotide substitution within the coding region of MDM10/[https://www.yeastgenome.org/locus/YAL010C YAL010C] resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 272 is now Asparagine rather than Glutamine.
<pre>New 134813 TGGCCGAATATGTGGAGGATATATGGCCGAATAATGGATTCCAAGATAATGTCAAAGTTA 134872
||||||||||||||||||||||||||||||||||||| | ||||||||||||||||||||
Old 134815 TGGCCGAATATGTGGAGGATATATGGCCGAATAATGGTTGCCAAGATAATGTCAAAGTTA 134874</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YAL017W YAL017W]
| 120442
| 120442
| Substitution
| C
| G
|-
| || colspan="6" |A single nucleotide substitution within the coding region of PSK1/[https://www.yeastgenome.org/locus/YAL017W YAL017W] resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 73 is now Glutamic Acid rather than Glutamine.
<pre>New 120415 CGAATAAAAAGGAAGGTGATGAGTTCGAGCAAAGTTTAAGAGATACATTTGCGAGCTTTC 120474
|||||||||||||||||||||||||| |||||||||||||||||||||||||||||||||
Old 120416 CGAATAAAAAGGAAGGTGATGAGTTCCAGCAAAGTTTAAGAGATACATTTGCGAGCTTTC 120475</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YAL020C YAL020C]
| 113702
| 113703
| Substitution
| CG
| GC
|-
| || colspan="6" |The substitution of two nucleotides within the coding region of ATS1/[https://www.yeastgenome.org/locus/YAL020C YAL020C] resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 305 is now Glycine rather than Alanine.
<pre>New 113685 GCAGTCCAGGCTGGGAGCCCTTTTGCGGGCCGCAGTTGCCATGCTCTCCCCAGCCCCAGC 113744
|||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 113896 GCAGTCCAGGCTGGGACGCCTTTTGCGGGCCGCAGTTGCCATGCTCTCCCCAGCCCCAGC 113745</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YAL025C YAL025C]
| 100399
| 100399
| Substitution
| A
| C
|-
| || colspan="6" |A single nucleotide substitution within the coding region of MAK16/[https://www.yeastgenome.org/locus/YAL025C YAL025C] resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 250 is now Glutamic Acid rather than Glutamine.
<pre>New 100375 GCTTTCACTGTCGCTTTCGCTTTCACTGGCGCTGGAAGCTTCTCTGTCAGAGTCAGCTAA 100434
||||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||
Old 100376 GCTTTCACTGTCGCTTTCGCTTTGACTGGCGCTGGAAGCTTCTCTGTCAGAGTCAGCTAA 100435</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="5"| 2011-02-03
| rowspan="5"| [https://www.yeastgenome.org/locus/YAL056W YAL056W]
| 40231
| 40231
| Substitution
| C
| G
|-style="height:30px; width:30px; text-align:center;"
| 41240
| 41240
| Substitution
| A
| G
|-style="height:30px; width:30px; text-align:center;"
| 41664
| 41664
| Substitution
| T
| G
|-style="height:30px; width:30px; text-align:center;"
| 41700
| 41700
| Substitution
| C
| A
|-style="height:30px; width:30px; text-align:center;"
| 41703
| 41703
| Substitution
| C
| A
|-
| || colspan="6" |Nucleotide changes within the coding region of GPB2/[https://www.yeastgenome.org/locus/YAL056W YAL056W] resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 661 is now Valine rather than Isoleucine, residue 802 is now Cysteine rather than Phenylalanine, and residues 814-815 are now ED rather than AA.
<pre>New 40196 ATTTTTTTGTAGACGGAATAAAGAACTTACCTCCGCCTTTACTACCTCAAGTGATTAATA 40255
|||||||||||||||||||||||||||||||||| |||||||||||||||||||||||||
Old 40197 ATTTTTTTGTAGACGGAATAAAGAACTTACCTCCCCCTTTACTACCTCAAGTGATTAATA 40256

New 41216 ACGATAATTTGGAAAATTATATAGTCAATCCAGGGAGAAAATCGTCATCTATTCCAATGA 41275
||||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||
Old 41217 ACGATAATTTGGAAAATTATATAATCAATCCAGGGAGAAAATCGTCATCTATTCCAATGA 41276

New 41651 TAAGCACGCAGTGTTGGGAAGAACATAAAATTACTCTGTCCAAGAAGGAAGACGATGAGG 41710
|||||||||||| ||||||||||||||||||||||||||||||||||| || ||||||||
Old 41652 TAAGCACGCAGTTTTGGGAAGAACATAAAATTACTCTGTCCAAGAAGGCAGCCGATGAGG 41711</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YAL059C-A YAL059C-A], [https://www.yeastgenome.org/locus/YAL059W YAL059W]
| 36814
| 36814
| Substitution
| A
| C
|-
| || colspan="6" |A single nucleotide substitution within the coding regions of overlapping ORFs ECM1/[https://www.yeastgenome.org/locus/YAL059W YAL059W] and [https://www.yeastgenome.org/locus/YAL059C-A YAL059C-A] resulted in altered protein sequences for both ORFs. The start, stop, and reading frames remain the same for both proteins, but ECM1/[https://www.yeastgenome.org/locus/YAL059W YAL059W] protein residue 102 is now Alanine rather than Aspartic Acid, and [https://www.yeastgenome.org/locus/YAL059C-A YAL059C-A] protein residue 36 is now Alanine rather than Serine.
<pre>New 36776 AAGAAGTTAAATAAAAAGGCTCTGGAAGACAAACTGGCCAACTCTATTTCATCCATGGAC 36835
||||||||||||||||||||||||||||||||||||| ||||||||||||||||||||||
Old 36777 AAGAAGTTAAATAAAAAGGCTCTGGAAGACAAACTGGACAACTCTATTTCATCCATGGAC 36836</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/HRA1 HRA1]
| 99841
| 99841
| Substitution
| A
| T
|-
| || colspan="6" |A single nucleotide substitution was made within ncRNA [https://www.yeastgenome.org/locus/HRA1 HRA1].
<pre>New 99825 TTCAACTTAGTGGCATTAAACAGATTTGGGTTTTCTGGCAAAAAAAGCCAATCACGTGAT 99884
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Old 99826 TTCAACTTAGTGGCAATAAACAGATTTGGGTTTTCTGGCAAAAAAAGCCAATCACGTGAT 99885</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/ARS110 ARS110], [https://www.yeastgenome.org/locus/YAR019W-A YAR019W-A]
| 175378
| 175378
| Substitution
| T
| C
|-style="height:30px; width:30px; text-align:center;"
| 175371
| 175371
| Deletion
| T
|
|-
| || colspan="6" |A single nucleotide deletion and a single nucleotide substitution were made in the intergenic region between ORF [https://www.yeastgenome.org/locus/YAR019W-A YAR019W-A] and [https://www.yeastgenome.org/locus/ARS110 ARS110].
<pre>New 175355 GCCCAATTTTGATTATGCC-TCTTTTCCATACACGACGCCAGAGGACATTATTACATTAC 175413
||||||||||||||||||| |||||| |||||||||||||||||||||||||||||||||
Old 175352 GCCCAATTTTGATTATGCCTTCTTTTTCATACACGACGCCAGAGGACATTATTACATTAC 175411</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/ARS106 ARS106], [https://www.yeastgenome.org/locus/YAL038W YAL038W]
| 70874
| 70874
| Substitution
| A
| G
|-style="height:30px; width:30px; text-align:center;"
| 70794
| 70794
| Substitution
| C
| G
|-
| || colspan="6" |Two separate single nucleotide substitutions were made in the intergenic region between [https://www.yeastgenome.org/locus/ARS106 ARS106] and ORF CDC19/[https://www.yeastgenome.org/locus/YAL038W YAL038W].
<pre>New 70746 GGTTTTCCGACTTTATTTGAGATGACTTGAGATGTGTGTCAATGCTAGTATTTTGGAGAT 70805
||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
Old 70747 GGTTTTCCGACTTTATTTGAGATGACTTGAGATGTGTGTCAATGCTACTATTTTGGAGAT 70806
New 70856 TTATTTTTTTTTTGTTAGAATTGATCCAAATGTAAATAAACAATCACAAGGAAAAAAAAA 70915
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 70857 TTATTTTTTTTTTGTTAAAATTGATCCAAATGTAAATAAACAATCACAAGGAAAAAAAAA 70916</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/ARS104 ARS104], [https://www.yeastgenome.org/locus/YAL063C YAL063C]
| 28953
| 28953
| Insertion
|
| T
|-style="height:30px; width:30px; text-align:center;"
| 28069
| 28069
| Deletion
| T
|
|-
| || colspan="6" |A single nucleotide deletion and a single nucleotide insertion were made in the intergenic region between ORF FLO9/[https://www.yeastgenome.org/locus/YAL063C YAL063C] and [https://www.yeastgenome.org/locus/ARS104 ARS104].
<pre>New 28027 GTAAATAAGAAGGAAGAACGTTATGTTATTAATGGACTTTT-AGTGTCATCGAATTTTAT 28085
||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||||
Old 28028 GTAAATAAGAAGGAAGAACGTTATGTTATTAATGGACTTTTTAGTGTCATCGAATTTTAT 28087
New 28916 AGTAAACAAGAGATACCTAATTTCACAGCCACTTTTTGTTGCGGACACTGACGGGATGTG 28975
|||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
Old 28918 AGTAAACAAGAGATACCTAATTTCACAGCCACTTTT-GTTGCGGACACTGACGGGATGTG 28976</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YAR023C YAR023C], [https://www.yeastgenome.org/locus/SUP56 tL(CAA)A]
| 180961
| 180961
| Insertion
|
| CAAA
|-
| || colspan="6" |A tetranucleotide insertion was made in the intergenic region between ORF [https://www.yeastgenome.org/locus/YAR023C YAR023C] and tRNA-Leu SUP56/[https://www.yeastgenome.org/locus/SUP56 tL(CAA)A].
<pre>New 180942 TTCCCATTACAATGCCGAATAGCAAAATATGTAGTAGAACACGTACACGCATGATAATTA 181001
|||||||||||||||||||||| ||||||||||||||||||||||||||||||||||
Old 180940 TTCCCATTACAATGCCGAATAG----ATATGTAGTAGAACACGTACACGCATGATAATTA 180995</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YAL041W YAL041W], [https://www.yeastgenome.org/locus/YAL042W YAL042W]
| 62767
| 62767
| Substitution
| A
| G
|-
| || colspan="6" |A single nucleotide substitution was made in the intergenic region between ORFs ERV46/[https://www.yeastgenome.org/locus/YAL042W YAL042W] and CDC24/[https://www.yeastgenome.org/locus/YAL041W YAL041W].
<pre>New 62756 TAGGATAGCAGAAGAGTACCATTGCTGTTATCATTTGTTGCCTAGCCCTATCAAGACCTG 62815
|||||||||| |||||||||||||||||||||||||||||||||||||||||||||||||
Old 62757 TAGGATAGCAAAAGAGTACCATTGCTGTTATCATTTGTTGCCTAGCCCTATCAAGACCTG 62816</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YAR047C YAR047C], [https://www.yeastgenome.org/locus/YAR050W YAR050W]
| 203327
| 203327
| Insertion
|
| T
|-style="height:30px; width:30px; text-align:center;"
| 202933
| 202933
| Insertion
|
| A
|-
| || colspan="6" |Two separate single nucleotide insertions were made in the intergenic region between ORFs [https://www.yeastgenome.org/locus/YAR047C YAR047C] and FLO1/[https://www.yeastgenome.org/locus/YAR050W YAR050W].
<pre>New 202902 GCTCATTAATTGCCCTCACAAGAATTTGGAAGTGCGTAGAACAGGTAAAAGATTGTACTA 202961
||||||||||||||||||||||||||||||||||||||| ||||||||||||||||||||
Old 202895 GCTCATTAATTGCCCTCACAAGAATTTGGAAGTGCGTAG-ACAGGTAAAAGATTGTACTA 202953
New 203322 TTCACTCTTGCTCGTTTGATGTAAGCTCTCTTCCGGGTTCTTATTTTTAATTCTTGTCAC 203381
|||||||||||||| |||||||||||||||||||||||||||||||||||||||||||||
Old 203314 TTCACTCTTGCTCG-TTGATGTAAGCTCTCTTCCGGGTTCTTATTTTTAATTCTTGTCAC 203372</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YAR042W YAR042W], [https://www.yeastgenome.org/locus/YAR047C YAR047C]
| 198900
| 198900
| Insertion
|
| A
|-
| || colspan="6" |A single nucleotide insertion was made in the intergenic region between ORFs SWH1/[https://www.yeastgenome.org/locus/YAR042W YAR042W] and [https://www.yeastgenome.org/locus/YAR047C YAR047C].
<pre>New 198882 TAAGCCCCTTTTATGGATGCATGAGAAAAAAAAAAAGGTTTGCTACAACCATCTCAGGTC 198941
||||||||||||||||||||||||| ||||||||||||||||||||||||||||||||||
Old 198876 TAAGCCCCTTTTATGGATGCATGAG-AAAAAAAAAAGGTTTGCTACAACCATCTCAGGTC 198934</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="6"| 2011-02-03
| rowspan="6"| [https://www.yeastgenome.org/locus/YAR020C YAR020C], [https://www.yeastgenome.org/locus/YAR023C YAR023C]
| 178647
| 178647
| Substitution
| T
| C
|-style="height:30px; width:30px; text-align:center;"
| 178638
| 178638
| Deletion
| G
|
|-style="height:30px; width:30px; text-align:center;"
| 178618
| 178618
| Insertion
|
| A
|-style="height:30px; width:30px; text-align:center;"
| 178601
| 178601
| Deletion
| A
|
|-style="height:30px; width:30px; text-align:center;"
| 178256
| 178256
| Substitution
| G
| C
|-style="height:30px; width:30px; text-align:center;"
| 177135
| 177135
| Insertion
|
| T
|-
| || colspan="6" |Several nucleotide sequence changes were made in the intergenic region between ORFs PAU7/[https://www.yeastgenome.org/locus/YAR020C YAR020C] and [https://www.yeastgenome.org/locus/YAR023C YAR023C].
<pre>New 177104 CAAAGCTGATCAAGCCGCTGTATTTATATGAAACTTTGAACAACTACATCTGCACACATG 177163
|||||||||||||||||||||||||||||||||| |||||||||||||||||||||||||
Old 177102 CAAAGCTGATCAAGCCGCTGTATTTATATGAAAC-TTGAACAACTACATCTGCACACATG 177160
New 178244 ACAATTTAACCATGGCAGGTTAAAATATTACTGCGATCAGTAAAAATGGGGATATCACCT 178303
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Old 178241 ACAATTTAACCATGGGAGGTTAAAATATTACTGCGATCAGTAAAAATGGGGATATCACCT 178300
New 178599 ATTGT-AGATTGTATCGTTCGAGAAACGTCAGGCATGATAGAT-GTTGCAATCACAGGAC 178656
||||| ||||||||||||||||| ||||||||||||||||||| |||||||| |||||||
Old 178596 ATTGTAAGATTGTATCGTTCGAG-AACGTCAGGCATGATAGATGGTTGCAATTACAGGAC 178654</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="10"| 2011-02-03
| rowspan="10"| [https://www.yeastgenome.org/locus/YAR018C YAR018C], [https://www.yeastgenome.org/locus/YAR019C YAR019C]
| 172170
| 172170
| Insertion
|
| T
|-style="height:30px; width:30px; text-align:center;"
| 172042
| 172042
| Insertion
|
| T
|-style="height:30px; width:30px; text-align:center;"
| 172041
| 172041
| Insertion
|
| T
|-style="height:30px; width:30px; text-align:center;"
| 172020
| 172020
| Deletion
| A
|
|-style="height:30px; width:30px; text-align:center;"
| 172018
| 172018
| Deletion
| A
|
|-style="height:30px; width:30px; text-align:center;"
| 171983
| 171983
| Deletion
| G
|
|-style="height:30px; width:30px; text-align:center;"
| 171975
| 171977
| Deletion
| CTA
|
|-style="height:30px; width:30px; text-align:center;"
| 171972
| 171972
| Substitution
| C
| T
|-style="height:30px; width:30px; text-align:center;"
| 171968
| 171968
| Deletion
| C
|
|-style="height:30px; width:30px; text-align:center;"
| 171882
| 171882
| Insertion
|
| C
|-
| || colspan="6" |Several nucleotide sequence changes were made in the intergenic region between ORFs KIN3/[https://www.yeastgenome.org/locus/YAR018C YAR018C] and CDC15/[https://www.yeastgenome.org/locus/YAR019C YAR019C].
<pre>New 171843 GTAATGAAAAAATTCAGAAACCTTAAAAAAAAAACTTGGCTGTAACCTATCGGAAGACTG 171902
||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||
Old 171838 GTAATGAAAAAATTCAGAAACCTTAAAAAAAAAACTTGGCTGTAA-CTATCGGAAGACTG 171896
New 171953 CTAGAAACATTTAACAAAATG-CACTTT---GAGTC-GTTCATACATTTAATCCCCAATT 172007
||||||||||||||||||||| ||| || ||||| |||||||||||||||||||||||
Old 171947 CTAGAAACATTTAACAAAATGCCACCTTCTAGAGTCGGTTCATACATTTAATCCCCAATT 172006
New 172008 GAAAAAAAAAA-G-AAAAGAAAAAAAGCATATATATGTATATGCTTTTTTATCATTACTG 172065
||||||||||| | ||||||||||||||||||||| | ||||||||||||||||||||||
Old 172007 GAAAAAAAAAAAGAAAAAGAAAAAAAGCATATATA-G-ATATGCTTTTTTATCATTACTG 172064
New 172126 GGAAGGTTCACAATTCTATATATAGTGTTAATGTAATGCTGTATTATTTCTCTATATATG 172185
|||||||||||||||||||||||||||||||||||||||||||||| |||||||||||||
Old 172125 GGAAGGTTCACAATTCTATATATAGTGTTAATGTAATGCTGTATTA-TTCTCTATATATG 172183</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YAR007C YAR007C], [https://www.yeastgenome.org/locus/YAR008W YAR008W]
| 158934
| 158934
| Insertion
|
| G
|-
| || colspan="6" |A single nucleotide insertion was made in the intergenic region between ORFs RFA1/[https://www.yeastgenome.org/locus/YAR007C YAR007C] and SEN34/[https://www.yeastgenome.org/locus/YAR008W YAR008W].
<pre>New 158923 TAACATATATGCAAAAAGAACGGCAAAAGGCGAGGAGGTTTTTATGCCACCGCTAGTATT 158982
|||||||||| |||||||||||||||||||||||||||||||||||||||||||||||||
Old 158925 TAACATATAT-CAAAAAGAACGGCAAAAGGCGAGGAGGTTTTTATGCCACCGCTAGTATT 158983</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/CEN1 CEN1], [https://www.yeastgenome.org/locus/YAR002W YAR002W]
| 152189
| 152190
| Substitution
| CA
| AC
|-
| || colspan="6" |A dinucleotide substitution was made in the intergenic region between [https://www.yeastgenome.org/locus/CEN1 CEN1] and ORF NUP60/[https://www.yeastgenome.org/locus/YAR002W YAR002W]
<pre>New 152153 ATATATTTACAAGTGAAAGCTTATTGTAATGTGTACTTTTAAACATCAAATAACAGACCT 152212
|||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||
Old 152155 ATATATTTACAAGTGAAAGCTTATTGTAATGTGTCATTTTAAACATCAAATAACAGACCT 152214</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="5"| 2011-02-03
| rowspan="5"| [https://www.yeastgenome.org/locus/YAL067C YAL067C], [https://www.yeastgenome.org/locus/YAL067W-A YAL067W-A]
| 6454
| 6454
| Deletion
| C
|
|-style="height:30px; width:30px; text-align:center;"
| 5927
| 5927
| Insertion
|
| G
|-style="height:30px; width:30px; text-align:center;"
| 5244
| 5244
| Substitution
| G
| A
|-style="height:30px; width:30px; text-align:center;"
| 3981
| 3982
| Substitution
| AT
| TA
|-style="height:30px; width:30px; text-align:center;"
| 3836
| 3836
| Deletion
| C
|
|-
| || colspan="6" |Several nucleotide sequence changes were made in the intergenic region between ORFs [https://www.yeastgenome.org/locus/YAL067W-A YAL067W-A] and SEO1/[https://www.yeastgenome.org/locus/YAL067C YAL067C].
<pre>New 3791 CTTGGTAGTAACCATAATATTACCCAGGTACGAAACGCTAAGAAC-TTGAAAGACTCATA 3849
||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||
Old 3791 CTTGGTAGTAACCATAATATTACCCAGGTACGAAACGCTAAGAACCTTGAAAGACTCATA 3850
New 3960 TTTCCATTTTGATAATGAGCTAGTGATCCGGAAAGCTACTTTATGATGTTTCAAGGCCTG 4019
|||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||
Old 3961 TTTCCATTTTGATAATGAGCATGTGATCCGGAAAGCTACTTTATGATGTTTCAAGGCCTG 4020
New 5220 TAAATAGTTTTCAACTGCTGGTGATAAATCAATAATTTATGTTCTTAACCTAACATTTGA 5279
||||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||
Old 5221 TAAATAGTTTTCAACTGCTGGTGGTAAATCAATAATTTATGTTCTTAACCTAACATTTGA 5280
New 5880 AACTGCATTCGGACTATGAAAGAAAAAATGGTAGTAGCAAAGGATAGGCATCGCCGTATT 5939
||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
Old 5881 AACTGCATTCGGACTATGAAAGAAAAAATGGTAGTAGCAAAGGATAG-CATCGCCGTATT 5939
New 6420 AAGTTTCTTAAATAACCCGGATTGGTTAGGTTCA-GCCATGCCTGGCGCGTACATTGAGG 6478
|||||||||||||||||||||||||||||||||| |||||||||||||||||||||||||
Old 6420 AAGTTTCTTAAATAACCCGGATTGGTTAGGTTCACGCCATGCCTGGCGCGTACATTGAGG 6479</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YAL064C-A YAL064C-A], [https://www.yeastgenome.org/locus/YAL064W YAL064W]
| 16500
| 16500
| Deletion
| G
|
|-style="height:30px; width:30px; text-align:center;"
| 16470
| 16470
| Deletion
| T
|
|-style="height:30px; width:30px; text-align:center;"
| 16457
| 16457
| Substitution
| G
| A
|-
| || colspan="6" |A single nucleotide substitution and two separate single nucleotide deletions were made in the intergenic region between ORFs [https://www.yeastgenome.org/locus/YAL064C-A YAL064C-A] and [https://www.yeastgenome.org/locus/YAL064W YAL064W].
<pre>New 16449 TCTGTGGAAAATAAGAAATT-CAGCACCAGTAAAAGACGAGAAATATAGG-CACATAAAT 16506
||||||| |||||||||||| ||||||||||||||||||||||||||||| |||||||||
Old 16450 TCTGTGGGAAATAAGAAATTTCAGCACCAGTAAAAGACGAGAAATATAGGGCACATAAAT 16509</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YAL063C YAL063C], [https://www.yeastgenome.org/locus/YAL063C-A YAL063C-A]
| 23253
| 23253
| Insertion
|
| T
|-
| || colspan="6" |A single nucleotide insertion was made in the intergenic region between ORFs [https://www.yeastgenome.org/locus/YAL063C-A YAL063C-A] and FLO9/[https://www.yeastgenome.org/locus/YAL063C YAL063C].
<pre>New 23217 TTTGCTCATCATTGGATAATTTCTTTTTTTTTTTTTGATGCATCCAAACTTGGACCCCTT 23276
||||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||
Old 23219 TTTGCTCATCATTGGATAATTTCTTTTTTTTTTTT-GATGCATCCAAACTTGGACCCCTT 23277</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YAL021C YAL021C], [https://www.yeastgenome.org/locus/YAL022C YAL022C]
| 110470
| 110471
| Substitution
| CG
| GC
|-
| || colspan="6" |A dinucleotide substitution was made in the intergenic region between ORFs FUN26/[https://www.yeastgenome.org/locus/YAL022C YAL022C] and CCR4/[https://www.yeastgenome.org/locus/YAL021C YAL021C].
<pre>New 110455 GCGTTTGATGATAAGCTGTCGCCGTAACGTAAATCATTCATCCTTTCCTATGATTTTTTA 110514
|||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Old 110456 GCGTTTGATGATAACGTGTCGCCGTAACGTAAATCATTCATCCTTTCCTATGATTTTTTA 110515</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YAL010C YAL010C], [https://www.yeastgenome.org/locus/YAL011W YAL011W]
| 134125
| 134125
| Insertion
|
| C
|-
| || colspan="6" |A single nucleotide substitution was made in the intergenic region between ORFs SWC3/[https://www.yeastgenome.org/locus/YAL011W YAL011W] and MDM10/[https://www.yeastgenome.org/locus/YAL010C YAL010C].
<pre>New 134093 ATTCTGCTTTAACGCCATTATGATTATACACATTGTATTACTTATTTTTTAACCTGTATA 134152
|||||||||||||||||||||||||||||| |||||||||||||||||||||||||||||
Old 134096 ATTCTGCTTTAACGCCATTATGATTATACA-ATTGTATTACTTATTTTTTAACCTGTATA 134154</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/TEL01R TEL01R] TEL01R-XC
| 229568
| 229568
| Insertion
|
| G
|-
| || colspan="6" |A single nucleotide insertion was made within the right telomere of Chromosome 1, [https://www.yeastgenome.org/locus/TEL01R TEL01R] specifically within the X element Core sequence TEL01R-XC.
<pre>New 229542 ATTACGCATGGAGTTAAGAGTATTTACATGATAATTGGGGTTCCGTGATTCATTATAGAT 229601
|||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
Old 229533 ATTACGCATGGAGTTAAGAGTATTTACATGATAATT-GGGTTCCGTGATTCATTATAGAT 229591</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text]
|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2008-03-05
| rowspan="3"| [https://www.yeastgenome.org/locus/YAL044C YAL044C]
| 58424
| 58424
| Substitution
| C
| T
|-style="height:30px; width:30px; text-align:center;"
| 58247
| 58247
| Substitution
| A
| C
|-style="height:30px; width:30px; text-align:center;"
| 58196
| 58196
| Substitution
| A
| C
|-
| || colspan="6" |Three single base substitutions were made within ORF [https://www.yeastgenome.org/locus/YAL044C YAL044C]/GCV3 to correct errors in the systematic reference sequence for Chromosome I: Two separate A -> C transversions at 58196 and 58247, and a C -> T transition at 58424. These errors were verified by sequencing in 3 different strains, all of ResGen BY4741 (S288C) background. SGD thanks Michael E. Rice for bringing these errors to our attention, and for verifying the correct sequence.
<pre>New: 58191 TTGGGCAATCTCAGTGCCCACTTCTGGCAACTCAACATAGGTAGCGTCCCCTAAGGCATC 58250
||||| |||||||||||||||||||||||||||||||||||||||||||||||||| |||
Old: 58191 TTGGGAAATCTCAGTGCCCACTTCTGGCAACTCAACATAGGTAGCGTCCCCTAAGGAATC 58250

New: 58251 AGTGGCGTATTTTGTAATTCCGACAAAGGCAGTCTTGTCCTGATGCACAGCTATCCACTC 58310
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Old: 58251 AGTGGCGTATTTTGTAATTCCGACAAAGGCAGTCTTGTCCTGATGCACAGCTATCCACTC 58310

New: 58311 ATGTTGGGAAGTGTACCTCACGGCTTGAGGTCCTTGGGATGAGTACAAAAATGGTAGTTT 58370
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Old: 58311 ATGTTGGGAAGTGTACCTCACGGCTTGAGGTCCTTGGGATGAGTACAAAAATGGTAGTTT 58370

New: 58371 ATTCTTGTTTAGGGCATTGCCGGAGCTGTTTCTCAAAAACAATTTGCTCACAGTGGGCAT 58430
||||||||||||||||||||||||||||||||||||||||||||||||||||| ||||||
Old: 58371 ATTCTTGTTTAGGGCATTGCCGGAGCTGTTTCTCAAAAACAATTTGCTCACAGCGGGCAT 58430</pre>
|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2007-04-05
| rowspan="3"| [https://www.yeastgenome.org/locus/YAL004W YAL004W], [https://www.yeastgenome.org/locus/YAL005C YAL005C]
| 140169
| 140169
| Substitution
| A
| G
|-style="height:30px; width:30px; text-align:center;"
| 140182
| 140182
| Substitution
| A
| G
|-style="height:30px; width:30px; text-align:center;"
| 140811
| 140811
| Substitution
| A
| G
|-
| || colspan="6" |Three single nucleotide substitutions were made within the coding sequence of SSA1 (at nucleotide positions 623, 1252, and 1265 relative to the SSA1 coding sequence), based on the sequence reported by Slater and Craig (1989) and corresponding to GenBank entry X12926. These changes result in phenylalanine to serine changes at amino acid residues 208 and 422 and a change from serine to proline at amino acid residue 418. Thanks to Andreas Bracher for bringing these corrections to our attention.
Note that the change at position 623 of SSA1 also affects the coding sequence of the Dubious ORF [https://www.yeastgenome.org/locus/YAL004W YAL004W].

<pre>638 ATACCGTCTTCAATGGACAACAAAGAGAC 610 new sequence, coordinates relative to SSA1 coding region
||||||||||||||| |||||||||||||
140796 ATACCGTCTTCAATGAACAACAAAGAGAC 140824 old sequence, chromosomal coordinates

1279 TGGAAAAGATCTCGGACTTCTTTGTTGGAATGGTAGAGTTT 1239 new sequence, coordinates relative to SSA1 coding region
|||||||||||||| |||||||||||| |||||||||||||
140155 TGGAAAAGATCTCGAACTTCTTTGTTGAAATGGTAGAGTTT 140195 old sequence, chromosomal coordinates</pre>
Slater MR and Craig EA (1989) The SSA1 and SSA2 genes of the yeast Saccharomyces cerevisiae. Nucleic Acids Res 17(2):805-6
|- style="height:30px; width:30px; text-align:center;"
| 2006-01-19
| [https://www.yeastgenome.org/locus/YAR042W YAR042W]
| 193355
| 193355
| Substitution
| G
| A
|-
| || colspan="6" |When confirming the G nucleotide insertion that resulted in the merger of SWH1/[https://www.yeastgenome.org/locus/YAR042W YAR042W] and OSH1/[https://www.yeastgenome.org/locus/YAR044W YAR044W] (see 2003-09-27), SGD detected an additional sequencing error. The substitution of an A nt for a G nt changes amino acid 248 from a serine to an asparagine.
Substitute an A nt for the G nt at 193355
<pre>New: 193341 CGACACCGCCACCAACACCAAGATCGCCATC 193371
|||||||||||||| ||||||||||||||||
Old: 193341 CGACACCGCCACCAGCACCAAGATCGCCATC 193371</pre>
|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2004-07-20
| rowspan="2"| [https://www.yeastgenome.org/locus/YAL051W YAL051W]
| 51694
| 51694
| Deletion
| G
|
|-style="height:30px; width:30px; text-align:center;"
| 51688
| 51688
| Deletion
| G
|
|-
| || colspan="6" |The work of Kellis et al. 2003 predicted the deletion of 2 separate G nucleotides in [https://www.yeastgenome.org/locus/YAL051W YAL051W] at chromosomal coordinates 51688 and 51694, and these sequence errors were confirmed in S288C by SGD. As a consequence of these changes, [https://www.yeastgenome.org/locus/YAL051W YAL051W] was shortened at the 3' end, altering the C-terminus and decreasing the size of the predicted protein from 1062 to 1047 amino acids.
<pre>New: 51666 TTTATTTGATTATGACTTTTTG-TTTGG-CAATGACTTTGCTTAAAAATTTTCTTTCCAA 51723
|||||||||||||||||||||| ||||| |||||||||||||||||||||||||||||||
Old: 51666 TTTATTTGATTATGACTTTTTGGTTTGGGCAATGACTTTGCTTAAAAATTTTCTTTCCAA 51725</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54 Errata] 
|- style="height:30px; width:30px; text-align:center;"
| 2004-01-30
| [https://www.yeastgenome.org/locus/YAR014C YAR014C]
| 166772
| 166772
| Deletion
| G
|
|-
| || colspan="6" |Kellis et al. 2003 predicted and confirmed the deletion of a single G nucleotide at chromosomal coordinate 166772. As a consequence of this sequence change, [https://www.yeastgenome.org/locus/YAR014C YAR014C] was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 702 to 707 amino acids.
<pre>New: 166731 TTGTAAGGACAATATCATTTACGAATAATTTCATCCAATTG-TTTCATCAACACA 166784
||||||||||||||||||||||||||||||||||||||||| |||||||||||||
Old: 166731 TTGTAAGGACAATATCATTTACGAATAATTTCATCCAATTGGTTTCATCAACACA 166785</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54 Errata] 
|- style="height:30px; width:30px; text-align:center;"
| 2004-01-24
| [https://www.yeastgenome.org/locus/YAL056W YAL056W]
| 41778
| 41778
| Insertion
|
| G
|-
| || colspan="6" |Kellis et al. 2003 predicted and confirmed the insertion of a single G nucleotide after the T at chromosomal coordinate 41778. As a consequence of this sequence change, [https://www.yeastgenome.org/locus/YAL056W YAL056W] was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein increasing from 847 to 880 amino acids.
<pre>New: 41724 GCGAAAATGAAGATACAAATTCAAATATAGTAGTTGGTGTCGGTGGCACTTCTTTGCAAT 41783
||||||||||||||||||||||||||||||||||||||||||||||||||||||| ||||
Old: 41724 GCGAAAATGAAGATACAAATTCAAATATAGTAGTTGGTGTCGGTGGCACTTCTTT-CAAT 41782</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54 Errata] 
|- style="height:30px; width:30px; text-align:center;"
| 2004-01-22
| [https://www.yeastgenome.org/locus/YAL002W YAL002W]
| 143848
| 143848
| Insertion
|
| C
|-
| || colspan="6" |Kellis et al. 2003 and Cliften et al. 2003 predicted and confirmed the insertion of a single C nucleotide after the C at chromosomal coordinate 143848. As a consequence of this sequence change, [https://www.yeastgenome.org/locus/YAL002W YAL002W] was extended at the 5' end, altering the N-terminus and increasing the size of the predicted protein from 1176 to 1274 amino acids.
<pre>New: 143826 ATCTAGTTCTTCATATACGGCACCTCCCCTGAACGAAGATGGTCCTAAAGGGGTAGCTTC 143885
||||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||
Old: 143826 ATCTAGTTCTTCATATACGGCAC-TCCCCTGAACGAAGATGGTCCTAAAGGGGTAGCTTC 143884</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54 Errata] 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 
|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2003-12-17
| rowspan="2"| [https://www.yeastgenome.org/locus/YAL013W YAL013W]
| 130239
| 130239
| Insertion
|
| C
|-style="height:30px; width:30px; text-align:center;"
| 130246
| 130247
| Substitution
| CG
| GC
|-
| || colspan="6" |Kellis et al. 2003 and Brachat et al. 2003 predicted and confirmed the insertion of a single C nucleotide after the C at position 130239 on Chromosome I. As a consequence of this sequence change, [https://www.yeastgenome.org/locus/YAL013W YAL013W] was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 362 to 420 amino acids. They also found an additional seqeuncing error: the CG at 130246-130247 should be GC.
<pre>Old: 130201 ACTTGATAACAAGACGCTGAGCTGTATCACGGGCTACGC-AGCGCACGACAGCTGTGCTA 130259
||||||||||||||||||||||||||||||||||||||| |||||| ||||||||||||
New: 130201 ACTTGATAACAAGACGCTGAGCTGTATCACGGGCTACGCCAGCGCAGCACAGCTGTGCTA 130260</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54 Errata] 
'''Brachat S, et al.''' (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45. 
[https://www.yeastgenome.org/reference/S000073670 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12844361 PubMed] | [https://genomebiology.biomedcentral.com/articles/10.1186/gb-2003-4-7-r45 Full-Text] 
|- style="height:30px; width:30px; text-align:center;"
| 2003-09-27
| [https://www.yeastgenome.org/locus/YAR042W YAR042W], [https://www.yeastgenome.org/locus/YAR044W YAR044W]
| 193300
| 193300
| Insertion
|
| G
|-
| || colspan="6" |Insertion of a single G after the G at 193300 merged SWH1/[https://www.yeastgenome.org/locus/YAR042W YAR042W] and OSH1/[https://www.yeastgenome.org/locus/YAR044W YAR044W]. After merging [https://www.yeastgenome.org/locus/YAR042W YAR042W] (coordinates 192613-193383 (1-771)) and [https://www.yeastgenome.org/locus/YAR044W YAR044W] (coordinates 193599-196178 (1-2580)), the coordinates of the merged ORF, SWH1/[https://www.yeastgenome.org/locus/YAR042W YAR042W], are 192613-196179 (1-3567). OSH1 and [https://www.yeastgenome.org/locus/YAR044W YAR044W] are now aliases of SWH1/[https://www.yeastgenome.org/locus/YAR042W YAR042W]. This sequence change was predicted by several studies, then verified in S288c by SGD.
<pre>Old: 193261 CTTGAACACGGTGCTGACCCCTTCAAGAGAGACCGCAAGG-CAAACTGCCCATCGAGCTC 193319
|||||||||||||||||||||||||||||||||||||||| |||||||||||||||||||
New: 193261 CTTGAACACGGTGCTGACCCCTTCAAGAGAGACCGCAAGGGCAAACTGCCCATCGAGCTC 193320</pre>
Schmalix WA and Bandlow W (1994) SWH1 from yeast encodes a candidate nuclear factor containing ankyrin repeats and showing homology to mammalian oxysterol-binding protein. Biochim Biophys Acta 1219(1):205-10
Beh CT, et al. (2001) Overlapping functions of the yeast oxysterol-binding protein homologues. Genetics 157(3):1117-40 
[https://www.yeastgenome.org/reference/S000059993 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/11238399 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1461579 Full-Text] 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54 Errata] 
'''Brachat S, et al.''' (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45. 
[https://www.yeastgenome.org/reference/S000073670 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12844361 PubMed] | [https://genomebiology.biomedcentral.com/articles/10.1186/gb-2003-4-7-r45 Full-Text] 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 
|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2002-12-17
| rowspan="2"| [https://www.yeastgenome.org/locus/YAL023C YAL023C]
| 108137
| 108137
| Insertion
|
| CC
|-style="height:30px; width:30px; text-align:center;"
| 108143
| 108143
| Insertion
|
| G
|-
| || colspan="6" |Due to the insertion of CC after the C at 108137, and the insertion of a G after the G at 108143 in the systematic sequence of Chromosome I, the coordinates of PMT2/[https://www.yeastgenome.org/locus/YAL023C YAL023C] have been changed. Thanks to Verena Girrbach (verena.girrbach@biologie.uni-regensburg.de) for reporting this sequence error in the systematic sequence of PMT2/FUN25/[https://www.yeastgenome.org/locus/YAL023C YAL023C] to SGD.
<pre>Old: 108121 AGTCTGGGTAAATTTCC--AGAAGG-AAGTCCCAAGAACCGTTGTAGCCTGCCAAATAAC 108177
||||||||||||||||| |||||| ||||||||||||||||||||||||||||||||||
New: 108121 AGTCTGGGTAAATTTCCCCAGAAGGGAAGTCCCAAGAACCGTTGTAGCCTGCCAAATAAC 108180</pre>
|- style="height:30px; width:30px; text-align:center;"
| 2002-12-17
| [https://www.yeastgenome.org/locus/YAL014C YAL014C]
| 128441
| 128441
| Insertion
|
| T
|-
| || colspan="6" |Due to the insertion of a single T nucleotide after the T at coordinate 128441 in the systematic sequence of Chromosome I, the ORF SUN8/[https://www.yeastgenome.org/locus/YAL014C YAL014C] was extended 450 nucleotides in the 3' direction, making the protein product 150 amino acids longer at the C-terminus. Thanks to Lena Burri, Trevor Lithgow, and Hugh Pelham for reporting this sequence error in the systematic sequence of SYN8/UIP2/[https://www.yeastgenome.org/locus/YAL014C YAL014C] to SGD.
<pre>Old: 128398 TTCTAAATCAACCAGCAGCGAGTCGTTCTGAGAAACGATCTCAT-ATTAAGGTCCAGCGA 128456
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
New: 128401 TTCTAAATCAACCAGCAGCGAGTCGTTCTGAGAAACGATCTCATTATTAAGGTCCAGCGA 128460</pre>
Lewis MJ and Pelham HR (2002) A new yeast endosomal SNARE related to mammalian syntaxin 8. Traffic 3(12):922-9
|- style="height:30px; width:30px; text-align:center;"
| rowspan="6"| 1998-09-02
| rowspan="6"| [https://www.yeastgenome.org/locus/YAL062W YAL062W], [https://www.yeastgenome.org/locus/YAL063C YAL063C]
| 29254
| 29254
| Deletion
| A
|
|-style="height:30px; width:30px; text-align:center;"
| 29289
| 29289
| Deletion
| A
|
|-style="height:30px; width:30px; text-align:center;"
| 29290
| 29290
| Deletion
| A
|
|-style="height:30px; width:30px; text-align:center;"
| 29291
| 29291
| Deletion
| T
|
|-style="height:30px; width:30px; text-align:center;"
| 29307
| 29307
| Deletion
| A
|
|-style="height:30px; width:30px; text-align:center;"
| 29301
| 29301
| Substitution
| T
| A
|-
| || colspan="6" |The following changes were made to the systematic sequence of Chromosome I in the region encompassing features FLO9/[https://www.yeastgenome.org/locus/YAL063C YAL063C] and GDH3/[https://www.yeastgenome.org/locus/YAL062W YAL062W]: deletion of the A at 29254, deletion of AAT at 29289-29291, transversion of T to A at 29301, and deletion of the A at 29307.
<pre>Old: 29221 TGAAATCATACCTGCCAAGCTTGCTGCACTTGGAAAGGCAACTCCGTTTTTCAGAGATTA 29280
||||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||
New: 29221 TGAAATCATACCTGCCAAGCTTGCTGCACTTGGAA-GGCAACTCCGTTTTTCAGAGATTA 29279
Old: 29281 GATCCTTTAATTTTTTTTGATGAAAAAGGCAGCCAAGTTACGTCATAGAGAAAACTCCCT 29340
|||||||| ||||||||| ||||| |||||||||||||||||||||||||||||||||
New: 29280 GATCCTTT---TTTTTTTGAAGAAAA-GGCAGCCAAGTTACGTCATAGAGAAAACTCCCT 29335</pre>
|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 1998-09-02
| rowspan="3"| [https://www.yeastgenome.org/locus/YAR060C YAR060C], [https://www.yeastgenome.org/locus/YARCdelta8 YARCdelta8]
| 210810
| 210810
| Substitution
| T
| A
|-style="height:30px; width:30px; text-align:center;"
| 211011
| 211011
| Substitution
| C
| T
|-style="height:30px; width:30px; text-align:center;"
| 210804
| 210804
| Deletion
| T
|
|-
| || colspan="6" |The following changes were made to the systematic sequence of Chromosome I in the region encompassing features [https://www.yeastgenome.org/locus/YARCdelta8 YARCdelta8] and [https://www.yeastgenome.org/locus/YAR060C YAR060C]: deletion of the T at 210804, transversion of T to A at 210810, and transition of C to T at 211011.
<pre>Old: 210781 TTTCTCTTTGCTTGCATCTTTTTTCTTCCTTGCCAAAAAATAAAAGATACTCATTTTAAA 210840
||||||||||||||||||||||| ||||| ||||||||||||||||||||||||||||||
New: 210776 TTTCTCTTTGCTTGCATCTTTTT-CTTCCATGCCAAAAAATAAAAGATACTCATTTTAAA 210834
Old: 210961 GCCCTTCTACGGCTTCTTCTAACCAATTGTTCCCCGTGAGTTGCTTTCTCCGAAAACCTT 211020
|||||||||||||||||||||||||||||||||||||||||||||||||| |||||||||
New: 210955 GCCCTTCTACGGCTTCTTCTAACCAATTGTTCCCCGTGAGTTGCTTTCTCTGAAAACCTT 211014</pre>
|- style="height:30px; width:30px; text-align:center;"
| 1998-09-02
| [https://www.yeastgenome.org/locus/YAR050W YAR050W]
| 203939
| 203939
| Substitution
| T
| G
|-
| || colspan="6" |The following sequence change was made to the systematic sequence of Chromosome I within the ORF [https://www.yeastgenome.org/locus/YAR050W YAR050W]/FLO1: transversion of T to G at 203939.
<pre>Old: 203881 CAATTCTATCAGTAGGTGGTGCAACCGCGTTCAACTGTTGTGCTCAACAGCAACCGCCTA 203940
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||| |
New: 203876 CAATTCTATCAGTAGGTGGTGCAACCGCGTTCAACTGTTGTGCTCAACAGCAACCGCCGA 203935</pre>
|}

=Annotation Changes=
{| border="1" style="border-collapse:collapse; width:90%" cellpadding="6"
! Date !! Affected Features
|-
|2014-11-18
|[https://www.yeastgenome.org/locus/ARS104 ARS104], [https://www.yeastgenome.org/locus/ARS106 ARS106], [https://www.yeastgenome.org/locus/ARS107 ARS107], [https://www.yeastgenome.org/locus/ARS110 ARS110], [https://www.yeastgenome.org/locus/ARS111 ARS111] 
As part of SGD's genome annotation revision R64.2, new ARS consensus sequences were annotated within the following ARS elements on Chromosome I based on Liachko et al. 2013: ARS104, ARS106, ARS107, ARS110, ARS111. 
'''Liachko I, et al.''' (2013) High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast. Genome Res 23(4):698-704. 
[https://www.yeastgenome.org/reference/S000152760 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/23241746 PubMed] | [https://genome.cshlp.org/content/23/4/698 Full-Text] 
|-
|2014-11-18
|[https://www.yeastgenome.org/locus/ARS102 ARS102], [https://www.yeastgenome.org/locus/ARS105 ARS105], [https://www.yeastgenome.org/locus/ARS106 ARS106], [https://www.yeastgenome.org/locus/ARS108 ARS108] 
The chromosomal coordinates of the following ARS elements on Chromosome I were updated based on Liachko et al. 2013 as part of SGD's genome annotation revision R64.2: ARS102, ARS105, ARS106, ARS108. 
'''Liachko I, et al.''' (2013) High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast. Genome Res 23(4):698-704. 
[https://www.yeastgenome.org/reference/S000152760 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/23241746 PubMed] | [https://genome.cshlp.org/content/23/4/698 Full-Text] 
|-
|2014-11-18
|[https://www.yeastgenome.org/locus/YAR061W YAR061W], [https://www.yeastgenome.org/locus/YAR062W YAR062W] 
As part of SGD's genome annotation revision R64.2, the two pseudogenes YAR061W + YAR062W have been combined into a single pseudogene, keeping the name YAR061W. This region is homologous to parts of FLO1/YAR050W and FLO9/YAL063C, but contains stop codons at several positions. 
Teunissen AW and Steensma HY (1995) Review: the dominant flocculation genes of Saccharomyces cerevisiae constitute a new subtelomeric gene family. Yeast 11(11):1001-13
|-
|2007-05-08
|[https://www.yeastgenome.org/locus/snR18 snR18] 
Updated coordinates of snR18 based on GenBank U12981. 
'''Hiraga SI, et al.''' (2012) TFIIIC localizes budding yeast ETC sites to the nuclear periphery. Mol Biol Cell 23(14):2741-54 
[https://www.yeastgenome.org/reference/S000149071 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/22496415 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395662 Full-Text]
|-
|2007-05-08
|[https://www.yeastgenome.org/locus/HRA1 HRA1] 
Updated coordinates of HRA1 based on Yang & Altman 2007. 
'''Yang L and Altman S''' (2007) A noncoding RNA in Saccharomyces cerevisiae is an RNase P substrate. RNA 13(5):682-90 
[https://www.yeastgenome.org/reference/S000121958 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/17379814 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852816 Full-Text]
|-
|2007-03-07
|[https://www.yeastgenome.org/locus/ARS102 ARS102], [https://www.yeastgenome.org/locus/ARS103 ARS103], [https://www.yeastgenome.org/locus/ARS105 ARS105], [https://www.yeastgenome.org/locus/ARS108 ARS108], [https://www.yeastgenome.org/locus/ARS111 ARS111], [https://www.yeastgenome.org/locus/ARS112 ARS112] 
The following ARS elements were added to the genome annotation on Chromosome I based on Xu et al. 2006: ARS102, ARS103, ARS105, ARS108, ARS111, ARS112. 
'''Xu W, et al.''' (2006) Genome-wide mapping of ORC and Mcm2p binding sites on tiling arrays and identification of essential ARS consensus sequences in S. cerevisiae. BMC Genomics 7():276 
[https://www.yeastgenome.org/reference/S000119399 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/17067396 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1657020 Full-Text] 
|-
|2007-03-07
|[https://www.yeastgenome.org/locus/ARS109 ARS109] 
The ACS within ARS101/ARS109 at coordinates 159946-159936 was added based on Xu et al. 2006 and Theis & Newlon 2001. 
'''Theis JF and Newlon CS''' (2001) Two compound replication origins in Saccharomyces cerevisiae contain redundant origin recognition complex binding sites. Mol Cell Biol 21(8):2790-801 
[https://www.yeastgenome.org/reference/S000060218 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/11283258 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC86909 Full-Text] 
'''Xu W, et al.''' (2006) Genome-wide mapping of ORC and Mcm2p binding sites on tiling arrays and identification of essential ARS consensus sequences in S. cerevisiae. BMC Genomics 7():276 
[https://www.yeastgenome.org/reference/S000119399 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/17067396 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1657020 Full-Text] 
|-
|2007-02-06
|[https://www.yeastgenome.org/locus/HRA1 HRA1] 
This RNA gene, HRA1, was described by Samanta et al. (2006). Approximate start and stop coordinates, which are accurate to within 25 nucleotides, have been specified for this non-coding RNA. Many thanks to Manoj Samanta for alerting us to this noncoding RNA. 
'''Samanta MP, et al.''' (2006) Global identification of noncoding RNAs in Saccharomyces cerevisiae by modulating an essential RNA processing pathway. Proc Natl Acad Sci U S A 103(11):4192-7 
[https://www.yeastgenome.org/reference/S000114638 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/16537507 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1389707 Full-Text]
|-
|2006-10-02
|[https://www.yeastgenome.org/locus/ARS109 ARS109] 
An ARS Consensus Sequence (ACS) was added to ARS109 based on Nieduszynski et al. 2006. 
'''Nieduszynski CA, et al.''' (2006) Genome-wide identification of replication origins in yeast by comparative genomics. Genes Dev 20(14):1874-9 
[https://www.yeastgenome.org/reference/S000117321 SGD papers] | [https://www.ncbi.nlm.nih.gov/pubmed/16847347 PubMed Entry] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1522085 Full-Text] | [http://genesdev.cshlp.org/content/20/14/1874/suppl/DC1 Web Supplement]
|-
|2006-09-06
|[https://www.yeastgenome.org/locus/ARS104 ARS104], [https://www.yeastgenome.org/locus/ARS106 ARS106], [https://www.yeastgenome.org/locus/ARS107 ARS107] 
The following ARS elements on Chromosome I were added to SGD based on Nieduszynski et al. 2006: ARS104, ARS106, ARS107. 
'''Nieduszynski CA, et al.''' (2006) Genome-wide identification of replication origins in yeast by comparative genomics. Genes Dev 20(14):1874-9 
[https://www.yeastgenome.org/reference/S000117321 SGD papers] | [https://www.ncbi.nlm.nih.gov/pubmed/16847347 PubMed Entry] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1522085 Full-Text] | [http://genesdev.cshlp.org/content/20/14/1874/suppl/DC1 Web Supplement]
|-
|2006-09-06
|[https://www.yeastgenome.org/locus/ARS109 ARS109], [https://www.yeastgenome.org/locus/ARS110 ARS110] 
Updated coordinates of the following ARS elements on Chromosome I based on Nieduszynski et al. 2006: ARS101/109, ARS110. 
'''Nieduszynski CA, et al.''' (2006) Genome-wide identification of replication origins in yeast by comparative genomics. Genes Dev 20(14):1874-9 
[https://www.yeastgenome.org/reference/S000117321 SGD papers] | [https://www.ncbi.nlm.nih.gov/pubmed/16847347 PubMed Entry] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1522085 Full-Text] | [http://genesdev.cshlp.org/content/20/14/1874/suppl/DC1 Web Supplement]
|-
|2006-05-08
|[https://www.yeastgenome.org/locus/CEN1 CEN1] 
The previously annotated boundaries of CEN1 were adjusted to coincide with the 5' end of CDEI and the 3' end of CDEIII, to more accurately reflect current knowledge regarding centromere structure in Saccharomyces cerevisiae. 
'''Wieland G, et al.''' (2001) Determination of the binding constants of the centromere protein Cbf1 to all 16 centromere DNAs of Saccharomyces cerevisiae. Nucleic Acids Res 29(5):1054-60 
[https://www.yeastgenome.org/reference/S000059647 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/11222754 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC29730 Full-Text] 
'''Espelin CW, et al.''' (2003) Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII. Mol Biol Cell 14(11):4557-68 
[https://www.yeastgenome.org/reference/S000074756 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/13679521 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC266772 Full-Text]
|-
|2006-02-28
|[https://www.yeastgenome.org/locus/ARS110 ARS110] 
This ARS element ARS110 was added to the genome annotation based on Wyrick et al. 2001 and Dimock et al. 1984. 
'''Dimock K, et al.''' (1984) Molecular cloning of the ADE1 gene of Saccharomyces cerevisiae and stability of the transformants. Gene 27(2):233-7 
[https://www.yeastgenome.org/reference/S000040578 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/6373504 PubMed] | [https://www.sciencedirect.com/science/article/pii/0378111984901446?via%3Dihub Full-Text] 
'''Wyrick JJ, et al.''' (2001) Genome-wide distribution of ORC and MCM proteins in S. cerevisiae: high-resolution mapping of replication origins. Science 294(5550):2357-60 
[https://www.yeastgenome.org/reference/S000069019 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/11743203 PubMed] | [https://science.sciencemag.org/content/294/5550/2357 Full-Text] | [http://yfgdb.princeton.edu/cgi-bin/display.cgi?id=11743203&db=pmid YFGdb] | [https://www.ncbi.nlm.nih.gov/pubmed/11743187 Comments & Errata]
|-
|2004-10-18
|[https://www.yeastgenome.org/locus/ARS109 ARS109] 
ARS101 was added to SGD based on Theis and Newlon 2001 and Wyrick et al. 2001. 
Theis JF and Newlon CS (2001) Two compound replication origins in Saccharomyces cerevisiae contain redundant origin recognition complex binding sites. Mol Cell Biol 21(8):2790-801
'''Wyrick JJ, et al.''' (2001) Genome-wide distribution of ORC and MCM proteins in S. cerevisiae: high-resolution mapping of replication origins. Science 294(5550):2357-60 
[https://www.yeastgenome.org/reference/S000069019 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/11743203 PubMed] | [https://science.sciencemag.org/content/294/5550/2357 Full-Text] | [http://yfgdb.princeton.edu/cgi-bin/display.cgi?id=11743203&db=pmid YFGdb] | [https://www.ncbi.nlm.nih.gov/pubmed/11743187 Comments & Errata]
|-
|2004-10-12
|[https://www.yeastgenome.org/locus/CEN1 CEN1] 
Centromeric DNA elements CDEI, CDEII, and CDEIII were annotated based on Wieland et al. 2001 and Espelin et al. 2003. 
'''Wieland G, et al.''' (2001) Determination of the binding constants of the centromere protein Cbf1 to all 16 centromere DNAs of Saccharomyces cerevisiae. Nucleic Acids Res 29(5):1054-60 
[https://www.yeastgenome.org/reference/S000059647 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/11222754 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC29730 Full-Text] 
'''Espelin CW, et al.''' (2003) Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII. Mol Biol Cell 14(11):4557-68 
[https://www.yeastgenome.org/reference/S000074756 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/13679521 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC266772 Full-Text]
|-
|2003-09-22
|[https://www.yeastgenome.org/locus/YAL044C YAL044C] 
The start site of GCV3/YAL044C was moved 21 nt (7 codons) downstream, based on the automated comparison of closely-related Saccharomyces species by Kellis et al. 2003. The numbering for both the nucleotides in the DNA coding sequence and the amino acids in the predicted protein have been updated. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine. 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54 Errata] 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 
|-
|2003-09-22
|[https://www.yeastgenome.org/locus/YAL034C YAL034C] 
The start site of FUN19/YAL034C was moved 150 nt (50 codons) downstream, based on the automated comparison of closely-related Saccharomyces species by Kellis et al. 2003. The numbering for both the nucleotides in the DNA coding sequence and the amino acids in the predicted protein have been updated. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine. 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54 Errata] 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 
|-
|2003-09-22
|[https://www.yeastgenome.org/locus/YAL011W YAL011W] 
The start site of YAL011W was moved 39 nt (13 codons) downstream, based on the automated comparison of closely-related Saccharomyces species by Kellis et al. 2003. The numbering for both the nucleotides in the DNA coding sequence and the amino acids in the predicted protein have been updated. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine. 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54 Errata] 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 
|-
|2003-09-09
|[https://www.yeastgenome.org/locus/TEL01L TEL01L], [https://www.yeastgenome.org/locus/TEL01R TEL01R] 
The chromosomal locations for the following telomeric features on Chromosome I were generously provided by Ed Louis and Dave Barton (University of Leicester, UK): TEL01L, TEL01L-TR, TEL01L-XC, TEL01L-XR, TEL01R, TEL01R-TR, and TEL01R-XC. 
|-
|2003-07-29
|[https://www.yeastgenome.org/locus/YAL016C-B YAL016C-B] 
Thanks to Kessler et al. 2003 for providing the coordinates of ORF YAL016C-B on Chromosome I. 
'''Kessler MM, et al.''' (2003) Systematic discovery of new genes in the Saccharomyces cerevisiae genome. Genome Res 13(2):264-71. 
[https://www.yeastgenome.org/reference/S000073671 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12566404 PubMed] | [https://genome.cshlp.org/content/13/2/264.long Full-Text] 
|-
|2003-07-29
|[https://www.yeastgenome.org/locus/YAL037C-B YAL037C-B], [https://www.yeastgenome.org/locus/YAL067W-A YAL067W-A], [https://www.yeastgenome.org/locus/YAL068W-A YAL068W-A], [https://www.yeastgenome.org/locus/YAR035C-A YAR035C-A] 
Thanks to Kumar et al. 2002 for providing the coordinates of the following ORFs on Chromosome I: YAL037C-B, YAL067W-A, YAL068W-A, YAR035C-A. 
'''Kumar A, et al.''' (2002) An integrated approach for finding overlooked genes in yeast. Nat Biotechnol 20(1):58-63. 
[https://www.yeastgenome.org/reference/S000073673 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/11753363 PubMed] | [https://www.nature.com/articles/nbt0102-58 Full-Text] | [http://yfgdb.princeton.edu/cgi-bin/display.cgi?id=11753363&db=pmid YFGdb] | [https://www.yeastgenome.org/reference/S000141796 Comments & Errata] 
|-
|2003-07-29
|[https://www.yeastgenome.org/locus/YAL016C-A YAL016C-A], [https://www.yeastgenome.org/locus/YAL019W-A YAL019W-A], [https://www.yeastgenome.org/locus/YAL026C-A YAL026C-A], [https://www.yeastgenome.org/locus/YAL031W-A YAL031W-A], [https://www.yeastgenome.org/locus/YAL037C-A YAL037C-A], [https://www.yeastgenome.org/locus/YAL047W-A YAL047W-A], [https://www.yeastgenome.org/locus/YAL059C-A YAL059C-A], [https://www.yeastgenome.org/locus/YAR019W-A YAR019W-A] 
Thanks to MIPS for providing the coordinates of the following ORFs on Chromosome I: YAL016C-A, YAL019W-A, YAL026C-A, YAL031W-A, YAL037C-A, YAL047W-A, YAL059C-A, and YAR019W-A. 
|-
|2003-07-29
|[https://www.yeastgenome.org/locus/YAL063C-A YAL063C-A] 
Thanks to Oshiro et al., Velculescu et al., and Basrai et al. for providing the coordinates of ORF YAL063C-A on Chromosome I. 
'''Basrai MA, et al.''' (1999) NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae. Mol Cell Biol 19(10):7041-9 
[https://www.yeastgenome.org/reference/S000042214 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/10490641 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC84699 Full-Text] 
'''Velculescu VE, et al.''' (1997) Characterization of the yeast transcriptome. Cell 88(2):243-51. 
[https://www.yeastgenome.org/reference/S000058021 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/9008165 PubMed] | [https://www.sciencedirect.com/science/article/pii/S0092867400818450?via%3Dihub Full-Text] | [http://yfgdb.princeton.edu/cgi-bin/display.cgi?id=9008165&db=pmid YFGdb] 
'''Oshiro G, et al.''' (2002) Parallel identification of new genes in Saccharomyces cerevisiae. Genome Res 12(8):1210-20. 
[https://www.yeastgenome.org/reference/S000073672 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12176929 PubMed] | [https://genome.cshlp.org/content/12/8/1210.long Full-Text] | [https://genome.cshlp.org/content/12/8/1210/suppl/DC1 Web Supplement] | [http://yfgdb.princeton.edu/cgi-bin/display.cgi?id=12176929&db=pmid YFGdb] 
|-
|2001-01-30
|[https://www.yeastgenome.org/locus/YAL044W-A YAL044W-A] 
ORF added based on similarity to an S. pombe gene (information submitted by Valerie Wood). 
|-
|1999-07-17
|[https://www.yeastgenome.org/locus/YAR043C YAR043C], [https://www.yeastgenome.org/locus/YAR052C YAR052C], [https://www.yeastgenome.org/locus/YAR074C YAR074C] 
Deleted ORF, does not encode a protein; this putative ORF was included in the original annotation of Chromosome I but was later withdrawn 
|}

Chromosome II History

2019-10-02T21:33:50Z

Pcng: /* Annotation Changes without sequence changes */

This page lists all sequence and annotation changes that have been made to the Chromosome II systematic reference sequence since its intial release on 1996-07-31. 
*The sequence of Chromosome II has been updated '''192''' times, affecting '''122''' features. 
*The annotation of Chromosome II has been updated '''49''' times, affecting '''88''' features. 
Current and past versions can be obtained from SGD's [https://www.yeastgenome.org/downloads Download site].

__FORCETOC__

=Sequence Changes=

{|border="1" style="border-collapse:collapse; width:90%" cellpadding="6"
! Date !! Affected Features !! Start Coordinate of Change !! End Coordinate of Change !! Type of Change !! Old Sequence !! New Sequence
|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBR068C YBR068C]
| 375081
| 375081
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 375272
| 375272
| Substitution
| T
| A
|- style="height:30px; width:30px; text-align:center;"
| 374011
| 374011
| Substitution
| T
| A
|-
| || colspan="6" | Nucleotide substitutions within the coding region of BAP2/YBR068C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 139 is now Valine rather than Glutamic Acid, and residue 203 is now Tryptophan rather than Glycine.
<pre>New 373969 GAAGTCAAGGTCAATCTTGTCGAGGGGATTTAATAGCGTAAAATCACGGTTGTAAACCAT 374028
||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||
Old 373966 GAAGTCAAGGTCAATCTTGTCGAGGGGATTTAATAGCGTAAAATCTCGGTTGTAAACCAT 374025
New 375049 AAGAATATAAATGTCCGGATTTATTTTATCATTCCAAAATTGAATAGTCATAGACGCGGT 375108
||||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||
Old 375046 AAGAATATAAATGTCCGGATTTATTTTATCATTCCCAAATTGAATAGTCATAGACGCGGT 375105
New 375229 ATAGGTTACCGCCATCTCACCTGCAGCTTGGATCATGAAGTACGTCACGAAAGAAACCAA 375288
|||||||||||||||||||||||||||||||||||||||||||||| |||||||||||||
Old 375226 ATAGGTTACCGCCATCTCACCTGCAGCTTGGATCATGAAGTACGTCTCGAAAGAAACCAA 375285</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR097W YBR097W]
| 439496
| 439496
| Substitution
| T
| G
|- style="height:30px; width:30px; text-align:center;"
| 437344
| 437344
| Substitution
| A
| G
|-
| || colspan="6" | Nucleotide change(s) in the coding region of VPS15/YBR097W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 134 is now Alanine rather than Threonine, and residue 851 is now Arginine rather than Isoleucine.
<pre>New 437325 ATTCATTGCTTTCCAGTTGTTAAATGCATTAAAGGACATTCATAATCTGAATATTGTCCA 437384
||||||||||||||||||||||||| ||||||||||||||||||||||||||||||||||
Old 437319 ATTCATTGCTTTCCAGTTGTTAAATACATTAAAGGACATTCATAATCTGAATATTGTCCA 437378
New 439485 CTTAACTGCTGAAGACAGAAATTGGATTGATAAGTTCCACATTATTGGGCTAACAGAAAA 439544
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 439479 CTTAACTGCTGAAGACATAAATTGGATTGATAAGTTCCACATTATTGGGCTAACAGAAAA 439538</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR045C YBR045C]
| 328382
| 328382
| Insertion
| || T
|-
| || colspan="6" | A single nucleotide was inserted within ORF GIP1/YBR045C, altering its coding sequence. The start, stop, and majority of the reading frame remain the same, but the C-terminus has changed and the annotated protein is now 66 amino acids longer.
<pre>New 328369 CTCAGTCTATAATTTTCTGCTTCATTTCTCTGCCTTTTATACTCTGTATATTGAAAATAA 328428
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Old 328368 CTCAGTCTATAATTT-CTGCTTCATTTCTCTGCCTTTTATACTCTGTATATTGAAAATAA 328426</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR044C YBR044C]
| 324366
| 324366
| Insertion
|
| T
|-
| || colspan="6" | One nucleotide was inserted within ORF TCM62/YBR044C, very near its 3' end, altering its coding sequence. The start, stop, and majority of reading frame remain the same, but the C-terminus is different and the annotated protein sequence is now one amino acid shorter.
<pre>New 324349 TGTGCCGTTCAGGCTTTTTGTATACACATGTGATAATTGTATTACAGCTTGTAAGTAATT 324408
|||||||||||||||||| |||||||||||||||||||||||||||||||||||||||||
Old 324349 TGTGCCGTTCAGGCTTTT-GTATACACATGTGATAATTGTATTACAGCTTGTAAGTAATT 324407</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR007C YBR007C]
| 250403
| 250403
| Substitution
| C
| G
|- style="height:30px; width:30px; text-align:center;"
| 250039
| 250039
| Substitution
| T
| G
|-
| || colspan="6" | Two nucleotide substitutions within the coding region of DSF2/YBR007C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 205 is now Serine rather than Arginine, and residue 327 is now Proline rather than Threonine.
<pre>New 250012 AGACCGTTTAGGAGATGGTTTGATGGGTGTTGTATCACTCTTAGTTAACTTGAGTTTGGA 250071
|||||||||||||||||||||||||| |||||||||||||||||||||||||||||||||
Old 250013 AGACCGTTTAGGAGATGGTTTGATGGTTGTTGTATCACTCTTAGTTAACTTGAGTTTGGA 250072
New 250372 CCTATATTTCTCGAAGTTGAAAGGATTAGGGCTATTTGTGCTTCTATTGCCATTTTCAAG 250431
|||||||||||||||||||||||||||||| |||||||||||||||||||||||||||||
Old 250373 CCTATATTTCTCGAAGTTGAAAGGATTAGGCCTATTTGTGCTTCTATTGCCATTTTCAAG 250432</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBL105C YBL105C]
| 17455
| 17455
| Substitution
| A
| C
|- style="height:30px; width:30px; text-align:center;"
| 15835
| 15835
| Substitution
| T
| C
|- style="height:30px; width:30px; text-align:center;"
| 15332
| 15332
| Substitution
| G
| C
|-
| || colspan="6" | The substitution of three nucleotides within the coding region of PKC1/YBL105C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 81 is now Cysteine rather than Phenylalanine, residue 621 is now Arginine rather than Lysine, and residue 789 is now Alanine rather than Proline.
<pre>New 15301 TGCGGAGATTGTTGATCAGTGGTTCTGGAGGCATGAGTACTTGTAGGAGCCAAGGACACT 15360
||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||||
Old 15301 TGCGGAGATTGTTGATCAGTGGTTCTGGAGGGATGAGTACTTGTAGGAGCCAAGGACACT 15360
New 15791 TAAATTTATTTAGTTTCTCACGCCCGTGCGTTTGTAGTGAAATTCTTTTATCAATAATAG 15850
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 15791 TAAATTTATTTAGTTTCTCACGCCCGTGCGTTTGTAGTGAAATTTTTTTATCAATAATAG 15840
New 17411 CATTTGGCGATTTGGTAGAAAGAAACCCGTATTCCTTCGAATTGCATCGCTCATTATCTT 17470
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 17411 CATTTGGCGATTTGGTAGAAAGAAACCCGTATTCCTTCGAATTGAATCGCTCATTATCTT 17470</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL057C YBL057C]
| 113437
| 113437
| Deletion
| G
|
|-
| || colspan="6" | One nucleotide was deleted within ORF PTH2/YBL057C, near its 5' end, altering its coding sequence. The stop and reading frame remain the same, but the start has been moved 18 nucleotides downstream and the annotated protein sequence is now six amino acids shorter.
<pre>New 113393 ATGGTGTAATTCGAAGAAACTGTCATCTTTTCCATTAAAAAG-ACGTTATCATGTTACTC 113451
|||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 113395 ATGGTGTAATTCGAAGAAACTGTCATCTTTTCCATTAAAAAGGACGTTATCATGTTACTC 113454</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBL068W YBL068W]
| 92918
| 92920
| Deletion
| CCG
|
|- style="height:30px; width:30px; text-align:center;"
| 92916
| 92916
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 92679
| 92679
| Substitution
| C
| A
|-
| || colspan="6" | Two nucleotide substitutions and one trinucleotide deletion were made within the ORF PRS4/YBL068W, altering its coding sequence. The start, stop, and reading frame remain the same, but the annotated protein is now one amino acid shorter.
<pre>New 92637 TTAATGATTTCTTGATGGAATTATTAATTTTAATTCATGCTTGCAAAATTGCATCTGCAA 92696
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 92635 TTAATGATTTCTTGATGGAATTATTAATTTTAATTCATGCTTGCCAAATTGCATCTGCAA 92694
New 92877 ACAACCTATATGCAGAACCAAGTGTTTTAAATTATATTAGAAC---GAAAACAGATTTCG 92933
||||||||||||||||||||||||||||||||||||||||| | ||||||||||||||
Old 92875 ACAACCTATATGCAGAACCAAGTGTTTTAAATTATATTAGAGCCCGGAAAACAGATTTCG 92934</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR078W YBR078W]
| 394727
| 394727
| Insertion
|
| C
|-
| || colspan="6" | One nucleotide was inserted within ORF ECM33/YBR078W, very near its 3' end, altering its coding sequence. The start, stop, and vast majority of reading frame remain the same, but the C-terminus is different and the annotated protein sequence is now 39 amino acids shorter.
<pre>New 394715 TGCTGCTGTTGGCGTTGCCTTACTATAAGATTAAAGCAACAATTTGTGTTTCTATTATTA 394774
|||||||||||||||||| |||||||||||||||||||||||||||||||||||||||||
Old 394710 TGCTGCTGTTGGCGTTGC-TTACTATAAGATTAAAGCAACAATTTGTGTTTCTATTATTA 394768</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR076W YBR076W]
| 391277
| 391277
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 390442
| 390442
| Deletion
| G
|
|-
| || colspan="6" | A single G nucleotide was deleted near the 3' end, and a single A nucleotide was inserted near the 5' end of ORF ECM8/YBR076W, altering its coding sequence. The ORF was extended 49 amino acids at the N-terminus and shortened 34 amino acids at the C-terminus, resulting in a protein that is 15 amino acids larger. Although this protein is altered at both ends, the central portion of the protein remains the same.
<pre>New 390408 AAACCATCAAGAACAAAATATTCCCACAAAGGAAAATATT-CAACGATAGCGAAAATTTT 390466
|||||||||||||||||||||||||||||||||||||||| |||||||||||||||||||
Old 390402 AAACCATCAAGAACAAAATATTCCCACAAAGGAAAATATTGCAACGATAGCGAAAATTTT 390461
New 391247 CGAACGAAATGTTTATATGTCCAAGTTATAACAAAAAGCAATTGATTGTGTACGCAAGAT 391306
|||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
Old 391242 CGAACGAAATGTTTATATGTCCAAGTTATAACAAAA-GCAATTGATTGTGTACGCAAGAT 391300</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR137W YBR137W]
| 513365
| 513365
| Substitution
| A
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of YBR137W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 110 is now Glycine rather than Serine.
<pre>New 513345 CAAGTTTCTATATGGGCTGCAAGAAAGGTGACAAAACACCGGAGGAAAAGTTTTTTGTGG 513404
|||||||||||||||||||||||||| |||||||||||||||||||||||||||||||||
Old 513339 CAAGTTTCTATATGGGCTGCAAGAAAAGTGACAAAACACCGGAGGAAAAGTTTTTTGTGG 513398</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR121C YBR121C]
| 481671
| 481675
| Substitution
| TGATG
| GTAGT
|-
| || colspan="6" | Nucleotide substitutions within the coding region of GRS1/YBR121C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 563-564 are now TT rather than HH.
<pre>New 481665 TTGGCGACTTCAGTAGTAACAGGAACTAAATCTTTGTGGTTAGATAAAGGAACTAAAAGA 481724
|||||||||||| | |||||||||||||||||||||||||||||||||||||||||||
Old 481659 TTGGCGACTTCATGATGAACAGGAACTAAATCTTTGTGGTTAGATAAAGGAACTAAAAGA 481718</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR108W YBR108W]
| 456359
| 456359
| Substitution
| C
| T
|-
| || colspan="6" | A single nucleotide substitution within the coding region of AIM3/YBR108W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 515 is now Valine rather than Alanine.
<pre>New 456345 AGGACATTATGATGTAGATGTCAACATCATGCCACCTCCAAAACCTTTCAGACATGGACT 456404
|||||||||||||||||||| |||||||||||||||||||||||||||||||||||||||
Old 456339 AGGACATTATGATGTAGATGCCAACATCATGCCACCTCCAAAACCTTTCAGACATGGACT 456398</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR295W YBR295W]
| 793986
| 793987
| Substitution
| AC
| CA
|-
| || colspan="6" | Nucleotide substitutions within the coding region of PCA1/YBR295W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 382 is now Histidine rather than Threonine.
<pre>New 793961 GGATTGTGCTGTTACCTCAACTATTTCTGGACACTCTTCGAGTGAAATTTCAAGAATCGT 794020
||||||||||||||||||||||||||||||| |||||||||||||||||||||||||||
Old 793955 GGATTGTGCTGTTACCTCAACTATTTCTGGAACCTCTTCGAGTGAAATTTCAAGAATCGT 794014</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR289W YBR289W]
| 781354
| 781354
| Substitution
| G
| C
|- style="height:30px; width:30px; text-align:center;"
| 780541
| 780541
| Substitution
| C
| A
|-
| || colspan="6" | Two nucleotide substitutions within the coding region of SNF5/YBR289W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 564 is now Aspartic Acid rather than Glutamic Acid.
<pre>New 780521 ACAACCTCCCACCAATGTTCAGCCAACTATTGGCCAACTTCCTCAACTTCCAAAATTAAA 780580
|||||||||||||||||||||||| |||||||||||||||||||||||||||||||||||
Old 780517 ACAACCTCCCACCAATGTTCAGCCCACTATTGGCCAACTTCCTCAACTTCCAAAATTAAA 780576
New 781311 GATATTGTCGTGGGACAAAACCAGTTAATCGATCAATTTGAGTGGGACATCTCTAATAGT 781370
||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
Old 781307 GATATTGTCGTGGGACAAAACCAGTTAATCGATCAATTTGAGTGGGAGATCTCTAATAGT 781366</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR288C YBR288C]
| 779354
| 779356
| Substitution
| TAC
| ACT
|-
| || colspan="6" | Nucleotide substitutions within the coding region of APM3/YBR288C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 35-36 are now QS rather than RT.
<pre>New 779321 TCACTACTGCTATCTTCGAGCAATTGAGGACATGTGGACTGAACGCGGGTCCACAGGTGC 779380
||||||||||||||||||||||||||||||||||||| ||||||||||||||||||||
Old 779317 TCACTACTGCTATCTTCGAGCAATTGAGGACATGTGGTACGAACGCGGGTCCACAGGTGC 779376</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBL099W YBL099W]
| 38210
| 38210
| Substitution
| A
| T
|- style="height:30px; width:30px; text-align:center;"
| 38067
| 38067
| Substitution
| C
| T
|-
| || colspan="6" | The substitution of 2 nucleotides within the coding region of ATP1/YBL099W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 340 is now Serine rather than Proline.
<pre>New 38039 AGCCTACCCTGGTGATGTCTTTTACTTGCATTCAAGATTGCTAGAAAGAGCCGCTAAGCT 38098
||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||||
Old 38036 AGCCTACCCTGGTGATGTCTTTTACTTGCATCCAAGATTGCTAGAAAGAGCCGCTAAGCT 38095
New 38169 GCTTATATTCCAACCAATGTTATTTCCATTACCGATGGTCAAATTTTCTTGGAAGCTGAA 38228
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 38166 GCTTATATTCCAACCAATGTTATTTCCATTACCGATGGTCAAATATTCTTGGAAGCTGAA 38225</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL097W YBL097W]
| 42377
| 42377
| Substitution
| C
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of BRN1/YBL097W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 517 is now Glycine rather than Alanine.
<pre>New 42359 CAAGATTGTTCATTAAACCGGGGCAGAAAATGAGTCTGTTCAGTCATAGGAAGCATACCA 42418
||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||
Old 42356 CAAGATTGTTCATTAAACCGGCGCAGAAAATGAGTCTGTTCAGTCATAGGAAGCATACCA 42415</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL091C YBL091C]
| 48369
| 48369
| Substitution
| A
| T
|-
| || colspan="6" | A single nucleotide substitution within the coding region of MAP2/YBL091C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 86 is now Aspartic Acid rather than Valine.
<pre>New 48359 ACGTGATTCTTCATCCGTGGTTCTTTGCAGATTGAAATCTTGATGATAGTCCATCCACGC 48418
||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||
Old 48356 ACGTGATTCTTCAACCGTGGTTCTTTGCAGATTGAAATCTTGATGATAGTCCATCCACGC 48415</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL088C YBL088C]
| 55145
| 55145
| Substitution
| A
| C
|-
| || colspan="6" | A single nucleotide substitution within the coding region of TEL1/YBL088C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 1412 is now Cysteine rather than Phenylalanine.
<pre>New 55139 GCATCAAGGCAGTATTTCCAAGTTTTTATTTTGATGAGATCCCGATGCTCTAAAAGCTTT 55198
||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||||
Old 55136 GCATCAAGGAAGTATTTCCAAGTTTTTATTTTGATGAGATCCCGATGCTCTAAAAGCTTT 55195</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL084C YBL084C]
| 68154
| 68155
| Substitution
| TG
| GA
|-
| || colspan="6" | The substitution of two nucleotides within the coding region of CDC27/YBL084C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 430 is now Serine rather than Glutamine.
<pre>New 68108 CGACCTTAATATTAAAGCGAAATTATACATGATTTCAGGCAGCGTAATTGAATAATCACT 68167
||||||||||||||||||||||||||||||||||||||||||||||||| |||||||||
Old 68105 CGACCTTAATATTAAAGCGAAATTATACATGATTTCAGGCAGCGTAATTTGATAATCACT 68164</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR275C YBR275C]
| 754908
| 754908
| Substitution
| T
| C
|-
| || colspan="6" | A single nucleotide substitution within the coding region of RIF1/YBR275C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 732 is now Alanine rather than Threonine.
<pre>New 754902 TACTTCAACAGCCTGGAACACAACTTTCATGATTTTATCGTATTCACGCTTGATGATCTG 754961
||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||
Old 754897 TACTTCAACAGTCTGGAACACAACTTTCATGATTTTATCGTATTCACGCTTGATGATCTG 754956</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR270C YBR270C]
| 743936
| 743938
| Substitution
| GCC
| CCG
|-
| || colspan="6" | Nucleotide substitutions within the coding region of BIT2/YBR270C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 152-153 are now SG rather than RA.
<pre>New 743922 AGTGCCGTAGTTTTTTGACCCGCTCCTGCTTCGATTTCTCATATTATCTTTTGAATTGGT 743981
||||||||||||||||||| | ||||||||||||||||||||||||||||||||||||||
Old 743917 AGTGCCGTAGTTTTTTGACGCCCTCCTGCTTCGATTTCTCATATTATCTTTTGAATTGGT 743976</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR266C YBR266C], [https://www.yeastgenome.org/locus/YBR267W YBR267W]
| 740291
| 740292
| Substitution
| CG
| GC
|-
| || colspan="6" | Nucleotide substitutions within the coding regions of overlapping genes REI1/YBR267W and SLM6/YBR266C resulted in altered sequences for both proteins. The start, stop, and reading frames of both proteins remain the same, but protein residues 152-153 of REI1/YBR267W are now KL rather than NV, and protein residue 31 of SLM6/YBR266C is now Serine rather than Threonine.
<pre>New 740262 AGGAAGAAATGGCGGAAAGAGTAATGCAAGAAAAGCTACGCAACAGAGTCGATATTCCAC 740321
|||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||
Old 740257 AGGAAGAAATGGCGGAAAGAGTAATGCAAGAAAACGTACGCAACAGAGTCGATATTCCAC 740316</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR265W YBR265W]
| 739341
| 739341
| Substitution
| A
| T
|-
| || colspan="6" | A single nucleotide substitution within the coding region of TSC10/YBR265W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 255 is now Aspartic Acid rather than Glutamic Acid.
<pre>New 739302 CAAGCATGTGATATCATTGCCAAGTCGCTGGCCAGAGGTGATGATGACGTTTTTACAGAT 739361
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 739297 CAAGCATGTGATATCATTGCCAAGTCGCTGGCCAGAGGTGATGAAGACGTTTTTACAGAT 739356</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR094W YBR094W]
| 433377
| 433378
| Substitution
| CG
| GC
|- style="height:30px; width:30px; text-align:center;"
| 432380
| 432380
| Substitution
| T
| C
|-
| || colspan="6" | Nucleotide changes within the coding region of PBY1/YBR094W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 450 is now Alanine rather than Arginine.
<pre>New 432345 GAGTGGATATTAATCGATGGAACTCCAGCATCGTGCGCAAACATCGGGCTGCACCTATTG 432404
||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||||
Old 432339 GAGTGGATATTAATCGATGGAACTCCAGCATCGTGCGCAAATATCGGGCTGCACCTATTG 432398
New 433365 ACTATTGATTTAGATTATGCTGAATTTCTAGACGACGCATTAGATGAAAATTGGGAATTA 433424
|||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||
Old 433359 ACTATTGATTTAGATTATCGTGAATTTCTAGACGACGCATTAGATGAAAATTGGGAATTA 433418</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR089C-A YBR089C-A]
| 426394
| 426396
| Substitution
| CCG
| GCC
|-
| || colspan="6" | Nucleotide substitutions within the coding region of NHP6B/YBR089C-A resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 30 is now Glycine rather than Arginine.
<pre>New 426355 GACAATGTCTCTGTTTTCATTAGCAAAGAACATATAAGCTGACAAGCCCCTCTTAGGGGC 426414
||||||||||||||||||||||||||||||||||||||||||||| | ||||||||||||
Old 426349 GACAATGTCTCTGTTTTCATTAGCAAAGAACATATAAGCTGACAACCGCCTCTTAGGGGC 426408</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBL056W YBL056W]
| 114870
| 114870
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 114868
| 114868
| Substitution
| G
| A
|-
| || colspan="6" | Two nucleotide substitutions within the coding region of PTC3/YBL056W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 369 is now Glycine rather than Aspartic Acid.
<pre>New 114832 CGACATGGAAATTGATGATCTTGATACCGAATTAGGCAGCAGTGCTACTCCCTCAAAGTT 114891
||||||||||||||||||||||||||||||||| | ||||||||||||||||||||||||
Old 114835 CGACATGGAAATTGATGATCTTGATACCGAATTGGACAGCAGTGCTACTCCCTCAAAGTT 114894</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="10"| 2011-02-03
| rowspan="10"| [https://www.yeastgenome.org/locus/YBR207W YBR207W]
| 636336
| 636336
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 636319
| 636322
| Substitution
| GCTT
| ACTG
|- style="height:30px; width:30px; text-align:center;"
| 636306
| 636309
| Substitution
| AATA
| TATG
|- style="height:30px; width:30px; text-align:center;"
| 636141
| 636141
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 635890
| 635890
| Deletion
| A
|
|- style="height:30px; width:30px; text-align:center;"
| 635882
| 635882
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 635247
| 635247
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 635192
| 635192
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 636342
| 636342
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 635822
| 635822
| Substitution
| C
| G
|-
| || colspan="6" | Nucleotide changes within the coding region of FTH1/YBR207W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 18 is now Glu rather than Lys, residue 36 is now Gly rather than Asp, residue 228 is now Glu rather than Gln, residues 249-250 are now VF rather than YS, residue 334 is now Gly rather than Glu, residues 389-390 are now IC rather than KY, and residues 399-401 are now EKY rather than GKC.
<pre>New 635196 GGAATCCTTAGAAATTGTTGTCATTGTTTCTATCCTGTTGACGATCGTCAAACAAGGTCT 635255
| |||||||||||||||||||||||||||||||||||||||||||||||||||||| |||
Old 635191 GAAATCCTTAGAAATTGTTGTCATTGTTTCTATCCTGTTGACGATCGTCAAACAAGATCT 635250
New 635803 ACCCAAAAAGGTGTGAAATTCAGTGAAAAGTACTCCTTCTTCATATTACCATTTATAACG 635862
|||||||||||||||||||||||| |||||||||||||||||||||||||||||||||||
Old 635798 ACCCAAAAAGGTGTGAAATTCAGTCAAAAGTACTCCTTCTTCATATTACCATTTATAACG 635857
New 635863 ACTTTGAGAGAAGGGTTAGAAGCTGTTGTATTC-ATTGGAGGTATCGGTATTGACCAACC 635921
||||||||||||||||||||||||| ||||||| ||||||||||||||||||||||||||
Old 635858 ACTTTGAGAGAAGGGTTAGAAGCTG-TGTATTCAATTGGAGGTATCGGTATTGACCAACC 635916
New 636102 AGACTACGTCAACAAATGTAACGGTCAAGACATGAGTGAAGTAGGAAATGGACCCGGTTC 636161
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 636097 AGACTACGTCAACAAATGTAACGGTCAAGACATGAGTGAAGTAGAAAATGGACCCGGTTC 636156
New 636292 GCCTACTGGTTGGTATTAATATGCGCTTTGAAACTGCTAATGATAGAAGAAAAATACGGA 636351
||||||||||||||||||| || ||||||||| || ||||||||||||| ||||| ||||
Old 636287 GCCTACTGGTTGGTATTAAAATACGCTTTGAAGCTTCTAATGATAGAAGGAAAATGCGGA 636346</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL014C YBL014C]
| 201635
| 201635
| Substitution
| G
| C
|-
| || colspan="6" | A single nucleotide substitution within the coding region of RRN6/YBL014C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 39 is now Lysine rather than Asparagine.
<pre>New 201592 CCTCGGCCAATGTATCATCTACTGGTCTTAGCCATTGTGGCTTTTCTTGCTTCTTCGTAG 201651
|||||||||||||||||||||||||||||||||||||||| |||||||||||||||||||
Old 201595 CCTCGGCCAATGTATCATCTACTGGTCTTAGCCATTGTGGGTTTTCTTGCTTCTTCGTAG 201654</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL008W YBL008W]
| 210433
| 210433
| Substitution
| A
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of HIR1/YBL008W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 260 is now Valine rather than Methionine.
<pre>New 210412 AATGGGCCCGTAAGTTCTGTGGCAATTGTAAATAGAGGAACTTGGGATACAAATGTTAGT 210471
|||||||||||||||||| |||||||||||||||||||||||||||||||||||||||||
Old 210415 AATGGGCCCGTAAGTTCTATGGCAATTGTAAATAGAGGAACTTGGGATACAAATGTTAGT 210474</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR043C YBR043C]
| 323835
| 323836
| Substitution
| CG
| GC
|-
| || colspan="6" | Nucleotide substitutions within the coding region of QDR3/YBR043C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 37 is now Serine rather than Threonine.
<pre>Query 323809 CTATAATCGTTGTGCTCGCTGTGCGGGCTGCCGCTGCTTTCATCGCAGTGCATCATAACA 323868
|||||||||||||||||||||||||| ||||||||||||||||||||||||||||||||
Sbjct 323809 CTATAATCGTTGTGCTCGCTGTGCGGCGTGCCGCTGCTTTCATCGCAGTGCATCATAACA 323868</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR141C YBR141C]
| 527099
| 527099
| Substitution
| A
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of YBR141C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 312 is now Proline rather than Serine.
<pre>New 527085 AAAGCTACTCGGCTGCGGTGGAACTACCTGCAATTGATACAAACAATAGTACAACTTATT 527144
|||||||||||||||||||| |||||||||||||||||||||||||||||||||||||||
Old 527079 AAAGCTACTCGGCTGCGGTGAAACTACCTGCAATTGATACAAACAATAGTACAACTTATT 527138</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR138C YBR138C]
| 514965
| 514966
| Substitution
| AC
| CA
|-
| || colspan="6" | Nucleotide substitutions within the coding region of YBR138C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 122 is now Leucine rather than Cysteine.
<pre>New 514955 TAGGCTTGGCACCTATCAATTGTGAGCGACGCTTTCTTACATTCAATAACTGTTGGTTCT 515014
|||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 514949 TAGGCTTGGCACCTATACATTGTGAGCGACGCTTTCTTACATTCAATAACTGTTGGTTCT 515008</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR004C YBR004C]
| 245111
| 245111
| Substitution
| T
| A
|-
| || colspan="6" | A single nucleotide substitution within the coding region of GPI18/YBR004C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 187 is now Serine rather than Threonine.
<pre>New 245092 TACGGGCACGGAAATGGAGCATTCACGACTCCAAATACCAACAAATGCAAAAAAAAAAGA 245151
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 245094 TACGGGCACGGAAATGGTGCATTCACGACTCCAAATACCAACAAATGCAAAAAAAAAAGA 245153</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="8"| 2011-02-03
| rowspan="8"| [https://www.yeastgenome.org/locus/YBL106C YBL106C]
| 13553
| 13553
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 13492
| 13492
| Substitution
| A
| T
|- style="height:30px; width:30px; text-align:center;"
| 13477
| 13477
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 13102
| 13102
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 11379
| 11379
| Substitution
| A
| C
|- style="height:30px; width:30px; text-align:center;"
| 11345
| 11345
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 11308
| 11309
| Substitution
| AA
| TT
|- style="height:30px; width:30px; text-align:center;"
| 11053
| 11053
| Substitution
| T
| C
|-
| || colspan="6" | Several nucleotide substitutions within the coding region of SRO77/YBL106C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 130 is now Isoleucine rather than Phenylalanine, residue 135 is now Serine rather than Proline, residue 260 is now Serine rather than Alanine, residue 834 is now Glycine rather than Valine, residue 858 is now Threonine rather than Serine, and 943 is now Glutamic Acid rather than Lysine.
<pre>New 11041 ACCTGTGATCTTCCGTACCGGGAGGTAACTTTCTGGCTGCATTACTACTACTGGAAGATA 11100
|||||||||||| |||||||||||||||||||||||||||||||||||||||||||||||
Old 11041 ACCTGTGATCTTTCGTACCGGGAGGTAACTTTCTGGCTGCATTACTACTACTGGAAGATA 11100
New 11281 GTTGTGATATGTCAGCAGTATGATTCGTTCCGGTGGCACTTTCATTAAGTACTGAAATCA 11340
||||||||||||||||||||||||||| |||||||||||||||||||||||||||||||
Old 11281 GTTGTGATATGTCAGCAGTATGATTCGAACCGGTGGCACTTTCATTAAGTACTGAAATCA 11340
New 11341 AAGAGGCTTGGAATTTCCCTGTGCGAATGACAATGTCACCATTTTCTAATATAGATGAAT 11400
|||| ||||||||||||||||||||||||||||||||| |||||||||||||||||||||
Old 11341 AAGAAGCTTGGAATTTCCCTGTGCGAATGACAATGTCAACATTTTCTAATATAGATGAAT 11400
New 13081 TGACATCCCAAAATACCAAGGAATTATCTTCATGGACAGTTAATATATGTAAGGAATTTG 13140
||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||
Old 13081 TGACATCCCAAAATACCAAGGCATTATCTTCATGGACAGTTAATATATGTAAGGAATTTG 13140
New 13441 ATCCACTCTCGAGGCCAATCAGCATCCAATCCAAGGACGGATCAGTCTCAATACAAGTGA 13500
|||||||||||||||||||||||||||||||||||| |||||||||||||| ||||||||
Old 13441 ATCCACTCTCGAGGCCAATCAGCATCCAATCCAAGGGCGGATCAGTCTCAAAACAAGTGA 13500
New 13501 TGCTGTTTGGACAGAAAACAGTAGTTAGAATCTGTTTCGAGTGTACTGAAAGAACTATTA 13560
|||||||||||||||||||||||||||||||||||||||||||||||||||| |||||||
Old 13501 TGCTGTTTGGACAGAAAACAGTAGTTAGAATCTGTTTCGAGTGTACTGAAAGGACTATTA 13560</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="6"| 2011-02-03
| rowspan="6"| [https://www.yeastgenome.org/locus/YBR203W YBR203W]
| 631936
| 631936
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 631924
| 631924
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 631912
| 631912
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 631907
| 631907
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 631342
| 631353
| Substitution
| GCTGGCGAAACG
| CGTTTCGCCAGC
|- style="height:30px; width:30px; text-align:center;"
| 631940
| 631940
| Substitution
| C
| A
|-
| || colspan="6" | Nucleotide changes within the coding region of COS111/YBR203W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 727-731 are now TFRQH rather than SWRND, residue 917 is now Asparagine rather than Serine, and residue 921 is now Glutamic Acid rather than Glycine.
<pre>New 631303 TGTGTGGTGCAGGCAATATATGGTAAAGTATTTTGTAATGAGGACGTTTCGCCAGCATTT 631362
|||||||||||||||||||||||||||||||||||||||||||| | || | ||||
Old 631298 TGTGTGGTGCAGGCAATATATGGTAAAGTATTTTGTAATGAGGAGCTGGCGAAACGATTT 631357
New 631903 TGTTGGCGAAAATAACTACTATGCTGAAAGCATCATATAACGACTGCTCTCTTTTAACAG 631962
||||||||| |||| ||||||||||| ||||||||||| ||| |||||||||||||||||
Old 631898 TGTTGGCGAGAATAGCTACTATGCTGGAAGCATCATATGACGCCTGCTCTCTTTTAACAG 631957</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR285W YBR285W]
| 774080
| 774080
| Substitution
| C
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of YBR285W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 55 is now Aspartic Acid rather than Histidine.
<pre>New 774041 CTTAGAAAGCCCCACTGACGATAGCATGGAGGCGGACATTTCAGATAGAGAAATGGCTAC 774100
||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||
Old 774037 CTTAGAAAGCCCCACTGACGATAGCATGGAGGCGGACATTTCACATAGAGAAATGGCTAC 774096</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR204C YBR204C]
| 633189
| 633189
| Substitution
| T
| A
|-
| || colspan="6" | A single nucleotide substitution within the coding region of YBR204C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 63 is now Valine rather than Glutamic Acid.
<pre>New 633163 CCTTATTCTTGAATTTCGATCCGATAGTTGTACATTAAAAAACTCCTCATGTTCTGCGAT 633222
||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||||
Old 633158 CCTTATTCTTGAATTTCGATCCGATAGTTGTTCATTAAAAAACTCCTCATGTTCTGCGAT 633217</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBR202W YBR202W]
| 627486
| 627487
| Substitution
| AT
| TA
|- style="height:30px; width:30px; text-align:center;"
| 627433
| 627439
| Substitution
| ATCCGGG
| CTTTGAA
|- style="height:30px; width:30px; text-align:center;"
| 627421
| 627421
| Substitution
| T
| G
|-
| || colspan="6" | Nucleotide changes within the coding region of MCM7/YBR202W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 552-558 is now GINTTLN rather than VINTNPG, and residue 574 is now Tyrosine rather than Isoleucine.
<pre>New 627403 AACAATTTCGATATCCAAGGCGGGTATCAATACAACTTTGAACGCCAGAACCTCAATCTT 627462
||||||||||||||||||||||| ||||||||||| | | ||||||||||||||||||
Old 627398 AACAATTTCGATATCCAAGGCGGTTATCAATACAAATCCGGGCGCCAGAACCTCAATCTT 627457
New 627463 AGCGGCAGCAAATCCGTTGTATGGTAGATATAATCCTAGATTATCACCTCTGGACAATAT 627522
|||||||||||||||||||||||||||| ||||||||||||||||||||||||||||||
Old 627458 AGCGGCAGCAAATCCGTTGTATGGTAGAATTAATCCTAGATTATCACCTCTGGACAATAT 627517</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL080C YBL080C]
| 73450
| 73450
| Substitution
| C
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of PET112/YBL080C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 415 is now Proline rather than Alanine.
<pre>New 73438 CGAAAACCGGAGGAGGCAAAATTTCTTTTGCTTTGGCCAATGGAATTTGTAGCTTGTTCA 73497
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Old 73435 CGAAAACCGGAGGAGCCAAAATTTCTTTTGCTTTGGCCAATGGAATTTGTAGCTTGTTCA 73494</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL067C YBL067C]
| 95345
| 95345
| Substitution
| G
| T
|-
| || colspan="6" | A single nucleotide substitution within the coding region of UBP13/YBL067C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 180 is now Glutamine rather than Histidine.
<pre>New 95333 TCTTTCTTGGTTGATCAGATTCTCTTGATTTTTTTGGAAATTGCAATATATTTTCACGTA 95392
|||||||||| |||||||||||||||||||||||||||||||||||||||||||||||||
Old 95335 TCTTTCTTGGGTGATCAGATTCTCTTGATTTTTTTGGAAATTGCAATATATTTTCACGTA 95394</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR074W YBR074W]
| 388774
| 388775
| Substitution
| TT
| AA
|-
| || colspan="6" | Nucleotide substitutions within the coding region of YBR074W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 832 is now Asparagine rather than Phenylalanine.
<pre>New 388738 ACGAACCAATAGTTGCAGAGTTACTTTTGGAGGTGAAGGAGAACAGGGCTTGCACTTTAA 388797
||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 388733 ACGAACCAATAGTTGCAGAGTTACTTTTGGAGGTGAAGGAGTTCAGGGCTTGCACTTTAA 388792</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR073W YBR073W]
| 385360
| 385361
| Substitution
| CG
| GC
|-
| || colspan="6" | Nucleotide substitutions within the coding region of RDH54/YBR073W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 752 is now Alanine rather than Arginine.
<pre>New 385318 TCTTGTTGAGTGCAAAATCGGGAGGTGTAGGATTGAATCTAGTCGGTGCTTCGCGACTTA 385377
||||||||||||||||||||||||||||||||||||||||||||||| |||||||||||
Old 385313 TCTTGTTGAGTGCAAAATCGGGAGGTGTAGGATTGAATCTAGTCGGTCGTTCGCGACTTA 385367</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR152W YBR152W], [https://www.yeastgenome.org/locus/YBR153W YBR153W]
| 547442
| 547442
| Substitution
| A
| T
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs SPP381/YBR152W and RIB7/YBR153W.
<pre>New 547425 GCTTCTTTGTATTACTATCAACATTTTTAGAAGATATGTCTTTGACACCACTGTGTGAAG 547484
||||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||
Old 547419 GCTTCTTTGTATTACTATCAACAATTTTAGAAGATATGTCTTTGACACCACTGTGTGAAG 547478</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBLCtau1 YBLCtau1], [https://www.yeastgenome.org/locus/tF(GAA)B tF(GAA)B]
| 36312
| 36312
| Substitution
| T
| A
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between Ty4 LTR YBLCtau1 and tRNA-Phe tF(GAA)B.
<pre>New 36299 TGTGCTTCAGTATTACATTTTTTGCCTTCAACGCCTTGATTGTTCTATTTTTGCTAATAA 36358
|||||||||||||||| |||||||||||||||||||||||||||||||||||||||||||
Old 36296 TGTGCTTCAGTATTACTTTTTTTGCCTTCAACGCCTTGATTGTTCTATTTTTGCTAATAA 36355</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL099W YBL099W], [https://www.yeastgenome.org/locus/tF(GAA)B tF(GAA)B]
| 36673
| 36673
| Substitution
| A
| T
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between tRNA-Phe tF(GAA)B and ORF ATP1/YBL099W.
<pre>New 36659 ATTTATTGTAATTATTATACATTGGTCATATCAAATTCACATCAGACTTCAATTTTTCAA 36718
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 36656 ATTTATTGTAATTATTAAACATTGGTCATATCAAATTCACATCAGACTTCAATTTTTCAA 36715</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR006W YBR006W], [https://www.yeastgenome.org/locus/YBR007C YBR007C]
| 248623
| 248623
| Insertion
|
| T
|-
| || colspan="6" | A single nucleotide insertion was made in the intergenic region between ORFs UGA2/YBR006W and DSF2/YBR007C.
<pre>New 248572 GCATGTATAAATACTCTACTCCTCGTATATAGAAAGTTAAGTAAATTTTTTGAAAGAAAA 248631
|||||||||||||||||||||||||||||||||||||||||||||||||| |||||||||
Old 248574 GCATGTATAAATACTCTACTCCTCGTATATAGAAAGTTAAGTAAATTTTT-GAAAGAAAA 248632</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR001C YBR001C], [https://www.yeastgenome.org/locus/YBR002C YBR002C]
| 241396
| 241396
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 241359
| 241359
| Substitution
| G
| A
|-
| || colspan="6" | Two separate single nucleotide substitutions were made in the intergenic region between ORFs NTH2/YBR001C and RER2/YBR002C.
<pre>New 241352 AAAGGAAAAATATAAATAAATAAATAAAATTGAGAAATAAAGATATTTAGTTTTAATGGA 241411
||||| |||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 241354 AAAGGGAAAATATAAATAAATAAATAAAATTGAGAAATAAAGGATATTAGTTTTAATGGA 241413</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL005W YBL005W], [https://www.yeastgenome.org/locus/YBLWdelta8 YBLWdelta8]
| 220413
| 220414
| Substitution
| AG
| GA
|-
| || colspan="6" | A dinucleotide substitution was made in the intergenic region between ORF PDR3/YBL005W and Ty1 LTR YBLWdelta8.
<pre>New 220372 ATGACAATACTTCATATCCCTTCTTATGAAAACGCAAAGAAAATAGGGAAGCAGAGCATA 220431
|||||||||||||||||||||||||||||||||||||| ||||||||||||||||||||
Old 220375 ATGACAATACTTCATATCCCTTCTTATGAAAACGCAAAAGAAATAGGGAAGCAGAGCATA 220434</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBL105C YBL105C], [https://www.yeastgenome.org/locus/YBL106C YBL106C]
| 13982
| 13982
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 13966
| 13966
| Substitution
| C
| A
|-
| || colspan="6" | Two separate single nucleotide substitutions were made in the intergenic region between ORFs SRO77/YBL106C and PKC1/YBL105C.
<pre>New 13941 AGAAATATGTTAGTAGTAATATAATACTGAGCTGTTTCTTAAATGCTTCCTTAATAATGT 14000
||||||||||||||||||||||||| ||||||||||||||| ||||||||||||||||||
Old 13941 AGAAATATGTTAGTAGTAATATAATCCTGAGCTGTTTCTTAGATGCTTCCTTAATAATGT 14000</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="6"| 2011-02-03
| rowspan="6"| [https://www.yeastgenome.org/locus/ARS209 ARS209]
| 254720
| 254720
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 254719
| 254719
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 254616
| 254616
| Substitution
| T
| A
|- style="height:30px; width:30px; text-align:center;"
| 254548
| 254548
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 254532
| 254532
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 254495
| 254495
| Substitution
| G
| T
|-
| || colspan="6" | Several nucleotide changes were made within ARS209.
<pre>New 254452 AAATATCCTTTTTTTTTTCTTTGCATTTGTCTTCTTTCATTTTAAATCTTCATAATCTTC 254511
|||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 254453 AAATATCCTTTTTTTTTTCTTTGCATTTGTCTTCTTTCATTTGAAATCTTCATAATCTTC 254512
New 254512 CGGAAAAACTAGTGATGCGAAATATTGTAGAGAAAAAGCGCAGGGCATTCCTATACTTAG 254571
||||||||||||||||||| |||||||||||||||| |||||||||||||||||||||||
Old 254513 CGGAAAAACTAGTGATGCGCAATATTGTAGAGAAAA-GCGCAGGGCATTCCTATACTTAG 254571
New 254572 TAATCACCATCATAACGTATTTTAAAATGAAGAAGCGAACCTCAAAGAATTTTCTATACA 254631
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 254572 TAATCACCATCATAACGTATTTTAAAATGAAGAAGCGAACCTCATAGAATTTTCTATACA 254631
New 254692 TATATTGCAGAAAATGTGCTAGTAATATTGTTCTCTCTGTTGTCAATGGGCTTACAATTG 254751
|||||||||||||||||||||||||||| | |||||||||||||||||||||||||||||
Old 254692 TATATTGCAGAAAATGTGCTAGTAATAT-G-TCTCTCTGTTGTCAATGGGCTTACAATTG 254749</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR285W YBR285W], [https://www.yeastgenome.org/locus/YBR286W YBR286W]
| 774430
| 774430
| Substitution
| C
| G
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs YBR285W and APE3/YBR286W.
<pre>New 774401 CTTATCGTCAGAAAGAGTGTTCTCTATGTTTTTGTGCTTCCATAAATATATAGTTCAAAA 774460
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||
Old 774397 CTTATCGTCAGAAAGAGTGTTCTCTATGTTTTTCTGCTTCCATAAATATATAGTTCAAAA 774456</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/ARS221 ARS221]
| 631981
| 631981
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 631940
| 631940
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 631936
| 631936
| Substitution
| G
| A
|-
| || colspan="6" | Three single nucleotide substitutions were made within ARS221.
<pre>New 631933 CATCATATAACGACTGCTCTCTTTTAACAGCATACGTTCTGTTAATTTATTTGGCCAAAT 631992
|||||||| ||| |||||||||||||||||||||||||||||||||||||||| ||||||
Old 631928 CATCATATGACGCCTGCTCTCTTTTAACAGCATACGTTCTGTTAATTTATTTGACCAAAT 631987</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/ARS213 ARS213]
| 390033
| 390033
| Insertion
|
| C
|-
| || colspan="6" | A single nucleotide insertion was made within ARS213.
<pre>New 389998 ACTGACACTAAAAAAAGGGTCGTACGTCTTACTGGCAGCGCCGAAAAATGTTTCGAAAAT 390057
||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||||
Old 389993 ACTGACACTAAAAAAAGGGTCGTACGTCTTACTGGCAGCGC-GAAAAATGTTTCGAAAAT 390051</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR201C-A YBR201C-A], [https://www.yeastgenome.org/locus/YBR202W YBR202W]
| 625500
| 625500
| Substitution
| T
| C
|- style="height:30px; width:30px; text-align:center;"
| 625435
| 625435
| Insertion
|
| T
|-
| || colspan="6" | A single nucleotide insertion and a single nucleotide substitution were made in the intergenic region between ORFs YBR201C-A and MCM7/YBR202W.
<pre>New 625423 ATTTTCTCAATAACAGGTCGAGGCCCCTTCTACCCTTGAATGCTACTTATTACTCACTCA 625482
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 625419 ATTTTCTCAATAACAGG-CGAGGCCCCTTCTACCCTTGAATGCTACTTATTACTCACTCA 625477
New 625483 TAATACATTGTATAAGCCTTCGCGTTTTTCACGGCCTCGAAAAAATTTTTCTTAACTAAT 625542
|||||||||||||||||||||| |||||||||||||||||||||||||||||||||||||
Old 625478 TAATACATTGTATAAGCCTTCGTGTTTTTCACGGCCTCGAAAAAATTTTTCTTAACTAAT 625537</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR200W-A YBR200W-A], [https://www.yeastgenome.org/locus/YBR201W YBR201W]
| 623444
| 623444
| Deletion
| C
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORFs YBR200W-A and DER1/YBR201W.
<pre>New 623434 GAAGGTATAACAAAA-CAGATAGACACCTAATAAAGAACAAAATATTCCTATAGTTTTGC 623492
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Old 623429 GAAGGTATAACAAAACCAGATAGACACCTAATAAAGAACAAAATATTCCTATAGTTTTGC 623488</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL001C YBL001C], [https://www.yeastgenome.org/locus/YBL002W YBL002W]
| 237021
| 237021
| Insertion
|
| G
|-
| || colspan="6" | A single nucleotide insertion was made in the intergenic region between ORFs HTB2/YBL002W and ECM15/YBL001C.
<pre>New 236992 AGGGTCTAGTCTATCAGCCTCCGAAGGGAGTTGTATAAATGTATATATATAACTTTATAA 237051
||||||||||||||||||||||||||| ||||||||||||||||||||||||||||||||
Old 236995 AGGGTCTAGTCTATCAGCCTCCGAAGG-AGTTGTATAAATGTATATATATAACTTTATAA 237053</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/ARS208 ARS208], [https://www.yeastgenome.org/locus/CEN2 CEN2]
| 238133
| 238133
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 238116
| 238116
| Substitution
| G
| A
|-
| || colspan="6" | Two separate single nucleotide substitutions were made in the intergenic region between ARS208 and CEN2.
<pre>New 238082 AGTACTTGCTTTCAGCAGAAAATGAAAAAAAGAACGTTCAAACAGACTGAAAATATAGCT 238141
|||||||||||||||||||||||||||||||| |||||||||||||||| ||||||||||
Old 238084 AGTACTTGCTTTCAGCAGAAAATGAAAAAAAGGACGTTCAAACAGACTGGAAATATAGCT 238143</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL079W YBL079W], [https://www.yeastgenome.org/locus/YBL080C YBL080C]
| 75208
| 75208
| Substitution
| A
| G
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs PET112/YBL080C and NUP170/YBL079W.
<pre>New 75178 GGAGAATTACTGGAACCTAGGATCTGACAAGCGGACAAAAAAGCAGAGTGCGTTTATTAC 75237
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||
Old 75175 GGAGAATTACTGGAACCTAGGATCTGACAAGCGAACAAAAAAGCAGAGTGCGTTTATTAC 75234</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL077W YBL077W], [https://www.yeastgenome.org/locus/YBL078C YBL078C]
| 80747
| 80747
| Deletion
| T
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORFs ATG8/YBL078C and YBL077W.
<pre>New 80708 TTCAGACTTAAATGTAGACTTCATGTCTCTAGTAATTATTTT-ATTATGATTTTCTCAAC 80766
|||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 80705 TTCAGACTTAAATGTAGACTTCATGTCTCTAGTAATTATTTTTATTATGATTTTCTCAAC 80764</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL072C YBL072C]
| 89277
| 89277
| Substitution
| G
| T
|-
| || colspan="6" | A single nucleotide substitution was made within the 5' UTR intron of ORF RPS8A/YBL072C.
<pre>New 89267 GGCTTGATTTTTTGGGTACACAAAGGATTCAGTTTAGTGCACTGCTCCTGTCACAATTTA 89326
|||||||||||| |||||||||||||||||||||||||||||||||||||||||||||||
Old 89265 GGCTTGATTTTTGGGGTACACAAAGGATTCAGTTTAGTGCACTGCTCCTGTCACAATTTA 89324</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL067C YBL067C], [https://www.yeastgenome.org/locus/YBL068W YBL068W]
| 93622
| 93622
| Deletion
| C
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORFs PRS4/YBL068W and UBP13/YBL067C.
<pre>New 93594 AAAGGAGACGGTGAACCTTTACCTTCC-TTGATATGCAAATATTTTTCAGCTTTTCCTAA 93652
||||||||||||||||||||||||||| ||||||||||||||||||||||||||||||||
Old 93595 AAAGGAGACGGTGAACCTTTACCTTCCCTTGATATGCAAATATTTTTCAGCTTTTCCTAA 93654</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="4"| 2011-02-03
| rowspan="4"| [https://www.yeastgenome.org/locus/YBR077C YBR077C], [https://www.yeastgenome.org/locus/YBR078W YBR078W]
| 392822
| 392822
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 392568
| 392569
| Substitution
| CG
| GC
|- style="height:30px; width:30px; text-align:center;"
| 392557
| 392558
| Substitution
| CG
| GC
|- style="height:30px; width:30px; text-align:center;"
| 392340
| 392340
| Deletion
| TT
|
|-
| || colspan="6" | Several nucleotide changes were made in the intergenic region between ORFs SLM4/YBR077C and ECM33/YBR078W.
<pre>New 392327 GATAACTGCCTTTTTTTTTT--CTTCTTATCTTCCCTTAATTAATTCATTAGAGTCTTTT 392384
|||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||
Old 392321 GATAACTGCCTTTTTTTTTTTTCTTCTTATCTTCCCTTAATTAATTCATTAGAGTCTTTT 392380
New 392545 CACGACCCGGGTGGCTGCTGCGCCCTCGCGAAAAAGAAATGAAATGGAGTGCAAAAACGG 392604
|||||||||||||||| ||||||||| |||||||||||||||||||||||||||||||
Old 392541 CACGACCCGGGTGGCTCGTGCGCCCTCCGGAAAAAGAAATGAAATGGAGTGCAAAAACGG 392600
New 392805 AATGTCAAACACCTACGACTTTTCGCAATCAACGGACCTCTCTTGCATTTTTGTATTTAA 392864
|||||||||||||||||||||| |||||||||||||||||||||||||||||||||||||
Old 392801 AATGTCAAACACCTACGACTTT-CGCAATCAACGGACCTCTCTTGCATTTTTGTATTTAA 392859</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR072C-A YBR072C-A], [https://www.yeastgenome.org/locus/YBR072W YBR072W]
| 382742
| 382742
| Insertion
|
| G
|- style="height:30px; width:30px; text-align:center;"
| 382729
| 382729
| Insertion
|
| G
|-
| || colspan="6" | Two separate single nucleotide insertions were made in the intergenic region between ORFs HSP26/YBR072W and YBR072C-A.
<pre>New 382719 TTGCTTGCATATGGGCTTGAAACATATGGTCATCACATCTGAGCGATTTTACCTCTTAGA 382778
|||||||||||||| ||||||||||||| |||||||||||||||||||||||||||||||
Old 382716 TTGCTTGCATATGG-CTTGAAACATATG-TCATCACATCTGAGCGATTTTACCTCTTAGA 382773</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR066C YBR066C], [https://www.yeastgenome.org/locus/YBR067C YBR067C]
| 371424
| 371424
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 370774
| 370773
| Substitution
| C
| T
|-
| || colspan="6" | A single nucleotide substitution and a single nucleotide insertion were made in the intergenic region between ORFs NRG2/YBR066C and TIP1/YBR067C.
<pre>New 370729 TTGTTCTTCGAACAGTAGCGAGTGCTCATATGACTTGGTGCCGGAAATTCATTTGAGCTG 370788
||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
Old 370727 TTGTTCTTCGAACAGTAGCGAGTGCTCATATGACTTGGTGCCGGAAACTCATTTGAGCTG 370786
New 371389 AAGGTTATAGTCTCCTTTTTTTCTTGGCTTCGGGAAAAATACGATTTGTTTGTTATTCTA 371448
|||||||||||||||||||||||||||||||||||||| |||||||||||||||||||||
Old 371387 AAGGTTATAGTCTCCTTTTTTTCTTGGCTTCGGGAAAA-TACGATTTGTTTGTTATTCTA 371445</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/ARS230 ARS230], [https://www.yeastgenome.org/locus/YBL100W-C YBL100W-C]
| 28909
| 28909
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 28887
| 28887
| Insertion
|
| AT
|-
| || colspan="6" | A dinucleotide insertion and a mononucleotide insertion were made in the intergenic region between ORF YBL100W-C and ARS230.
<pre>New 28859 ATTACTGTTTCGGGAATATAACGTTTGATATCGCTAGCGCACCCAGATGAGAAATCCGCA 28918
||||||||||||||||||||||||||||| |||||||||||||||||||||| ||||||
Old 28859 ATTACTGTTTCGGGAATATAACGTTTGAT--CGCTAGCGCACCCAGATGAGAA-TCCGCA 28915</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/ARS228 ARS228]
| 792273
| 792273
| Insertion
|
| T
|-
| || colspan="6" | A single nucleotide insertion was made within ARS228.
<pre>New 792231 TTTGTTATGAATCTGAAAAGAAAAATACTATTTTAGCAATACAATGAATTTTAAAAAGTT 792290
|||||||||||||||||||||||||||||||||||||||||||||||| |||||||||||
Old 792226 TTTGTTATGAATCTGAAAAGAAAAATACTATTTTAGCAATACAATGAA-TTTAAAAAGTT 792284</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/ARS225 ARS225], [https://www.yeastgenome.org/locus/YBR275C YBR275C]
| 757291
| 757291
| Deletion
| A
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORF RIF1/YBR275C and ARS225.
<pre>New 757242 ATCTTCTTGCTAACGATGAGTCGCCAATAAATAAAAAATCGACG-CGTCGGTCAATTATA 757310
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 757237 ATCTTCTTGCTAACGATGAGTCGCCAATAAATAAAAAATCGACGACGTCGGTCAATTATA 757306</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/ARS208 ARS208]
| 237892
| 237892
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 237839
| 237839
| Substitution
| G
| A
|-
| || colspan="6" | Two separate single nucleotide substitutions were made within ARS208.
<pre>New 237832 TTGCGAAAATTATTCTTTAATAGTTTAACTAAAAGTAAAAAGTTAGAAATCATAAATAAA 237891
||||| |||||||||||||||||||||||||||||||||||||||||||||||||||| |
Old 237834 TTGCGGAAATTATTCTTTAATAGTTTAACTAAAAGTAAAAAGTTAGAAATCATAAATAGA 237893</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL103C YBL103C], [https://www.yeastgenome.org/locus/YBL104C YBL104C]
| 21376
| 21376
| Insertion
|
| A
|-
| || colspan="6" | A single nucleotide insertion was made in the intergenic region between ORFs YBL104C and RTG3/YBL103C.
<pre>New 21361 CTTATGCTATCTTGAAATATATCATCGCCGTAAAGTATGATGTGTAGCGCATTAGTCTTC 21420
|||||||||||||||| |||||||||||||||||||||||||||||||||||||||||||
Old 21361 CTTATGCTATCTTGAA-TATATCATCGCCGTAAAGTATGATGTGTAGCGCATTAGTCTTC 21419</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBL102W YBL102W], [https://www.yeastgenome.org/locus/YBL103C YBL103C]
| 28913
| 28913
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 23855
| 23856
| Deletion
| CC
|
|- style="height:30px; width:30px; text-align:center;"
| 23947
| 23947
| Insertion
|
| A
|-
| || colspan="6" | Several sequence changes were made in the intergenic region between ORFs RTG3/YBL103C and SFT2/YBL102W.
<pre>New 23821 GAAGGCTTTTCTAATCACCATGGCTTTATTATTTC--AAAAGTAACTTGCGAAGAGTCAC 23878
||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
Old 23820 GAAGGCTTTTCTAATCACCATGGCTTTATTATTTCCCAAAAGTAACTTGCGAAGAGTCAC 23879
New 23879 ATCCCGCGGAACGGCCCGCAATCGTGACCCGGCAAAAGGCGATTGTAATGAAGAGGGAGT 23938
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||
Old 23880 ATCCCGCGGAACGGCCCGCAATCGTGACCCGGCCAAAGGCGATTGTAATGAAGAGGGAGT 23939
New 23939 ATTGGTCAAGACTTGTACTATACTGAAATAGGAAGAAGATTGAATAAATTTGCATTCTAA 23998
|||||||| |||||||||||||||||||||||||||||||||||||||||||||||||||
Old 23940 ATTGGTCA-GACTTGTACTATACTGAAATAGGAAGAAGATTGAATAAATTTGCATTCTAA 23998</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR125C YBR125C], [https://www.yeastgenome.org/locus/YBR126C YBR126C]
| 488600
| 488601
| Substitution
| TC
| AT
|-
| || colspan="6" | A dinucleotide substitution was made in the intergenic region between ORFs PTC4/YBR125C and TPS1/YBR126C.
<pre>New 488565 CGTTATGCGGTGTGAACAGCGACAATAAAAAAAAATGTGGGATAAATTATGGCTTTTTTT 488624
||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 488559 CGTTATGCGGTGTGAACAGCGACAATAAAAAAAAATGTGGGTCAAATTATGGCTTTTTTT 488618</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR102C YBR102C], [https://www.yeastgenome.org/locus/YBR103W YBR103W]
| 447535
| 447536
| Substitution
| CG
| GC
|-
| || colspan="6" | A dinucleotide substitution was made in the intergenic region between ORFs EXO84/YBR102C and SIF2/YBR103W.
<pre>New 447525 AAAGGTTATGAGATATGCAAGACCATTCGTTTTGATTTGCAATTAGTGAGAACAATTTAA 447584
|||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 447519 AAAGGTTATGAGATATCGAAGACCATTCGTTTTGATTTGCAATTAGTGAGAACAATTTAA 447578</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBR013C YBR013C], [https://www.yeastgenome.org/locus/YBRCdelta14 YBRCdelta14]
| 265922
| 265922
| Deletion
| C
|
|- style="height:30px; width:30px; text-align:center;"
| 265905
| 265905
| Substitution
| T
| G
|- style="height:30px; width:30px; text-align:center;"
| 265902
| 265902
| Deletion
| C
|
|-
| || colspan="6" | Several nucleotide changes were made within the intergenic region between ORF YBR013C and Ty1 LTR YBRCdelta14.
<pre>New 265852 GATACATATCCTGAATAAGGGATATATCATTATGAGGTTAAGTGGCCTAAAA-ACGCAAT 265910
|||||||||||||||||||||||||||||||||||||||||||||||||||| || ||||
Old 265850 GATACATATCCTGAATAAGGGATATATCATTATGAGGTTAAGTGGCCTAAAACACTCAAT 265909
New 265911 TAATACGGATCC-TTGTACTATTAAGTCTTTTCTATCTCTGAAAATTAACTTAAGAAGCG 265969
|||||||||||| |||||||||||||||||||||||||||||||||||||||||||||||
Old 265910 TAATACGGATCCCTTGTACTATTAAGTCTTTTCTATCTCTGAAAATTAACTTAAGAAGCG 265969</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR295W YBR295W], [https://www.yeastgenome.org/locus/YBR296C YBR296C]
| 796707
| 796707
| Substitution
| A
| G
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs PCA1/YBR295W and PHO89/YBR296C.
<pre>New 796671 TAAATTAGAAAAAAATTAATGCATCTTTAAGGTTTTAAATTAGAAATGTTTTAACTTTAA 796730
|||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 796665 TAAATTAGAAAAAAATTAATGCATCTTTAAGGTTTTAAATTAAAAATGTTTTAACTTTAA 796724</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR292C YBR292C], [https://www.yeastgenome.org/locus/YBR293W YBR293W]
| 786761
| 786761
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 786736
| 786737
| Substitution
| CT
| TC
|-
| || colspan="6" | Several nucleotide changes were made in the intergenic region between ORFs YBR292C and YBR293W.
<pre>New 786721 TTCCAAATCAGATTTTTTTTCGCAATGCTTAAATCTAGTAAACACAAAGTACTACCGAAA 786780
||||||||||||||||||| |||||||||||||||||||||||| ||||||||||||||
Old 786717 TTCCAAATCAGATTTTTTTCTGCAATGCTTAAATCTAGTAAACAC-AAGTACTACCGAAA 786776
New 786761 AACACAAAGTACTACCGAAAAGCAAGGATGGAAACTATGGCAGTATTGAAGAGACTGAAA 786820
||||| ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Old 786757 AACAC-AAGTACTACCGAAAAGCAAGGATGGAAACTATGGCAGTATTGAAGAGACTGAAA 786815</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="4"| 2011-02-03
| rowspan="4"| [https://www.yeastgenome.org/locus/YBL098W YBL098W], [https://www.yeastgenome.org/locus/YBL099W YBL099W]
| 38920
| 38920
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 38917
| 38917
| Substitution
| C
| T
|- style="height:30px; width:30px; text-align:center;"
| 38800
| 38800
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 38728
| 38728
| Substitution
| C
| A
|-
| || colspan="6" | Several single nucleotide substitutions were made in the intergenic region between ORFs ATP1/YBL099W and BNA4/YBL098W.
<pre>New 38699 AAAAAAATAAAAATGAATATAAGGTACGTCTCAAAAAGAAATGTAAATATAGAAATTTTA 38758
|||||||||||||||||||||||||||||||| |||||||||||||||||||||||||||
Old 38696 AAAAAAATAAAAATGAATATAAGGTACGTCTCCAAAAGAAATGTAAATATAGAAATTTTA 38755
New 38759 AAAAAAAAAACGAAAAAAAACATAACTAAATTTAAAGTGCAGCCAAACAATAACCCTGAA 38818
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 38756 AAAAAAAAAACGAAAAAAAACATAACTAAATTTAAAGTGCAGCCCAACAATAACCCTGAA 38815
New 38879 GTAAATAATGCCCCTACTTTTCTTCTAAGGAAATGAGTTACTACAAAAATAAGGAAATAT 38938
|||||||||||||||||||||||||||||||| |||||||| || |||||||||||||||
Old 38876 GTAAATAATGCCCCTACTTTTCTTCTAAGGAAGTGAGTTACCACCAAAATAAGGAAATAT 38935</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL092W YBL092W], [https://www.yeastgenome.org/locus/YBL093C YBL093C]
| 45495
| 45495
| Substitution
| T
| A
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs ROX3/YBL093C and RPL32/YBL092W.
<pre>New 45479 ACTGGAGAAGAGTGTTTGAATCCAGCAGAAGGTAATACGCACCTTTCTCATCTATTTGCA 45538
||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||
Old 45476 ACTGGAGAAGAGTGTTTGATTCCAGCAGAAGGTAATACGCACCTTTCTCATCTATTTGCA 45535</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL087C YBL087C], [https://www.yeastgenome.org/locus/YBL088C YBL088C]
| 59406
| 59406
| Insertion
|
| T
|-
| || colspan="6" | A single nucleotide insertion was made in the intergenic region between ORFs TEL1/YBL088C and RPL23A/YBL087C.
<pre>New 59399 ATTTCCCTTTTTCTTTGAAGGCTTTTTTTTCGAATTTCCTGCTTTTTTTGCGAGGCTTTG 59458
||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||
Old 59396 ATTTCCCTTTT-CTTTGAAGGCTTTTTTTTCGAATTTCCTGCTTTTTTTGCGAGGCTTTG 59454</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL086C YBL086C], [https://www.yeastgenome.org/locus/YBL087C YBL087C]
| 61056
| 61056
| Deletion
| T
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORFs RPL23A/YBL087C and YBL086C.
<pre>New 61019 AAAAACTTGGTCTGTTGAAAATAATAACTGCATGGGTTTTT-CAAAGCAGTTGGGGGTGT 61077
||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||||
Old 61015 AAAAACTTGGTCTGTTGAAAATAATAACTGCATGGGTTTTTTCAAAGCAGTTGGGGGTGT 61074</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR205W YBR205W], [https://www.yeastgenome.org/locus/YBR207W YBR207W]
| 634934
| 634934
| Substitution
| C
| T
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs KTR3/YBR205W and FTH1/YBR207W.
<pre>New 634903 ATATACACATAATTCAATGTAGTAGCCACCTCACTTTATTCTAGTGCCTTCTTGGGTTCA 634962
|||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
Old 634898 ATATACACATAATTCAATGTAGTAGCCACCTCACTTCATTCTAGTGCCTTCTTGGGTTCA 634957</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR038W YBR038W], [https://www.yeastgenome.org/locus/YBR039W YBR039W]
| 315270
| 315271
| Substitution
| CG
| GC
|- style="height:30px; width:30px; text-align:center;"
| 315071
| 315071
| Deletion
| G
|
|-
| || colspan="6" | A single nucleotide deletion and a dinucleotide substitution were made in the intergenic region between ORFs CHS2/YBR038W and ATP3/YBR039W.
<pre>New 315050 TGTATGAGCTGGGCATCAAGAG-CTTTTGAGATTTTCCAAGTAGTAACTCATCTTTCTGA 315108
|||||||||||||||||||||| |||||||||||||||||||||||||||||||||||||
Old 315049 TGTATGAGCTGGGCATCAAGAGGCTTTTGAGATTTTCCAAGTAGTAACTCATCTTTCTGA 315108
New 315229 TCGATAAAACAAAAAAAAAGTAAGAAGATATATGAATAGGAGCTGTCGCTAGAACTAGTA 315288
||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 315229 TCGATAAAACAAAAAAAAAGTAAGAAGATATATGAATAGGACGTGTCGCTAGAACTAGTA 315288</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR036C YBR036C], [https://www.yeastgenome.org/locus/YBR037C YBR037C]
| 310457
| 310457
| Insertion
|
| T
|-
| || colspan="6" | A single nucleotide insertion was made in the intergenic region between ORFs CSG2/YBR036C and SCO1/YBR037C.
<pre>New 310430 TCCTTTAGAGTGAGAGAGCTTTTTTTTTTCTTGCGATACACCTTCGCCGGGTGATAGCCG 310489
|||||||||||||||||||||||||||| |||||||||||||||||||||||||||||||
Old 310430 TCCTTTAGAGTGAGAGAGCTTTTTTTTT-CTTGCGATACACCTTCGCCGGGTGATAGCCG 310488</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR160W YBR160W], [https://www.yeastgenome.org/locus/YBR161W YBR161W]
| 561435
| 561435
| Deletion
| C
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORFs CDC28/YBR160W and CSH1/YBR161W.
<pre>New 561405 GCAAATTCATTGCTCTTTGAATTTTGAAGAGTTTCA-TTGTCACCGTTGAATAACCGAGA 561463
|||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
Old 561399 GCAAATTCATTGCTCTTTGAATTTTGAAGAGTTTCACTTGTCACCGTTGAATAACCGAGA 561458</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2004-07-16
| [https://www.yeastgenome.org/locus/YBL066C YBL066C]
| 96812
| 96962
| Substitution
| GTGGTTGGATAGAGAACAGTGTTAG TCCCGTAGAATCGTGGTCGTTGTTC TATGATATCAACTTTGGAACAACTC AGAGGTGGATATCCCGTCTTTTAGA GGACCGGGGTCGGACGCGGAATCCA ACTGTCATATATTGACCGAAACAAA G
| GATGGTTTGGAAGTTAGAAGAAGTT ACAGTGTTAGTGCCCGTAGAAAATC GTTGGTTCGTTTTGTTGCTATTGAT ATCATTACTTTTGGAAAACAAGCTC AGAGGTGGATATGCCGTGCTTTTAG AGGAGCCGGGGTCGGAAACGACGGA ATGCAAATCTGTCATATTATTTGAC TTCGAAGCAATCG
|-
| || colspan="6" | SGD re-sequenced this region in S288C and found that 37 nucleotide insertions and 4 nucleotide changes were necessary to correct the reference sequence. As a consequence of these changes, SEF1/YBL066C was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 1,057 to 1,148 amino acids.
<pre>New: 1 TGTTTCCAGGAGTCTTCACGTTGTTTTCATTATCGATGGTTTGGAAGTTAGAAGAAGTTA 60
||||||||||||||||||||||||||||||||||| ||||| ||| ||| ||||
Current: 96777 TGTTTCCAGGAGTCTTCACGTTGTTTTCATTATCG-TGGTT-GGA---TAG-AGAA---- 96826

New: 61 CAGTGTTAGTGCCCGTAGAAAATCGTTGGTTCGTTTTGTTGCTATTGATATCATTACTTT 120
|||||||||| ||||||||| |||| || ||||| ||| ||| |||||||| |||||
Current: 96827 CAGTGTTAGT-CCCGTAGAA--TCGT-GG-TCGTT--GTT-CTA-TGATATCA--ACTTT 96875

New: 121 TGGAAAACAAGCTCAGAGGTGGATATGCCGTGCTTTTAGAGGAGCCGGGGTCGGAAACGA 180
|||| ||| ||||||||||||||| |||| ||||||||||| ||||||||||| ||
Current: 96876 -GGAA--CAA-CTCAGAGGTGGATATCCCGT-CTTTTAGAGGA-CCGGGGTCGGA--CG- 96926

New: 181 CGGAATGCAAATCTGTCATATTATTTGACTTCGAAGCAATCGGTGTACGTGAATGGGACA 240
|||||| ||| ||||||||| | ||||| |||| ||| |||||||||||||||||||
Current: 96927 CGGAATCCAA--CTGTCATAT-A-TTGAC--CGAAACAAA-GGTGTACGTGAATGGGACA 96979 </pre>
|- style="height:30px; width:30px; text-align:center;"
| 2004-07-13
| [https://www.yeastgenome.org/locus/YBL067C YBL067C]
| 93899
| 93899
| Insertion
|
| A
|-
| || colspan="6" | The work of Kellis et al. 2003 predicted the insertion of a single nucleotide; this sequence error was confirmed in S288C by SGD. As a consequence of this sequence change, UBP13/YBL067C was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 688 to 747 amino acids.
<pre>New: 93883 TCGCTTTATAAAACAAAACATATGCTGTTGCCATATTTGGAGATTCACCTGTGAATTCTA 93942
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old: 93883 TCGCTTTATAAAACAAA-CATATGCTGTTGCCATATTTGGAGATTCACCTGTGAATTCTA 93941 </pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| 2004-07-12
| [https://www.yeastgenome.org/locus/YBR062C YBR062C]
| 366383
| 366383
| Deletion
| T
|
|-
| || colspan="6" | The work of Cliften et al. 2003 predicted that there is a sequencing error in YBR062C: an single nucleotide should be deleted 100 nt upstream of the currently annotated start site. Assuming this sequence change, Cliften et al. further propose a new intron and 5' exon, and a framechange for this ORF. When spliced, this ORF would now encode a predicted protein of 180 amino acids. This sequence error was confirmed in S288C by SGD and the coordinates have been changed accordingly (start was moved upstream 195 nt and an intron was added at relative coordinates 17-98).
<pre> New: AAAGTTTTGAAATAGACCTTGCAGTTGGGATCT-GACCTGTCTTCTCTGCTCCTCCTGTG
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||
Old: AAAGTTTTGAAATAGACCTTGCAGTTGGGATCTTGACCTGTCTTCTCTGCTCCTCCTGTG </pre>
Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|- style="height:30px; width:30px; text-align:center;"
| 2004-07-09
| [https://www.yeastgenome.org/locus/YBR108W YBR108W]
| 457298
| 457298
| Insertion
|
| G
|-
| || colspan="6" | The work of Kellis et al. 2003 predicted the insertion of a single G after the G at chromosomal coordinate 457298. This sequence error was confirmed in strain S288C by SGD. As a consequence of this sequence change which caused a frameshift, YBR108W was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 848 to 947 amino acids.
<pre>New: CGGTTCGAAAAAAGTGAAGGACTCTAGCCCTGTTCCCTCAGATCTAGATGAAAAATATGT
||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||
Old: CGGTTCGAAAAAAGTGAAG-ACTCTAGCCCTGTTCCCTCAGATCTAGATGAAAAATATGT</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| 2004-01-29
| [https://www.yeastgenome.org/locus/YBL097W YBL097W]
| 40900
| 40901
| Deletion
| GA
|
|-
| || colspan="6" | Kellis et al. 2003 predicted and confirmed the deletion of two nucleotides (GA) at chromosomal coordinates 40900-40901. As a consequence of this deletion, YBL097W was extended at the 5' end, altering the N-terminus and increasing the predicted protein from 728 to 754 amino acids.
<pre>New 61 TTTACCAATAGA--TCCACCATGATGGCAAATTTTGAAGAATGGATCAAAATGGCTACAG 118
|||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||
Old 40888 TTTACCAATAGAGATCCACCATGATGGCAAATTTTGAAGAATGGATCAAAATGGCTACAG 40947</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| 2004-01-29
| [https://www.yeastgenome.org/locus/YBL013W YBL013W]
| 203180
| 203180
| Insertion
|
| C
|-
| || colspan="6" | A single C nucleotide insertion was confirmed by sequencing genomic DNA from FY23 (S288C) and a D273-10B related strain; GenBank accession number for FY23 is AY490279. The stop codon of ORF YBL013W has been moved downstream, so that the ORF is now 1206 nucleotides long as opposed to the previously annotated 1182 nt.
<pre>New 1141 GGCCAGTTCATGGCGCGCCTGCGGAAAAGATGCGGCGCCCTGAGTGAAAAGTTAGTTTTC 1200
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 203163 GGCCAGTTCATGGCGCG-CTGCGGAAAAGATGCGGCGCCCTGAGTGAAAAGTTAGTTTTC 203221</pre>
|- style="height:30px; width:30px; text-align:center;"
| 2004-01-28
| [https://www.yeastgenome.org/locus/YBL006C YBL006C], [https://www.yeastgenome.org/locus/YBL006W-A YBL006W-A]
| 216785
| 216785
| Deletion
| G
|
|-
| || colspan="6" | Kellis et al. 2003 predicted and confirmed the deletion of a single nucleotide at 216785. As a consequence of this sequence change, YBL006C was extended at the 3' end, altering the C-terminus and increasing the predicted protein from 145 to 180 amino acids. In addition, YBL006W-A was extended at the 3' end, altering the C-terminus and increasing size of the predicted protein from 39 to 49 amino acids.
<pre>New 301 TCAAGTGTCGA-CTTTTCGCACCATTTCCACCGCACATTAGAATGCAAAGCTGCTCTAGA 359
||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||
Old TCAAGTGTCGACCTTTTCGCACCATTTCCACCGCACATTAGAATGCAAAGCTGCTCTAGA</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="5"| 2004-01-26
| rowspan="5"| [https://www.yeastgenome.org/locus/YBL103C-A YBL103C-A], [https://www.yeastgenome.org/locus/YBL104C YBL104C]
| 21279
| 21279
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 18364
| 18364
| Insertion
|
| G
|- style="height:30px; width:30px; text-align:center;"
| 21288
| 21288
| Insertion
|
| C
|- style="height:30px; width:30px; text-align:center;"
| 21345
| 21345
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 21347
| 21347
| Insertion
|
| A
|-
| || colspan="6" | Brachat et al. 2003 and Kellis et al. 2003 predicted and confirmed DIFFERENT sequence changes for YBL104C. Brachat et al. demonstrated the insertion of a single G nt, which extended the 3' end by 141 nt and altered the C-terminus, resulting in overlapping ORF YBL103C-A becoming part of YBL104C (Cliften et al. also predicted this change).
<pre> New: CTTCTGTCTGCATTGGATCGCGTGATTGCGTCCCATTTATTACAAAAGGTAAGTTTGACG
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Previous: 18350 CTTCTGTCTGCATTG-ATCGCGTGATTGCGTCCCATTTATTACAAAAGGTAAGTTTGACG 18408</pre>
Kellis et al. demonstrated the insertion of four separate nucleotides (a single T, a single C, and two separate As), which extended at the 5' end by 198 nt and altered the N-terminus. The inserted C (G on the opposite, coding strand) is the third nucleotide of the new ATG start codon.
<pre> New: ATTATCATATGACCAATGGGTCACTTTTTTGATGAGACCCATGTTTATTCTTCTATACGT
||||||||||||||||||||||||||||| ||||||||| ||||||||||||||||||||
Previous: 21251 ATTATCATATGACCAATGGGTCACTTTTT-GATGAGACC-ATGTTTATTCTTCTATACGT 21308
New: TCGTGATACTGCACTTACGACTACCAGTAACATCAGAATAACCATAGAGC
||||||||||||||||||||||||||||||||||||| || |||||||||
Previous: 21309 TCGTGATACTGCACTTACGACTACCAGTAACATCAGA-TA-CCATAGAGC 21356</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Brachat S, et al.''' (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45. 
[https://www.yeastgenome.org/reference/S000073670 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12844361 PubMed] | [https://genomebiology.biomedcentral.com/articles/10.1186/gb-2003-4-7-r45 Full-Text] 
Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|- style="height:30px; width:30px; text-align:center;"
| 2004-01-21
| [https://www.yeastgenome.org/locus/YBR041W YBR041W]
| 320081
| 320082
| Deletion
| CC
|
|-
| || colspan="6" | Kellis et al. 2003 and Brachat et al. 2003 independently predicted and confirmed the deletion of two C nucleotides from YBR041W. As a consequence of this change, YBR041W was extended at the 3' end, altering the C-terminus and increasing the predicted protein from 623 to 669 amino acids.
<pre> New: TCTTATGCTATGCCCCTATTTGTTAAATTTGTTGATGAAATTAAAATGACAGATAA--TC
|||||||||||||||||||||||||||||||||||||||||||||||||||||||| ||
Previous: 320025 TCTTATGCTATGCCCCTATTTGTTAAATTTGTTGATGAAATTAAAATGACAGATAACCTC 320084</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Brachat S, et al.''' (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45. 
[https://www.yeastgenome.org/reference/S000073670 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12844361 PubMed] | [https://genomebiology.biomedcentral.com/articles/10.1186/gb-2003-4-7-r45 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2004-01-20
| [https://www.yeastgenome.org/locus/YBR157C YBR157C]
| 553996
| 553996
| Insertion
|
| G
|-
| || colspan="6" | Kellis et al. 2003 predicted and confirmed the insertion of a single G nt after the C at chromosomal coordinate 553996. As a consequence of this sequence change, YBR157C was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 106 to 255 amino acids.
<pre> New: TATGGAGGAATTTCTCCTCGTTTTCACACCATCCTTGTCTCCAGGGAAAGAGTAGGTCTT
||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||
Previous: 553978 TATGGAGGAATTTCTCCTC-TTTTCACACCATCCTTGTCTCCAGGGAAAGAGTAGGTCTT 554036</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2004-01-09
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR269C YBR269C]
| 742165
| 742165
| Insertion
|
| G
|- style="height:30px; width:30px; text-align:center;"
| 742175
| 742175
| Insertion
|
| G
|-
| || colspan="6" | Kellis et al. 2003 predicted and confirmed the insertion of G after the G at chromosomal coordinate 742165, and the insertion of another G after the G at 742175. As a consequence of these sequence changes, YBR269C was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 130 to 138 amino acids. This sequence change was incorporated at MIPS prior to SGD, and was verified in strain S288C.
<pre> New: ACGAATAATCGCCGTGTCTCAACGGGTCCTGCTTGGGACCCCCAACTTCACCAGTCTTGG
||||||||||||||||||||||||| |||||||||| |||||||||||||||||||||||
Previous: 742141 ACGAATAATCGCCGTGTCTCAACGG-TCCTGCTTGG-ACCCCCAACTTCACCAGTCTTGG</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2003-09-29
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR074W YBR074W], [https://www.yeastgenome.org/locus/YBR075W YBR075W]
| 387625
| 387625
| Deletion
| G
|
|- style="height:30px; width:30px; text-align:center;"
| 387430
| 387430
| Deletion
| C
|
|-
| || colspan="6" | Due to deletion of a C after the C at position 387430 and a deletion of G after the G at position 387625, YBR074W and YBR075W were merged. After merging YBR074W (386243 - 387484 (1-1242)) and YBR075W (387793 - 389175 (1-1383)), the coordinates of the merged ORF, YBR074W, are 386243 - 389173 (1 - 2931). YBR075W is now an alias of YBR074W. These sequence changes were verified in S288c strain by SGD.
<pre>Query: 1141 TCTCGTGATAGAATGACTTGGAAATCTTATTCATGGCTATCGTGGAC-ACGCTTTCCTCT 1199
||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
Sbjct: 387383 TCTCGTGATAGAATGACTTGGAAATCTTATTCATGGCTATCGTGGACCACGCTTTCCTCT 387442
Query: 1380 AAG-CCTATCAATTATCGAATTGTTCATTATTTTATGGACCATTTTACTTTTTACGTCGA 1438
||| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 387623 AAGGCCTATCAATTATCGAATTGTTCATTATTTTATGGACCATTTTACTTTTTACGTCGA 387682</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Brachat S, et al.''' (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45. 
[https://www.yeastgenome.org/reference/S000073670 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12844361 PubMed] | [https://genomebiology.biomedcentral.com/articles/10.1186/gb-2003-4-7-r45 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2003-01-03
| [https://www.yeastgenome.org/locus/YBR098W YBR098W], [https://www.yeastgenome.org/locus/YBR100W YBR100W]
| 442868
| 442868
| Deletion
| C
|
|-
| || colspan="6" | Due to a change to the systematic sequence of chromosome II (C deletion at 442868), YBR098W and YBR100W have been merged to one single ORF of 691 aa. MMS4 is the standard name for the new, elongated ORF after merging; YBR100W and SLX2 are its aliases. The new coordinates of MMS4/YBR098W are 441473-443548, for a coding sequence of 2076 nt.
We thank Jim Brown (james.brown@stanford.edu), and Kirk Ehmsen (ktehmsen@ucdavis.edu) for reporting this sequence error on Chr II, which was verified in the FY1679 (S288c derivative) strain background by SGD.
<pre>Old: 442861 AGAAAACCGTTTTGATTCTATATTATGATGCGCAAGAATTTTTTGAACAATACACTTCAC 442920
||||||| ||||||||||||||||||||||||||||||||||||||||||||||||||||
New: 442861 AGAAAAC-GTTTTGATTCTATATTATGATGCGCAAGAATTTTTTGAACAATACACTTCAC 442919</pre>
'''Xiao W, et al.''' (1998) Mms4, a putative transcriptional (co)activator, protects Saccharomyces cerevisiae cells from endogenous and environmental DNA damage. Mol Gen Genet 257(6):614-23 
[https://www.yeastgenome.org/reference/S000044724 SGD paper] | [PubMed https://www.ncbi.nlm.nih.gov/pubmed/9604884] | [https://link.springer.com/article/10.1007%2Fs004380050689 Full-Text] 
'''Kaliraman V, et al.''' (2001) Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease. Genes Dev 15(20):2730-40 
[https://www.yeastgenome.org/reference/S000068964 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/11641278 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC312806/ Full-Text] 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Brachat S, et al.''' (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45. 
[https://www.yeastgenome.org/reference/S000073670 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12844361 PubMed] | [https://genomebiology.biomedcentral.com/articles/10.1186/gb-2003-4-7-r45 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2003-01-02
| [https://www.yeastgenome.org/locus/YBR086C YBR086C]
| 422272
| 422273
| Substitution
| TA
| AT
|-
| || colspan="6" | We received a direct notification from MIPS about the following sequence changes; we did not have this change in SGD, so the sequence was edited: The T at 422272 was changed to an A, and the A at 422273 was changed to a T. These differences changed amino acid residue 243 of IST2/YBR086C from Tyr (TAC) -> Ile (ATC). The coordinates of YBR086C are not changed due to this sequence update. References: (1) Sequence verification in FY1679 (S288c derivative strain) background by SGD, (2) Personal communication from Anna Kurlandzka (ania218@poczta.ibb.waw.pl).
<pre>Old: 422221 GTAGGCAAAAAAGACAAGATGGAAATCATTGGGCCGTTATAAATTTGCTTGTAGAAAATT 422280
||||||||||||||||||||||||||||||||||||||||||||||||||| |||||||
New: 422221 GTAGGCAAAAAAGACAAGATGGAAATCATTGGGCCGTTATAAATTTGCTTGATGAAAATT 422280</pre>
|- style="height:30px; width:30px; text-align:center;"
| 2001-05-29
| [https://www.yeastgenome.org/locus/YBL069W YBL069W]
| 91711
| 91711
| Deletion
| C
|
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II within the ORF AST1/YBL069W. The C at chromosomal coordinate 91711 was deleted, shifting the reading frame and moving the stop from 91722 to 92025:
<pre>Old: 91681 TTGATTCACGGCGGTGGTGCGTACGTAACCCACTGTAGGTGATTACGTTGCCAATTATAA 91740
|||||||||||||||||||||||||||||| |||||||||||||||||||||||||||||
New: 91681 TTGATTCACGGCGGTGGTGCGTACGTAACC-ACTGTAGGTGATTACGTTGCCAATTATAA 91739</pre>
|- style="height:30px; width:30px; text-align:center;"
| 2001-05-29
| [https://www.yeastgenome.org/locus/YBL004W YBL004W]
| 234918
| 234918
| Substitution
| C
| A
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II within the ORF UTP20/YBL004W. The C at chromosomal coordinate 234918 was changed to an A:
<pre>Old: 234901 CAGACCGTATTAGAAAGCAGAAAGGAAAGGAGATCTAAAAGGGCAATTCTGGCTGTTAAC 234960
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
New: 234901 CAGACCGTATTAGAAAGAAGAAAGGAAAGGAGATCTAAAAGGGCAATTCTGGCTGTTAAC 234960</pre>
|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 1999-04-26
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR266C YBR266C], [https://www.yeastgenome.org/locus/YBR267W YBR267W]
| 739912
| 739912
| Deletion
| A
|
|- style="height:30px; width:30px; text-align:center;"
| 739866
| 739866
| Deletion
| G
|
|-
| || colspan="6" | Two changes were made to the systematic sequence of Chromosome II within the ORF REI1/YBR267W. The G at chromosomal coordinate 739866 was deleted, and the A at 739912 was deleted; as a result, the start of YBR267W was moved 294 nt upstream.
Note that the deletion at 739912 also affects the overlapping ORF SLM6/YBR266C; as a result, the stop of YBR266C was moved 111 nt upstream:
<pre>Old: 739860 GAGCAGGCGGGCCCACATGAAGTCCGATTGGCATCGCTACAATTTGAAAAGAACGTGTTG 739919
|||||| ||||||||||||||||||||||||||||||||||||||||||||| |||||||
New: 739860 GAGCAG-CGGGCCCACATGAAGTCCGATTGGCATCGCTACAATTTGAAAAGA-CGTGTTG 739917</pre>
|- style="height:30px; width:30px; text-align:center;"
| 1999-04-26
| [https://www.yeastgenome.org/locus/YBR201W YBR201W]
| 623651
| 623651
| Deletion
| A
|
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II in the region upstream of the ORF DER1/YBR201W. The A at chromosomal coordinate 623651 was deleted. As a result, the start of YBR201W was moved upstream 210 nucleotides, increasing the size of the predicted protein from 141 to 211 amino acids.
<pre>Old: 623640 GATCCAGGGAAAGGTAGTGTACAGTTATGATTTAGTATTCAAAAAGGGACAATATGGAAG 623699
||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||
New: 623640 GATCCAGGGAA-GGTAGTGTACAGTTATGATTTAGTATTCAAAAAGGGACAATATGGAAG 623698</pre>
|- style="height:30px; width:30px; text-align:center;"
| 1999-04-26
| [https://www.yeastgenome.org/locus/YBR294W YBR294W]
| 791709
| 791709
| Substitution
| T
| C
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II within the ORF SUL1/YBR294W. The T at chromosomal coordinate 791709 was changed to a C:
<pre>Old: 791700 TATGTGCTGTAACTGGGACAAATTTACCGTTTTTTCATATCGATATACCCGATTTTTCTA 791759
||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||||
New: 791700 TATGTGCTGCAACTGGGACAAATTTACCGTTTTTTCATATCGATATACCCGATTTTTCTA 791759</pre>
|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 1999-04-26
| rowspan="3"| [https://www.yeastgenome.org/locus/YBR069C YBR069C], [https://www.yeastgenome.org/locus/YBR070C YBR070C]
| 378824
| 378824
| Insertion
|
| C
|- style="height:30px; width:30px; text-align:center;"
| 378810
| 378810
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 378815
| 378815
| Deletion
| C
|
|-
| || colspan="6" | Three changes were made to the systematic sequence of Chromosome II in the intergenic region between the ORFs TAT1/YBR069C and ALG14/YBR070C. A single T was inserted after the T at chromosomal coordinate 378810, the C at 378815 was deleted, and a C was inserted after the G at 378824:
<pre>Old: 378781 GCCGGCCCTGACTGACCTTTTTTGTATTTT-GGCCCGTCCCGGCG-GGCGAAGAGTGAGAC 378839
|||||||||||||||||||||||||||||| |||| ||||||||| |||||||||||||||
New: 378781 GCCGGCCCTGACTGACCTTTTTTGTATTTTTGGCC-GTCCCGGCGCGGCGAAGAGTGAGAC 378840</pre>
|- style="height:30px; width:30px; text-align:center;"
| 1999-04-23
| [https://www.yeastgenome.org/locus/YBL067C YBL067C]
| 94040
| 94040
| Substitution
| G
| C
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II within the ORF UBP13/YBL067C. The G at chromosomal coordinate 94040 was changed to a C:
<pre>Old: 94021 CATAATGGCCGTGTTGTGGGCCACCGCCCATATGAACGACAATCCCAGCCAATTCATACT 94080
||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||
New: 94021 CATAATGGCCGTGTTGTGGCCCACCGCCCATATGAACGACAATCCCAGCCAATTCATACT 94080</pre>
|- style="height:30px; width:30px; text-align:center;"
| rowspan="4"| 1999-04-23
| rowspan="4"| [https://www.yeastgenome.org/locus/YBR006W YBR006W]
| 247367
| 247367
| Substitution
| C
| T
|- style="height:30px; width:30px; text-align:center;"
| 248539
| 248539
| Substitution
| A
| T
|- style="height:30px; width:30px; text-align:center;"
| 248278
| 248278
| Substitution
| A
| T
|- style="height:30px; width:30px; text-align:center;"
| 247262
| 247262
| Substitution
| C
| G
|-
| || colspan="6" | Three single nucleotide (nt) substitutions were made to the systematic sequence of Chromosome II within the ORF UGA2/YBR006W, and one substitution was made in the adjacent intergenic region. The C at chromosomal coordinate 247262 was changed to a G, the C at 247367 was changed to a T, the A at 248278 was changed to a T (destroying the stop codon), and the A at 248539 was changed to a T. As a result, the stop was moved 186 nucleotides downstream, increasing the size of the coding sequence from 1308 nt to 1494 nt.
<pre>Old: 247261 TCGCAACCATCATTACTTTAGAAAATGGTAAAGCTCTAGGGGAAGCTAAAGGAGAAATCA 247320
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
New: 247261 TGGCAACCATCATTACTTTAGAAAATGGTAAAGCTCTAGGGGAAGCTAAAGGAGAAATCA 247320
Old: 247321 AATACGCGGCTTCGTATTTTGAGTGGTACGCCGAGGAAGCACCCCGCTTATATGGTGCTA 247380
|||||||||||||||||||||||||||||||||||||||||||||| |||||||||||||
New: 247321 AATACGCGGCTTCGTATTTTGAGTGGTACGCCGAGGAAGCACCCCGTTTATATGGTGCTA 247380
Old: 248221 CTAATGATACTGAGTTTGGTTTAGCAGCATATGTCTTTTCTAAAAATGTCAACACTTAAT 248280
||||||||||||||||||||||||||||||||||||||||||||||||||||||||| ||
New: 248221 CTAATGATACTGAGTTTGGTTTAGCAGCATATGTCTTTTCTAAAAATGTCAACACTTTAT 248280
Old: 248521 GTATATATCTATTGCATGAATAAATACTCTACTCCTCGTATATAGAAAGTTAAGTAAATT 248580
|||||||||||||||||| |||||||||||||||||||||||||||||||||||||||||
New: 248521 GTATATATCTATTGCATGTATAAATACTCTACTCCTCGTATATAGAAAGTTAAGTAAATT 248580</pre>
|- style="height:30px; width:30px; text-align:center;"
| 1999-04-23
| [https://www.yeastgenome.org/locus/YBL066C YBL066C]
| 97484
| 97485
| Substitution
| TG
| GC
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II within the ORF SEF1/YBL066C. The two nucleotides TG at positions 575 and 576 (chromosomal coordinates 97484-97485) were changed to GC, altering translation by changing amino acid 192 from Gln (CAA) to Ala (GCA). Note that this ORF is on the Crick strand.
<pre>Old: 97441 AGAACCGTCAGAATCTCCGTTATTTGTCTTGGCTAGCTTTTCTTGCTGCTTTAAGGCATT 97500
||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
New: 97441 AGAACCGTCAGAATCTCCGTTATTTGTCTTGGCTAGCTTTTCTGCCTGCTTTAAGGCATT 97500</pre>
'''Cherry JM, et al.''' (1998) "Genetic and Physical Maps of Saccharomyces cerevisiae (Edition 15)". Pp. 414-420 in 1998 Yeast Genetics and Molecular Biology Meeting Program and Abstracts. Bethesda, MD: The Genetics Society of America 
[https://www.yeastgenome.org/reference/S000076263 SGD paper]

|- style="height:30px; width:30px; text-align:center;"
| 1999-04-22
| [https://www.yeastgenome.org/locus/YBL033C YBL033C]
| 159114
| 159114
| Substitution
| C
| G
|-
| || colspan="6" | The C at chromosomal coordinate 159114 within the ORF RIB1/YBL033C was changed to a G, altering translation by changing amino acid 181 from Lys (AAG) to Asn (AAC). Note that this ORF is on the Crick strand:
<pre>Old: 159061 CGACCCTCTTGTCTTAGATACACGATAACACCATGGCCGTTTCCACCTTTGATCTTGCTT 159120
||||||||||||||||||||||||||||||||||||||||||||||||||||| ||||||
New: 159061 CGACCCTCTTGTCTTAGATACACGATAACACCATGGCCGTTTCCACCTTTGATGTTGCTT 159120</pre>
'''Cherry JM, et al.''' (1998) "Genetic and Physical Maps of Saccharomyces cerevisiae (Edition 15)". Pp. 414-420 in 1998 Yeast Genetics and Molecular Biology Meeting Program and Abstracts. Bethesda, MD: The Genetics Society of America 
[https://www.yeastgenome.org/reference/S000076263 SGD paper]

|- style="height:30px; width:30px; text-align:center;"
| rowspan="6"| 1998-09-13
| rowspan="6"| [https://www.yeastgenome.org/locus/YBL101C YBL101C]
| 25408
| 25408
| Insertion
|
| C
|- style="height:30px; width:30px; text-align:center;"
| 28272
| 28272
| Insertion
|
| G
|- style="height:30px; width:30px; text-align:center;"
| 28296
| 28296
| Insertion
|
| C
|- style="height:30px; width:30px; text-align:center;"
| 25394
| 25394
| Deletion
| T
|
|- style="height:30px; width:30px; text-align:center;"
| 28306
| 28306
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 28302
| 28302
| Insertion
|
| GG
|-
| || colspan="6" | Six changes were made to the systematic sequence of Chromosome II within the ORF ECM21/YBL101C and in the adjacent intergenic region. Within the ORF, the T at chromosomal coordinate 25394 was deleted, and a single C was inserted after the C at 25408:
<pre>Old: 25381 CGGCATCATCGCTTGTATCCGGATGGCC-ACTAACTGACGTAGTTCTTGATAAGTTCAAT 25439
||||||||||||| |||||||||||||| |||||||||||||||||||||||||||||||
New: 25381 CGGCATCATCGCT-GTATCCGGATGGCCCACTAACTGACGTAGTTCTTGATAAGTTCAAT 25439</pre>
Upstream of the ORF, a single G was inserted after the G at 28272, a single C was inserted after the C at 28296, two nucleotides (nt) GG were inserted after the G at 28302, and the A at 28306 was changed to a G:
<pre>Old: 28260 TTTTTCGCCACCG-TCTTGATGTTATAAACGGCATGCC-AATAGG--TAGAGAAAAATCT 28315
||||||||||||| |||||||||||||||||||||||| |||||| ||| |||||||||
New: 28260 TTTTTCGCCACCGGTCTTGATGTTATAAACGGCATGCCCAATAGGGGTAGGGAAAAATCT 28319</pre>
The start site of YBL101C was then moved upstream, extending the size of the coding region from 3234 nt to 3354 nt, and the size of the predicted protein from 728 amino acids (aa) to 754 aa.

|- style="height:30px; width:30px; text-align:center;"
| 1997-07-27
| [https://www.yeastgenome.org/locus/YBL091C YBL091C]
| 48615
| 48615
| Substitution
| A
| C
|-
| || colspan="6" | The A at chromosomal coordinate 48615 (upstream of the Crick strand ORF MAP2/YBL091C at coordinates 48402-47353) was changed to a C, and the start site of YBL091C was then moved 216 nucleotides (nt) upstream to the newly-created start codon, extending the size of the coding sequence from 1050 nt to 1266 nt, the size of the predicted protein from 349 amino acids (aa) to 421 aa. Note that the sequence presented below is from the Watson strand:
<pre>New: 48600 TATTTCAGCGTCTGTCATTTTTCAATACGGTAGAGCTTCTACAGTACTTGTTGATGTAAA 48659
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Old: 48600 TATTTCAGCGTCTGTAATTTTTCAATACGGTAGAGCTTCTACAGTACTTGTTGATGTAAA 48659</pre>
|- style="height:30px; width:30px; text-align:center;"
| 1997-07-27
| [https://www.yeastgenome.org/locus/YBL103C YBL103C]
| 22603
| 22603
| Insertion
|
| G
|-
| || colspan="6" | A single G was inserted after the G at chromosomal coordinate 22603 within the ORF RTG3/YBL103C, shifting the frame and extending the 3' end by 510 nucleotides:
<pre>New: 22561 TACCTAGGTCATCGTAATTCAATAAAGATGGTGGAACCAACTGGCCGAGTTCTTTTATCT 22620
||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||
Old: 22561 TACCTAGGTCATCGTAATTCAATAAAGATGGTGGAACCAACTG-CCGAGTTCTTTTATCT 22619</pre>
|}

=Annotation Changes ''without sequence changes''=
{| border="1" style="border-collapse:collapse; width:90%" cellpadding="6"
! Date !! Affected Features
|-
| 2014-11-18|| [https://www.yeastgenome.org/locus/TLC1 TLC1] 
The feature_type annotation of [https://www.yeastgenome.org/locus/TLC1 TLC1] was changed from ncRNA to telomerase_RNA_gene (SO:0001643) as part of SGD's genome annotation revision R64.2.
|-
| 2014-11-18|| [https://www.yeastgenome.org/locus/ARS207 ARS207], [https://www.yeastgenome.org/locus/ARS208 ARS208], [https://www.yeastgenome.org/locus/ARS209 ARS209], [https://www.yeastgenome.org/locus/ARS211 ARS211], [https://www.yeastgenome.org/locus/ARS214 ARS214], [https://www.yeastgenome.org/locus/ARS216 ARS216], [https://www.yeastgenome.org/locus/ARS217 ARS217], [https://www.yeastgenome.org/locus/ARS224 ARS224], [https://www.yeastgenome.org/locus/ARS231 ARS231] 
As part of SGD's genome annotation revision R64.2, new ARS consensus sequences were annotated within the following ARS elements on Chromosome II based on Liachko et al. 2013: [https://www.yeastgenome.org/locus/ARS207 ARS207], [https://www.yeastgenome.org/locus/ARS231 ARS231], [https://www.yeastgenome.org/locus/ARS208 ARS208], [https://www.yeastgenome.org/locus/ARS209 ARS209], [https://www.yeastgenome.org/locus/ARS211 ARS211], [https://www.yeastgenome.org/locus/ARS214 ARS214], [https://www.yeastgenome.org/locus/ARS216 ARS216], [https://www.yeastgenome.org/locus/ARS217 ARS217], [https://www.yeastgenome.org/locus/ARS224 ARS224]. 
'''Liachko I, et al.''' (2013) High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast. Genome Res 23(4):698-704. 
[https://www.yeastgenome.org/reference/S000152760 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/23241746 PubMed] | [https://genome.cshlp.org/content/23/4/698 Full-Text]
|-
| 2014-11-18|| [https://www.yeastgenome.org/locus/ARS202 ARS202], [https://www.yeastgenome.org/locus/ARS207 ARS207], [https://www.yeastgenome.org/locus/ARS208 ARS208], [https://www.yeastgenome.org/locus/ARS209 ARS209], [https://www.yeastgenome.org/locus/ARS214 ARS214], [https://www.yeastgenome.org/locus/ARS224 ARS224], [https://www.yeastgenome.org/locus/ARS228 ARS228], [https://www.yeastgenome.org/locus/ARS231 ARS231] 
The chromosomal coordinates of the following ARS elements on Chromosome II were updated based on Liachko et al. 2013 as part of SGD's genome annotation revision R64.2: [https://www.yeastgenome.org/locus/ARS202 ARS202], [https://www.yeastgenome.org/locus/ARS207 ARS207], [https://www.yeastgenome.org/locus/ARS231 ARS231], [https://www.yeastgenome.org/locus/ARS208 ARS208], [https://www.yeastgenome.org/locus/ARS209 ARS209], [https://www.yeastgenome.org/locus/ARS214 ARS214], [https://www.yeastgenome.org/locus/ARS224 ARS224], [https://www.yeastgenome.org/locus/ARS228 ARS228]. 
'''Liachko I, et al.''' (2013) High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast. Genome Res 23(4):698-704. 
[https://www.yeastgenome.org/reference/S000152760 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/23241746 PubMed] | [https://genome.cshlp.org/content/23/4/698 Full-Text]
|-
| 2014-11-18|| [https://www.yeastgenome.org/locus/ARS200 ARS200], [https://www.yeastgenome.org/locus/ARS201 ARS201], [https://www.yeastgenome.org/locus/ARS203 ARS203], [https://www.yeastgenome.org/locus/ARS206 ARS206], [https://www.yeastgenome.org/locus/ARS217 ARS217] 
The following new ARS elements on Chromosome II were added to the genome annotation based on Liachko et al. 2013 as part of SGD's genome annotation revision R64.2: [https://www.yeastgenome.org/locus/ARS200 ARS200], [https://www.yeastgenome.org/locus/ARS201 ARS201], [https://www.yeastgenome.org/locus/ARS203 ARS203], [https://www.yeastgenome.org/locus/ARS206 ARS206], [https://www.yeastgenome.org/locus/ARS217 ARS217]. 
'''Liachko I, et al.''' (2013) High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast. Genome Res 23(4):698-704. 
[https://www.yeastgenome.org/reference/S000152760 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/23241746 PubMed] | [https://genome.cshlp.org/content/23/4/698 Full-Text]
|-
| 2014-11-18|| [https://www.yeastgenome.org/locus/ETC8 ETC8] 
The following previously unmapped features were identified as nuclear matrix attachment sites and assigned chromosomal coordinates based on Hiraga et al. 2012 as part of SGD's genome annotation revision R64.2: [https://www.yeastgenome.org/locus/ETC1 ETC1], [https://www.yeastgenome.org/locus/ETC2 ETC2], [https://www.yeastgenome.org/locus/ETC3 ETC3], [https://www.yeastgenome.org/locus/ETC4 ETC4], [https://www.yeastgenome.org/locus/ETC6 ETC6], [https://www.yeastgenome.org/locus/ETC7 ETC7], [https://www.yeastgenome.org/locus/ETC8 ETC8]. 
'''Hiraga SI, et al.''' (2012) TFIIIC localizes budding yeast ETC sites to the nuclear periphery. Mol Biol Cell 23(14):2741-54 
[https://www.yeastgenome.org/reference/S000149071 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/22496415 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395662 Full-Text]
|-
| 2009-05-07|| [https://www.yeastgenome.org/locus/YBR073W YBR073W] 
The start site for [https://www.yeastgenome.org/locus/RDH54 RDH54]/[https://www.yeastgenome.org/locus/YBR073W YBR073W] was reinstated 102 nt (34 codons) upstream. This is a reversal of the start site change made to this ORF on 2003-09-22. Thank you to Nancy Hollingsworth for bringing this issue to our attention. 
'''Shinohara M, et al.''' (1997) Characterization of the roles of the Saccharomyces cerevisiae RAD54 gene and a homologue of RAD54, RDH54/TID1, in mitosis and meiosis. Genetics 147(4):1545-56 
[https://www.yeastgenome.org/reference/S000041992 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/9409820 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1208330 Full-Text] 
'''Petukhova G, et al.''' (2000) Promotion of Rad51-dependent D-loop formation by yeast recombination factor Rdh54/Tid1. Genes Dev 14(17):2206-15 
[https://www.yeastgenome.org/reference/S000046962 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/10970884 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC316899 Full-Text] 
'''Chi P, et al.''' (2006) Yeast recombination factor Rdh54 functionally interacts with the Rad51 recombinase and catalyzes Rad51 removal from DNA. J Biol Chem 281(36):26268-79 
[https://www.yeastgenome.org/reference/S000117052 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/16831867 Pubmed] | [http://www.jbc.org/content/281/36/26268.long Full-Text]
'''Kwon Y, et al.''' (2008) ATP-dependent Chromatin Remodeling by the Saccharomyces cerevisiae Homologous Recombination Factor Rdh54. J Biol Chem 283(16):10445-52 
[https://www.yeastgenome.org/reference/S000125605 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/18292093 Pubmed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447626/ Full-Text]

|-
| 2009-05-07|| [https://www.yeastgenome.org/locus/ARS212 ARS212], [https://www.yeastgenome.org/locus/ARS213 ARS213], [https://www.yeastgenome.org/locus/ARS221 ARS221] 
The following ARS elements on Chromosome 2 were added to the genome annotation based on Raveendranathan et al. 2006: [https://www.yeastgenome.org/locus/ARS212 ARS212], [https://www.yeastgenome.org/locus/ARS213 ARS213], and [https://www.yeastgenome.org/locus/ARS221 ARS221]. 
'''Raveendranathan M, et al.''' (2006) Genome-wide replication profiles of S-phase checkpoint mutants reveal fragile sites in yeast. EMBO J 25(15):3627-39 
[https://www.yeastgenome.org/reference/S000117571 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/16888628 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538557 Full-Text]

|-
| 2007-07-09|| [https://www.yeastgenome.org/locus/YBR215W YBR215W] 
The start of ORF [https://www.yeastgenome.org/locus/HPC2 HPC2]/[https://www.yeastgenome.org/locus/YBR215W YBR215W] was moved 90 nt upstream and an intron was added at relative coordinates 14..97 based on GenBank EF123149 and Juneau et al. 2007. According to Juneau et al. 2007, the intron is "inefficiently spliced" (splicing rate 85%). The ORF had been annotated as 1872 nt long, but is now 1962 nt in length. 
'''Juneau K, et al.''' (2007) High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing. Proc Natl Acad Sci U S A 104(5):1522-7 
[https://www.yeastgenome.org/reference/S000120506 SGD paper] | [https://www.yeastgenome.org/reference/S000120506 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1780280 Full-Text] | [http://yfgdb.princeton.edu/cgi-bin/display.cgi?id=17244705&db=pmid YFGdb] 
|-
| 2007-04-05|| [https://www.yeastgenome.org/locus/YBLCdelta7 YBLCdelta7], [https://www.yeastgenome.org/locus/YBRCdelta11 YBRCdelta11], [https://www.yeastgenome.org/locus/YBRCdelta14 YBRCdelta14], [https://www.yeastgenome.org/locus/YBRCdelta19 YBRCdelta19] 
The following Ty1 LTRs on Chromosome II were mistakenly annotated on the wrong strand (i.e., on Watson instead of Crick); the error has now been corrected, so that the LTRs are annotated on the Crick strand: [https://www.yeastgenome.org/locus/YBLCdelta7 YBLCdelta7], [https://www.yeastgenome.org/locus/YBRCdelta11 YBRCdelta11], [https://www.yeastgenome.org/locus/YBRCdelta14 YBRCdelta14], [https://www.yeastgenome.org/locus/YBRCdelta19 YBRCdelta19]. 
|-
| 2007-04-05|| [https://www.yeastgenome.org/locus/YBRCtau2 YBRCtau2] 
[https://www.yeastgenome.org/locus/YBRWtau2 YBRWtau2], a Ty4 LTR on Chromosome II, was mistakenly annotated on the wrong strand (i.e., on Watson instead of Crick). Both the orientation and the feature name have been corrected, so that the LTR now has the systematic name [https://www.yeastgenome.org/locus/YBRCtau2 YBRCtau2] and is annotated on the Crick strand. The name [https://www.yeastgenome.org/locus/YBRWtau2 YBRWtau2] is being retained as an alias. 
|-
| 2007-04-05|| [https://www.yeastgenome.org/locus/YBLCtau1 YBLCtau1] 
[https://www.yeastgenome.org/locus/YBLWtau1 YBLWtau1], a Ty4 LTR on Chromosome II, was mistakenly annotated on the wrong strand (i.e., on Watson instead of Crick). Both the orientation and the feature name have been corrected, so that the LTR now has the systematic name [https://www.yeastgenome.org/locus/YBLCtau1 YBLCtau1] and is annotated on the Crick strand. The name [https://www.yeastgenome.org/locus/YBLWtau1 YBLWtau1] is being retained as an alias. 
|-
| 2007-04-04|| [https://www.yeastgenome.org/locus/YBR089C-A YBR089C-A] 
[https://www.yeastgenome.org/locus/NHP6B NHP6B]/[https://www.yeastgenome.org/locus/YBR089C-A YBR089C-A] mRNA contains an intron in the 5' untranslated region (UTR). 
'''Miura F, et al.''' (2006) A large-scale full-length cDNA analysis to explore the budding yeast transcriptome. Proc Natl Acad Sci U S A 103(47):17846-51 
[https://www.yeastgenome.org/reference/S000119659 SGD papers] | [https://www.ncbi.nlm.nih.gov/pubmed/17101987 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1693835/ Full-Text] | [https://www.pnas.org/content/suppl/2006/11/14/0605645103.DC1 Web Supplement] | [http://yfgdb.princeton.edu/cgi-bin/display.cgi?id=17101987&db=pmid YFGdb] 
'''Juneau K, et al.''' (2007) High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing. Proc Natl Acad Sci U S A 104(5):1522-7 
[https://www.yeastgenome.org/reference/S000120506 SGD paper] | [https://www.yeastgenome.org/reference/S000120506 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1780280 Full-Text] | [http://yfgdb.princeton.edu/cgi-bin/display.cgi?id=17244705&db=pmid YFGdb] 
|-
| 2007-04-04|| [https://www.yeastgenome.org/locus/YBL092W YBL092W] 
[https://www.yeastgenome.org/locus/RPL32 RPL32]/[https://www.yeastgenome.org/locus/YBL092W YBL092W] mRNA contains an intron in the 5' untranslated region (UTR). 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 
'''Miura F, et al.''' (2006) A large-scale full-length cDNA analysis to explore the budding yeast transcriptome. Proc Natl Acad Sci U S A 103(47):17846-51 
[https://www.yeastgenome.org/reference/S000119659 SGD papers] | [https://www.ncbi.nlm.nih.gov/pubmed/17101987 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1693835/ Full-Text] | [https://www.pnas.org/content/suppl/2006/11/14/0605645103.DC1 Web Supplement] | [http://yfgdb.princeton.edu/cgi-bin/display.cgi?id=17101987&db=pmid YFGdb] 
'''Juneau K, et al.''' (2007) High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing. Proc Natl Acad Sci U S A 104(5):1522-7 
[https://www.yeastgenome.org/reference/S000120506 SGD paper] | [https://www.yeastgenome.org/reference/S000120506 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1780280 Full-Text] | [http://yfgdb.princeton.edu/cgi-bin/display.cgi?id=17244705&db=pmid YFGdb] 

|-
| 2007-04-04|| [https://www.yeastgenome.org/locus/YBL072C YBL072C] 
[https://www.yeastgenome.org/locus/RPS8A RPS8A]/[https://www.yeastgenome.org/locus/YBL072C YBL072C] mRNA contains an intron in the 5' untranslated region (UTR). 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 
'''Miura F, et al.''' (2006) A large-scale full-length cDNA analysis to explore the budding yeast transcriptome. Proc Natl Acad Sci U S A 103(47):17846-51 
[https://www.yeastgenome.org/reference/S000119659 SGD papers] | [https://www.ncbi.nlm.nih.gov/pubmed/17101987 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1693835/ Full-Text] | [https://www.pnas.org/content/suppl/2006/11/14/0605645103.DC1 Web Supplement] | [http://yfgdb.princeton.edu/cgi-bin/display.cgi?id=17101987&db=pmid YFGdb] 
'''Juneau K, et al.''' (2007) High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing. Proc Natl Acad Sci U S A 104(5):1522-7 
[https://www.yeastgenome.org/reference/S000120506 SGD paper] | [https://www.yeastgenome.org/reference/S000120506 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1780280 Full-Text] | [http://yfgdb.princeton.edu/cgi-bin/display.cgi?id=17244705&db=pmid YFGdb] 

|-
| 2006-10-04|| [https://www.yeastgenome.org/locus/LSR1 LSR1] 
The start site and the stop site for [https://www.yeastgenome.org/locus/LSR1 LSR1]/[https://www.yeastgenome.org/locus/snR20 snR20] (aka U2 snRNA) were each moved 4 nt upstream, to the positions determined by Ares M. Jr. (1986). Thanks to Wayne Decatur for bringing this update to our attention. 
'''Ares M Jr''' (1986) U2 RNA from yeast is unexpectedly large and contains homology to vertebrate U4, U5, and U6 small nuclear RNAs. Cell 47(1):49-59 
[https://www.yeastgenome.org/reference/S000043315 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/3530502 PubMed] | [https://www.sciencedirect.com/science/article/pii/009286748690365X?via%3Dihub Full-Text]

|-
| 2006-10-02|| [https://www.yeastgenome.org/locus/ARS230 ARS230], [https://www.yeastgenome.org/locus/ARS231 ARS231] 
[https://www.yeastgenome.org/locus/ARS230 ARS230] (also known as [https://www.yeastgenome.org/locus/ARS201 ARS201].5) and [https://www.yeastgenome.org/locus/ARS231 ARS231] (also known as [https://www.yeastgenome.org/locus/ARS207 ARS207].5) were added to the genome annotation based on Nieduszynski et al. 2006. 
'''Nieduszynski CA, et al.''' (2006) Genome-wide identification of replication origins in yeast by comparative genomics. Genes Dev 20(14):1874-9 
[https://www.yeastgenome.org/reference/S000117321 SGD papers] | [https://www.ncbi.nlm.nih.gov/pubmed/16847347 PubMed Entry] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1522085 Full-Text] | [http://genesdev.cshlp.org/content/20/14/1874/suppl/DC1 Web Supplement]

|-
| 2006-09-07|| [https://www.yeastgenome.org/locus/ARS202 ARS202], [https://www.yeastgenome.org/locus/ARS207 ARS207], [https://www.yeastgenome.org/locus/ARS208 ARS208], [https://www.yeastgenome.org/locus/ARS211 ARS211], [https://www.yeastgenome.org/locus/ARS214 ARS214], [https://www.yeastgenome.org/locus/ARS215 ARS215], [https://www.yeastgenome.org/locus/ARS216 ARS216], [https://www.yeastgenome.org/locus/ARS220 ARS220], [https://www.yeastgenome.org/locus/ARS222 ARS222], [https://www.yeastgenome.org/locus/ARS224 ARS224], [https://www.yeastgenome.org/locus/ARS225 ARS225], [https://www.yeastgenome.org/locus/ARS228 ARS228] 
The following ARS elements on Chromosome II were added to SGD based on Nieduszynski et al. 2006: [https://www.yeastgenome.org/locus/ARS202 ARS202], [https://www.yeastgenome.org/locus/ARS207 ARS207], [https://www.yeastgenome.org/locus/ARS208 ARS208], [https://www.yeastgenome.org/locus/ARS211 ARS211], [https://www.yeastgenome.org/locus/ARS214 ARS214], [https://www.yeastgenome.org/locus/ARS215 ARS215], [https://www.yeastgenome.org/locus/ARS216 ARS216], [https://www.yeastgenome.org/locus/ARS220 ARS220], [https://www.yeastgenome.org/locus/ARS222 ARS222], [https://www.yeastgenome.org/locus/ARS224 ARS224], [https://www.yeastgenome.org/locus/ARS225 ARS225], [https://www.yeastgenome.org/locus/ARS228 ARS228]. 
'''Nieduszynski CA, et al.''' (2006) Genome-wide identification of replication origins in yeast by comparative genomics. Genes Dev 20(14):1874-9 
[https://www.yeastgenome.org/reference/S000117321 SGD papers] | [https://www.ncbi.nlm.nih.gov/pubmed/16847347 PubMed Entry] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1522085 Full-Text] | [http://genesdev.cshlp.org/content/20/14/1874/suppl/DC1 Web Supplement]

|-
| 2006-03-02|| [https://www.yeastgenome.org/locus/ARS209 ARS209] 
This new ARS element [https://www.yeastgenome.org/locus/ARS209 ARS209] was added to the genome annotation based on Bouton & Smith 1986 and Wyrick et al. 2001. 
'''Wyrick JJ, et al.''' (2001) Genome-wide distribution of ORC and MCM proteins in S. cerevisiae: high-resolution mapping of replication origins. Science 294(5550):2357-60 
[https://www.yeastgenome.org/reference/S000069019 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/11743203 PubMed] | [https://science.sciencemag.org/content/294/5550/2357 Full-Text] | [http://yfgdb.princeton.edu/cgi-bin/display.cgi?id=11743203&db=pmid YFGdb] | [https://www.ncbi.nlm.nih.gov/pubmed/11743187 Comments & Errata] 
'''Bouton AH and Smith MM''' (1986) Fine-structure analysis of the DNA sequence requirements for autonomous replication of Saccharomyces cerevisiae plasmids. Mol Cell Biol 6(7):2354-63 
[https://www.yeastgenome.org/reference/S000114516 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/3023929 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC367788 Full-Text]

|-
| 2005-11-10|| [https://www.yeastgenome.org/locus/snR161 snR161] 
New snoRNA, [https://www.yeastgenome.org/locus/snR161 snR161], added based on the work of Olivas et al. 1997 and Schattner et al. 2004. Note that Olivas et al. refer to this snoRNA as [https://www.yeastgenome.org/locus/RNA161 RNA161]. 
'''Olivas WM, et al.''' (1997) Analysis of the yeast genome: identification of new non-coding and small ORF-containing RNAs. Nucleic Acids Res 25(22):4619-25 
[https://www.yeastgenome.org/reference/S000064699 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/9358174 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC147069 Full-Text] 
'''Schattner P, et al.''' (2004) Genome-wide searching for pseudouridylation guide snoRNAs: analysis of the Saccharomyces cerevisiae genome. Nucleic Acids Res 32(14):4281-96 
[https://www.yeastgenome.org/reference/S000081218 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/15306656 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514388 Full-Text]

|-
| 2005-11-08|| [https://www.yeastgenome.org/locus/YBR056C-B YBR056C-B], [https://www.yeastgenome.org/locus/YBR201C-A YBR201C-A] 
Based on comparisons of the genome sequences of six Saccharomyces species, Cliften et al. 2003 suggested that two new ORFs, [https://www.yeastgenome.org/locus/YBR056C-B YBR056C-B] and [https://www.yeastgenome.org/locus/YBR201C-A YBR201C-A], be added to the S. cerevisiae genome annotation. 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 
|-
| 2005-11-07|| [https://www.yeastgenome.org/locus/YBR286W YBR286W] 
After consultation with MIPS, SGD will incorporate the annotation change suggested by Kellis et al. 2003 for [https://www.yeastgenome.org/locus/APE3 APE3]/[https://www.yeastgenome.org/locus/YBR286W YBR286W]. The start site is being moved 78 nt downstream from chromosomal coordinate 774618 to 774696, resulting in a predicted protein of 537 aa, as opposed to the previously annotated 563 aa. The 1692-nt ORF is now 1614 nt. 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|-
| 2004-10-12|| [https://www.yeastgenome.org/locus/CEN2 CEN2] 
Centromeric DNA elements CDEI, CDEII, and CDEIII were annotated based on Wieland et al. 2001 and Espelin et al. 2003. 
'''Wieland G, et al.''' (2001) Determination of the binding constants of the centromere protein Cbf1 to all 16 centromere DNAs of Saccharomyces cerevisiae. Nucleic Acids Res 29(5):1054-60 
[https://www.yeastgenome.org/reference/S000059647 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/11222754 PubMed] [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC29730 Full-Text] 
'''Espelin CW, et al.''' (2003) Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII. Mol Biol Cell 14(11):4557-68 
[https://www.yeastgenome.org/reference/S000074756 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/13679521 PubMed] [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC266772 Full-Text]

|-
| 2004-04-01|| [https://www.yeastgenome.org/locus/RUF8 RUF8] 
Feature annotation removed per John McCutcheon and Sean Eddy. 
'''McCutcheon JP and Eddy SR''' (2004) Detailed correction to: Computational identification of noncoding RNAs in Saccharomyces cerevisiae by comparative genomics Nucleic Acids Res. 31:4119-4128, 2003 
[https://www.yeastgenome.org/reference/S000175486 SGD paper] | [https://www.yeastgenome.org/sgdpub/mccutcheon_ruf_correction.pdf Web Supplement]

|-
| 2004-04-01|| [https://www.yeastgenome.org/locus/YBR230W-A YBR230W-A] 
ORF identified by John McCutcheon and Sean Eddy. 
'''McCutcheon JP and Eddy SR''' (2003) Computational identification of non-coding RNAs in Saccharomyces cerevisiae by comparative genomics. Nucleic Acids Res 31(14):4119-28 
[https://www.yeastgenome.org/reference/S000074006 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12853629 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165953 Full-Text] | [https://www.yeastgenome.org/reference/S000175486 Comments & Errata] 

|-
| 2004-01-07|| [https://www.yeastgenome.org/locus/YBL091C-A YBL091C-A] 
Based on comparison to related fungi, Brachat et al., Blandin et al., and Cliften et al. all proposed an intron and 5' extension for [https://www.yeastgenome.org/locus/YBL091C-A YBL091C-A]. The resulting ORF is in the same frame with the start codon shifted 316 bp upstream; the protein has a 76-residue extension at the N-terminus. 
'''Blandin G, et al.''' (2000) Genomic exploration of the hemiascomycetous yeasts: 4. The genome of Saccharomyces cerevisiae revisited. FEBS Lett 487(1):31-6 
[https://www.yeastgenome.org/reference/S000065690 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/11152879 PubMed] | [https://febs.onlinelibrary.wiley.com/doi/full/10.1016/S0014-5793%2800%2902275-4 Full-Text] 
'''Brachat S, et al.''' (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45. 
[https://www.yeastgenome.org/reference/S000073670 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12844361 PubMed] | [https://genomebiology.biomedcentral.com/articles/10.1186/gb-2003-4-7-r45 Full-Text] 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 

|-
| 2003-12-17|| [https://www.yeastgenome.org/locus/YBR111W-A YBR111W-A] 
The size of the first intron of [https://www.yeastgenome.org/locus/YBR111W-A YBR111W-A] was increased and a second intron was added on the basis of conserved splice sites predicted by Cliften et al. 2003, as well as subsequent experimental evidence (GenBank AY278445). The chromosomal coordinates of the coding sequence have changed from 462094-462172..462175-462392 to 462094-462164..462245-462384..462455-462534. 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 

|-
| 2003-12-17|| [https://www.yeastgenome.org/locus/YBR255C-A YBR255C-A] 
The boundaries of the intron in ORF [https://www.yeastgenome.org/locus/YBR255C-A YBR255C-A] were shifted by 1 bp on 5' end and 2 bp on 3' end on basis of conserved splice sites in other fungal species as predicted by Blandin et al. 2000. 
'''Blandin G, et al.''' (2000) Genomic exploration of the hemiascomycetous yeasts: 4. The genome of Saccharomyces cerevisiae revisited. FEBS Lett 487(1):31-6 
[https://www.yeastgenome.org/reference/S000065690 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/11152879 PubMed] | [https://febs.onlinelibrary.wiley.com/doi/full/10.1016/S0014-5793%2800%2902275-4 Full-Text] 

|-
| 2003-09-22|| [https://www.yeastgenome.org/locus/YBR280C YBR280C] 
The start site for [https://www.yeastgenome.org/locus/YBR280C YBR280C] was moved 15 nt (5 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine. 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 

|-
| 2003-09-22|| [https://www.yeastgenome.org/locus/YBR172C YBR172C] 
The start site for [https://www.yeastgenome.org/locus/SMY2 SMY2]/[https://www.yeastgenome.org/locus/YBR172C YBR172C] was moved 150 nt (50 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine. 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 

|-
| 2003-09-22|| [https://www.yeastgenome.org/locus/YBL089W YBL089W] 
The start site for [https://www.yeastgenome.org/locus/AVT5 AVT5]/[https://www.yeastgenome.org/locus/YBL089W YBL089W] was moved 150 nt (50 codons) downstream based on the automated comparison of closely related Saccharomyces species by Kellis et al. 2003. The numbering for both the nucleotides in the DNA coding sequence and the amino acids in the predicted protein have been updated. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine. 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 

|-
| 2003-09-22|| [https://www.yeastgenome.org/locus/YBL068W YBL068W] 
The start site for [https://www.yeastgenome.org/locus/PRS4 PRS4]/[https://www.yeastgenome.org/locus/YBL068W YBL068W] was moved 84 nt (28 codons) downstream based on the automated comparison of closely related Saccharomyces species by Kellis et al. 2003. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine. 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 

|-
| 2003-09-22|| [https://www.yeastgenome.org/locus/YBR095C YBR095C] 
The start site for [https://www.yeastgenome.org/locus/YBR095C YBR095C] was moved 69 nt (23 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine. 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 

|-
| 2003-09-22|| [https://www.yeastgenome.org/locus/YBR073W YBR073W] 
The start site for [https://www.yeastgenome.org/locus/RDH54 RDH54]/[https://www.yeastgenome.org/locus/YBR073W YBR073W] was moved 102 nt (34 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine. 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 

|-
| 2003-09-22|| [https://www.yeastgenome.org/locus/YBR058C YBR058C] 
The start site for [https://www.yeastgenome.org/locus/UBP14 UBP14]/[https://www.yeastgenome.org/locus/YBR058C YBR058C] was moved 66 nt (22 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine. 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 

|-
| 2003-09-22|| [https://www.yeastgenome.org/locus/YBR122C YBR122C] 
The start site for [https://www.yeastgenome.org/locus/MRPL36 MRPL36]/[https://www.yeastgenome.org/locus/YBR122C YBR122C] was moved 57 nt (19 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine; 3) The predicted protein translated from the conserved methionine contains a predicted mitochondrial targeting signal sequence (using both MitoProt (MIPS) and Predotar), while the predicted protein translated from the previously annotated S. cerevisiae start codon does not. 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 

|-
| 2003-09-22|| [https://www.yeastgenome.org/locus/YBR264C YBR264C] 
The start site for [https://www.yeastgenome.org/locus/YPT10 YPT10]/[https://www.yeastgenome.org/locus/YBR264C YBR264C] was moved 57 nt (19 codons) downstream based on the automated comparison of closely-related Saccharomyces species by Kellis et al. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine. 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 

|-
| 2003-09-22|| [https://www.yeastgenome.org/locus/YBR263W YBR263W] 
The start site for [https://www.yeastgenome.org/locus/SHM1 SHM1]/[https://www.yeastgenome.org/locus/YBR263W YBR263W] was moved 225 nt (75 codons) downstream based on the automated comparison of closely-related Saccharomyces species by Kellis et al. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine. 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Cliften P, et al.''' (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6. 
[https://www.yeastgenome.org/reference/S000073948 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12775844 PubMed] | [https://science.sciencemag.org/content/301/5629/71.long Full-Text] | [https://science.sciencemag.org/content/suppl/2003/07/03/1084337.DC1 Web Supplement] 

|-
| 2003-09-09|| [https://www.yeastgenome.org/locus/TEL02L TEL02L], [https://www.yeastgenome.org/locus/TEL02R TEL02R] 
The chromosomal locations for the following telomeric elements on Chromosome 2 were generously provided by Ed Louis and Dave Barton (University of Leicester, UK): [https://www.yeastgenome.org/locus/TEL02L TEL02L], [https://www.yeastgenome.org/locus/TEL02L-X TEL02L-X]C, [https://www.yeastgenome.org/locus/TEL02L-X TEL02L-X]R, [https://www.yeastgenome.org/locus/TEL02L-Y TEL02L-Y]P, [https://www.yeastgenome.org/locus/TEL02R TEL02R], [https://www.yeastgenome.org/locus/TEL02R-X TEL02R-X]C, [https://www.yeastgenome.org/locus/TEL02R-X TEL02R-X]R, [https://www.yeastgenome.org/locus/TEL02R-T TEL02R-T]R. 
Note that [https://www.yeastgenome.org/locus/TEL02L TEL02L] does have telomeric repeats ([https://www.yeastgenome.org/locus/TEL02L-T TEL02L-T]R), but they are missing from the genome annotation due to sequencing difficulties encountered during the initial genome sequencing efforts in the 1990s.
|-
| 2003-07-29|| [https://www.yeastgenome.org/locus/YBL039C-A YBL039C-A], [https://www.yeastgenome.org/locus/YBR121C-A YBR121C-A], [https://www.yeastgenome.org/locus/YBR196C-B YBR196C-B], [https://www.yeastgenome.org/locus/YBR221W-A YBR221W-A] 
Thanks to Oshiro et al., Velculescu et al., and Basrai et al. for providing the coordinates of the following four ORFs on Chromosome 2: [https://www.yeastgenome.org/locus/YBL039C-A YBL039C-A], [https://www.yeastgenome.org/locus/YBR121C-A YBR121C-A], [https://www.yeastgenome.org/locus/YBR196C-B YBR196C-B], [https://www.yeastgenome.org/locus/YBR221W-A YBR221W-A]. 
'''Basrai MA, et al.''' (1999) NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae. Mol Cell Biol 19(10):7041-9 
[https://www.yeastgenome.org/reference/S000042214 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/10490641 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC84699 Full-Text] 
'''Velculescu VE, et al.''' (1997) Characterization of the yeast transcriptome. Cell 88(2):243-51. 
[https://www.yeastgenome.org/reference/S000058021 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/9008165 PubMed] | [https://www.sciencedirect.com/science/article/pii/S0092867400818450?via%3Dihub Full-Text] | [http://yfgdb.princeton.edu/cgi-bin/display.cgi?id=9008165&db=pmid YFGdb] 
'''Oshiro G, et al.''' (2002) Parallel identification of new genes in Saccharomyces cerevisiae. Genome Res 12(8):1210-20. 
[https://www.yeastgenome.org/reference/S000073672 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12176929 PubMed] | [https://genome.cshlp.org/content/12/8/1210.long Full-Text] | [https://genome.cshlp.org/content/12/8/1210/suppl/DC1 Web Supplement] | [http://yfgdb.princeton.edu/cgi-bin/display.cgi?id=12176929&db=pmid YFGdb] 

|-
| 2003-07-29|| [https://www.yeastgenome.org/locus/YBR056W-A YBR056W-A], [https://www.yeastgenome.org/locus/YBR109W-A YBR109W-A], [https://www.yeastgenome.org/locus/YBR126W-B YBR126W-B] 
Thanks to MIPS for providing the coordinates of the following three ORFs on Chromosome 2: [https://www.yeastgenome.org/locus/YBR056W-A YBR056W-A], [https://www.yeastgenome.org/locus/YBR109W-A YBR109W-A], [https://www.yeastgenome.org/locus/YBR126W-B YBR126W-B]. 
|-
| 2003-07-29|| [https://www.yeastgenome.org/locus/YBL006W-A YBL006W-A], [https://www.yeastgenome.org/locus/YBL071C-B YBL071C-B], [https://www.yeastgenome.org/locus/YBL100W-C YBL100W-C], [https://www.yeastgenome.org/locus/YBL113W-A YBL113W-A], [https://www.yeastgenome.org/locus/YBR126W-A YBR126W-A], [https://www.yeastgenome.org/locus/YBR131C-A YBR131C-A], [https://www.yeastgenome.org/locus/YBR141W-A YBR141W-A], [https://www.yeastgenome.org/locus/YBR182C-A YBR182C-A], [https://www.yeastgenome.org/locus/YBR223W-A YBR223W-A], [https://www.yeastgenome.org/locus/YBR296C-A YBR296C-A], [https://www.yeastgenome.org/locus/YBR298C-A YBR298C-A] 
Thanks to Kumar et al. for providing the coordinates of the following 11 ORFs on Chromosome 2: [https://www.yeastgenome.org/locus/YBL006W-A YBL006W-A], [https://www.yeastgenome.org/locus/YBL071C-B YBL071C-B], [https://www.yeastgenome.org/locus/YBL101W-C YBL101W-C], [https://www.yeastgenome.org/locus/YBL113W-A YBL113W-A], [https://www.yeastgenome.org/locus/YBR126W-A YBR126W-A], [https://www.yeastgenome.org/locus/YBR131C-A YBR131C-A], [https://www.yeastgenome.org/locus/YBR141W-A YBR141W-A], [https://www.yeastgenome.org/locus/YBR182C-A YBR182C-A], [https://www.yeastgenome.org/locus/YBR223W-A YBR223W-A], [https://www.yeastgenome.org/locus/YBR296C-A YBR296C-A], [https://www.yeastgenome.org/locus/YBR298C-A YBR298C-A]. 
'''Kumar A, et al.''' (2002) An integrated approach for finding overlooked genes in yeast. Nat Biotechnol 20(1):58-63. 
[https://www.yeastgenome.org/reference/S000073673 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/11753363 PubMed] | [https://www.nature.com/articles/nbt0102-58 Full-Text] | [http://yfgdb.princeton.edu/cgi-bin/display.cgi?id=11753363&db=pmid YFGdb] | [https://www.yeastgenome.org/reference/S000141796 Comments & Errata] 

|-
| 2003-07-29|| [https://www.yeastgenome.org/locus/YBL008W-A YBL008W-A], [https://www.yeastgenome.org/locus/YBL068W-A YBL068W-A], [https://www.yeastgenome.org/locus/YBL103C-A YBL103C-A], [https://www.yeastgenome.org/locus/YBR072C-A YBR072C-A], [https://www.yeastgenome.org/locus/YBR076C-A YBR076C-A], [https://www.yeastgenome.org/locus/YBR196C-A YBR196C-A], [https://www.yeastgenome.org/locus/YBR200W-A YBR200W-A] 
Thanks to Kessler et al. for providing the coordinates of the following seven ORFs on Chromosome 2: [https://www.yeastgenome.org/locus/YBL008W-A YBL008W-A], [https://www.yeastgenome.org/locus/YBL068W-A YBL068W-A], [https://www.yeastgenome.org/locus/YBL103C-A YBL103C-A], [https://www.yeastgenome.org/locus/YBR072C-A YBR072C-A], [https://www.yeastgenome.org/locus/YBR076C-A YBR076C-A], [https://www.yeastgenome.org/locus/YBR196C-A YBR196C-A], [https://www.yeastgenome.org/locus/YBR200W-A YBR200W-A]. 
'''Kessler MM, et al.''' (2003) Systematic discovery of new genes in the Saccharomyces cerevisiae genome. Genome Res 13(2):264-71. 
[https://www.yeastgenome.org/reference/S000073671 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12566404 PubMed] | [https://genome.cshlp.org/content/13/2/264.long Full-Text] 

|-
| 2003-07-29|| [https://www.yeastgenome.org/locus/YBL039W-B YBL039W-B], [https://www.yeastgenome.org/locus/YBR111W-A YBR111W-A] 
Thanks to Brachat et al. for providing the coordinates of the following two ORFs on Chromosome 2 based on homology to Ashbya gossypii: [https://www.yeastgenome.org/locus/YBL039W-B YBL039W-B], [https://www.yeastgenome.org/locus/YBR111W-A YBR111W-A]. 
'''Brachat S, et al.''' (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45. 
[https://www.yeastgenome.org/reference/S000073670 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12844361 PubMed] | [https://genomebiology.biomedcentral.com/articles/10.1186/gb-2003-4-7-r45 Full-Text] 

|-
| 2003-03-06|| [https://www.yeastgenome.org/locus/RUF8 RUF8] 
Thanks to John McCutcheon and Sean Eddy for providing the coordinates for the following RNA features: [https://www.yeastgenome.org/locus/SNR82 SNR82], [https://www.yeastgenome.org/locus/SNR83 SNR83], [https://www.yeastgenome.org/locus/SNR84 SNR84], [https://www.yeastgenome.org/locus/RUF4 RUF4], [https://www.yeastgenome.org/locus/RUF5 RUF5]-1, [https://www.yeastgenome.org/locus/RUF5 RUF5]-2, [https://www.yeastgenome.org/locus/RUF6 RUF6], [https://www.yeastgenome.org/locus/RUF7 RUF7], and [https://www.yeastgenome.org/locus/RUF8 RUF8]. 
'''McCutcheon JP and Eddy SR''' (2003) Computational identification of non-coding RNAs in Saccharomyces cerevisiae by comparative genomics. Nucleic Acids Res 31(14):4119-28 
[https://www.yeastgenome.org/reference/S000074006 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12853629 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC165953 Full-Text] | [https://www.yeastgenome.org/reference/S000175486 Comments & Errata] 

|-
| 2001-01-30|| [https://www.yeastgenome.org/locus/YBL071W-A YBL071W-A] 
ORF added based on similarity to an S. pombe gene (information submitted by Valerie Wood). 
|-
| 2000-08-11|| [https://www.yeastgenome.org/locus/YBR089C-A YBR089C-A] 
old name: [https://www.yeastgenome.org/locus/YBR090C-A YBR090C-A]; new name: [https://www.yeastgenome.org/locus/YBR089C-A YBR089C-A]; date: 11/1998; old coord: ChrII 426447 426148; SGDID: S0002157; Name changed due to nomenclature 
|-
| 2000-07-14|| [https://www.yeastgenome.org/locus/YBR186W YBR186W] 
Davis et al. demonstrated an intron and 3' exon in [https://www.yeastgenome.org/locus/PCH2 PCH2]/[https://www.yeastgenome.org/locus/YBR186W YBR186W] that were not previously annotated. The addition of this intron and exon alters the C-terminus of the protein product and increases the protein size from 537 to 564 amino acids. 
'''Davis CA, et al.''' (2000) Test of intron predictions reveals novel splice sites, alternatively spliced mRNAs and new introns in meiotically regulated genes of yeast. Nucleic Acids Res 28(8):1700-6 
[https://www.yeastgenome.org/reference/S000042737 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/10734188 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC102823 Full-Text] 

|-
| 1999-11-17|| [https://www.yeastgenome.org/locus/YBL059C-A YBL059C-A] 
A new ORF, [https://www.yeastgenome.org/locus/YBL059C-A YBL059C-A], was identified from EST analysis (Evan Hurowitz in Pat Brown's lab). 
|-
| 1998-05-21|| [https://www.yeastgenome.org/locus/YBL091C-A YBL091C-A], [https://www.yeastgenome.org/locus/YBL107W-A YBL107W-A] 
The following 27 ORFs were added to the genome annotation based on Velculescu et al. 1997: [https://www.yeastgenome.org/locus/YBL091C-A YBL091C-A], [https://www.yeastgenome.org/locus/YBL107W-A YBL107W-A], [https://www.yeastgenome.org/locus/YCR018C-A YCR018C-A], [https://www.yeastgenome.org/locus/YCR102W-A YCR102W-A], [https://www.yeastgenome.org/locus/YDL130W-A YDL130W-A], [https://www.yeastgenome.org/locus/YDR034C-A YDR034C-A], [https://www.yeastgenome.org/locus/YDR034W-B YDR034W-B], [https://www.yeastgenome.org/locus/YDR363W-A YDR363W-A], [https://www.yeastgenome.org/locus/YDR525W-A YDR525W-A], [https://www.yeastgenome.org/locus/YER048W-A YER048W-A], [https://www.yeastgenome.org/locus/YER091C-A YER091C-A], [https://www.yeastgenome.org/locus/YER138W-A YER138W-A], [https://www.yeastgenome.org/locus/YGR122C-A YGR122C-A], [https://www.yeastgenome.org/locus/YIR020W-B YIR020W-B], [https://www.yeastgenome.org/locus/YKL033W-A YKL033W-A], [https://www.yeastgenome.org/locus/YKL053C-A YKL053C-A], [https://www.yeastgenome.org/locus/YKL162C-A YKL162C-A], [https://www.yeastgenome.org/locus/YLL018C-A YLL018C-A], [https://www.yeastgenome.org/locus/YLR262C-A YLR262C-A], [https://www.yeastgenome.org/locus/YML081C-A YML081C-A], [https://www.yeastgenome.org/locus/YMR046W-A YMR046W-A], [https://www.yeastgenome.org/locus/YMR158C-B YMR158C-B], [https://www.yeastgenome.org/locus/YMR194C-A YMR194C-A], [https://www.yeastgenome.org/locus/YNR032C-A YNR032C-A], [https://www.yeastgenome.org/locus/YOL013W-A YOL013W-A], [https://www.yeastgenome.org/locus/YOR298C-A YOR298C-A], and [https://www.yeastgenome.org/locus/YPR002C-A YPR002C-A]. 
|}

Chromosome II History

2019-10-02T20:49:02Z

Pcng: /* Annotation Changes */

This page lists all sequence and annotation changes that have been made to the Chromosome II systematic reference sequence since its intial release on 1996-07-31. 
*The sequence of Chromosome II has been updated '''192''' times, affecting '''122''' features. 
*The annotation of Chromosome II has been updated '''49''' times, affecting '''88''' features. 
Current and past versions can be obtained from SGD's [https://www.yeastgenome.org/downloads Download site].

__FORCETOC__

=Sequence Changes=

{|border="1" style="border-collapse:collapse; width:90%" cellpadding="6"
! Date !! Affected Features !! Start Coordinate of Change !! End Coordinate of Change !! Type of Change !! Old Sequence !! New Sequence
|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBR068C YBR068C]
| 375081
| 375081
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 375272
| 375272
| Substitution
| T
| A
|- style="height:30px; width:30px; text-align:center;"
| 374011
| 374011
| Substitution
| T
| A
|-
| || colspan="6" | Nucleotide substitutions within the coding region of BAP2/YBR068C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 139 is now Valine rather than Glutamic Acid, and residue 203 is now Tryptophan rather than Glycine.
<pre>New 373969 GAAGTCAAGGTCAATCTTGTCGAGGGGATTTAATAGCGTAAAATCACGGTTGTAAACCAT 374028
||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||
Old 373966 GAAGTCAAGGTCAATCTTGTCGAGGGGATTTAATAGCGTAAAATCTCGGTTGTAAACCAT 374025
New 375049 AAGAATATAAATGTCCGGATTTATTTTATCATTCCAAAATTGAATAGTCATAGACGCGGT 375108
||||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||
Old 375046 AAGAATATAAATGTCCGGATTTATTTTATCATTCCCAAATTGAATAGTCATAGACGCGGT 375105
New 375229 ATAGGTTACCGCCATCTCACCTGCAGCTTGGATCATGAAGTACGTCACGAAAGAAACCAA 375288
|||||||||||||||||||||||||||||||||||||||||||||| |||||||||||||
Old 375226 ATAGGTTACCGCCATCTCACCTGCAGCTTGGATCATGAAGTACGTCTCGAAAGAAACCAA 375285</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR097W YBR097W]
| 439496
| 439496
| Substitution
| T
| G
|- style="height:30px; width:30px; text-align:center;"
| 437344
| 437344
| Substitution
| A
| G
|-
| || colspan="6" | Nucleotide change(s) in the coding region of VPS15/YBR097W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 134 is now Alanine rather than Threonine, and residue 851 is now Arginine rather than Isoleucine.
<pre>New 437325 ATTCATTGCTTTCCAGTTGTTAAATGCATTAAAGGACATTCATAATCTGAATATTGTCCA 437384
||||||||||||||||||||||||| ||||||||||||||||||||||||||||||||||
Old 437319 ATTCATTGCTTTCCAGTTGTTAAATACATTAAAGGACATTCATAATCTGAATATTGTCCA 437378
New 439485 CTTAACTGCTGAAGACAGAAATTGGATTGATAAGTTCCACATTATTGGGCTAACAGAAAA 439544
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 439479 CTTAACTGCTGAAGACATAAATTGGATTGATAAGTTCCACATTATTGGGCTAACAGAAAA 439538</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR045C YBR045C]
| 328382
| 328382
| Insertion
| || T
|-
| || colspan="6" | A single nucleotide was inserted within ORF GIP1/YBR045C, altering its coding sequence. The start, stop, and majority of the reading frame remain the same, but the C-terminus has changed and the annotated protein is now 66 amino acids longer.
<pre>New 328369 CTCAGTCTATAATTTTCTGCTTCATTTCTCTGCCTTTTATACTCTGTATATTGAAAATAA 328428
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Old 328368 CTCAGTCTATAATTT-CTGCTTCATTTCTCTGCCTTTTATACTCTGTATATTGAAAATAA 328426</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR044C YBR044C]
| 324366
| 324366
| Insertion
|
| T
|-
| || colspan="6" | One nucleotide was inserted within ORF TCM62/YBR044C, very near its 3' end, altering its coding sequence. The start, stop, and majority of reading frame remain the same, but the C-terminus is different and the annotated protein sequence is now one amino acid shorter.
<pre>New 324349 TGTGCCGTTCAGGCTTTTTGTATACACATGTGATAATTGTATTACAGCTTGTAAGTAATT 324408
|||||||||||||||||| |||||||||||||||||||||||||||||||||||||||||
Old 324349 TGTGCCGTTCAGGCTTTT-GTATACACATGTGATAATTGTATTACAGCTTGTAAGTAATT 324407</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR007C YBR007C]
| 250403
| 250403
| Substitution
| C
| G
|- style="height:30px; width:30px; text-align:center;"
| 250039
| 250039
| Substitution
| T
| G
|-
| || colspan="6" | Two nucleotide substitutions within the coding region of DSF2/YBR007C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 205 is now Serine rather than Arginine, and residue 327 is now Proline rather than Threonine.
<pre>New 250012 AGACCGTTTAGGAGATGGTTTGATGGGTGTTGTATCACTCTTAGTTAACTTGAGTTTGGA 250071
|||||||||||||||||||||||||| |||||||||||||||||||||||||||||||||
Old 250013 AGACCGTTTAGGAGATGGTTTGATGGTTGTTGTATCACTCTTAGTTAACTTGAGTTTGGA 250072
New 250372 CCTATATTTCTCGAAGTTGAAAGGATTAGGGCTATTTGTGCTTCTATTGCCATTTTCAAG 250431
|||||||||||||||||||||||||||||| |||||||||||||||||||||||||||||
Old 250373 CCTATATTTCTCGAAGTTGAAAGGATTAGGCCTATTTGTGCTTCTATTGCCATTTTCAAG 250432</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBL105C YBL105C]
| 17455
| 17455
| Substitution
| A
| C
|- style="height:30px; width:30px; text-align:center;"
| 15835
| 15835
| Substitution
| T
| C
|- style="height:30px; width:30px; text-align:center;"
| 15332
| 15332
| Substitution
| G
| C
|-
| || colspan="6" | The substitution of three nucleotides within the coding region of PKC1/YBL105C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 81 is now Cysteine rather than Phenylalanine, residue 621 is now Arginine rather than Lysine, and residue 789 is now Alanine rather than Proline.
<pre>New 15301 TGCGGAGATTGTTGATCAGTGGTTCTGGAGGCATGAGTACTTGTAGGAGCCAAGGACACT 15360
||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||||
Old 15301 TGCGGAGATTGTTGATCAGTGGTTCTGGAGGGATGAGTACTTGTAGGAGCCAAGGACACT 15360
New 15791 TAAATTTATTTAGTTTCTCACGCCCGTGCGTTTGTAGTGAAATTCTTTTATCAATAATAG 15850
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 15791 TAAATTTATTTAGTTTCTCACGCCCGTGCGTTTGTAGTGAAATTTTTTTATCAATAATAG 15840
New 17411 CATTTGGCGATTTGGTAGAAAGAAACCCGTATTCCTTCGAATTGCATCGCTCATTATCTT 17470
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 17411 CATTTGGCGATTTGGTAGAAAGAAACCCGTATTCCTTCGAATTGAATCGCTCATTATCTT 17470</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL057C YBL057C]
| 113437
| 113437
| Deletion
| G
|
|-
| || colspan="6" | One nucleotide was deleted within ORF PTH2/YBL057C, near its 5' end, altering its coding sequence. The stop and reading frame remain the same, but the start has been moved 18 nucleotides downstream and the annotated protein sequence is now six amino acids shorter.
<pre>New 113393 ATGGTGTAATTCGAAGAAACTGTCATCTTTTCCATTAAAAAG-ACGTTATCATGTTACTC 113451
|||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 113395 ATGGTGTAATTCGAAGAAACTGTCATCTTTTCCATTAAAAAGGACGTTATCATGTTACTC 113454</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBL068W YBL068W]
| 92918
| 92920
| Deletion
| CCG
|
|- style="height:30px; width:30px; text-align:center;"
| 92916
| 92916
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 92679
| 92679
| Substitution
| C
| A
|-
| || colspan="6" | Two nucleotide substitutions and one trinucleotide deletion were made within the ORF PRS4/YBL068W, altering its coding sequence. The start, stop, and reading frame remain the same, but the annotated protein is now one amino acid shorter.
<pre>New 92637 TTAATGATTTCTTGATGGAATTATTAATTTTAATTCATGCTTGCAAAATTGCATCTGCAA 92696
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 92635 TTAATGATTTCTTGATGGAATTATTAATTTTAATTCATGCTTGCCAAATTGCATCTGCAA 92694
New 92877 ACAACCTATATGCAGAACCAAGTGTTTTAAATTATATTAGAAC---GAAAACAGATTTCG 92933
||||||||||||||||||||||||||||||||||||||||| | ||||||||||||||
Old 92875 ACAACCTATATGCAGAACCAAGTGTTTTAAATTATATTAGAGCCCGGAAAACAGATTTCG 92934</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR078W YBR078W]
| 394727
| 394727
| Insertion
|
| C
|-
| || colspan="6" | One nucleotide was inserted within ORF ECM33/YBR078W, very near its 3' end, altering its coding sequence. The start, stop, and vast majority of reading frame remain the same, but the C-terminus is different and the annotated protein sequence is now 39 amino acids shorter.
<pre>New 394715 TGCTGCTGTTGGCGTTGCCTTACTATAAGATTAAAGCAACAATTTGTGTTTCTATTATTA 394774
|||||||||||||||||| |||||||||||||||||||||||||||||||||||||||||
Old 394710 TGCTGCTGTTGGCGTTGC-TTACTATAAGATTAAAGCAACAATTTGTGTTTCTATTATTA 394768</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR076W YBR076W]
| 391277
| 391277
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 390442
| 390442
| Deletion
| G
|
|-
| || colspan="6" | A single G nucleotide was deleted near the 3' end, and a single A nucleotide was inserted near the 5' end of ORF ECM8/YBR076W, altering its coding sequence. The ORF was extended 49 amino acids at the N-terminus and shortened 34 amino acids at the C-terminus, resulting in a protein that is 15 amino acids larger. Although this protein is altered at both ends, the central portion of the protein remains the same.
<pre>New 390408 AAACCATCAAGAACAAAATATTCCCACAAAGGAAAATATT-CAACGATAGCGAAAATTTT 390466
|||||||||||||||||||||||||||||||||||||||| |||||||||||||||||||
Old 390402 AAACCATCAAGAACAAAATATTCCCACAAAGGAAAATATTGCAACGATAGCGAAAATTTT 390461
New 391247 CGAACGAAATGTTTATATGTCCAAGTTATAACAAAAAGCAATTGATTGTGTACGCAAGAT 391306
|||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
Old 391242 CGAACGAAATGTTTATATGTCCAAGTTATAACAAAA-GCAATTGATTGTGTACGCAAGAT 391300</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR137W YBR137W]
| 513365
| 513365
| Substitution
| A
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of YBR137W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 110 is now Glycine rather than Serine.
<pre>New 513345 CAAGTTTCTATATGGGCTGCAAGAAAGGTGACAAAACACCGGAGGAAAAGTTTTTTGTGG 513404
|||||||||||||||||||||||||| |||||||||||||||||||||||||||||||||
Old 513339 CAAGTTTCTATATGGGCTGCAAGAAAAGTGACAAAACACCGGAGGAAAAGTTTTTTGTGG 513398</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR121C YBR121C]
| 481671
| 481675
| Substitution
| TGATG
| GTAGT
|-
| || colspan="6" | Nucleotide substitutions within the coding region of GRS1/YBR121C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 563-564 are now TT rather than HH.
<pre>New 481665 TTGGCGACTTCAGTAGTAACAGGAACTAAATCTTTGTGGTTAGATAAAGGAACTAAAAGA 481724
|||||||||||| | |||||||||||||||||||||||||||||||||||||||||||
Old 481659 TTGGCGACTTCATGATGAACAGGAACTAAATCTTTGTGGTTAGATAAAGGAACTAAAAGA 481718</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR108W YBR108W]
| 456359
| 456359
| Substitution
| C
| T
|-
| || colspan="6" | A single nucleotide substitution within the coding region of AIM3/YBR108W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 515 is now Valine rather than Alanine.
<pre>New 456345 AGGACATTATGATGTAGATGTCAACATCATGCCACCTCCAAAACCTTTCAGACATGGACT 456404
|||||||||||||||||||| |||||||||||||||||||||||||||||||||||||||
Old 456339 AGGACATTATGATGTAGATGCCAACATCATGCCACCTCCAAAACCTTTCAGACATGGACT 456398</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR295W YBR295W]
| 793986
| 793987
| Substitution
| AC
| CA
|-
| || colspan="6" | Nucleotide substitutions within the coding region of PCA1/YBR295W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 382 is now Histidine rather than Threonine.
<pre>New 793961 GGATTGTGCTGTTACCTCAACTATTTCTGGACACTCTTCGAGTGAAATTTCAAGAATCGT 794020
||||||||||||||||||||||||||||||| |||||||||||||||||||||||||||
Old 793955 GGATTGTGCTGTTACCTCAACTATTTCTGGAACCTCTTCGAGTGAAATTTCAAGAATCGT 794014</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR289W YBR289W]
| 781354
| 781354
| Substitution
| G
| C
|- style="height:30px; width:30px; text-align:center;"
| 780541
| 780541
| Substitution
| C
| A
|-
| || colspan="6" | Two nucleotide substitutions within the coding region of SNF5/YBR289W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 564 is now Aspartic Acid rather than Glutamic Acid.
<pre>New 780521 ACAACCTCCCACCAATGTTCAGCCAACTATTGGCCAACTTCCTCAACTTCCAAAATTAAA 780580
|||||||||||||||||||||||| |||||||||||||||||||||||||||||||||||
Old 780517 ACAACCTCCCACCAATGTTCAGCCCACTATTGGCCAACTTCCTCAACTTCCAAAATTAAA 780576
New 781311 GATATTGTCGTGGGACAAAACCAGTTAATCGATCAATTTGAGTGGGACATCTCTAATAGT 781370
||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
Old 781307 GATATTGTCGTGGGACAAAACCAGTTAATCGATCAATTTGAGTGGGAGATCTCTAATAGT 781366</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR288C YBR288C]
| 779354
| 779356
| Substitution
| TAC
| ACT
|-
| || colspan="6" | Nucleotide substitutions within the coding region of APM3/YBR288C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 35-36 are now QS rather than RT.
<pre>New 779321 TCACTACTGCTATCTTCGAGCAATTGAGGACATGTGGACTGAACGCGGGTCCACAGGTGC 779380
||||||||||||||||||||||||||||||||||||| ||||||||||||||||||||
Old 779317 TCACTACTGCTATCTTCGAGCAATTGAGGACATGTGGTACGAACGCGGGTCCACAGGTGC 779376</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBL099W YBL099W]
| 38210
| 38210
| Substitution
| A
| T
|- style="height:30px; width:30px; text-align:center;"
| 38067
| 38067
| Substitution
| C
| T
|-
| || colspan="6" | The substitution of 2 nucleotides within the coding region of ATP1/YBL099W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 340 is now Serine rather than Proline.
<pre>New 38039 AGCCTACCCTGGTGATGTCTTTTACTTGCATTCAAGATTGCTAGAAAGAGCCGCTAAGCT 38098
||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||||
Old 38036 AGCCTACCCTGGTGATGTCTTTTACTTGCATCCAAGATTGCTAGAAAGAGCCGCTAAGCT 38095
New 38169 GCTTATATTCCAACCAATGTTATTTCCATTACCGATGGTCAAATTTTCTTGGAAGCTGAA 38228
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 38166 GCTTATATTCCAACCAATGTTATTTCCATTACCGATGGTCAAATATTCTTGGAAGCTGAA 38225</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL097W YBL097W]
| 42377
| 42377
| Substitution
| C
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of BRN1/YBL097W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 517 is now Glycine rather than Alanine.
<pre>New 42359 CAAGATTGTTCATTAAACCGGGGCAGAAAATGAGTCTGTTCAGTCATAGGAAGCATACCA 42418
||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||
Old 42356 CAAGATTGTTCATTAAACCGGCGCAGAAAATGAGTCTGTTCAGTCATAGGAAGCATACCA 42415</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL091C YBL091C]
| 48369
| 48369
| Substitution
| A
| T
|-
| || colspan="6" | A single nucleotide substitution within the coding region of MAP2/YBL091C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 86 is now Aspartic Acid rather than Valine.
<pre>New 48359 ACGTGATTCTTCATCCGTGGTTCTTTGCAGATTGAAATCTTGATGATAGTCCATCCACGC 48418
||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||
Old 48356 ACGTGATTCTTCAACCGTGGTTCTTTGCAGATTGAAATCTTGATGATAGTCCATCCACGC 48415</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL088C YBL088C]
| 55145
| 55145
| Substitution
| A
| C
|-
| || colspan="6" | A single nucleotide substitution within the coding region of TEL1/YBL088C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 1412 is now Cysteine rather than Phenylalanine.
<pre>New 55139 GCATCAAGGCAGTATTTCCAAGTTTTTATTTTGATGAGATCCCGATGCTCTAAAAGCTTT 55198
||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||||
Old 55136 GCATCAAGGAAGTATTTCCAAGTTTTTATTTTGATGAGATCCCGATGCTCTAAAAGCTTT 55195</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL084C YBL084C]
| 68154
| 68155
| Substitution
| TG
| GA
|-
| || colspan="6" | The substitution of two nucleotides within the coding region of CDC27/YBL084C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 430 is now Serine rather than Glutamine.
<pre>New 68108 CGACCTTAATATTAAAGCGAAATTATACATGATTTCAGGCAGCGTAATTGAATAATCACT 68167
||||||||||||||||||||||||||||||||||||||||||||||||| |||||||||
Old 68105 CGACCTTAATATTAAAGCGAAATTATACATGATTTCAGGCAGCGTAATTTGATAATCACT 68164</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR275C YBR275C]
| 754908
| 754908
| Substitution
| T
| C
|-
| || colspan="6" | A single nucleotide substitution within the coding region of RIF1/YBR275C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 732 is now Alanine rather than Threonine.
<pre>New 754902 TACTTCAACAGCCTGGAACACAACTTTCATGATTTTATCGTATTCACGCTTGATGATCTG 754961
||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||
Old 754897 TACTTCAACAGTCTGGAACACAACTTTCATGATTTTATCGTATTCACGCTTGATGATCTG 754956</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR270C YBR270C]
| 743936
| 743938
| Substitution
| GCC
| CCG
|-
| || colspan="6" | Nucleotide substitutions within the coding region of BIT2/YBR270C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 152-153 are now SG rather than RA.
<pre>New 743922 AGTGCCGTAGTTTTTTGACCCGCTCCTGCTTCGATTTCTCATATTATCTTTTGAATTGGT 743981
||||||||||||||||||| | ||||||||||||||||||||||||||||||||||||||
Old 743917 AGTGCCGTAGTTTTTTGACGCCCTCCTGCTTCGATTTCTCATATTATCTTTTGAATTGGT 743976</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR266C YBR266C], [https://www.yeastgenome.org/locus/YBR267W YBR267W]
| 740291
| 740292
| Substitution
| CG
| GC
|-
| || colspan="6" | Nucleotide substitutions within the coding regions of overlapping genes REI1/YBR267W and SLM6/YBR266C resulted in altered sequences for both proteins. The start, stop, and reading frames of both proteins remain the same, but protein residues 152-153 of REI1/YBR267W are now KL rather than NV, and protein residue 31 of SLM6/YBR266C is now Serine rather than Threonine.
<pre>New 740262 AGGAAGAAATGGCGGAAAGAGTAATGCAAGAAAAGCTACGCAACAGAGTCGATATTCCAC 740321
|||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||
Old 740257 AGGAAGAAATGGCGGAAAGAGTAATGCAAGAAAACGTACGCAACAGAGTCGATATTCCAC 740316</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR265W YBR265W]
| 739341
| 739341
| Substitution
| A
| T
|-
| || colspan="6" | A single nucleotide substitution within the coding region of TSC10/YBR265W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 255 is now Aspartic Acid rather than Glutamic Acid.
<pre>New 739302 CAAGCATGTGATATCATTGCCAAGTCGCTGGCCAGAGGTGATGATGACGTTTTTACAGAT 739361
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 739297 CAAGCATGTGATATCATTGCCAAGTCGCTGGCCAGAGGTGATGAAGACGTTTTTACAGAT 739356</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR094W YBR094W]
| 433377
| 433378
| Substitution
| CG
| GC
|- style="height:30px; width:30px; text-align:center;"
| 432380
| 432380
| Substitution
| T
| C
|-
| || colspan="6" | Nucleotide changes within the coding region of PBY1/YBR094W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 450 is now Alanine rather than Arginine.
<pre>New 432345 GAGTGGATATTAATCGATGGAACTCCAGCATCGTGCGCAAACATCGGGCTGCACCTATTG 432404
||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||||
Old 432339 GAGTGGATATTAATCGATGGAACTCCAGCATCGTGCGCAAATATCGGGCTGCACCTATTG 432398
New 433365 ACTATTGATTTAGATTATGCTGAATTTCTAGACGACGCATTAGATGAAAATTGGGAATTA 433424
|||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||
Old 433359 ACTATTGATTTAGATTATCGTGAATTTCTAGACGACGCATTAGATGAAAATTGGGAATTA 433418</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR089C-A YBR089C-A]
| 426394
| 426396
| Substitution
| CCG
| GCC
|-
| || colspan="6" | Nucleotide substitutions within the coding region of NHP6B/YBR089C-A resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 30 is now Glycine rather than Arginine.
<pre>New 426355 GACAATGTCTCTGTTTTCATTAGCAAAGAACATATAAGCTGACAAGCCCCTCTTAGGGGC 426414
||||||||||||||||||||||||||||||||||||||||||||| | ||||||||||||
Old 426349 GACAATGTCTCTGTTTTCATTAGCAAAGAACATATAAGCTGACAACCGCCTCTTAGGGGC 426408</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBL056W YBL056W]
| 114870
| 114870
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 114868
| 114868
| Substitution
| G
| A
|-
| || colspan="6" | Two nucleotide substitutions within the coding region of PTC3/YBL056W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 369 is now Glycine rather than Aspartic Acid.
<pre>New 114832 CGACATGGAAATTGATGATCTTGATACCGAATTAGGCAGCAGTGCTACTCCCTCAAAGTT 114891
||||||||||||||||||||||||||||||||| | ||||||||||||||||||||||||
Old 114835 CGACATGGAAATTGATGATCTTGATACCGAATTGGACAGCAGTGCTACTCCCTCAAAGTT 114894</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="10"| 2011-02-03
| rowspan="10"| [https://www.yeastgenome.org/locus/YBR207W YBR207W]
| 636336
| 636336
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 636319
| 636322
| Substitution
| GCTT
| ACTG
|- style="height:30px; width:30px; text-align:center;"
| 636306
| 636309
| Substitution
| AATA
| TATG
|- style="height:30px; width:30px; text-align:center;"
| 636141
| 636141
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 635890
| 635890
| Deletion
| A
|
|- style="height:30px; width:30px; text-align:center;"
| 635882
| 635882
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 635247
| 635247
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 635192
| 635192
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 636342
| 636342
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 635822
| 635822
| Substitution
| C
| G
|-
| || colspan="6" | Nucleotide changes within the coding region of FTH1/YBR207W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 18 is now Glu rather than Lys, residue 36 is now Gly rather than Asp, residue 228 is now Glu rather than Gln, residues 249-250 are now VF rather than YS, residue 334 is now Gly rather than Glu, residues 389-390 are now IC rather than KY, and residues 399-401 are now EKY rather than GKC.
<pre>New 635196 GGAATCCTTAGAAATTGTTGTCATTGTTTCTATCCTGTTGACGATCGTCAAACAAGGTCT 635255
| |||||||||||||||||||||||||||||||||||||||||||||||||||||| |||
Old 635191 GAAATCCTTAGAAATTGTTGTCATTGTTTCTATCCTGTTGACGATCGTCAAACAAGATCT 635250
New 635803 ACCCAAAAAGGTGTGAAATTCAGTGAAAAGTACTCCTTCTTCATATTACCATTTATAACG 635862
|||||||||||||||||||||||| |||||||||||||||||||||||||||||||||||
Old 635798 ACCCAAAAAGGTGTGAAATTCAGTCAAAAGTACTCCTTCTTCATATTACCATTTATAACG 635857
New 635863 ACTTTGAGAGAAGGGTTAGAAGCTGTTGTATTC-ATTGGAGGTATCGGTATTGACCAACC 635921
||||||||||||||||||||||||| ||||||| ||||||||||||||||||||||||||
Old 635858 ACTTTGAGAGAAGGGTTAGAAGCTG-TGTATTCAATTGGAGGTATCGGTATTGACCAACC 635916
New 636102 AGACTACGTCAACAAATGTAACGGTCAAGACATGAGTGAAGTAGGAAATGGACCCGGTTC 636161
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 636097 AGACTACGTCAACAAATGTAACGGTCAAGACATGAGTGAAGTAGAAAATGGACCCGGTTC 636156
New 636292 GCCTACTGGTTGGTATTAATATGCGCTTTGAAACTGCTAATGATAGAAGAAAAATACGGA 636351
||||||||||||||||||| || ||||||||| || ||||||||||||| ||||| ||||
Old 636287 GCCTACTGGTTGGTATTAAAATACGCTTTGAAGCTTCTAATGATAGAAGGAAAATGCGGA 636346</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL014C YBL014C]
| 201635
| 201635
| Substitution
| G
| C
|-
| || colspan="6" | A single nucleotide substitution within the coding region of RRN6/YBL014C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 39 is now Lysine rather than Asparagine.
<pre>New 201592 CCTCGGCCAATGTATCATCTACTGGTCTTAGCCATTGTGGCTTTTCTTGCTTCTTCGTAG 201651
|||||||||||||||||||||||||||||||||||||||| |||||||||||||||||||
Old 201595 CCTCGGCCAATGTATCATCTACTGGTCTTAGCCATTGTGGGTTTTCTTGCTTCTTCGTAG 201654</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL008W YBL008W]
| 210433
| 210433
| Substitution
| A
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of HIR1/YBL008W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 260 is now Valine rather than Methionine.
<pre>New 210412 AATGGGCCCGTAAGTTCTGTGGCAATTGTAAATAGAGGAACTTGGGATACAAATGTTAGT 210471
|||||||||||||||||| |||||||||||||||||||||||||||||||||||||||||
Old 210415 AATGGGCCCGTAAGTTCTATGGCAATTGTAAATAGAGGAACTTGGGATACAAATGTTAGT 210474</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR043C YBR043C]
| 323835
| 323836
| Substitution
| CG
| GC
|-
| || colspan="6" | Nucleotide substitutions within the coding region of QDR3/YBR043C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 37 is now Serine rather than Threonine.
<pre>Query 323809 CTATAATCGTTGTGCTCGCTGTGCGGGCTGCCGCTGCTTTCATCGCAGTGCATCATAACA 323868
|||||||||||||||||||||||||| ||||||||||||||||||||||||||||||||
Sbjct 323809 CTATAATCGTTGTGCTCGCTGTGCGGCGTGCCGCTGCTTTCATCGCAGTGCATCATAACA 323868</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR141C YBR141C]
| 527099
| 527099
| Substitution
| A
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of YBR141C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 312 is now Proline rather than Serine.
<pre>New 527085 AAAGCTACTCGGCTGCGGTGGAACTACCTGCAATTGATACAAACAATAGTACAACTTATT 527144
|||||||||||||||||||| |||||||||||||||||||||||||||||||||||||||
Old 527079 AAAGCTACTCGGCTGCGGTGAAACTACCTGCAATTGATACAAACAATAGTACAACTTATT 527138</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR138C YBR138C]
| 514965
| 514966
| Substitution
| AC
| CA
|-
| || colspan="6" | Nucleotide substitutions within the coding region of YBR138C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 122 is now Leucine rather than Cysteine.
<pre>New 514955 TAGGCTTGGCACCTATCAATTGTGAGCGACGCTTTCTTACATTCAATAACTGTTGGTTCT 515014
|||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 514949 TAGGCTTGGCACCTATACATTGTGAGCGACGCTTTCTTACATTCAATAACTGTTGGTTCT 515008</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR004C YBR004C]
| 245111
| 245111
| Substitution
| T
| A
|-
| || colspan="6" | A single nucleotide substitution within the coding region of GPI18/YBR004C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 187 is now Serine rather than Threonine.
<pre>New 245092 TACGGGCACGGAAATGGAGCATTCACGACTCCAAATACCAACAAATGCAAAAAAAAAAGA 245151
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 245094 TACGGGCACGGAAATGGTGCATTCACGACTCCAAATACCAACAAATGCAAAAAAAAAAGA 245153</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="8"| 2011-02-03
| rowspan="8"| [https://www.yeastgenome.org/locus/YBL106C YBL106C]
| 13553
| 13553
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 13492
| 13492
| Substitution
| A
| T
|- style="height:30px; width:30px; text-align:center;"
| 13477
| 13477
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 13102
| 13102
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 11379
| 11379
| Substitution
| A
| C
|- style="height:30px; width:30px; text-align:center;"
| 11345
| 11345
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 11308
| 11309
| Substitution
| AA
| TT
|- style="height:30px; width:30px; text-align:center;"
| 11053
| 11053
| Substitution
| T
| C
|-
| || colspan="6" | Several nucleotide substitutions within the coding region of SRO77/YBL106C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 130 is now Isoleucine rather than Phenylalanine, residue 135 is now Serine rather than Proline, residue 260 is now Serine rather than Alanine, residue 834 is now Glycine rather than Valine, residue 858 is now Threonine rather than Serine, and 943 is now Glutamic Acid rather than Lysine.
<pre>New 11041 ACCTGTGATCTTCCGTACCGGGAGGTAACTTTCTGGCTGCATTACTACTACTGGAAGATA 11100
|||||||||||| |||||||||||||||||||||||||||||||||||||||||||||||
Old 11041 ACCTGTGATCTTTCGTACCGGGAGGTAACTTTCTGGCTGCATTACTACTACTGGAAGATA 11100
New 11281 GTTGTGATATGTCAGCAGTATGATTCGTTCCGGTGGCACTTTCATTAAGTACTGAAATCA 11340
||||||||||||||||||||||||||| |||||||||||||||||||||||||||||||
Old 11281 GTTGTGATATGTCAGCAGTATGATTCGAACCGGTGGCACTTTCATTAAGTACTGAAATCA 11340
New 11341 AAGAGGCTTGGAATTTCCCTGTGCGAATGACAATGTCACCATTTTCTAATATAGATGAAT 11400
|||| ||||||||||||||||||||||||||||||||| |||||||||||||||||||||
Old 11341 AAGAAGCTTGGAATTTCCCTGTGCGAATGACAATGTCAACATTTTCTAATATAGATGAAT 11400
New 13081 TGACATCCCAAAATACCAAGGAATTATCTTCATGGACAGTTAATATATGTAAGGAATTTG 13140
||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||
Old 13081 TGACATCCCAAAATACCAAGGCATTATCTTCATGGACAGTTAATATATGTAAGGAATTTG 13140
New 13441 ATCCACTCTCGAGGCCAATCAGCATCCAATCCAAGGACGGATCAGTCTCAATACAAGTGA 13500
|||||||||||||||||||||||||||||||||||| |||||||||||||| ||||||||
Old 13441 ATCCACTCTCGAGGCCAATCAGCATCCAATCCAAGGGCGGATCAGTCTCAAAACAAGTGA 13500
New 13501 TGCTGTTTGGACAGAAAACAGTAGTTAGAATCTGTTTCGAGTGTACTGAAAGAACTATTA 13560
|||||||||||||||||||||||||||||||||||||||||||||||||||| |||||||
Old 13501 TGCTGTTTGGACAGAAAACAGTAGTTAGAATCTGTTTCGAGTGTACTGAAAGGACTATTA 13560</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="6"| 2011-02-03
| rowspan="6"| [https://www.yeastgenome.org/locus/YBR203W YBR203W]
| 631936
| 631936
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 631924
| 631924
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 631912
| 631912
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 631907
| 631907
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 631342
| 631353
| Substitution
| GCTGGCGAAACG
| CGTTTCGCCAGC
|- style="height:30px; width:30px; text-align:center;"
| 631940
| 631940
| Substitution
| C
| A
|-
| || colspan="6" | Nucleotide changes within the coding region of COS111/YBR203W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 727-731 are now TFRQH rather than SWRND, residue 917 is now Asparagine rather than Serine, and residue 921 is now Glutamic Acid rather than Glycine.
<pre>New 631303 TGTGTGGTGCAGGCAATATATGGTAAAGTATTTTGTAATGAGGACGTTTCGCCAGCATTT 631362
|||||||||||||||||||||||||||||||||||||||||||| | || | ||||
Old 631298 TGTGTGGTGCAGGCAATATATGGTAAAGTATTTTGTAATGAGGAGCTGGCGAAACGATTT 631357
New 631903 TGTTGGCGAAAATAACTACTATGCTGAAAGCATCATATAACGACTGCTCTCTTTTAACAG 631962
||||||||| |||| ||||||||||| ||||||||||| ||| |||||||||||||||||
Old 631898 TGTTGGCGAGAATAGCTACTATGCTGGAAGCATCATATGACGCCTGCTCTCTTTTAACAG 631957</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR285W YBR285W]
| 774080
| 774080
| Substitution
| C
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of YBR285W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 55 is now Aspartic Acid rather than Histidine.
<pre>New 774041 CTTAGAAAGCCCCACTGACGATAGCATGGAGGCGGACATTTCAGATAGAGAAATGGCTAC 774100
||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||
Old 774037 CTTAGAAAGCCCCACTGACGATAGCATGGAGGCGGACATTTCACATAGAGAAATGGCTAC 774096</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR204C YBR204C]
| 633189
| 633189
| Substitution
| T
| A
|-
| || colspan="6" | A single nucleotide substitution within the coding region of YBR204C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 63 is now Valine rather than Glutamic Acid.
<pre>New 633163 CCTTATTCTTGAATTTCGATCCGATAGTTGTACATTAAAAAACTCCTCATGTTCTGCGAT 633222
||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||||
Old 633158 CCTTATTCTTGAATTTCGATCCGATAGTTGTTCATTAAAAAACTCCTCATGTTCTGCGAT 633217</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBR202W YBR202W]
| 627486
| 627487
| Substitution
| AT
| TA
|- style="height:30px; width:30px; text-align:center;"
| 627433
| 627439
| Substitution
| ATCCGGG
| CTTTGAA
|- style="height:30px; width:30px; text-align:center;"
| 627421
| 627421
| Substitution
| T
| G
|-
| || colspan="6" | Nucleotide changes within the coding region of MCM7/YBR202W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 552-558 is now GINTTLN rather than VINTNPG, and residue 574 is now Tyrosine rather than Isoleucine.
<pre>New 627403 AACAATTTCGATATCCAAGGCGGGTATCAATACAACTTTGAACGCCAGAACCTCAATCTT 627462
||||||||||||||||||||||| ||||||||||| | | ||||||||||||||||||
Old 627398 AACAATTTCGATATCCAAGGCGGTTATCAATACAAATCCGGGCGCCAGAACCTCAATCTT 627457
New 627463 AGCGGCAGCAAATCCGTTGTATGGTAGATATAATCCTAGATTATCACCTCTGGACAATAT 627522
|||||||||||||||||||||||||||| ||||||||||||||||||||||||||||||
Old 627458 AGCGGCAGCAAATCCGTTGTATGGTAGAATTAATCCTAGATTATCACCTCTGGACAATAT 627517</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL080C YBL080C]
| 73450
| 73450
| Substitution
| C
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of PET112/YBL080C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 415 is now Proline rather than Alanine.
<pre>New 73438 CGAAAACCGGAGGAGGCAAAATTTCTTTTGCTTTGGCCAATGGAATTTGTAGCTTGTTCA 73497
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Old 73435 CGAAAACCGGAGGAGCCAAAATTTCTTTTGCTTTGGCCAATGGAATTTGTAGCTTGTTCA 73494</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL067C YBL067C]
| 95345
| 95345
| Substitution
| G
| T
|-
| || colspan="6" | A single nucleotide substitution within the coding region of UBP13/YBL067C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 180 is now Glutamine rather than Histidine.
<pre>New 95333 TCTTTCTTGGTTGATCAGATTCTCTTGATTTTTTTGGAAATTGCAATATATTTTCACGTA 95392
|||||||||| |||||||||||||||||||||||||||||||||||||||||||||||||
Old 95335 TCTTTCTTGGGTGATCAGATTCTCTTGATTTTTTTGGAAATTGCAATATATTTTCACGTA 95394</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR074W YBR074W]
| 388774
| 388775
| Substitution
| TT
| AA
|-
| || colspan="6" | Nucleotide substitutions within the coding region of YBR074W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 832 is now Asparagine rather than Phenylalanine.
<pre>New 388738 ACGAACCAATAGTTGCAGAGTTACTTTTGGAGGTGAAGGAGAACAGGGCTTGCACTTTAA 388797
||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 388733 ACGAACCAATAGTTGCAGAGTTACTTTTGGAGGTGAAGGAGTTCAGGGCTTGCACTTTAA 388792</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR073W YBR073W]
| 385360
| 385361
| Substitution
| CG
| GC
|-
| || colspan="6" | Nucleotide substitutions within the coding region of RDH54/YBR073W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 752 is now Alanine rather than Arginine.
<pre>New 385318 TCTTGTTGAGTGCAAAATCGGGAGGTGTAGGATTGAATCTAGTCGGTGCTTCGCGACTTA 385377
||||||||||||||||||||||||||||||||||||||||||||||| |||||||||||
Old 385313 TCTTGTTGAGTGCAAAATCGGGAGGTGTAGGATTGAATCTAGTCGGTCGTTCGCGACTTA 385367</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR152W YBR152W], [https://www.yeastgenome.org/locus/YBR153W YBR153W]
| 547442
| 547442
| Substitution
| A
| T
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs SPP381/YBR152W and RIB7/YBR153W.
<pre>New 547425 GCTTCTTTGTATTACTATCAACATTTTTAGAAGATATGTCTTTGACACCACTGTGTGAAG 547484
||||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||
Old 547419 GCTTCTTTGTATTACTATCAACAATTTTAGAAGATATGTCTTTGACACCACTGTGTGAAG 547478</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBLCtau1 YBLCtau1], [https://www.yeastgenome.org/locus/tF(GAA)B tF(GAA)B]
| 36312
| 36312
| Substitution
| T
| A
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between Ty4 LTR YBLCtau1 and tRNA-Phe tF(GAA)B.
<pre>New 36299 TGTGCTTCAGTATTACATTTTTTGCCTTCAACGCCTTGATTGTTCTATTTTTGCTAATAA 36358
|||||||||||||||| |||||||||||||||||||||||||||||||||||||||||||
Old 36296 TGTGCTTCAGTATTACTTTTTTTGCCTTCAACGCCTTGATTGTTCTATTTTTGCTAATAA 36355</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL099W YBL099W], [https://www.yeastgenome.org/locus/tF(GAA)B tF(GAA)B]
| 36673
| 36673
| Substitution
| A
| T
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between tRNA-Phe tF(GAA)B and ORF ATP1/YBL099W.
<pre>New 36659 ATTTATTGTAATTATTATACATTGGTCATATCAAATTCACATCAGACTTCAATTTTTCAA 36718
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 36656 ATTTATTGTAATTATTAAACATTGGTCATATCAAATTCACATCAGACTTCAATTTTTCAA 36715</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR006W YBR006W], [https://www.yeastgenome.org/locus/YBR007C YBR007C]
| 248623
| 248623
| Insertion
|
| T
|-
| || colspan="6" | A single nucleotide insertion was made in the intergenic region between ORFs UGA2/YBR006W and DSF2/YBR007C.
<pre>New 248572 GCATGTATAAATACTCTACTCCTCGTATATAGAAAGTTAAGTAAATTTTTTGAAAGAAAA 248631
|||||||||||||||||||||||||||||||||||||||||||||||||| |||||||||
Old 248574 GCATGTATAAATACTCTACTCCTCGTATATAGAAAGTTAAGTAAATTTTT-GAAAGAAAA 248632</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR001C YBR001C], [https://www.yeastgenome.org/locus/YBR002C YBR002C]
| 241396
| 241396
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 241359
| 241359
| Substitution
| G
| A
|-
| || colspan="6" | Two separate single nucleotide substitutions were made in the intergenic region between ORFs NTH2/YBR001C and RER2/YBR002C.
<pre>New 241352 AAAGGAAAAATATAAATAAATAAATAAAATTGAGAAATAAAGATATTTAGTTTTAATGGA 241411
||||| |||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 241354 AAAGGGAAAATATAAATAAATAAATAAAATTGAGAAATAAAGGATATTAGTTTTAATGGA 241413</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL005W YBL005W], [https://www.yeastgenome.org/locus/YBLWdelta8 YBLWdelta8]
| 220413
| 220414
| Substitution
| AG
| GA
|-
| || colspan="6" | A dinucleotide substitution was made in the intergenic region between ORF PDR3/YBL005W and Ty1 LTR YBLWdelta8.
<pre>New 220372 ATGACAATACTTCATATCCCTTCTTATGAAAACGCAAAGAAAATAGGGAAGCAGAGCATA 220431
|||||||||||||||||||||||||||||||||||||| ||||||||||||||||||||
Old 220375 ATGACAATACTTCATATCCCTTCTTATGAAAACGCAAAAGAAATAGGGAAGCAGAGCATA 220434</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBL105C YBL105C], [https://www.yeastgenome.org/locus/YBL106C YBL106C]
| 13982
| 13982
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 13966
| 13966
| Substitution
| C
| A
|-
| || colspan="6" | Two separate single nucleotide substitutions were made in the intergenic region between ORFs SRO77/YBL106C and PKC1/YBL105C.
<pre>New 13941 AGAAATATGTTAGTAGTAATATAATACTGAGCTGTTTCTTAAATGCTTCCTTAATAATGT 14000
||||||||||||||||||||||||| ||||||||||||||| ||||||||||||||||||
Old 13941 AGAAATATGTTAGTAGTAATATAATCCTGAGCTGTTTCTTAGATGCTTCCTTAATAATGT 14000</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="6"| 2011-02-03
| rowspan="6"| [https://www.yeastgenome.org/locus/ARS209 ARS209]
| 254720
| 254720
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 254719
| 254719
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 254616
| 254616
| Substitution
| T
| A
|- style="height:30px; width:30px; text-align:center;"
| 254548
| 254548
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 254532
| 254532
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 254495
| 254495
| Substitution
| G
| T
|-
| || colspan="6" | Several nucleotide changes were made within ARS209.
<pre>New 254452 AAATATCCTTTTTTTTTTCTTTGCATTTGTCTTCTTTCATTTTAAATCTTCATAATCTTC 254511
|||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 254453 AAATATCCTTTTTTTTTTCTTTGCATTTGTCTTCTTTCATTTGAAATCTTCATAATCTTC 254512
New 254512 CGGAAAAACTAGTGATGCGAAATATTGTAGAGAAAAAGCGCAGGGCATTCCTATACTTAG 254571
||||||||||||||||||| |||||||||||||||| |||||||||||||||||||||||
Old 254513 CGGAAAAACTAGTGATGCGCAATATTGTAGAGAAAA-GCGCAGGGCATTCCTATACTTAG 254571
New 254572 TAATCACCATCATAACGTATTTTAAAATGAAGAAGCGAACCTCAAAGAATTTTCTATACA 254631
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 254572 TAATCACCATCATAACGTATTTTAAAATGAAGAAGCGAACCTCATAGAATTTTCTATACA 254631
New 254692 TATATTGCAGAAAATGTGCTAGTAATATTGTTCTCTCTGTTGTCAATGGGCTTACAATTG 254751
|||||||||||||||||||||||||||| | |||||||||||||||||||||||||||||
Old 254692 TATATTGCAGAAAATGTGCTAGTAATAT-G-TCTCTCTGTTGTCAATGGGCTTACAATTG 254749</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR285W YBR285W], [https://www.yeastgenome.org/locus/YBR286W YBR286W]
| 774430
| 774430
| Substitution
| C
| G
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs YBR285W and APE3/YBR286W.
<pre>New 774401 CTTATCGTCAGAAAGAGTGTTCTCTATGTTTTTGTGCTTCCATAAATATATAGTTCAAAA 774460
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||
Old 774397 CTTATCGTCAGAAAGAGTGTTCTCTATGTTTTTCTGCTTCCATAAATATATAGTTCAAAA 774456</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/ARS221 ARS221]
| 631981
| 631981
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 631940
| 631940
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 631936
| 631936
| Substitution
| G
| A
|-
| || colspan="6" | Three single nucleotide substitutions were made within ARS221.
<pre>New 631933 CATCATATAACGACTGCTCTCTTTTAACAGCATACGTTCTGTTAATTTATTTGGCCAAAT 631992
|||||||| ||| |||||||||||||||||||||||||||||||||||||||| ||||||
Old 631928 CATCATATGACGCCTGCTCTCTTTTAACAGCATACGTTCTGTTAATTTATTTGACCAAAT 631987</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/ARS213 ARS213]
| 390033
| 390033
| Insertion
|
| C
|-
| || colspan="6" | A single nucleotide insertion was made within ARS213.
<pre>New 389998 ACTGACACTAAAAAAAGGGTCGTACGTCTTACTGGCAGCGCCGAAAAATGTTTCGAAAAT 390057
||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||||
Old 389993 ACTGACACTAAAAAAAGGGTCGTACGTCTTACTGGCAGCGC-GAAAAATGTTTCGAAAAT 390051</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR201C-A YBR201C-A], [https://www.yeastgenome.org/locus/YBR202W YBR202W]
| 625500
| 625500
| Substitution
| T
| C
|- style="height:30px; width:30px; text-align:center;"
| 625435
| 625435
| Insertion
|
| T
|-
| || colspan="6" | A single nucleotide insertion and a single nucleotide substitution were made in the intergenic region between ORFs YBR201C-A and MCM7/YBR202W.
<pre>New 625423 ATTTTCTCAATAACAGGTCGAGGCCCCTTCTACCCTTGAATGCTACTTATTACTCACTCA 625482
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 625419 ATTTTCTCAATAACAGG-CGAGGCCCCTTCTACCCTTGAATGCTACTTATTACTCACTCA 625477
New 625483 TAATACATTGTATAAGCCTTCGCGTTTTTCACGGCCTCGAAAAAATTTTTCTTAACTAAT 625542
|||||||||||||||||||||| |||||||||||||||||||||||||||||||||||||
Old 625478 TAATACATTGTATAAGCCTTCGTGTTTTTCACGGCCTCGAAAAAATTTTTCTTAACTAAT 625537</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR200W-A YBR200W-A], [https://www.yeastgenome.org/locus/YBR201W YBR201W]
| 623444
| 623444
| Deletion
| C
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORFs YBR200W-A and DER1/YBR201W.
<pre>New 623434 GAAGGTATAACAAAA-CAGATAGACACCTAATAAAGAACAAAATATTCCTATAGTTTTGC 623492
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Old 623429 GAAGGTATAACAAAACCAGATAGACACCTAATAAAGAACAAAATATTCCTATAGTTTTGC 623488</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL001C YBL001C], [https://www.yeastgenome.org/locus/YBL002W YBL002W]
| 237021
| 237021
| Insertion
|
| G
|-
| || colspan="6" | A single nucleotide insertion was made in the intergenic region between ORFs HTB2/YBL002W and ECM15/YBL001C.
<pre>New 236992 AGGGTCTAGTCTATCAGCCTCCGAAGGGAGTTGTATAAATGTATATATATAACTTTATAA 237051
||||||||||||||||||||||||||| ||||||||||||||||||||||||||||||||
Old 236995 AGGGTCTAGTCTATCAGCCTCCGAAGG-AGTTGTATAAATGTATATATATAACTTTATAA 237053</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/ARS208 ARS208], [https://www.yeastgenome.org/locus/CEN2 CEN2]
| 238133
| 238133
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 238116
| 238116
| Substitution
| G
| A
|-
| || colspan="6" | Two separate single nucleotide substitutions were made in the intergenic region between ARS208 and CEN2.
<pre>New 238082 AGTACTTGCTTTCAGCAGAAAATGAAAAAAAGAACGTTCAAACAGACTGAAAATATAGCT 238141
|||||||||||||||||||||||||||||||| |||||||||||||||| ||||||||||
Old 238084 AGTACTTGCTTTCAGCAGAAAATGAAAAAAAGGACGTTCAAACAGACTGGAAATATAGCT 238143</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL079W YBL079W], [https://www.yeastgenome.org/locus/YBL080C YBL080C]
| 75208
| 75208
| Substitution
| A
| G
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs PET112/YBL080C and NUP170/YBL079W.
<pre>New 75178 GGAGAATTACTGGAACCTAGGATCTGACAAGCGGACAAAAAAGCAGAGTGCGTTTATTAC 75237
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||
Old 75175 GGAGAATTACTGGAACCTAGGATCTGACAAGCGAACAAAAAAGCAGAGTGCGTTTATTAC 75234</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL077W YBL077W], [https://www.yeastgenome.org/locus/YBL078C YBL078C]
| 80747
| 80747
| Deletion
| T
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORFs ATG8/YBL078C and YBL077W.
<pre>New 80708 TTCAGACTTAAATGTAGACTTCATGTCTCTAGTAATTATTTT-ATTATGATTTTCTCAAC 80766
|||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 80705 TTCAGACTTAAATGTAGACTTCATGTCTCTAGTAATTATTTTTATTATGATTTTCTCAAC 80764</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL072C YBL072C]
| 89277
| 89277
| Substitution
| G
| T
|-
| || colspan="6" | A single nucleotide substitution was made within the 5' UTR intron of ORF RPS8A/YBL072C.
<pre>New 89267 GGCTTGATTTTTTGGGTACACAAAGGATTCAGTTTAGTGCACTGCTCCTGTCACAATTTA 89326
|||||||||||| |||||||||||||||||||||||||||||||||||||||||||||||
Old 89265 GGCTTGATTTTTGGGGTACACAAAGGATTCAGTTTAGTGCACTGCTCCTGTCACAATTTA 89324</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL067C YBL067C], [https://www.yeastgenome.org/locus/YBL068W YBL068W]
| 93622
| 93622
| Deletion
| C
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORFs PRS4/YBL068W and UBP13/YBL067C.
<pre>New 93594 AAAGGAGACGGTGAACCTTTACCTTCC-TTGATATGCAAATATTTTTCAGCTTTTCCTAA 93652
||||||||||||||||||||||||||| ||||||||||||||||||||||||||||||||
Old 93595 AAAGGAGACGGTGAACCTTTACCTTCCCTTGATATGCAAATATTTTTCAGCTTTTCCTAA 93654</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="4"| 2011-02-03
| rowspan="4"| [https://www.yeastgenome.org/locus/YBR077C YBR077C], [https://www.yeastgenome.org/locus/YBR078W YBR078W]
| 392822
| 392822
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 392568
| 392569
| Substitution
| CG
| GC
|- style="height:30px; width:30px; text-align:center;"
| 392557
| 392558
| Substitution
| CG
| GC
|- style="height:30px; width:30px; text-align:center;"
| 392340
| 392340
| Deletion
| TT
|
|-
| || colspan="6" | Several nucleotide changes were made in the intergenic region between ORFs SLM4/YBR077C and ECM33/YBR078W.
<pre>New 392327 GATAACTGCCTTTTTTTTTT--CTTCTTATCTTCCCTTAATTAATTCATTAGAGTCTTTT 392384
|||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||
Old 392321 GATAACTGCCTTTTTTTTTTTTCTTCTTATCTTCCCTTAATTAATTCATTAGAGTCTTTT 392380
New 392545 CACGACCCGGGTGGCTGCTGCGCCCTCGCGAAAAAGAAATGAAATGGAGTGCAAAAACGG 392604
|||||||||||||||| ||||||||| |||||||||||||||||||||||||||||||
Old 392541 CACGACCCGGGTGGCTCGTGCGCCCTCCGGAAAAAGAAATGAAATGGAGTGCAAAAACGG 392600
New 392805 AATGTCAAACACCTACGACTTTTCGCAATCAACGGACCTCTCTTGCATTTTTGTATTTAA 392864
|||||||||||||||||||||| |||||||||||||||||||||||||||||||||||||
Old 392801 AATGTCAAACACCTACGACTTT-CGCAATCAACGGACCTCTCTTGCATTTTTGTATTTAA 392859</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR072C-A YBR072C-A], [https://www.yeastgenome.org/locus/YBR072W YBR072W]
| 382742
| 382742
| Insertion
|
| G
|- style="height:30px; width:30px; text-align:center;"
| 382729
| 382729
| Insertion
|
| G
|-
| || colspan="6" | Two separate single nucleotide insertions were made in the intergenic region between ORFs HSP26/YBR072W and YBR072C-A.
<pre>New 382719 TTGCTTGCATATGGGCTTGAAACATATGGTCATCACATCTGAGCGATTTTACCTCTTAGA 382778
|||||||||||||| ||||||||||||| |||||||||||||||||||||||||||||||
Old 382716 TTGCTTGCATATGG-CTTGAAACATATG-TCATCACATCTGAGCGATTTTACCTCTTAGA 382773</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR066C YBR066C], [https://www.yeastgenome.org/locus/YBR067C YBR067C]
| 371424
| 371424
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 370774
| 370773
| Substitution
| C
| T
|-
| || colspan="6" | A single nucleotide substitution and a single nucleotide insertion were made in the intergenic region between ORFs NRG2/YBR066C and TIP1/YBR067C.
<pre>New 370729 TTGTTCTTCGAACAGTAGCGAGTGCTCATATGACTTGGTGCCGGAAATTCATTTGAGCTG 370788
||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
Old 370727 TTGTTCTTCGAACAGTAGCGAGTGCTCATATGACTTGGTGCCGGAAACTCATTTGAGCTG 370786
New 371389 AAGGTTATAGTCTCCTTTTTTTCTTGGCTTCGGGAAAAATACGATTTGTTTGTTATTCTA 371448
|||||||||||||||||||||||||||||||||||||| |||||||||||||||||||||
Old 371387 AAGGTTATAGTCTCCTTTTTTTCTTGGCTTCGGGAAAA-TACGATTTGTTTGTTATTCTA 371445</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/ARS230 ARS230], [https://www.yeastgenome.org/locus/YBL100W-C YBL100W-C]
| 28909
| 28909
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 28887
| 28887
| Insertion
|
| AT
|-
| || colspan="6" | A dinucleotide insertion and a mononucleotide insertion were made in the intergenic region between ORF YBL100W-C and ARS230.
<pre>New 28859 ATTACTGTTTCGGGAATATAACGTTTGATATCGCTAGCGCACCCAGATGAGAAATCCGCA 28918
||||||||||||||||||||||||||||| |||||||||||||||||||||| ||||||
Old 28859 ATTACTGTTTCGGGAATATAACGTTTGAT--CGCTAGCGCACCCAGATGAGAA-TCCGCA 28915</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/ARS228 ARS228]
| 792273
| 792273
| Insertion
|
| T
|-
| || colspan="6" | A single nucleotide insertion was made within ARS228.
<pre>New 792231 TTTGTTATGAATCTGAAAAGAAAAATACTATTTTAGCAATACAATGAATTTTAAAAAGTT 792290
|||||||||||||||||||||||||||||||||||||||||||||||| |||||||||||
Old 792226 TTTGTTATGAATCTGAAAAGAAAAATACTATTTTAGCAATACAATGAA-TTTAAAAAGTT 792284</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/ARS225 ARS225], [https://www.yeastgenome.org/locus/YBR275C YBR275C]
| 757291
| 757291
| Deletion
| A
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORF RIF1/YBR275C and ARS225.
<pre>New 757242 ATCTTCTTGCTAACGATGAGTCGCCAATAAATAAAAAATCGACG-CGTCGGTCAATTATA 757310
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 757237 ATCTTCTTGCTAACGATGAGTCGCCAATAAATAAAAAATCGACGACGTCGGTCAATTATA 757306</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/ARS208 ARS208]
| 237892
| 237892
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 237839
| 237839
| Substitution
| G
| A
|-
| || colspan="6" | Two separate single nucleotide substitutions were made within ARS208.
<pre>New 237832 TTGCGAAAATTATTCTTTAATAGTTTAACTAAAAGTAAAAAGTTAGAAATCATAAATAAA 237891
||||| |||||||||||||||||||||||||||||||||||||||||||||||||||| |
Old 237834 TTGCGGAAATTATTCTTTAATAGTTTAACTAAAAGTAAAAAGTTAGAAATCATAAATAGA 237893</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL103C YBL103C], [https://www.yeastgenome.org/locus/YBL104C YBL104C]
| 21376
| 21376
| Insertion
|
| A
|-
| || colspan="6" | A single nucleotide insertion was made in the intergenic region between ORFs YBL104C and RTG3/YBL103C.
<pre>New 21361 CTTATGCTATCTTGAAATATATCATCGCCGTAAAGTATGATGTGTAGCGCATTAGTCTTC 21420
|||||||||||||||| |||||||||||||||||||||||||||||||||||||||||||
Old 21361 CTTATGCTATCTTGAA-TATATCATCGCCGTAAAGTATGATGTGTAGCGCATTAGTCTTC 21419</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBL102W YBL102W], [https://www.yeastgenome.org/locus/YBL103C YBL103C]
| 28913
| 28913
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 23855
| 23856
| Deletion
| CC
|
|- style="height:30px; width:30px; text-align:center;"
| 23947
| 23947
| Insertion
|
| A
|-
| || colspan="6" | Several sequence changes were made in the intergenic region between ORFs RTG3/YBL103C and SFT2/YBL102W.
<pre>New 23821 GAAGGCTTTTCTAATCACCATGGCTTTATTATTTC--AAAAGTAACTTGCGAAGAGTCAC 23878
||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
Old 23820 GAAGGCTTTTCTAATCACCATGGCTTTATTATTTCCCAAAAGTAACTTGCGAAGAGTCAC 23879
New 23879 ATCCCGCGGAACGGCCCGCAATCGTGACCCGGCAAAAGGCGATTGTAATGAAGAGGGAGT 23938
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||
Old 23880 ATCCCGCGGAACGGCCCGCAATCGTGACCCGGCCAAAGGCGATTGTAATGAAGAGGGAGT 23939
New 23939 ATTGGTCAAGACTTGTACTATACTGAAATAGGAAGAAGATTGAATAAATTTGCATTCTAA 23998
|||||||| |||||||||||||||||||||||||||||||||||||||||||||||||||
Old 23940 ATTGGTCA-GACTTGTACTATACTGAAATAGGAAGAAGATTGAATAAATTTGCATTCTAA 23998</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR125C YBR125C], [https://www.yeastgenome.org/locus/YBR126C YBR126C]
| 488600
| 488601
| Substitution
| TC
| AT
|-
| || colspan="6" | A dinucleotide substitution was made in the intergenic region between ORFs PTC4/YBR125C and TPS1/YBR126C.
<pre>New 488565 CGTTATGCGGTGTGAACAGCGACAATAAAAAAAAATGTGGGATAAATTATGGCTTTTTTT 488624
||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 488559 CGTTATGCGGTGTGAACAGCGACAATAAAAAAAAATGTGGGTCAAATTATGGCTTTTTTT 488618</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR102C YBR102C], [https://www.yeastgenome.org/locus/YBR103W YBR103W]
| 447535
| 447536
| Substitution
| CG
| GC
|-
| || colspan="6" | A dinucleotide substitution was made in the intergenic region between ORFs EXO84/YBR102C and SIF2/YBR103W.
<pre>New 447525 AAAGGTTATGAGATATGCAAGACCATTCGTTTTGATTTGCAATTAGTGAGAACAATTTAA 447584
|||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 447519 AAAGGTTATGAGATATCGAAGACCATTCGTTTTGATTTGCAATTAGTGAGAACAATTTAA 447578</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBR013C YBR013C], [https://www.yeastgenome.org/locus/YBRCdelta14 YBRCdelta14]
| 265922
| 265922
| Deletion
| C
|
|- style="height:30px; width:30px; text-align:center;"
| 265905
| 265905
| Substitution
| T
| G
|- style="height:30px; width:30px; text-align:center;"
| 265902
| 265902
| Deletion
| C
|
|-
| || colspan="6" | Several nucleotide changes were made within the intergenic region between ORF YBR013C and Ty1 LTR YBRCdelta14.
<pre>New 265852 GATACATATCCTGAATAAGGGATATATCATTATGAGGTTAAGTGGCCTAAAA-ACGCAAT 265910
|||||||||||||||||||||||||||||||||||||||||||||||||||| || ||||
Old 265850 GATACATATCCTGAATAAGGGATATATCATTATGAGGTTAAGTGGCCTAAAACACTCAAT 265909
New 265911 TAATACGGATCC-TTGTACTATTAAGTCTTTTCTATCTCTGAAAATTAACTTAAGAAGCG 265969
|||||||||||| |||||||||||||||||||||||||||||||||||||||||||||||
Old 265910 TAATACGGATCCCTTGTACTATTAAGTCTTTTCTATCTCTGAAAATTAACTTAAGAAGCG 265969</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR295W YBR295W], [https://www.yeastgenome.org/locus/YBR296C YBR296C]
| 796707
| 796707
| Substitution
| A
| G
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs PCA1/YBR295W and PHO89/YBR296C.
<pre>New 796671 TAAATTAGAAAAAAATTAATGCATCTTTAAGGTTTTAAATTAGAAATGTTTTAACTTTAA 796730
|||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 796665 TAAATTAGAAAAAAATTAATGCATCTTTAAGGTTTTAAATTAAAAATGTTTTAACTTTAA 796724</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR292C YBR292C], [https://www.yeastgenome.org/locus/YBR293W YBR293W]
| 786761
| 786761
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 786736
| 786737
| Substitution
| CT
| TC
|-
| || colspan="6" | Several nucleotide changes were made in the intergenic region between ORFs YBR292C and YBR293W.
<pre>New 786721 TTCCAAATCAGATTTTTTTTCGCAATGCTTAAATCTAGTAAACACAAAGTACTACCGAAA 786780
||||||||||||||||||| |||||||||||||||||||||||| ||||||||||||||
Old 786717 TTCCAAATCAGATTTTTTTCTGCAATGCTTAAATCTAGTAAACAC-AAGTACTACCGAAA 786776
New 786761 AACACAAAGTACTACCGAAAAGCAAGGATGGAAACTATGGCAGTATTGAAGAGACTGAAA 786820
||||| ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Old 786757 AACAC-AAGTACTACCGAAAAGCAAGGATGGAAACTATGGCAGTATTGAAGAGACTGAAA 786815</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="4"| 2011-02-03
| rowspan="4"| [https://www.yeastgenome.org/locus/YBL098W YBL098W], [https://www.yeastgenome.org/locus/YBL099W YBL099W]
| 38920
| 38920
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 38917
| 38917
| Substitution
| C
| T
|- style="height:30px; width:30px; text-align:center;"
| 38800
| 38800
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 38728
| 38728
| Substitution
| C
| A
|-
| || colspan="6" | Several single nucleotide substitutions were made in the intergenic region between ORFs ATP1/YBL099W and BNA4/YBL098W.
<pre>New 38699 AAAAAAATAAAAATGAATATAAGGTACGTCTCAAAAAGAAATGTAAATATAGAAATTTTA 38758
|||||||||||||||||||||||||||||||| |||||||||||||||||||||||||||
Old 38696 AAAAAAATAAAAATGAATATAAGGTACGTCTCCAAAAGAAATGTAAATATAGAAATTTTA 38755
New 38759 AAAAAAAAAACGAAAAAAAACATAACTAAATTTAAAGTGCAGCCAAACAATAACCCTGAA 38818
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 38756 AAAAAAAAAACGAAAAAAAACATAACTAAATTTAAAGTGCAGCCCAACAATAACCCTGAA 38815
New 38879 GTAAATAATGCCCCTACTTTTCTTCTAAGGAAATGAGTTACTACAAAAATAAGGAAATAT 38938
|||||||||||||||||||||||||||||||| |||||||| || |||||||||||||||
Old 38876 GTAAATAATGCCCCTACTTTTCTTCTAAGGAAGTGAGTTACCACCAAAATAAGGAAATAT 38935</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL092W YBL092W], [https://www.yeastgenome.org/locus/YBL093C YBL093C]
| 45495
| 45495
| Substitution
| T
| A
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs ROX3/YBL093C and RPL32/YBL092W.
<pre>New 45479 ACTGGAGAAGAGTGTTTGAATCCAGCAGAAGGTAATACGCACCTTTCTCATCTATTTGCA 45538
||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||
Old 45476 ACTGGAGAAGAGTGTTTGATTCCAGCAGAAGGTAATACGCACCTTTCTCATCTATTTGCA 45535</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL087C YBL087C], [https://www.yeastgenome.org/locus/YBL088C YBL088C]
| 59406
| 59406
| Insertion
|
| T
|-
| || colspan="6" | A single nucleotide insertion was made in the intergenic region between ORFs TEL1/YBL088C and RPL23A/YBL087C.
<pre>New 59399 ATTTCCCTTTTTCTTTGAAGGCTTTTTTTTCGAATTTCCTGCTTTTTTTGCGAGGCTTTG 59458
||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||
Old 59396 ATTTCCCTTTT-CTTTGAAGGCTTTTTTTTCGAATTTCCTGCTTTTTTTGCGAGGCTTTG 59454</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL086C YBL086C], [https://www.yeastgenome.org/locus/YBL087C YBL087C]
| 61056
| 61056
| Deletion
| T
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORFs RPL23A/YBL087C and YBL086C.
<pre>New 61019 AAAAACTTGGTCTGTTGAAAATAATAACTGCATGGGTTTTT-CAAAGCAGTTGGGGGTGT 61077
||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||||
Old 61015 AAAAACTTGGTCTGTTGAAAATAATAACTGCATGGGTTTTTTCAAAGCAGTTGGGGGTGT 61074</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR205W YBR205W], [https://www.yeastgenome.org/locus/YBR207W YBR207W]
| 634934
| 634934
| Substitution
| C
| T
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs KTR3/YBR205W and FTH1/YBR207W.
<pre>New 634903 ATATACACATAATTCAATGTAGTAGCCACCTCACTTTATTCTAGTGCCTTCTTGGGTTCA 634962
|||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
Old 634898 ATATACACATAATTCAATGTAGTAGCCACCTCACTTCATTCTAGTGCCTTCTTGGGTTCA 634957</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR038W YBR038W], [https://www.yeastgenome.org/locus/YBR039W YBR039W]
| 315270
| 315271
| Substitution
| CG
| GC
|- style="height:30px; width:30px; text-align:center;"
| 315071
| 315071
| Deletion
| G
|
|-
| || colspan="6" | A single nucleotide deletion and a dinucleotide substitution were made in the intergenic region between ORFs CHS2/YBR038W and ATP3/YBR039W.
<pre>New 315050 TGTATGAGCTGGGCATCAAGAG-CTTTTGAGATTTTCCAAGTAGTAACTCATCTTTCTGA 315108
|||||||||||||||||||||| |||||||||||||||||||||||||||||||||||||
Old 315049 TGTATGAGCTGGGCATCAAGAGGCTTTTGAGATTTTCCAAGTAGTAACTCATCTTTCTGA 315108
New 315229 TCGATAAAACAAAAAAAAAGTAAGAAGATATATGAATAGGAGCTGTCGCTAGAACTAGTA 315288
||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 315229 TCGATAAAACAAAAAAAAAGTAAGAAGATATATGAATAGGACGTGTCGCTAGAACTAGTA 315288</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR036C YBR036C], [https://www.yeastgenome.org/locus/YBR037C YBR037C]
| 310457
| 310457
| Insertion
|
| T
|-
| || colspan="6" | A single nucleotide insertion was made in the intergenic region between ORFs CSG2/YBR036C and SCO1/YBR037C.
<pre>New 310430 TCCTTTAGAGTGAGAGAGCTTTTTTTTTTCTTGCGATACACCTTCGCCGGGTGATAGCCG 310489
|||||||||||||||||||||||||||| |||||||||||||||||||||||||||||||
Old 310430 TCCTTTAGAGTGAGAGAGCTTTTTTTTT-CTTGCGATACACCTTCGCCGGGTGATAGCCG 310488</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR160W YBR160W], [https://www.yeastgenome.org/locus/YBR161W YBR161W]
| 561435
| 561435
| Deletion
| C
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORFs CDC28/YBR160W and CSH1/YBR161W.
<pre>New 561405 GCAAATTCATTGCTCTTTGAATTTTGAAGAGTTTCA-TTGTCACCGTTGAATAACCGAGA 561463
|||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
Old 561399 GCAAATTCATTGCTCTTTGAATTTTGAAGAGTTTCACTTGTCACCGTTGAATAACCGAGA 561458</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2004-07-16
| [https://www.yeastgenome.org/locus/YBL066C YBL066C]
| 96812
| 96962
| Substitution
| GTGGTTGGATAGAGAACAGTGTTAG TCCCGTAGAATCGTGGTCGTTGTTC TATGATATCAACTTTGGAACAACTC AGAGGTGGATATCCCGTCTTTTAGA GGACCGGGGTCGGACGCGGAATCCA ACTGTCATATATTGACCGAAACAAA G
| GATGGTTTGGAAGTTAGAAGAAGTT ACAGTGTTAGTGCCCGTAGAAAATC GTTGGTTCGTTTTGTTGCTATTGAT ATCATTACTTTTGGAAAACAAGCTC AGAGGTGGATATGCCGTGCTTTTAG AGGAGCCGGGGTCGGAAACGACGGA ATGCAAATCTGTCATATTATTTGAC TTCGAAGCAATCG
|-
| || colspan="6" | SGD re-sequenced this region in S288C and found that 37 nucleotide insertions and 4 nucleotide changes were necessary to correct the reference sequence. As a consequence of these changes, SEF1/YBL066C was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 1,057 to 1,148 amino acids.
<pre>New: 1 TGTTTCCAGGAGTCTTCACGTTGTTTTCATTATCGATGGTTTGGAAGTTAGAAGAAGTTA 60
||||||||||||||||||||||||||||||||||| ||||| ||| ||| ||||
Current: 96777 TGTTTCCAGGAGTCTTCACGTTGTTTTCATTATCG-TGGTT-GGA---TAG-AGAA---- 96826

New: 61 CAGTGTTAGTGCCCGTAGAAAATCGTTGGTTCGTTTTGTTGCTATTGATATCATTACTTT 120
|||||||||| ||||||||| |||| || ||||| ||| ||| |||||||| |||||
Current: 96827 CAGTGTTAGT-CCCGTAGAA--TCGT-GG-TCGTT--GTT-CTA-TGATATCA--ACTTT 96875

New: 121 TGGAAAACAAGCTCAGAGGTGGATATGCCGTGCTTTTAGAGGAGCCGGGGTCGGAAACGA 180
|||| ||| ||||||||||||||| |||| ||||||||||| ||||||||||| ||
Current: 96876 -GGAA--CAA-CTCAGAGGTGGATATCCCGT-CTTTTAGAGGA-CCGGGGTCGGA--CG- 96926

New: 181 CGGAATGCAAATCTGTCATATTATTTGACTTCGAAGCAATCGGTGTACGTGAATGGGACA 240
|||||| ||| ||||||||| | ||||| |||| ||| |||||||||||||||||||
Current: 96927 CGGAATCCAA--CTGTCATAT-A-TTGAC--CGAAACAAA-GGTGTACGTGAATGGGACA 96979 </pre>
|- style="height:30px; width:30px; text-align:center;"
| 2004-07-13
| [https://www.yeastgenome.org/locus/YBL067C YBL067C]
| 93899
| 93899
| Insertion
|
| A
|-
| || colspan="6" | The work of Kellis et al. 2003 predicted the insertion of a single nucleotide; this sequence error was confirmed in S288C by SGD. As a consequence of this sequence change, UBP13/YBL067C was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 688 to 747 amino acids.
<pre>New: 93883 TCGCTTTATAAAACAAAACATATGCTGTTGCCATATTTGGAGATTCACCTGTGAATTCTA 93942
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old: 93883 TCGCTTTATAAAACAAA-CATATGCTGTTGCCATATTTGGAGATTCACCTGTGAATTCTA 93941 </pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| 2004-07-12
| [https://www.yeastgenome.org/locus/YBR062C YBR062C]
| 366383
| 366383
| Deletion
| T
|
|-
| || colspan="6" | The work of Cliften et al. 2003 predicted that there is a sequencing error in YBR062C: an single nucleotide should be deleted 100 nt upstream of the currently annotated start site. Assuming this sequence change, Cliften et al. further propose a new intron and 5' exon, and a framechange for this ORF. When spliced, this ORF would now encode a predicted protein of 180 amino acids. This sequence error was confirmed in S288C by SGD and the coordinates have been changed accordingly (start was moved upstream 195 nt and an intron was added at relative coordinates 17-98).
<pre> New: AAAGTTTTGAAATAGACCTTGCAGTTGGGATCT-GACCTGTCTTCTCTGCTCCTCCTGTG
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||
Old: AAAGTTTTGAAATAGACCTTGCAGTTGGGATCTTGACCTGTCTTCTCTGCTCCTCCTGTG </pre>
Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|- style="height:30px; width:30px; text-align:center;"
| 2004-07-09
| [https://www.yeastgenome.org/locus/YBR108W YBR108W]
| 457298
| 457298
| Insertion
|
| G
|-
| || colspan="6" | The work of Kellis et al. 2003 predicted the insertion of a single G after the G at chromosomal coordinate 457298. This sequence error was confirmed in strain S288C by SGD. As a consequence of this sequence change which caused a frameshift, YBR108W was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 848 to 947 amino acids.
<pre>New: CGGTTCGAAAAAAGTGAAGGACTCTAGCCCTGTTCCCTCAGATCTAGATGAAAAATATGT
||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||
Old: CGGTTCGAAAAAAGTGAAG-ACTCTAGCCCTGTTCCCTCAGATCTAGATGAAAAATATGT</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| 2004-01-29
| [https://www.yeastgenome.org/locus/YBL097W YBL097W]
| 40900
| 40901
| Deletion
| GA
|
|-
| || colspan="6" | Kellis et al. 2003 predicted and confirmed the deletion of two nucleotides (GA) at chromosomal coordinates 40900-40901. As a consequence of this deletion, YBL097W was extended at the 5' end, altering the N-terminus and increasing the predicted protein from 728 to 754 amino acids.
<pre>New 61 TTTACCAATAGA--TCCACCATGATGGCAAATTTTGAAGAATGGATCAAAATGGCTACAG 118
|||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||
Old 40888 TTTACCAATAGAGATCCACCATGATGGCAAATTTTGAAGAATGGATCAAAATGGCTACAG 40947</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| 2004-01-29
| [https://www.yeastgenome.org/locus/YBL013W YBL013W]
| 203180
| 203180
| Insertion
|
| C
|-
| || colspan="6" | A single C nucleotide insertion was confirmed by sequencing genomic DNA from FY23 (S288C) and a D273-10B related strain; GenBank accession number for FY23 is AY490279. The stop codon of ORF YBL013W has been moved downstream, so that the ORF is now 1206 nucleotides long as opposed to the previously annotated 1182 nt.
<pre>New 1141 GGCCAGTTCATGGCGCGCCTGCGGAAAAGATGCGGCGCCCTGAGTGAAAAGTTAGTTTTC 1200
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 203163 GGCCAGTTCATGGCGCG-CTGCGGAAAAGATGCGGCGCCCTGAGTGAAAAGTTAGTTTTC 203221</pre>
|- style="height:30px; width:30px; text-align:center;"
| 2004-01-28
| [https://www.yeastgenome.org/locus/YBL006C YBL006C], [https://www.yeastgenome.org/locus/YBL006W-A YBL006W-A]
| 216785
| 216785
| Deletion
| G
|
|-
| || colspan="6" | Kellis et al. 2003 predicted and confirmed the deletion of a single nucleotide at 216785. As a consequence of this sequence change, YBL006C was extended at the 3' end, altering the C-terminus and increasing the predicted protein from 145 to 180 amino acids. In addition, YBL006W-A was extended at the 3' end, altering the C-terminus and increasing size of the predicted protein from 39 to 49 amino acids.
<pre>New 301 TCAAGTGTCGA-CTTTTCGCACCATTTCCACCGCACATTAGAATGCAAAGCTGCTCTAGA 359
||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||
Old TCAAGTGTCGACCTTTTCGCACCATTTCCACCGCACATTAGAATGCAAAGCTGCTCTAGA</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="5"| 2004-01-26
| rowspan="5"| [https://www.yeastgenome.org/locus/YBL103C-A YBL103C-A], [https://www.yeastgenome.org/locus/YBL104C YBL104C]
| 21279
| 21279
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 18364
| 18364
| Insertion
|
| G
|- style="height:30px; width:30px; text-align:center;"
| 21288
| 21288
| Insertion
|
| C
|- style="height:30px; width:30px; text-align:center;"
| 21345
| 21345
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 21347
| 21347
| Insertion
|
| A
|-
| || colspan="6" | Brachat et al. 2003 and Kellis et al. 2003 predicted and confirmed DIFFERENT sequence changes for YBL104C. Brachat et al. demonstrated the insertion of a single G nt, which extended the 3' end by 141 nt and altered the C-terminus, resulting in overlapping ORF YBL103C-A becoming part of YBL104C (Cliften et al. also predicted this change).
<pre> New: CTTCTGTCTGCATTGGATCGCGTGATTGCGTCCCATTTATTACAAAAGGTAAGTTTGACG
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Previous: 18350 CTTCTGTCTGCATTG-ATCGCGTGATTGCGTCCCATTTATTACAAAAGGTAAGTTTGACG 18408</pre>
Kellis et al. demonstrated the insertion of four separate nucleotides (a single T, a single C, and two separate As), which extended at the 5' end by 198 nt and altered the N-terminus. The inserted C (G on the opposite, coding strand) is the third nucleotide of the new ATG start codon.
<pre> New: ATTATCATATGACCAATGGGTCACTTTTTTGATGAGACCCATGTTTATTCTTCTATACGT
||||||||||||||||||||||||||||| ||||||||| ||||||||||||||||||||
Previous: 21251 ATTATCATATGACCAATGGGTCACTTTTT-GATGAGACC-ATGTTTATTCTTCTATACGT 21308
New: TCGTGATACTGCACTTACGACTACCAGTAACATCAGAATAACCATAGAGC
||||||||||||||||||||||||||||||||||||| || |||||||||
Previous: 21309 TCGTGATACTGCACTTACGACTACCAGTAACATCAGA-TA-CCATAGAGC 21356</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Brachat S, et al.''' (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45. 
[https://www.yeastgenome.org/reference/S000073670 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12844361 PubMed] | [https://genomebiology.biomedcentral.com/articles/10.1186/gb-2003-4-7-r45 Full-Text] 
Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|- style="height:30px; width:30px; text-align:center;"
| 2004-01-21
| [https://www.yeastgenome.org/locus/YBR041W YBR041W]
| 320081
| 320082
| Deletion
| CC
|
|-
| || colspan="6" | Kellis et al. 2003 and Brachat et al. 2003 independently predicted and confirmed the deletion of two C nucleotides from YBR041W. As a consequence of this change, YBR041W was extended at the 3' end, altering the C-terminus and increasing the predicted protein from 623 to 669 amino acids.
<pre> New: TCTTATGCTATGCCCCTATTTGTTAAATTTGTTGATGAAATTAAAATGACAGATAA--TC
|||||||||||||||||||||||||||||||||||||||||||||||||||||||| ||
Previous: 320025 TCTTATGCTATGCCCCTATTTGTTAAATTTGTTGATGAAATTAAAATGACAGATAACCTC 320084</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Brachat S, et al.''' (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45. 
[https://www.yeastgenome.org/reference/S000073670 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12844361 PubMed] | [https://genomebiology.biomedcentral.com/articles/10.1186/gb-2003-4-7-r45 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2004-01-20
| [https://www.yeastgenome.org/locus/YBR157C YBR157C]
| 553996
| 553996
| Insertion
|
| G
|-
| || colspan="6" | Kellis et al. 2003 predicted and confirmed the insertion of a single G nt after the C at chromosomal coordinate 553996. As a consequence of this sequence change, YBR157C was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 106 to 255 amino acids.
<pre> New: TATGGAGGAATTTCTCCTCGTTTTCACACCATCCTTGTCTCCAGGGAAAGAGTAGGTCTT
||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||
Previous: 553978 TATGGAGGAATTTCTCCTC-TTTTCACACCATCCTTGTCTCCAGGGAAAGAGTAGGTCTT 554036</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2004-01-09
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR269C YBR269C]
| 742165
| 742165
| Insertion
|
| G
|- style="height:30px; width:30px; text-align:center;"
| 742175
| 742175
| Insertion
|
| G
|-
| || colspan="6" | Kellis et al. 2003 predicted and confirmed the insertion of G after the G at chromosomal coordinate 742165, and the insertion of another G after the G at 742175. As a consequence of these sequence changes, YBR269C was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 130 to 138 amino acids. This sequence change was incorporated at MIPS prior to SGD, and was verified in strain S288C.
<pre> New: ACGAATAATCGCCGTGTCTCAACGGGTCCTGCTTGGGACCCCCAACTTCACCAGTCTTGG
||||||||||||||||||||||||| |||||||||| |||||||||||||||||||||||
Previous: 742141 ACGAATAATCGCCGTGTCTCAACGG-TCCTGCTTGG-ACCCCCAACTTCACCAGTCTTGG</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2003-09-29
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR074W YBR074W], [https://www.yeastgenome.org/locus/YBR075W YBR075W]
| 387625
| 387625
| Deletion
| G
|
|- style="height:30px; width:30px; text-align:center;"
| 387430
| 387430
| Deletion
| C
|
|-
| || colspan="6" | Due to deletion of a C after the C at position 387430 and a deletion of G after the G at position 387625, YBR074W and YBR075W were merged. After merging YBR074W (386243 - 387484 (1-1242)) and YBR075W (387793 - 389175 (1-1383)), the coordinates of the merged ORF, YBR074W, are 386243 - 389173 (1 - 2931). YBR075W is now an alias of YBR074W. These sequence changes were verified in S288c strain by SGD.
<pre>Query: 1141 TCTCGTGATAGAATGACTTGGAAATCTTATTCATGGCTATCGTGGAC-ACGCTTTCCTCT 1199
||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
Sbjct: 387383 TCTCGTGATAGAATGACTTGGAAATCTTATTCATGGCTATCGTGGACCACGCTTTCCTCT 387442
Query: 1380 AAG-CCTATCAATTATCGAATTGTTCATTATTTTATGGACCATTTTACTTTTTACGTCGA 1438
||| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 387623 AAGGCCTATCAATTATCGAATTGTTCATTATTTTATGGACCATTTTACTTTTTACGTCGA 387682</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Brachat S, et al.''' (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45. 
[https://www.yeastgenome.org/reference/S000073670 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12844361 PubMed] | [https://genomebiology.biomedcentral.com/articles/10.1186/gb-2003-4-7-r45 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2003-01-03
| [https://www.yeastgenome.org/locus/YBR098W YBR098W], [https://www.yeastgenome.org/locus/YBR100W YBR100W]
| 442868
| 442868
| Deletion
| C
|
|-
| || colspan="6" | Due to a change to the systematic sequence of chromosome II (C deletion at 442868), YBR098W and YBR100W have been merged to one single ORF of 691 aa. MMS4 is the standard name for the new, elongated ORF after merging; YBR100W and SLX2 are its aliases. The new coordinates of MMS4/YBR098W are 441473-443548, for a coding sequence of 2076 nt.
We thank Jim Brown (james.brown@stanford.edu), and Kirk Ehmsen (ktehmsen@ucdavis.edu) for reporting this sequence error on Chr II, which was verified in the FY1679 (S288c derivative) strain background by SGD.
<pre>Old: 442861 AGAAAACCGTTTTGATTCTATATTATGATGCGCAAGAATTTTTTGAACAATACACTTCAC 442920
||||||| ||||||||||||||||||||||||||||||||||||||||||||||||||||
New: 442861 AGAAAAC-GTTTTGATTCTATATTATGATGCGCAAGAATTTTTTGAACAATACACTTCAC 442919</pre>
'''Xiao W, et al.''' (1998) Mms4, a putative transcriptional (co)activator, protects Saccharomyces cerevisiae cells from endogenous and environmental DNA damage. Mol Gen Genet 257(6):614-23 
[https://www.yeastgenome.org/reference/S000044724 SGD paper] | [PubMed https://www.ncbi.nlm.nih.gov/pubmed/9604884] | [https://link.springer.com/article/10.1007%2Fs004380050689 Full-Text] 
'''Kaliraman V, et al.''' (2001) Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease. Genes Dev 15(20):2730-40 
[https://www.yeastgenome.org/reference/S000068964 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/11641278 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC312806/ Full-Text] 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Brachat S, et al.''' (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45. 
[https://www.yeastgenome.org/reference/S000073670 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12844361 PubMed] | [https://genomebiology.biomedcentral.com/articles/10.1186/gb-2003-4-7-r45 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2003-01-02
| [https://www.yeastgenome.org/locus/YBR086C YBR086C]
| 422272
| 422273
| Substitution
| TA
| AT
|-
| || colspan="6" | We received a direct notification from MIPS about the following sequence changes; we did not have this change in SGD, so the sequence was edited: The T at 422272 was changed to an A, and the A at 422273 was changed to a T. These differences changed amino acid residue 243 of IST2/YBR086C from Tyr (TAC) -> Ile (ATC). The coordinates of YBR086C are not changed due to this sequence update. References: (1) Sequence verification in FY1679 (S288c derivative strain) background by SGD, (2) Personal communication from Anna Kurlandzka (ania218@poczta.ibb.waw.pl).
<pre>Old: 422221 GTAGGCAAAAAAGACAAGATGGAAATCATTGGGCCGTTATAAATTTGCTTGTAGAAAATT 422280
||||||||||||||||||||||||||||||||||||||||||||||||||| |||||||
New: 422221 GTAGGCAAAAAAGACAAGATGGAAATCATTGGGCCGTTATAAATTTGCTTGATGAAAATT 422280</pre>
|- style="height:30px; width:30px; text-align:center;"
| 2001-05-29
| [https://www.yeastgenome.org/locus/YBL069W YBL069W]
| 91711
| 91711
| Deletion
| C
|
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II within the ORF AST1/YBL069W. The C at chromosomal coordinate 91711 was deleted, shifting the reading frame and moving the stop from 91722 to 92025:
<pre>Old: 91681 TTGATTCACGGCGGTGGTGCGTACGTAACCCACTGTAGGTGATTACGTTGCCAATTATAA 91740
|||||||||||||||||||||||||||||| |||||||||||||||||||||||||||||
New: 91681 TTGATTCACGGCGGTGGTGCGTACGTAACC-ACTGTAGGTGATTACGTTGCCAATTATAA 91739</pre>
|- style="height:30px; width:30px; text-align:center;"
| 2001-05-29
| [https://www.yeastgenome.org/locus/YBL004W YBL004W]
| 234918
| 234918
| Substitution
| C
| A
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II within the ORF UTP20/YBL004W. The C at chromosomal coordinate 234918 was changed to an A:
<pre>Old: 234901 CAGACCGTATTAGAAAGCAGAAAGGAAAGGAGATCTAAAAGGGCAATTCTGGCTGTTAAC 234960
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
New: 234901 CAGACCGTATTAGAAAGAAGAAAGGAAAGGAGATCTAAAAGGGCAATTCTGGCTGTTAAC 234960</pre>
|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 1999-04-26
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR266C YBR266C], [https://www.yeastgenome.org/locus/YBR267W YBR267W]
| 739912
| 739912
| Deletion
| A
|
|- style="height:30px; width:30px; text-align:center;"
| 739866
| 739866
| Deletion
| G
|
|-
| || colspan="6" | Two changes were made to the systematic sequence of Chromosome II within the ORF REI1/YBR267W. The G at chromosomal coordinate 739866 was deleted, and the A at 739912 was deleted; as a result, the start of YBR267W was moved 294 nt upstream.
Note that the deletion at 739912 also affects the overlapping ORF SLM6/YBR266C; as a result, the stop of YBR266C was moved 111 nt upstream:
<pre>Old: 739860 GAGCAGGCGGGCCCACATGAAGTCCGATTGGCATCGCTACAATTTGAAAAGAACGTGTTG 739919
|||||| ||||||||||||||||||||||||||||||||||||||||||||| |||||||
New: 739860 GAGCAG-CGGGCCCACATGAAGTCCGATTGGCATCGCTACAATTTGAAAAGA-CGTGTTG 739917</pre>
|- style="height:30px; width:30px; text-align:center;"
| 1999-04-26
| [https://www.yeastgenome.org/locus/YBR201W YBR201W]
| 623651
| 623651
| Deletion
| A
|
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II in the region upstream of the ORF DER1/YBR201W. The A at chromosomal coordinate 623651 was deleted. As a result, the start of YBR201W was moved upstream 210 nucleotides, increasing the size of the predicted protein from 141 to 211 amino acids.
<pre>Old: 623640 GATCCAGGGAAAGGTAGTGTACAGTTATGATTTAGTATTCAAAAAGGGACAATATGGAAG 623699
||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||
New: 623640 GATCCAGGGAA-GGTAGTGTACAGTTATGATTTAGTATTCAAAAAGGGACAATATGGAAG 623698</pre>
|- style="height:30px; width:30px; text-align:center;"
| 1999-04-26
| [https://www.yeastgenome.org/locus/YBR294W YBR294W]
| 791709
| 791709
| Substitution
| T
| C
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II within the ORF SUL1/YBR294W. The T at chromosomal coordinate 791709 was changed to a C:
<pre>Old: 791700 TATGTGCTGTAACTGGGACAAATTTACCGTTTTTTCATATCGATATACCCGATTTTTCTA 791759
||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||||
New: 791700 TATGTGCTGCAACTGGGACAAATTTACCGTTTTTTCATATCGATATACCCGATTTTTCTA 791759</pre>
|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 1999-04-26
| rowspan="3"| [https://www.yeastgenome.org/locus/YBR069C YBR069C], [https://www.yeastgenome.org/locus/YBR070C YBR070C]
| 378824
| 378824
| Insertion
|
| C
|- style="height:30px; width:30px; text-align:center;"
| 378810
| 378810
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 378815
| 378815
| Deletion
| C
|
|-
| || colspan="6" | Three changes were made to the systematic sequence of Chromosome II in the intergenic region between the ORFs TAT1/YBR069C and ALG14/YBR070C. A single T was inserted after the T at chromosomal coordinate 378810, the C at 378815 was deleted, and a C was inserted after the G at 378824:
<pre>Old: 378781 GCCGGCCCTGACTGACCTTTTTTGTATTTT-GGCCCGTCCCGGCG-GGCGAAGAGTGAGAC 378839
|||||||||||||||||||||||||||||| |||| ||||||||| |||||||||||||||
New: 378781 GCCGGCCCTGACTGACCTTTTTTGTATTTTTGGCC-GTCCCGGCGCGGCGAAGAGTGAGAC 378840</pre>
|- style="height:30px; width:30px; text-align:center;"
| 1999-04-23
| [https://www.yeastgenome.org/locus/YBL067C YBL067C]
| 94040
| 94040
| Substitution
| G
| C
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II within the ORF UBP13/YBL067C. The G at chromosomal coordinate 94040 was changed to a C:
<pre>Old: 94021 CATAATGGCCGTGTTGTGGGCCACCGCCCATATGAACGACAATCCCAGCCAATTCATACT 94080
||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||
New: 94021 CATAATGGCCGTGTTGTGGCCCACCGCCCATATGAACGACAATCCCAGCCAATTCATACT 94080</pre>
|- style="height:30px; width:30px; text-align:center;"
| rowspan="4"| 1999-04-23
| rowspan="4"| [https://www.yeastgenome.org/locus/YBR006W YBR006W]
| 247367
| 247367
| Substitution
| C
| T
|- style="height:30px; width:30px; text-align:center;"
| 248539
| 248539
| Substitution
| A
| T
|- style="height:30px; width:30px; text-align:center;"
| 248278
| 248278
| Substitution
| A
| T
|- style="height:30px; width:30px; text-align:center;"
| 247262
| 247262
| Substitution
| C
| G
|-
| || colspan="6" | Three single nucleotide (nt) substitutions were made to the systematic sequence of Chromosome II within the ORF UGA2/YBR006W, and one substitution was made in the adjacent intergenic region. The C at chromosomal coordinate 247262 was changed to a G, the C at 247367 was changed to a T, the A at 248278 was changed to a T (destroying the stop codon), and the A at 248539 was changed to a T. As a result, the stop was moved 186 nucleotides downstream, increasing the size of the coding sequence from 1308 nt to 1494 nt.
<pre>Old: 247261 TCGCAACCATCATTACTTTAGAAAATGGTAAAGCTCTAGGGGAAGCTAAAGGAGAAATCA 247320
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
New: 247261 TGGCAACCATCATTACTTTAGAAAATGGTAAAGCTCTAGGGGAAGCTAAAGGAGAAATCA 247320
Old: 247321 AATACGCGGCTTCGTATTTTGAGTGGTACGCCGAGGAAGCACCCCGCTTATATGGTGCTA 247380
|||||||||||||||||||||||||||||||||||||||||||||| |||||||||||||
New: 247321 AATACGCGGCTTCGTATTTTGAGTGGTACGCCGAGGAAGCACCCCGTTTATATGGTGCTA 247380
Old: 248221 CTAATGATACTGAGTTTGGTTTAGCAGCATATGTCTTTTCTAAAAATGTCAACACTTAAT 248280
||||||||||||||||||||||||||||||||||||||||||||||||||||||||| ||
New: 248221 CTAATGATACTGAGTTTGGTTTAGCAGCATATGTCTTTTCTAAAAATGTCAACACTTTAT 248280
Old: 248521 GTATATATCTATTGCATGAATAAATACTCTACTCCTCGTATATAGAAAGTTAAGTAAATT 248580
|||||||||||||||||| |||||||||||||||||||||||||||||||||||||||||
New: 248521 GTATATATCTATTGCATGTATAAATACTCTACTCCTCGTATATAGAAAGTTAAGTAAATT 248580</pre>
|- style="height:30px; width:30px; text-align:center;"
| 1999-04-23
| [https://www.yeastgenome.org/locus/YBL066C YBL066C]
| 97484
| 97485
| Substitution
| TG
| GC
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II within the ORF SEF1/YBL066C. The two nucleotides TG at positions 575 and 576 (chromosomal coordinates 97484-97485) were changed to GC, altering translation by changing amino acid 192 from Gln (CAA) to Ala (GCA). Note that this ORF is on the Crick strand.
<pre>Old: 97441 AGAACCGTCAGAATCTCCGTTATTTGTCTTGGCTAGCTTTTCTTGCTGCTTTAAGGCATT 97500
||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
New: 97441 AGAACCGTCAGAATCTCCGTTATTTGTCTTGGCTAGCTTTTCTGCCTGCTTTAAGGCATT 97500</pre>
'''Cherry JM, et al.''' (1998) "Genetic and Physical Maps of Saccharomyces cerevisiae (Edition 15)". Pp. 414-420 in 1998 Yeast Genetics and Molecular Biology Meeting Program and Abstracts. Bethesda, MD: The Genetics Society of America 
[https://www.yeastgenome.org/reference/S000076263 SGD paper]

|- style="height:30px; width:30px; text-align:center;"
| 1999-04-22
| [https://www.yeastgenome.org/locus/YBL033C YBL033C]
| 159114
| 159114
| Substitution
| C
| G
|-
| || colspan="6" | The C at chromosomal coordinate 159114 within the ORF RIB1/YBL033C was changed to a G, altering translation by changing amino acid 181 from Lys (AAG) to Asn (AAC). Note that this ORF is on the Crick strand:
<pre>Old: 159061 CGACCCTCTTGTCTTAGATACACGATAACACCATGGCCGTTTCCACCTTTGATCTTGCTT 159120
||||||||||||||||||||||||||||||||||||||||||||||||||||| ||||||
New: 159061 CGACCCTCTTGTCTTAGATACACGATAACACCATGGCCGTTTCCACCTTTGATGTTGCTT 159120</pre>
'''Cherry JM, et al.''' (1998) "Genetic and Physical Maps of Saccharomyces cerevisiae (Edition 15)". Pp. 414-420 in 1998 Yeast Genetics and Molecular Biology Meeting Program and Abstracts. Bethesda, MD: The Genetics Society of America 
[https://www.yeastgenome.org/reference/S000076263 SGD paper]

|- style="height:30px; width:30px; text-align:center;"
| rowspan="6"| 1998-09-13
| rowspan="6"| [https://www.yeastgenome.org/locus/YBL101C YBL101C]
| 25408
| 25408
| Insertion
|
| C
|- style="height:30px; width:30px; text-align:center;"
| 28272
| 28272
| Insertion
|
| G
|- style="height:30px; width:30px; text-align:center;"
| 28296
| 28296
| Insertion
|
| C
|- style="height:30px; width:30px; text-align:center;"
| 25394
| 25394
| Deletion
| T
|
|- style="height:30px; width:30px; text-align:center;"
| 28306
| 28306
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 28302
| 28302
| Insertion
|
| GG
|-
| || colspan="6" | Six changes were made to the systematic sequence of Chromosome II within the ORF ECM21/YBL101C and in the adjacent intergenic region. Within the ORF, the T at chromosomal coordinate 25394 was deleted, and a single C was inserted after the C at 25408:
<pre>Old: 25381 CGGCATCATCGCTTGTATCCGGATGGCC-ACTAACTGACGTAGTTCTTGATAAGTTCAAT 25439
||||||||||||| |||||||||||||| |||||||||||||||||||||||||||||||
New: 25381 CGGCATCATCGCT-GTATCCGGATGGCCCACTAACTGACGTAGTTCTTGATAAGTTCAAT 25439</pre>
Upstream of the ORF, a single G was inserted after the G at 28272, a single C was inserted after the C at 28296, two nucleotides (nt) GG were inserted after the G at 28302, and the A at 28306 was changed to a G:
<pre>Old: 28260 TTTTTCGCCACCG-TCTTGATGTTATAAACGGCATGCC-AATAGG--TAGAGAAAAATCT 28315
||||||||||||| |||||||||||||||||||||||| |||||| ||| |||||||||
New: 28260 TTTTTCGCCACCGGTCTTGATGTTATAAACGGCATGCCCAATAGGGGTAGGGAAAAATCT 28319</pre>
The start site of YBL101C was then moved upstream, extending the size of the coding region from 3234 nt to 3354 nt, and the size of the predicted protein from 728 amino acids (aa) to 754 aa.

|- style="height:30px; width:30px; text-align:center;"
| 1997-07-27
| [https://www.yeastgenome.org/locus/YBL091C YBL091C]
| 48615
| 48615
| Substitution
| A
| C
|-
| || colspan="6" | The A at chromosomal coordinate 48615 (upstream of the Crick strand ORF MAP2/YBL091C at coordinates 48402-47353) was changed to a C, and the start site of YBL091C was then moved 216 nucleotides (nt) upstream to the newly-created start codon, extending the size of the coding sequence from 1050 nt to 1266 nt, the size of the predicted protein from 349 amino acids (aa) to 421 aa. Note that the sequence presented below is from the Watson strand:
<pre>New: 48600 TATTTCAGCGTCTGTCATTTTTCAATACGGTAGAGCTTCTACAGTACTTGTTGATGTAAA 48659
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Old: 48600 TATTTCAGCGTCTGTAATTTTTCAATACGGTAGAGCTTCTACAGTACTTGTTGATGTAAA 48659</pre>
|- style="height:30px; width:30px; text-align:center;"
| 1997-07-27
| [https://www.yeastgenome.org/locus/YBL103C YBL103C]
| 22603
| 22603
| Insertion
|
| G
|-
| || colspan="6" | A single G was inserted after the G at chromosomal coordinate 22603 within the ORF RTG3/YBL103C, shifting the frame and extending the 3' end by 510 nucleotides:
<pre>New: 22561 TACCTAGGTCATCGTAATTCAATAAAGATGGTGGAACCAACTGGCCGAGTTCTTTTATCT 22620
||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||
Old: 22561 TACCTAGGTCATCGTAATTCAATAAAGATGGTGGAACCAACTG-CCGAGTTCTTTTATCT 22619</pre>
|}

=Annotation Changes ''without sequence changes''=
{| class="wikitable" style="border-spacing: 2px; border: 1px solid darkgray;"
! Date !! Affected Features
|-
| 2014-11-18|| TLC1
|-
| || style="border: 1px solid darkgray;" |The feature_type annotation of TLC1 was changed from ncRNA to telomerase_RNA_gene (SO:0001643) as part of SGD's genome annotation revision R64.2.
|-
| 2014-11-18|| ARS207, ARS208, ARS209, ARS211, ARS214, ARS216, ARS217, ARS224, ARS231
|-
| || style="border: 1px solid darkgray;" |As part of SGD's genome annotation revision R64.2, new ARS consensus sequences were annotated within the following ARS elements on Chromosome II based on Liachko et al. 2013: ARS207, ARS231, ARS208, ARS209, ARS211, ARS214, ARS216, ARS217, ARS224.
Liachko I, et al. (2013) High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast. Genome Res 23(4):698-704

|-
| 2014-11-18|| ARS202, ARS207, ARS208, ARS209, ARS214, ARS224, ARS228, ARS231
|-
| || style="border: 1px solid darkgray;" |The chromosomal coordinates of the following ARS elements on Chromosome II were updated based on Liachko et al. 2013 as part of SGD's genome annotation revision R64.2: ARS202, ARS207, ARS231, ARS208, ARS209, ARS214, ARS224, ARS228.
Liachko I, et al. (2013) High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast. Genome Res 23(4):698-704

|-
| 2014-11-18|| ARS200, ARS201, ARS203, ARS206, ARS217
|-
| || style="border: 1px solid darkgray;" |The following new ARS elements on Chromosome II were added to the genome annotation based on Liachko et al. 2013 as part of SGD's genome annotation revision R64.2: ARS200, ARS201, ARS203, ARS206, ARS217.
Liachko I, et al. (2013) High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast. Genome Res 23(4):698-704

|-
| 2014-11-18|| ETC8
|-
| || style="border: 1px solid darkgray;" |The following previously unmapped features were identified as nuclear matrix attachment sites and assigned chromosomal coordinates based on Hiraga et al. 2012 as part of SGD's genome annotation revision R64.2: ETC1, ETC2, ETC3, ETC4, ETC6, ETC7, ETC8.
Hiraga SI, et al. (2012) TFIIIC localizes budding yeast ETC sites to the nuclear periphery. Mol Biol Cell 23(14):2741-54

|-
| 2009-05-07|| YBR073W
|-
| || style="border: 1px solid darkgray;" |The start site for RDH54/YBR073W was reinstated 102 nt (34 codons) upstream. This is a reversal of the start site change made to this ORF on 2003-09-22. Thank you to Nancy Hollingsworth for bringing this issue to our attention.
Shinohara M, et al. (1997) Characterization of the roles of the Saccharomyces cerevisiae RAD54 gene and a homologue of RAD54, RDH54/TID1, in mitosis and meiosis. Genetics 147(4):1545-56

Petukhova G, et al. (2000) Promotion of Rad51-dependent D-loop formation by yeast recombination factor Rdh54/Tid1. Genes Dev 14(17):2206-15

Chi P, et al. (2006) Yeast recombination factor Rdh54 functionally interacts with the Rad51 recombinase and catalyzes Rad51 removal from DNA. J Biol Chem 281(36):26268-79

Kwon Y, et al. (2008) ATP-dependent Chromatin Remodeling by the Saccharomyces cerevisiae Homologous Recombination Factor Rdh54. J Biol Chem 283(16):10445-52

|-
| 2009-05-07|| ARS212, ARS213, ARS221
|-
| || style="border: 1px solid darkgray;" |The following ARS elements on Chromosome 2 were added to the genome annotation based on Raveendranathan et al. 2006: ARS212, ARS213, and ARS221.
Raveendranathan M, et al. (2006) Genome-wide replication profiles of S-phase checkpoint mutants reveal fragile sites in yeast. EMBO J 25(15):3627-39

|-
| 2007-07-09|| YBR215W
|-
| || style="border: 1px solid darkgray;" |The start of ORF HPC2/YBR215W was moved 90 nt upstream and an intron was added at relative coordinates 14..97 based on GenBank EF123149 and Juneau et al. 2007. According to Juneau et al. 2007, the intron is "inefficiently spliced" (splicing rate 85%). The ORF had been annotated as 1872 nt long, but is now 1962 nt in length.
Juneau K, et al. (2007) High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing. Proc Natl Acad Sci U S A 104(5):1522-7

|-
| 2007-04-05|| YBLCdelta7, YBRCdelta11, YBRCdelta14, YBRCdelta19
|-
| || style="border: 1px solid darkgray;" |The following Ty1 LTRs on Chromosome II were mistakenly annotated on the wrong strand (i.e., on Watson instead of Crick); the error has now been corrected, so that the LTRs are annotated on the Crick strand: YBLCdelta7, YBRCdelta11, YBRCdelta14, YBRCdelta19.
|-
| 2007-04-05|| YBRCtau2
|-
| || style="border: 1px solid darkgray;" |YBRWtau2, a Ty4 LTR on Chromosome II, was mistakenly annotated on the wrong strand (i.e., on Watson instead of Crick). Both the orientation and the feature name have been corrected, so that the LTR now has the systematic name YBRCtau2 and is annotated on the Crick strand. The name YBRWtau2 is being retained as an alias.
|-
| 2007-04-05|| YBLCtau1
|-
| || style="border: 1px solid darkgray;" |YBLWtau1, a Ty4 LTR on Chromosome II, was mistakenly annotated on the wrong strand (i.e., on Watson instead of Crick). Both the orientation and the feature name have been corrected, so that the LTR now has the systematic name YBLCtau1 and is annotated on the Crick strand. The name YBLWtau1 is being retained as an alias.
|-
| 2007-04-04|| YBR089C-A
|-
| || style="border: 1px solid darkgray;" |NHP6B/YBR089C-A mRNA contains an intron in the 5' untranslated region (UTR).
Miura F, et al. (2006) A large-scale full-length cDNA analysis to explore the budding yeast transcriptome. Proc Natl Acad Sci U S A 103(47):17846-51

Juneau K, et al. (2007) High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing. Proc Natl Acad Sci U S A 104(5):1522-7

|-
| 2007-04-04|| YBL092W
|-
| || style="border: 1px solid darkgray;" |RPL32/YBL092W mRNA contains an intron in the 5' untranslated region (UTR).
Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

Miura F, et al. (2006) A large-scale full-length cDNA analysis to explore the budding yeast transcriptome. Proc Natl Acad Sci U S A 103(47):17846-51

Juneau K, et al. (2007) High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing. Proc Natl Acad Sci U S A 104(5):1522-7

|-
| 2007-04-04|| YBL072C
|-
| || style="border: 1px solid darkgray;" |RPS8A/YBL072C mRNA contains an intron in the 5' untranslated region (UTR).
Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

Miura F, et al. (2006) A large-scale full-length cDNA analysis to explore the budding yeast transcriptome. Proc Natl Acad Sci U S A 103(47):17846-51

Juneau K, et al. (2007) High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing. Proc Natl Acad Sci U S A 104(5):1522-7

|-
| 2006-10-04|| LSR1
|-
| || style="border: 1px solid darkgray;" |The start site and the stop site for LSR1/snR20 (aka U2 snRNA) were each moved 4 nt upstream, to the positions determined by Ares M. Jr. (1986). Thanks to Wayne Decatur for bringing this update to our attention.
Ares M Jr (1986) U2 RNA from yeast is unexpectedly large and contains homology to vertebrate U4, U5, and U6 small nuclear RNAs. Cell 47(1):49-59

|-
| 2006-10-02|| ARS230, ARS231
|-
| || style="border: 1px solid darkgray;" |ARS230 (also known as ARS201.5) and ARS231 (also known as ARS207.5) were added to the genome annotation based on Nieduszynski et al. 2006.
Nieduszynski CA, et al. (2006) Genome-wide identification of replication origins in yeast by comparative genomics. Genes Dev 20(14):1874-9

|-
| 2006-09-07|| ARS202, ARS207, ARS208, ARS211, ARS214, ARS215, ARS216, ARS220, ARS222, ARS224, ARS225, ARS228
|-
| || style="border: 1px solid darkgray;" |The following ARS elements on Chromosome II were added to SGD based on Nieduszynski et al. 2006: ARS202, ARS207, ARS208, ARS211, ARS214, ARS215, ARS216, ARS220, ARS222, ARS224, ARS225, ARS228.
Nieduszynski CA, et al. (2006) Genome-wide identification of replication origins in yeast by comparative genomics. Genes Dev 20(14):1874-9

|-
| 2006-03-02|| ARS209
|-
| || style="border: 1px solid darkgray;" |This new ARS element ARS209 was added to the genome annotation based on Bouton & Smith 1986 and Wyrick et al. 2001.
Wyrick JJ, et al. (2001) Genome-wide distribution of ORC and MCM proteins in S. cerevisiae: high-resolution mapping of replication origins. Science 294(5550):2357-60

Bouton AH and Smith MM (1986) Fine-structure analysis of the DNA sequence requirements for autonomous replication of Saccharomyces cerevisiae plasmids. Mol Cell Biol 6(7):2354-63

|-
| 2005-11-10|| snR161
|-
| || style="border: 1px solid darkgray;" |New snoRNA, snR161, added based on the work of Olivas et al. 1997 and Schattner et al. 2004. Note that Olivas et al. refer to this snoRNA as RNA161.
Olivas WM, et al. (1997) Analysis of the yeast genome: identification of new non-coding and small ORF-containing RNAs. Nucleic Acids Res 25(22):4619-25

Schattner P, et al. (2004) Genome-wide searching for pseudouridylation guide snoRNAs: analysis of the Saccharomyces cerevisiae genome. Nucleic Acids Res 32(14):4281-96

|-
| 2005-11-08|| YBR056C-B, YBR201C-A
|-
| || style="border: 1px solid darkgray;" |Based on comparisons of the genome sequences of six Saccharomyces species, Cliften et al. 2003 suggested that two new ORFs, YBR056C-B and YBR201C-A, be added to the S. cerevisiae genome annotation.
Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2005-11-07|| YBR286W
|-
| || style="border: 1px solid darkgray;" |After consultation with MIPS, SGD will incorporate the annotation change suggested by Kellis et al. 2003 for APE3/YBR286W. The start site is being moved 78 nt downstream from chromosomal coordinate 774618 to 774696, resulting in a predicted protein of 537 aa, as opposed to the previously annotated 563 aa. The 1692-nt ORF is now 1614 nt.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

|-
| 2004-10-12|| CEN2
|-
| || style="border: 1px solid darkgray;" |Centromeric DNA elements CDEI, CDEII, and CDEIII were annotated based on Wieland et al. 2001 and Espelin et al. 2003.
Wieland G, et al. (2001) Determination of the binding constants of the centromere protein Cbf1 to all 16 centromere DNAs of Saccharomyces cerevisiae. Nucleic Acids Res 29(5):1054-60

Espelin CW, et al. (2003) Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII. Mol Biol Cell 14(11):4557-68

|-
| 2004-04-01|| RUF8
|-
| || style="border: 1px solid darkgray;" |Feature annotation removed per John McCutcheon and Sean Eddy.
McCutcheon J and Eddy S (2004) Corrigendum: Computational identification of non-coding RNAs in Saccharomyces cerevisiae by comparative genomics Nucleic Acids Res 32 (15):4713

|-
| 2004-04-01|| YBR230W-A
|-
| || style="border: 1px solid darkgray;" |ORF identified by John McCutcheon and Sean Eddy.
McCutcheon JP and Eddy SR (2003) Computational identification of non-coding RNAs in Saccharomyces cerevisiae by comparative genomics. Nucleic Acids Res 31(14):4119-28

|-
| 2004-01-07|| YBL091C-A
|-
| || style="border: 1px solid darkgray;" |Based on comparison to related fungi, Brachat et al., Blandin et al., and Cliften et al. all proposed an intron and 5' extension for YBL091C-A. The resulting ORF is in the same frame with the start codon shifted 316 bp upstream; the protein has a 76-residue extension at the N-terminus.
Blandin G, et al. (2000) Genomic exploration of the hemiascomycetous yeasts: 4. The genome of Saccharomyces cerevisiae revisited. FEBS Lett 487(1):31-6

Brachat S, et al. (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-12-17|| YBR111W-A
|-
| || style="border: 1px solid darkgray;" |The size of the first intron of YBR111W-A was increased and a second intron was added on the basis of conserved splice sites predicted by Cliften et al. 2003, as well as subsequent experimental evidence (GenBank AY278445). The chromosomal coordinates of the coding sequence have changed from 462094-462172..462175-462392 to 462094-462164..462245-462384..462455-462534.
Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-12-17|| YBR255C-A
|-
| || style="border: 1px solid darkgray;" |The boundaries of the intron in ORF YBR255C-A were shifted by 1 bp on 5' end and 2 bp on 3' end on basis of conserved splice sites in other fungal species as predicted by Blandin et al. 2000.
Blandin G, et al. (2000) Genomic exploration of the hemiascomycetous yeasts: 4. The genome of Saccharomyces cerevisiae revisited. FEBS Lett 487(1):31-6

|-
| 2003-09-22|| YBR280C
|-
| || style="border: 1px solid darkgray;" |The start site for YBR280C was moved 15 nt (5 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBR172C
|-
| || style="border: 1px solid darkgray;" |The start site for SMY2/YBR172C was moved 150 nt (50 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBL089W
|-
| || style="border: 1px solid darkgray;" |The start site for AVT5/YBL089W was moved 150 nt (50 codons) downstream based on the automated comparison of closely related Saccharomyces species by Kellis et al. 2003. The numbering for both the nucleotides in the DNA coding sequence and the amino acids in the predicted protein have been updated. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBL068W
|-
| || style="border: 1px solid darkgray;" |The start site for PRS4/YBL068W was moved 84 nt (28 codons) downstream based on the automated comparison of closely related Saccharomyces species by Kellis et al. 2003. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBR095C
|-
| || style="border: 1px solid darkgray;" |The start site for YBR095C was moved 69 nt (23 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBR073W
|-
| || style="border: 1px solid darkgray;" |The start site for RDH54/YBR073W was moved 102 nt (34 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBR058C
|-
| || style="border: 1px solid darkgray;" |The start site for UBP14/YBR058C was moved 66 nt (22 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBR122C
|-
| || style="border: 1px solid darkgray;" |The start site for MRPL36/YBR122C was moved 57 nt (19 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine; 3) The predicted protein translated from the conserved methionine contains a predicted mitochondrial targeting signal sequence (using both MitoProt (MIPS) and Predotar), while the predicted protein translated from the previously annotated S. cerevisiae start codon does not.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBR264C
|-
| || style="border: 1px solid darkgray;" |The start site for YPT10/YBR264C was moved 57 nt (19 codons) downstream based on the automated comparison of closely-related Saccharomyces species by Kellis et al. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBR263W
|-
| || style="border: 1px solid darkgray;" |The start site for SHM1/YBR263W was moved 225 nt (75 codons) downstream based on the automated comparison of closely-related Saccharomyces species by Kellis et al. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-09|| TEL02L, TEL02R
|-
| || style="border: 1px solid darkgray;" |The chromosomal locations for the following telomeric elements on Chromosome 2 were generously provided by Ed Louis and Dave Barton (University of Leicester, UK): TEL02L, TEL02L-XC, TEL02L-XR, TEL02L-YP, TEL02R, TEL02R-XC, TEL02R-XR, TEL02R-TR.

Note that TEL02L does have telomeric repeats (TEL02L-TR), but they are missing from the genome annotation due to sequencing difficulties encountered during the initial genome sequencing efforts in the 1990s.
|-
| 2003-07-29|| YBL039C-A, YBR121C-A, YBR196C-B, YBR221W-A
|-
| || style="border: 1px solid darkgray;" |Thanks to Oshiro et al., Velculescu et al., and Basrai et al. for providing the coordinates of the following four ORFs on Chromosome 2: YBL039C-A, YBR121C-A, YBR196C-B, YBR221W-A.
Basrai MA, et al. (1999) NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae. Mol Cell Biol 19(10):7041-9

Velculescu VE, et al. (1997) Characterization of the yeast transcriptome. Cell 88(2):243-51

Oshiro G, et al. (2002) Parallel identification of new genes in Saccharomyces cerevisiae. Genome Res 12(8):1210-20

|-
| 2003-07-29|| YBR056W-A, YBR109W-A, YBR126W-B
|-
| || style="border: 1px solid darkgray;" |Thanks to MIPS for providing the coordinates of the following three ORFs on Chromosome 2: YBR056W-A, YBR109W-A, YBR126W-B.
|-
| 2003-07-29|| YBL006W-A, YBL071C-B, YBL100W-C, YBL113W-A, YBR126W-A, YBR131C-A, YBR141W-A, YBR182C-A, YBR223W-A, YBR296C-A, YBR298C-A
|-
| || style="border: 1px solid darkgray;" |Thanks to Kumar et al. for providing the coordinates of the following 11 ORFs on Chromosome 2: YBL006W-A, YBL071C-B, YBL101W-C, YBL113W-A, YBR126W-A, YBR131C-A, YBR141W-A, YBR182C-A, YBR223W-A, YBR296C-A, YBR298C-A.
Kumar A, et al. (2002) An integrated approach for finding overlooked genes in yeast. Nat Biotechnol 20(1):58-63

|-
| 2003-07-29|| YBL008W-A, YBL068W-A, YBL103C-A, YBR072C-A, YBR076C-A, YBR196C-A, YBR200W-A
|-
| || style="border: 1px solid darkgray;" |Thanks to Kessler et al. for providing the coordinates of the following seven ORFs on Chromosome 2: YBL008W-A, YBL068W-A, YBL103C-A, YBR072C-A, YBR076C-A, YBR196C-A, YBR200W-A.
Kessler MM, et al. (2003) Systematic discovery of new genes in the Saccharomyces cerevisiae genome. Genome Res 13(2):264-71

|-
| 2003-07-29|| YBL039W-B, YBR111W-A
|-
| || style="border: 1px solid darkgray;" |Thanks to Brachat et al. for providing the coordinates of the following two ORFs on Chromosome 2 based on homology to Ashbya gossypii: YBL039W-B, YBR111W-A.
Brachat S, et al. (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45

|-
| 2003-03-06|| RUF8
|-
| || style="border: 1px solid darkgray;" |Thanks to John McCutcheon and Sean Eddy for providing the coordinates for the following RNA features: SNR82, SNR83, SNR84, RUF4, RUF5-1, RUF5-2, RUF6, RUF7, and RUF8.
McCutcheon JP and Eddy SR (2003) Computational identification of non-coding RNAs in Saccharomyces cerevisiae by comparative genomics. Nucleic Acids Res 31(14):4119-28

|-
| 2001-01-30|| YBL071W-A
|-
| || style="border: 1px solid darkgray;" |ORF added based on similarity to an S. pombe gene (information submitted by Valerie Wood).
|-
| 2000-08-11|| YBR089C-A
|-
| || style="border: 1px solid darkgray;" |old name: YBR090C-A; new name: YBR089C-A; date: 11/1998; old coord: ChrII 426447 426148; SGDID: S0002157; Name changed due to nomenclature
|-
| 2000-07-14|| YBR186W
|-
| || style="border: 1px solid darkgray;" |Davis et al. demonstrated an intron and 3' exon in PCH2/YBR186W that were not previously annotated. The addition of this intron and exon alters the C-terminus of the protein product and increases the protein size from 537 to 564 amino acids.
Davis CA, et al. (2000) Test of intron predictions reveals novel splice sites, alternatively spliced mRNAs and new introns in meiotically regulated genes of yeast. Nucleic Acids Res 28(8):1700-6

|-
| 1999-11-17|| YBL059C-A
|-
| || style="border: 1px solid darkgray;" |A new ORF, YBL059C-A, was identified from EST analysis (Evan Hurowitz in Pat Brown's lab).
|-
| 1998-05-21|| YBL091C-A, YBL107W-A
|-
| || style="border: 1px solid darkgray;" |The following 27 ORFs were added to the genome annotation based on Velculescu et al. 1997: YBL091C-A, YBL107W-A, YCR018C-A, YCR102W-A, YDL130W-A, YDR034C-A, YDR034W-B, YDR363W-A, YDR525W-A, YER048W-A, YER091C-A, YER138W-A, YGR122C-A, YIR020W-B, YKL033W-A, YKL053C-A, YKL162C-A, YLL018C-A, YLR262C-A, YML081C-A, YMR046W-A, YMR158C-B, YMR194C-A, YNR032C-A, YOL013W-A, YOR298C-A, and YPR002C-A.

|}

Chromosome II History

2019-10-02T20:48:32Z

Pcng:

This page lists all sequence and annotation changes that have been made to the Chromosome II systematic reference sequence since its intial release on 1996-07-31. 
*The sequence of Chromosome II has been updated '''192''' times, affecting '''122''' features. 
*The annotation of Chromosome II has been updated '''49''' times, affecting '''88''' features. 
Current and past versions can be obtained from SGD's [https://www.yeastgenome.org/downloads Download site].

__FORCETOC__

=Sequence Changes=

{|border="1" style="border-collapse:collapse; width:90%" cellpadding="6"
! Date !! Affected Features !! Start Coordinate of Change !! End Coordinate of Change !! Type of Change !! Old Sequence !! New Sequence
|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBR068C YBR068C]
| 375081
| 375081
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 375272
| 375272
| Substitution
| T
| A
|- style="height:30px; width:30px; text-align:center;"
| 374011
| 374011
| Substitution
| T
| A
|-
| || colspan="6" | Nucleotide substitutions within the coding region of BAP2/YBR068C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 139 is now Valine rather than Glutamic Acid, and residue 203 is now Tryptophan rather than Glycine.
<pre>New 373969 GAAGTCAAGGTCAATCTTGTCGAGGGGATTTAATAGCGTAAAATCACGGTTGTAAACCAT 374028
||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||
Old 373966 GAAGTCAAGGTCAATCTTGTCGAGGGGATTTAATAGCGTAAAATCTCGGTTGTAAACCAT 374025
New 375049 AAGAATATAAATGTCCGGATTTATTTTATCATTCCAAAATTGAATAGTCATAGACGCGGT 375108
||||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||
Old 375046 AAGAATATAAATGTCCGGATTTATTTTATCATTCCCAAATTGAATAGTCATAGACGCGGT 375105
New 375229 ATAGGTTACCGCCATCTCACCTGCAGCTTGGATCATGAAGTACGTCACGAAAGAAACCAA 375288
|||||||||||||||||||||||||||||||||||||||||||||| |||||||||||||
Old 375226 ATAGGTTACCGCCATCTCACCTGCAGCTTGGATCATGAAGTACGTCTCGAAAGAAACCAA 375285</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR097W YBR097W]
| 439496
| 439496
| Substitution
| T
| G
|- style="height:30px; width:30px; text-align:center;"
| 437344
| 437344
| Substitution
| A
| G
|-
| || colspan="6" | Nucleotide change(s) in the coding region of VPS15/YBR097W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 134 is now Alanine rather than Threonine, and residue 851 is now Arginine rather than Isoleucine.
<pre>New 437325 ATTCATTGCTTTCCAGTTGTTAAATGCATTAAAGGACATTCATAATCTGAATATTGTCCA 437384
||||||||||||||||||||||||| ||||||||||||||||||||||||||||||||||
Old 437319 ATTCATTGCTTTCCAGTTGTTAAATACATTAAAGGACATTCATAATCTGAATATTGTCCA 437378
New 439485 CTTAACTGCTGAAGACAGAAATTGGATTGATAAGTTCCACATTATTGGGCTAACAGAAAA 439544
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 439479 CTTAACTGCTGAAGACATAAATTGGATTGATAAGTTCCACATTATTGGGCTAACAGAAAA 439538</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR045C YBR045C]
| 328382
| 328382
| Insertion
| || T
|-
| || colspan="6" | A single nucleotide was inserted within ORF GIP1/YBR045C, altering its coding sequence. The start, stop, and majority of the reading frame remain the same, but the C-terminus has changed and the annotated protein is now 66 amino acids longer.
<pre>New 328369 CTCAGTCTATAATTTTCTGCTTCATTTCTCTGCCTTTTATACTCTGTATATTGAAAATAA 328428
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Old 328368 CTCAGTCTATAATTT-CTGCTTCATTTCTCTGCCTTTTATACTCTGTATATTGAAAATAA 328426</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR044C YBR044C]
| 324366
| 324366
| Insertion
|
| T
|-
| || colspan="6" | One nucleotide was inserted within ORF TCM62/YBR044C, very near its 3' end, altering its coding sequence. The start, stop, and majority of reading frame remain the same, but the C-terminus is different and the annotated protein sequence is now one amino acid shorter.
<pre>New 324349 TGTGCCGTTCAGGCTTTTTGTATACACATGTGATAATTGTATTACAGCTTGTAAGTAATT 324408
|||||||||||||||||| |||||||||||||||||||||||||||||||||||||||||
Old 324349 TGTGCCGTTCAGGCTTTT-GTATACACATGTGATAATTGTATTACAGCTTGTAAGTAATT 324407</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR007C YBR007C]
| 250403
| 250403
| Substitution
| C
| G
|- style="height:30px; width:30px; text-align:center;"
| 250039
| 250039
| Substitution
| T
| G
|-
| || colspan="6" | Two nucleotide substitutions within the coding region of DSF2/YBR007C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 205 is now Serine rather than Arginine, and residue 327 is now Proline rather than Threonine.
<pre>New 250012 AGACCGTTTAGGAGATGGTTTGATGGGTGTTGTATCACTCTTAGTTAACTTGAGTTTGGA 250071
|||||||||||||||||||||||||| |||||||||||||||||||||||||||||||||
Old 250013 AGACCGTTTAGGAGATGGTTTGATGGTTGTTGTATCACTCTTAGTTAACTTGAGTTTGGA 250072
New 250372 CCTATATTTCTCGAAGTTGAAAGGATTAGGGCTATTTGTGCTTCTATTGCCATTTTCAAG 250431
|||||||||||||||||||||||||||||| |||||||||||||||||||||||||||||
Old 250373 CCTATATTTCTCGAAGTTGAAAGGATTAGGCCTATTTGTGCTTCTATTGCCATTTTCAAG 250432</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBL105C YBL105C]
| 17455
| 17455
| Substitution
| A
| C
|- style="height:30px; width:30px; text-align:center;"
| 15835
| 15835
| Substitution
| T
| C
|- style="height:30px; width:30px; text-align:center;"
| 15332
| 15332
| Substitution
| G
| C
|-
| || colspan="6" | The substitution of three nucleotides within the coding region of PKC1/YBL105C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 81 is now Cysteine rather than Phenylalanine, residue 621 is now Arginine rather than Lysine, and residue 789 is now Alanine rather than Proline.
<pre>New 15301 TGCGGAGATTGTTGATCAGTGGTTCTGGAGGCATGAGTACTTGTAGGAGCCAAGGACACT 15360
||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||||
Old 15301 TGCGGAGATTGTTGATCAGTGGTTCTGGAGGGATGAGTACTTGTAGGAGCCAAGGACACT 15360
New 15791 TAAATTTATTTAGTTTCTCACGCCCGTGCGTTTGTAGTGAAATTCTTTTATCAATAATAG 15850
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 15791 TAAATTTATTTAGTTTCTCACGCCCGTGCGTTTGTAGTGAAATTTTTTTATCAATAATAG 15840
New 17411 CATTTGGCGATTTGGTAGAAAGAAACCCGTATTCCTTCGAATTGCATCGCTCATTATCTT 17470
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 17411 CATTTGGCGATTTGGTAGAAAGAAACCCGTATTCCTTCGAATTGAATCGCTCATTATCTT 17470</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL057C YBL057C]
| 113437
| 113437
| Deletion
| G
|
|-
| || colspan="6" | One nucleotide was deleted within ORF PTH2/YBL057C, near its 5' end, altering its coding sequence. The stop and reading frame remain the same, but the start has been moved 18 nucleotides downstream and the annotated protein sequence is now six amino acids shorter.
<pre>New 113393 ATGGTGTAATTCGAAGAAACTGTCATCTTTTCCATTAAAAAG-ACGTTATCATGTTACTC 113451
|||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 113395 ATGGTGTAATTCGAAGAAACTGTCATCTTTTCCATTAAAAAGGACGTTATCATGTTACTC 113454</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBL068W YBL068W]
| 92918
| 92920
| Deletion
| CCG
|
|- style="height:30px; width:30px; text-align:center;"
| 92916
| 92916
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 92679
| 92679
| Substitution
| C
| A
|-
| || colspan="6" | Two nucleotide substitutions and one trinucleotide deletion were made within the ORF PRS4/YBL068W, altering its coding sequence. The start, stop, and reading frame remain the same, but the annotated protein is now one amino acid shorter.
<pre>New 92637 TTAATGATTTCTTGATGGAATTATTAATTTTAATTCATGCTTGCAAAATTGCATCTGCAA 92696
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 92635 TTAATGATTTCTTGATGGAATTATTAATTTTAATTCATGCTTGCCAAATTGCATCTGCAA 92694
New 92877 ACAACCTATATGCAGAACCAAGTGTTTTAAATTATATTAGAAC---GAAAACAGATTTCG 92933
||||||||||||||||||||||||||||||||||||||||| | ||||||||||||||
Old 92875 ACAACCTATATGCAGAACCAAGTGTTTTAAATTATATTAGAGCCCGGAAAACAGATTTCG 92934</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR078W YBR078W]
| 394727
| 394727
| Insertion
|
| C
|-
| || colspan="6" | One nucleotide was inserted within ORF ECM33/YBR078W, very near its 3' end, altering its coding sequence. The start, stop, and vast majority of reading frame remain the same, but the C-terminus is different and the annotated protein sequence is now 39 amino acids shorter.
<pre>New 394715 TGCTGCTGTTGGCGTTGCCTTACTATAAGATTAAAGCAACAATTTGTGTTTCTATTATTA 394774
|||||||||||||||||| |||||||||||||||||||||||||||||||||||||||||
Old 394710 TGCTGCTGTTGGCGTTGC-TTACTATAAGATTAAAGCAACAATTTGTGTTTCTATTATTA 394768</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR076W YBR076W]
| 391277
| 391277
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 390442
| 390442
| Deletion
| G
|
|-
| || colspan="6" | A single G nucleotide was deleted near the 3' end, and a single A nucleotide was inserted near the 5' end of ORF ECM8/YBR076W, altering its coding sequence. The ORF was extended 49 amino acids at the N-terminus and shortened 34 amino acids at the C-terminus, resulting in a protein that is 15 amino acids larger. Although this protein is altered at both ends, the central portion of the protein remains the same.
<pre>New 390408 AAACCATCAAGAACAAAATATTCCCACAAAGGAAAATATT-CAACGATAGCGAAAATTTT 390466
|||||||||||||||||||||||||||||||||||||||| |||||||||||||||||||
Old 390402 AAACCATCAAGAACAAAATATTCCCACAAAGGAAAATATTGCAACGATAGCGAAAATTTT 390461
New 391247 CGAACGAAATGTTTATATGTCCAAGTTATAACAAAAAGCAATTGATTGTGTACGCAAGAT 391306
|||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
Old 391242 CGAACGAAATGTTTATATGTCCAAGTTATAACAAAA-GCAATTGATTGTGTACGCAAGAT 391300</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR137W YBR137W]
| 513365
| 513365
| Substitution
| A
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of YBR137W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 110 is now Glycine rather than Serine.
<pre>New 513345 CAAGTTTCTATATGGGCTGCAAGAAAGGTGACAAAACACCGGAGGAAAAGTTTTTTGTGG 513404
|||||||||||||||||||||||||| |||||||||||||||||||||||||||||||||
Old 513339 CAAGTTTCTATATGGGCTGCAAGAAAAGTGACAAAACACCGGAGGAAAAGTTTTTTGTGG 513398</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR121C YBR121C]
| 481671
| 481675
| Substitution
| TGATG
| GTAGT
|-
| || colspan="6" | Nucleotide substitutions within the coding region of GRS1/YBR121C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 563-564 are now TT rather than HH.
<pre>New 481665 TTGGCGACTTCAGTAGTAACAGGAACTAAATCTTTGTGGTTAGATAAAGGAACTAAAAGA 481724
|||||||||||| | |||||||||||||||||||||||||||||||||||||||||||
Old 481659 TTGGCGACTTCATGATGAACAGGAACTAAATCTTTGTGGTTAGATAAAGGAACTAAAAGA 481718</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR108W YBR108W]
| 456359
| 456359
| Substitution
| C
| T
|-
| || colspan="6" | A single nucleotide substitution within the coding region of AIM3/YBR108W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 515 is now Valine rather than Alanine.
<pre>New 456345 AGGACATTATGATGTAGATGTCAACATCATGCCACCTCCAAAACCTTTCAGACATGGACT 456404
|||||||||||||||||||| |||||||||||||||||||||||||||||||||||||||
Old 456339 AGGACATTATGATGTAGATGCCAACATCATGCCACCTCCAAAACCTTTCAGACATGGACT 456398</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR295W YBR295W]
| 793986
| 793987
| Substitution
| AC
| CA
|-
| || colspan="6" | Nucleotide substitutions within the coding region of PCA1/YBR295W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 382 is now Histidine rather than Threonine.
<pre>New 793961 GGATTGTGCTGTTACCTCAACTATTTCTGGACACTCTTCGAGTGAAATTTCAAGAATCGT 794020
||||||||||||||||||||||||||||||| |||||||||||||||||||||||||||
Old 793955 GGATTGTGCTGTTACCTCAACTATTTCTGGAACCTCTTCGAGTGAAATTTCAAGAATCGT 794014</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR289W YBR289W]
| 781354
| 781354
| Substitution
| G
| C
|- style="height:30px; width:30px; text-align:center;"
| 780541
| 780541
| Substitution
| C
| A
|-
| || colspan="6" | Two nucleotide substitutions within the coding region of SNF5/YBR289W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 564 is now Aspartic Acid rather than Glutamic Acid.
<pre>New 780521 ACAACCTCCCACCAATGTTCAGCCAACTATTGGCCAACTTCCTCAACTTCCAAAATTAAA 780580
|||||||||||||||||||||||| |||||||||||||||||||||||||||||||||||
Old 780517 ACAACCTCCCACCAATGTTCAGCCCACTATTGGCCAACTTCCTCAACTTCCAAAATTAAA 780576
New 781311 GATATTGTCGTGGGACAAAACCAGTTAATCGATCAATTTGAGTGGGACATCTCTAATAGT 781370
||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
Old 781307 GATATTGTCGTGGGACAAAACCAGTTAATCGATCAATTTGAGTGGGAGATCTCTAATAGT 781366</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR288C YBR288C]
| 779354
| 779356
| Substitution
| TAC
| ACT
|-
| || colspan="6" | Nucleotide substitutions within the coding region of APM3/YBR288C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 35-36 are now QS rather than RT.
<pre>New 779321 TCACTACTGCTATCTTCGAGCAATTGAGGACATGTGGACTGAACGCGGGTCCACAGGTGC 779380
||||||||||||||||||||||||||||||||||||| ||||||||||||||||||||
Old 779317 TCACTACTGCTATCTTCGAGCAATTGAGGACATGTGGTACGAACGCGGGTCCACAGGTGC 779376</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBL099W YBL099W]
| 38210
| 38210
| Substitution
| A
| T
|- style="height:30px; width:30px; text-align:center;"
| 38067
| 38067
| Substitution
| C
| T
|-
| || colspan="6" | The substitution of 2 nucleotides within the coding region of ATP1/YBL099W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 340 is now Serine rather than Proline.
<pre>New 38039 AGCCTACCCTGGTGATGTCTTTTACTTGCATTCAAGATTGCTAGAAAGAGCCGCTAAGCT 38098
||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||||
Old 38036 AGCCTACCCTGGTGATGTCTTTTACTTGCATCCAAGATTGCTAGAAAGAGCCGCTAAGCT 38095
New 38169 GCTTATATTCCAACCAATGTTATTTCCATTACCGATGGTCAAATTTTCTTGGAAGCTGAA 38228
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 38166 GCTTATATTCCAACCAATGTTATTTCCATTACCGATGGTCAAATATTCTTGGAAGCTGAA 38225</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL097W YBL097W]
| 42377
| 42377
| Substitution
| C
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of BRN1/YBL097W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 517 is now Glycine rather than Alanine.
<pre>New 42359 CAAGATTGTTCATTAAACCGGGGCAGAAAATGAGTCTGTTCAGTCATAGGAAGCATACCA 42418
||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||
Old 42356 CAAGATTGTTCATTAAACCGGCGCAGAAAATGAGTCTGTTCAGTCATAGGAAGCATACCA 42415</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL091C YBL091C]
| 48369
| 48369
| Substitution
| A
| T
|-
| || colspan="6" | A single nucleotide substitution within the coding region of MAP2/YBL091C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 86 is now Aspartic Acid rather than Valine.
<pre>New 48359 ACGTGATTCTTCATCCGTGGTTCTTTGCAGATTGAAATCTTGATGATAGTCCATCCACGC 48418
||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||
Old 48356 ACGTGATTCTTCAACCGTGGTTCTTTGCAGATTGAAATCTTGATGATAGTCCATCCACGC 48415</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL088C YBL088C]
| 55145
| 55145
| Substitution
| A
| C
|-
| || colspan="6" | A single nucleotide substitution within the coding region of TEL1/YBL088C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 1412 is now Cysteine rather than Phenylalanine.
<pre>New 55139 GCATCAAGGCAGTATTTCCAAGTTTTTATTTTGATGAGATCCCGATGCTCTAAAAGCTTT 55198
||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||||
Old 55136 GCATCAAGGAAGTATTTCCAAGTTTTTATTTTGATGAGATCCCGATGCTCTAAAAGCTTT 55195</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL084C YBL084C]
| 68154
| 68155
| Substitution
| TG
| GA
|-
| || colspan="6" | The substitution of two nucleotides within the coding region of CDC27/YBL084C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 430 is now Serine rather than Glutamine.
<pre>New 68108 CGACCTTAATATTAAAGCGAAATTATACATGATTTCAGGCAGCGTAATTGAATAATCACT 68167
||||||||||||||||||||||||||||||||||||||||||||||||| |||||||||
Old 68105 CGACCTTAATATTAAAGCGAAATTATACATGATTTCAGGCAGCGTAATTTGATAATCACT 68164</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR275C YBR275C]
| 754908
| 754908
| Substitution
| T
| C
|-
| || colspan="6" | A single nucleotide substitution within the coding region of RIF1/YBR275C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 732 is now Alanine rather than Threonine.
<pre>New 754902 TACTTCAACAGCCTGGAACACAACTTTCATGATTTTATCGTATTCACGCTTGATGATCTG 754961
||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||
Old 754897 TACTTCAACAGTCTGGAACACAACTTTCATGATTTTATCGTATTCACGCTTGATGATCTG 754956</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR270C YBR270C]
| 743936
| 743938
| Substitution
| GCC
| CCG
|-
| || colspan="6" | Nucleotide substitutions within the coding region of BIT2/YBR270C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 152-153 are now SG rather than RA.
<pre>New 743922 AGTGCCGTAGTTTTTTGACCCGCTCCTGCTTCGATTTCTCATATTATCTTTTGAATTGGT 743981
||||||||||||||||||| | ||||||||||||||||||||||||||||||||||||||
Old 743917 AGTGCCGTAGTTTTTTGACGCCCTCCTGCTTCGATTTCTCATATTATCTTTTGAATTGGT 743976</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR266C YBR266C], [https://www.yeastgenome.org/locus/YBR267W YBR267W]
| 740291
| 740292
| Substitution
| CG
| GC
|-
| || colspan="6" | Nucleotide substitutions within the coding regions of overlapping genes REI1/YBR267W and SLM6/YBR266C resulted in altered sequences for both proteins. The start, stop, and reading frames of both proteins remain the same, but protein residues 152-153 of REI1/YBR267W are now KL rather than NV, and protein residue 31 of SLM6/YBR266C is now Serine rather than Threonine.
<pre>New 740262 AGGAAGAAATGGCGGAAAGAGTAATGCAAGAAAAGCTACGCAACAGAGTCGATATTCCAC 740321
|||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||
Old 740257 AGGAAGAAATGGCGGAAAGAGTAATGCAAGAAAACGTACGCAACAGAGTCGATATTCCAC 740316</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR265W YBR265W]
| 739341
| 739341
| Substitution
| A
| T
|-
| || colspan="6" | A single nucleotide substitution within the coding region of TSC10/YBR265W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 255 is now Aspartic Acid rather than Glutamic Acid.
<pre>New 739302 CAAGCATGTGATATCATTGCCAAGTCGCTGGCCAGAGGTGATGATGACGTTTTTACAGAT 739361
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 739297 CAAGCATGTGATATCATTGCCAAGTCGCTGGCCAGAGGTGATGAAGACGTTTTTACAGAT 739356</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR094W YBR094W]
| 433377
| 433378
| Substitution
| CG
| GC
|- style="height:30px; width:30px; text-align:center;"
| 432380
| 432380
| Substitution
| T
| C
|-
| || colspan="6" | Nucleotide changes within the coding region of PBY1/YBR094W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 450 is now Alanine rather than Arginine.
<pre>New 432345 GAGTGGATATTAATCGATGGAACTCCAGCATCGTGCGCAAACATCGGGCTGCACCTATTG 432404
||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||||
Old 432339 GAGTGGATATTAATCGATGGAACTCCAGCATCGTGCGCAAATATCGGGCTGCACCTATTG 432398
New 433365 ACTATTGATTTAGATTATGCTGAATTTCTAGACGACGCATTAGATGAAAATTGGGAATTA 433424
|||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||
Old 433359 ACTATTGATTTAGATTATCGTGAATTTCTAGACGACGCATTAGATGAAAATTGGGAATTA 433418</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR089C-A YBR089C-A]
| 426394
| 426396
| Substitution
| CCG
| GCC
|-
| || colspan="6" | Nucleotide substitutions within the coding region of NHP6B/YBR089C-A resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 30 is now Glycine rather than Arginine.
<pre>New 426355 GACAATGTCTCTGTTTTCATTAGCAAAGAACATATAAGCTGACAAGCCCCTCTTAGGGGC 426414
||||||||||||||||||||||||||||||||||||||||||||| | ||||||||||||
Old 426349 GACAATGTCTCTGTTTTCATTAGCAAAGAACATATAAGCTGACAACCGCCTCTTAGGGGC 426408</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBL056W YBL056W]
| 114870
| 114870
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 114868
| 114868
| Substitution
| G
| A
|-
| || colspan="6" | Two nucleotide substitutions within the coding region of PTC3/YBL056W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 369 is now Glycine rather than Aspartic Acid.
<pre>New 114832 CGACATGGAAATTGATGATCTTGATACCGAATTAGGCAGCAGTGCTACTCCCTCAAAGTT 114891
||||||||||||||||||||||||||||||||| | ||||||||||||||||||||||||
Old 114835 CGACATGGAAATTGATGATCTTGATACCGAATTGGACAGCAGTGCTACTCCCTCAAAGTT 114894</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="10"| 2011-02-03
| rowspan="10"| [https://www.yeastgenome.org/locus/YBR207W YBR207W]
| 636336
| 636336
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 636319
| 636322
| Substitution
| GCTT
| ACTG
|- style="height:30px; width:30px; text-align:center;"
| 636306
| 636309
| Substitution
| AATA
| TATG
|- style="height:30px; width:30px; text-align:center;"
| 636141
| 636141
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 635890
| 635890
| Deletion
| A
|
|- style="height:30px; width:30px; text-align:center;"
| 635882
| 635882
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 635247
| 635247
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 635192
| 635192
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 636342
| 636342
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 635822
| 635822
| Substitution
| C
| G
|-
| || colspan="6" | Nucleotide changes within the coding region of FTH1/YBR207W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 18 is now Glu rather than Lys, residue 36 is now Gly rather than Asp, residue 228 is now Glu rather than Gln, residues 249-250 are now VF rather than YS, residue 334 is now Gly rather than Glu, residues 389-390 are now IC rather than KY, and residues 399-401 are now EKY rather than GKC.
<pre>New 635196 GGAATCCTTAGAAATTGTTGTCATTGTTTCTATCCTGTTGACGATCGTCAAACAAGGTCT 635255
| |||||||||||||||||||||||||||||||||||||||||||||||||||||| |||
Old 635191 GAAATCCTTAGAAATTGTTGTCATTGTTTCTATCCTGTTGACGATCGTCAAACAAGATCT 635250
New 635803 ACCCAAAAAGGTGTGAAATTCAGTGAAAAGTACTCCTTCTTCATATTACCATTTATAACG 635862
|||||||||||||||||||||||| |||||||||||||||||||||||||||||||||||
Old 635798 ACCCAAAAAGGTGTGAAATTCAGTCAAAAGTACTCCTTCTTCATATTACCATTTATAACG 635857
New 635863 ACTTTGAGAGAAGGGTTAGAAGCTGTTGTATTC-ATTGGAGGTATCGGTATTGACCAACC 635921
||||||||||||||||||||||||| ||||||| ||||||||||||||||||||||||||
Old 635858 ACTTTGAGAGAAGGGTTAGAAGCTG-TGTATTCAATTGGAGGTATCGGTATTGACCAACC 635916
New 636102 AGACTACGTCAACAAATGTAACGGTCAAGACATGAGTGAAGTAGGAAATGGACCCGGTTC 636161
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 636097 AGACTACGTCAACAAATGTAACGGTCAAGACATGAGTGAAGTAGAAAATGGACCCGGTTC 636156
New 636292 GCCTACTGGTTGGTATTAATATGCGCTTTGAAACTGCTAATGATAGAAGAAAAATACGGA 636351
||||||||||||||||||| || ||||||||| || ||||||||||||| ||||| ||||
Old 636287 GCCTACTGGTTGGTATTAAAATACGCTTTGAAGCTTCTAATGATAGAAGGAAAATGCGGA 636346</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL014C YBL014C]
| 201635
| 201635
| Substitution
| G
| C
|-
| || colspan="6" | A single nucleotide substitution within the coding region of RRN6/YBL014C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 39 is now Lysine rather than Asparagine.
<pre>New 201592 CCTCGGCCAATGTATCATCTACTGGTCTTAGCCATTGTGGCTTTTCTTGCTTCTTCGTAG 201651
|||||||||||||||||||||||||||||||||||||||| |||||||||||||||||||
Old 201595 CCTCGGCCAATGTATCATCTACTGGTCTTAGCCATTGTGGGTTTTCTTGCTTCTTCGTAG 201654</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL008W YBL008W]
| 210433
| 210433
| Substitution
| A
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of HIR1/YBL008W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 260 is now Valine rather than Methionine.
<pre>New 210412 AATGGGCCCGTAAGTTCTGTGGCAATTGTAAATAGAGGAACTTGGGATACAAATGTTAGT 210471
|||||||||||||||||| |||||||||||||||||||||||||||||||||||||||||
Old 210415 AATGGGCCCGTAAGTTCTATGGCAATTGTAAATAGAGGAACTTGGGATACAAATGTTAGT 210474</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR043C YBR043C]
| 323835
| 323836
| Substitution
| CG
| GC
|-
| || colspan="6" | Nucleotide substitutions within the coding region of QDR3/YBR043C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 37 is now Serine rather than Threonine.
<pre>Query 323809 CTATAATCGTTGTGCTCGCTGTGCGGGCTGCCGCTGCTTTCATCGCAGTGCATCATAACA 323868
|||||||||||||||||||||||||| ||||||||||||||||||||||||||||||||
Sbjct 323809 CTATAATCGTTGTGCTCGCTGTGCGGCGTGCCGCTGCTTTCATCGCAGTGCATCATAACA 323868</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR141C YBR141C]
| 527099
| 527099
| Substitution
| A
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of YBR141C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 312 is now Proline rather than Serine.
<pre>New 527085 AAAGCTACTCGGCTGCGGTGGAACTACCTGCAATTGATACAAACAATAGTACAACTTATT 527144
|||||||||||||||||||| |||||||||||||||||||||||||||||||||||||||
Old 527079 AAAGCTACTCGGCTGCGGTGAAACTACCTGCAATTGATACAAACAATAGTACAACTTATT 527138</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR138C YBR138C]
| 514965
| 514966
| Substitution
| AC
| CA
|-
| || colspan="6" | Nucleotide substitutions within the coding region of YBR138C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 122 is now Leucine rather than Cysteine.
<pre>New 514955 TAGGCTTGGCACCTATCAATTGTGAGCGACGCTTTCTTACATTCAATAACTGTTGGTTCT 515014
|||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 514949 TAGGCTTGGCACCTATACATTGTGAGCGACGCTTTCTTACATTCAATAACTGTTGGTTCT 515008</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR004C YBR004C]
| 245111
| 245111
| Substitution
| T
| A
|-
| || colspan="6" | A single nucleotide substitution within the coding region of GPI18/YBR004C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 187 is now Serine rather than Threonine.
<pre>New 245092 TACGGGCACGGAAATGGAGCATTCACGACTCCAAATACCAACAAATGCAAAAAAAAAAGA 245151
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 245094 TACGGGCACGGAAATGGTGCATTCACGACTCCAAATACCAACAAATGCAAAAAAAAAAGA 245153</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="8"| 2011-02-03
| rowspan="8"| [https://www.yeastgenome.org/locus/YBL106C YBL106C]
| 13553
| 13553
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 13492
| 13492
| Substitution
| A
| T
|- style="height:30px; width:30px; text-align:center;"
| 13477
| 13477
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 13102
| 13102
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 11379
| 11379
| Substitution
| A
| C
|- style="height:30px; width:30px; text-align:center;"
| 11345
| 11345
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 11308
| 11309
| Substitution
| AA
| TT
|- style="height:30px; width:30px; text-align:center;"
| 11053
| 11053
| Substitution
| T
| C
|-
| || colspan="6" | Several nucleotide substitutions within the coding region of SRO77/YBL106C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 130 is now Isoleucine rather than Phenylalanine, residue 135 is now Serine rather than Proline, residue 260 is now Serine rather than Alanine, residue 834 is now Glycine rather than Valine, residue 858 is now Threonine rather than Serine, and 943 is now Glutamic Acid rather than Lysine.
<pre>New 11041 ACCTGTGATCTTCCGTACCGGGAGGTAACTTTCTGGCTGCATTACTACTACTGGAAGATA 11100
|||||||||||| |||||||||||||||||||||||||||||||||||||||||||||||
Old 11041 ACCTGTGATCTTTCGTACCGGGAGGTAACTTTCTGGCTGCATTACTACTACTGGAAGATA 11100
New 11281 GTTGTGATATGTCAGCAGTATGATTCGTTCCGGTGGCACTTTCATTAAGTACTGAAATCA 11340
||||||||||||||||||||||||||| |||||||||||||||||||||||||||||||
Old 11281 GTTGTGATATGTCAGCAGTATGATTCGAACCGGTGGCACTTTCATTAAGTACTGAAATCA 11340
New 11341 AAGAGGCTTGGAATTTCCCTGTGCGAATGACAATGTCACCATTTTCTAATATAGATGAAT 11400
|||| ||||||||||||||||||||||||||||||||| |||||||||||||||||||||
Old 11341 AAGAAGCTTGGAATTTCCCTGTGCGAATGACAATGTCAACATTTTCTAATATAGATGAAT 11400
New 13081 TGACATCCCAAAATACCAAGGAATTATCTTCATGGACAGTTAATATATGTAAGGAATTTG 13140
||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||
Old 13081 TGACATCCCAAAATACCAAGGCATTATCTTCATGGACAGTTAATATATGTAAGGAATTTG 13140
New 13441 ATCCACTCTCGAGGCCAATCAGCATCCAATCCAAGGACGGATCAGTCTCAATACAAGTGA 13500
|||||||||||||||||||||||||||||||||||| |||||||||||||| ||||||||
Old 13441 ATCCACTCTCGAGGCCAATCAGCATCCAATCCAAGGGCGGATCAGTCTCAAAACAAGTGA 13500
New 13501 TGCTGTTTGGACAGAAAACAGTAGTTAGAATCTGTTTCGAGTGTACTGAAAGAACTATTA 13560
|||||||||||||||||||||||||||||||||||||||||||||||||||| |||||||
Old 13501 TGCTGTTTGGACAGAAAACAGTAGTTAGAATCTGTTTCGAGTGTACTGAAAGGACTATTA 13560</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="6"| 2011-02-03
| rowspan="6"| [https://www.yeastgenome.org/locus/YBR203W YBR203W]
| 631936
| 631936
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 631924
| 631924
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 631912
| 631912
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 631907
| 631907
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 631342
| 631353
| Substitution
| GCTGGCGAAACG
| CGTTTCGCCAGC
|- style="height:30px; width:30px; text-align:center;"
| 631940
| 631940
| Substitution
| C
| A
|-
| || colspan="6" | Nucleotide changes within the coding region of COS111/YBR203W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 727-731 are now TFRQH rather than SWRND, residue 917 is now Asparagine rather than Serine, and residue 921 is now Glutamic Acid rather than Glycine.
<pre>New 631303 TGTGTGGTGCAGGCAATATATGGTAAAGTATTTTGTAATGAGGACGTTTCGCCAGCATTT 631362
|||||||||||||||||||||||||||||||||||||||||||| | || | ||||
Old 631298 TGTGTGGTGCAGGCAATATATGGTAAAGTATTTTGTAATGAGGAGCTGGCGAAACGATTT 631357
New 631903 TGTTGGCGAAAATAACTACTATGCTGAAAGCATCATATAACGACTGCTCTCTTTTAACAG 631962
||||||||| |||| ||||||||||| ||||||||||| ||| |||||||||||||||||
Old 631898 TGTTGGCGAGAATAGCTACTATGCTGGAAGCATCATATGACGCCTGCTCTCTTTTAACAG 631957</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR285W YBR285W]
| 774080
| 774080
| Substitution
| C
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of YBR285W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 55 is now Aspartic Acid rather than Histidine.
<pre>New 774041 CTTAGAAAGCCCCACTGACGATAGCATGGAGGCGGACATTTCAGATAGAGAAATGGCTAC 774100
||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||
Old 774037 CTTAGAAAGCCCCACTGACGATAGCATGGAGGCGGACATTTCACATAGAGAAATGGCTAC 774096</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR204C YBR204C]
| 633189
| 633189
| Substitution
| T
| A
|-
| || colspan="6" | A single nucleotide substitution within the coding region of YBR204C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 63 is now Valine rather than Glutamic Acid.
<pre>New 633163 CCTTATTCTTGAATTTCGATCCGATAGTTGTACATTAAAAAACTCCTCATGTTCTGCGAT 633222
||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||||
Old 633158 CCTTATTCTTGAATTTCGATCCGATAGTTGTTCATTAAAAAACTCCTCATGTTCTGCGAT 633217</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBR202W YBR202W]
| 627486
| 627487
| Substitution
| AT
| TA
|- style="height:30px; width:30px; text-align:center;"
| 627433
| 627439
| Substitution
| ATCCGGG
| CTTTGAA
|- style="height:30px; width:30px; text-align:center;"
| 627421
| 627421
| Substitution
| T
| G
|-
| || colspan="6" | Nucleotide changes within the coding region of MCM7/YBR202W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residues 552-558 is now GINTTLN rather than VINTNPG, and residue 574 is now Tyrosine rather than Isoleucine.
<pre>New 627403 AACAATTTCGATATCCAAGGCGGGTATCAATACAACTTTGAACGCCAGAACCTCAATCTT 627462
||||||||||||||||||||||| ||||||||||| | | ||||||||||||||||||
Old 627398 AACAATTTCGATATCCAAGGCGGTTATCAATACAAATCCGGGCGCCAGAACCTCAATCTT 627457
New 627463 AGCGGCAGCAAATCCGTTGTATGGTAGATATAATCCTAGATTATCACCTCTGGACAATAT 627522
|||||||||||||||||||||||||||| ||||||||||||||||||||||||||||||
Old 627458 AGCGGCAGCAAATCCGTTGTATGGTAGAATTAATCCTAGATTATCACCTCTGGACAATAT 627517</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL080C YBL080C]
| 73450
| 73450
| Substitution
| C
| G
|-
| || colspan="6" | A single nucleotide substitution within the coding region of PET112/YBL080C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 415 is now Proline rather than Alanine.
<pre>New 73438 CGAAAACCGGAGGAGGCAAAATTTCTTTTGCTTTGGCCAATGGAATTTGTAGCTTGTTCA 73497
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Old 73435 CGAAAACCGGAGGAGCCAAAATTTCTTTTGCTTTGGCCAATGGAATTTGTAGCTTGTTCA 73494</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL067C YBL067C]
| 95345
| 95345
| Substitution
| G
| T
|-
| || colspan="6" | A single nucleotide substitution within the coding region of UBP13/YBL067C resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 180 is now Glutamine rather than Histidine.
<pre>New 95333 TCTTTCTTGGTTGATCAGATTCTCTTGATTTTTTTGGAAATTGCAATATATTTTCACGTA 95392
|||||||||| |||||||||||||||||||||||||||||||||||||||||||||||||
Old 95335 TCTTTCTTGGGTGATCAGATTCTCTTGATTTTTTTGGAAATTGCAATATATTTTCACGTA 95394</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR074W YBR074W]
| 388774
| 388775
| Substitution
| TT
| AA
|-
| || colspan="6" | Nucleotide substitutions within the coding region of YBR074W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 832 is now Asparagine rather than Phenylalanine.
<pre>New 388738 ACGAACCAATAGTTGCAGAGTTACTTTTGGAGGTGAAGGAGAACAGGGCTTGCACTTTAA 388797
||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 388733 ACGAACCAATAGTTGCAGAGTTACTTTTGGAGGTGAAGGAGTTCAGGGCTTGCACTTTAA 388792</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR073W YBR073W]
| 385360
| 385361
| Substitution
| CG
| GC
|-
| || colspan="6" | Nucleotide substitutions within the coding region of RDH54/YBR073W resulted in an altered protein sequence. The start, stop, and reading frame remain the same, but protein residue 752 is now Alanine rather than Arginine.
<pre>New 385318 TCTTGTTGAGTGCAAAATCGGGAGGTGTAGGATTGAATCTAGTCGGTGCTTCGCGACTTA 385377
||||||||||||||||||||||||||||||||||||||||||||||| |||||||||||
Old 385313 TCTTGTTGAGTGCAAAATCGGGAGGTGTAGGATTGAATCTAGTCGGTCGTTCGCGACTTA 385367</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR152W YBR152W], [https://www.yeastgenome.org/locus/YBR153W YBR153W]
| 547442
| 547442
| Substitution
| A
| T
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs SPP381/YBR152W and RIB7/YBR153W.
<pre>New 547425 GCTTCTTTGTATTACTATCAACATTTTTAGAAGATATGTCTTTGACACCACTGTGTGAAG 547484
||||||||||||||||||||||| ||||||||||||||||||||||||||||||||||||
Old 547419 GCTTCTTTGTATTACTATCAACAATTTTAGAAGATATGTCTTTGACACCACTGTGTGAAG 547478</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBLCtau1 YBLCtau1], [https://www.yeastgenome.org/locus/tF(GAA)B tF(GAA)B]
| 36312
| 36312
| Substitution
| T
| A
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between Ty4 LTR YBLCtau1 and tRNA-Phe tF(GAA)B.
<pre>New 36299 TGTGCTTCAGTATTACATTTTTTGCCTTCAACGCCTTGATTGTTCTATTTTTGCTAATAA 36358
|||||||||||||||| |||||||||||||||||||||||||||||||||||||||||||
Old 36296 TGTGCTTCAGTATTACTTTTTTTGCCTTCAACGCCTTGATTGTTCTATTTTTGCTAATAA 36355</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL099W YBL099W], [https://www.yeastgenome.org/locus/tF(GAA)B tF(GAA)B]
| 36673
| 36673
| Substitution
| A
| T
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between tRNA-Phe tF(GAA)B and ORF ATP1/YBL099W.
<pre>New 36659 ATTTATTGTAATTATTATACATTGGTCATATCAAATTCACATCAGACTTCAATTTTTCAA 36718
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 36656 ATTTATTGTAATTATTAAACATTGGTCATATCAAATTCACATCAGACTTCAATTTTTCAA 36715</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR006W YBR006W], [https://www.yeastgenome.org/locus/YBR007C YBR007C]
| 248623
| 248623
| Insertion
|
| T
|-
| || colspan="6" | A single nucleotide insertion was made in the intergenic region between ORFs UGA2/YBR006W and DSF2/YBR007C.
<pre>New 248572 GCATGTATAAATACTCTACTCCTCGTATATAGAAAGTTAAGTAAATTTTTTGAAAGAAAA 248631
|||||||||||||||||||||||||||||||||||||||||||||||||| |||||||||
Old 248574 GCATGTATAAATACTCTACTCCTCGTATATAGAAAGTTAAGTAAATTTTT-GAAAGAAAA 248632</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR001C YBR001C], [https://www.yeastgenome.org/locus/YBR002C YBR002C]
| 241396
| 241396
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 241359
| 241359
| Substitution
| G
| A
|-
| || colspan="6" | Two separate single nucleotide substitutions were made in the intergenic region between ORFs NTH2/YBR001C and RER2/YBR002C.
<pre>New 241352 AAAGGAAAAATATAAATAAATAAATAAAATTGAGAAATAAAGATATTTAGTTTTAATGGA 241411
||||| |||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 241354 AAAGGGAAAATATAAATAAATAAATAAAATTGAGAAATAAAGGATATTAGTTTTAATGGA 241413</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL005W YBL005W], [https://www.yeastgenome.org/locus/YBLWdelta8 YBLWdelta8]
| 220413
| 220414
| Substitution
| AG
| GA
|-
| || colspan="6" | A dinucleotide substitution was made in the intergenic region between ORF PDR3/YBL005W and Ty1 LTR YBLWdelta8.
<pre>New 220372 ATGACAATACTTCATATCCCTTCTTATGAAAACGCAAAGAAAATAGGGAAGCAGAGCATA 220431
|||||||||||||||||||||||||||||||||||||| ||||||||||||||||||||
Old 220375 ATGACAATACTTCATATCCCTTCTTATGAAAACGCAAAAGAAATAGGGAAGCAGAGCATA 220434</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBL105C YBL105C], [https://www.yeastgenome.org/locus/YBL106C YBL106C]
| 13982
| 13982
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 13966
| 13966
| Substitution
| C
| A
|-
| || colspan="6" | Two separate single nucleotide substitutions were made in the intergenic region between ORFs SRO77/YBL106C and PKC1/YBL105C.
<pre>New 13941 AGAAATATGTTAGTAGTAATATAATACTGAGCTGTTTCTTAAATGCTTCCTTAATAATGT 14000
||||||||||||||||||||||||| ||||||||||||||| ||||||||||||||||||
Old 13941 AGAAATATGTTAGTAGTAATATAATCCTGAGCTGTTTCTTAGATGCTTCCTTAATAATGT 14000</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="6"| 2011-02-03
| rowspan="6"| [https://www.yeastgenome.org/locus/ARS209 ARS209]
| 254720
| 254720
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 254719
| 254719
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 254616
| 254616
| Substitution
| T
| A
|- style="height:30px; width:30px; text-align:center;"
| 254548
| 254548
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 254532
| 254532
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 254495
| 254495
| Substitution
| G
| T
|-
| || colspan="6" | Several nucleotide changes were made within ARS209.
<pre>New 254452 AAATATCCTTTTTTTTTTCTTTGCATTTGTCTTCTTTCATTTTAAATCTTCATAATCTTC 254511
|||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 254453 AAATATCCTTTTTTTTTTCTTTGCATTTGTCTTCTTTCATTTGAAATCTTCATAATCTTC 254512
New 254512 CGGAAAAACTAGTGATGCGAAATATTGTAGAGAAAAAGCGCAGGGCATTCCTATACTTAG 254571
||||||||||||||||||| |||||||||||||||| |||||||||||||||||||||||
Old 254513 CGGAAAAACTAGTGATGCGCAATATTGTAGAGAAAA-GCGCAGGGCATTCCTATACTTAG 254571
New 254572 TAATCACCATCATAACGTATTTTAAAATGAAGAAGCGAACCTCAAAGAATTTTCTATACA 254631
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 254572 TAATCACCATCATAACGTATTTTAAAATGAAGAAGCGAACCTCATAGAATTTTCTATACA 254631
New 254692 TATATTGCAGAAAATGTGCTAGTAATATTGTTCTCTCTGTTGTCAATGGGCTTACAATTG 254751
|||||||||||||||||||||||||||| | |||||||||||||||||||||||||||||
Old 254692 TATATTGCAGAAAATGTGCTAGTAATAT-G-TCTCTCTGTTGTCAATGGGCTTACAATTG 254749</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR285W YBR285W], [https://www.yeastgenome.org/locus/YBR286W YBR286W]
| 774430
| 774430
| Substitution
| C
| G
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs YBR285W and APE3/YBR286W.
<pre>New 774401 CTTATCGTCAGAAAGAGTGTTCTCTATGTTTTTGTGCTTCCATAAATATATAGTTCAAAA 774460
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||
Old 774397 CTTATCGTCAGAAAGAGTGTTCTCTATGTTTTTCTGCTTCCATAAATATATAGTTCAAAA 774456</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/ARS221 ARS221]
| 631981
| 631981
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 631940
| 631940
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 631936
| 631936
| Substitution
| G
| A
|-
| || colspan="6" | Three single nucleotide substitutions were made within ARS221.
<pre>New 631933 CATCATATAACGACTGCTCTCTTTTAACAGCATACGTTCTGTTAATTTATTTGGCCAAAT 631992
|||||||| ||| |||||||||||||||||||||||||||||||||||||||| ||||||
Old 631928 CATCATATGACGCCTGCTCTCTTTTAACAGCATACGTTCTGTTAATTTATTTGACCAAAT 631987</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/ARS213 ARS213]
| 390033
| 390033
| Insertion
|
| C
|-
| || colspan="6" | A single nucleotide insertion was made within ARS213.
<pre>New 389998 ACTGACACTAAAAAAAGGGTCGTACGTCTTACTGGCAGCGCCGAAAAATGTTTCGAAAAT 390057
||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||||
Old 389993 ACTGACACTAAAAAAAGGGTCGTACGTCTTACTGGCAGCGC-GAAAAATGTTTCGAAAAT 390051</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR201C-A YBR201C-A], [https://www.yeastgenome.org/locus/YBR202W YBR202W]
| 625500
| 625500
| Substitution
| T
| C
|- style="height:30px; width:30px; text-align:center;"
| 625435
| 625435
| Insertion
|
| T
|-
| || colspan="6" | A single nucleotide insertion and a single nucleotide substitution were made in the intergenic region between ORFs YBR201C-A and MCM7/YBR202W.
<pre>New 625423 ATTTTCTCAATAACAGGTCGAGGCCCCTTCTACCCTTGAATGCTACTTATTACTCACTCA 625482
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 625419 ATTTTCTCAATAACAGG-CGAGGCCCCTTCTACCCTTGAATGCTACTTATTACTCACTCA 625477
New 625483 TAATACATTGTATAAGCCTTCGCGTTTTTCACGGCCTCGAAAAAATTTTTCTTAACTAAT 625542
|||||||||||||||||||||| |||||||||||||||||||||||||||||||||||||
Old 625478 TAATACATTGTATAAGCCTTCGTGTTTTTCACGGCCTCGAAAAAATTTTTCTTAACTAAT 625537</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR200W-A YBR200W-A], [https://www.yeastgenome.org/locus/YBR201W YBR201W]
| 623444
| 623444
| Deletion
| C
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORFs YBR200W-A and DER1/YBR201W.
<pre>New 623434 GAAGGTATAACAAAA-CAGATAGACACCTAATAAAGAACAAAATATTCCTATAGTTTTGC 623492
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Old 623429 GAAGGTATAACAAAACCAGATAGACACCTAATAAAGAACAAAATATTCCTATAGTTTTGC 623488</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL001C YBL001C], [https://www.yeastgenome.org/locus/YBL002W YBL002W]
| 237021
| 237021
| Insertion
|
| G
|-
| || colspan="6" | A single nucleotide insertion was made in the intergenic region between ORFs HTB2/YBL002W and ECM15/YBL001C.
<pre>New 236992 AGGGTCTAGTCTATCAGCCTCCGAAGGGAGTTGTATAAATGTATATATATAACTTTATAA 237051
||||||||||||||||||||||||||| ||||||||||||||||||||||||||||||||
Old 236995 AGGGTCTAGTCTATCAGCCTCCGAAGG-AGTTGTATAAATGTATATATATAACTTTATAA 237053</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/ARS208 ARS208], [https://www.yeastgenome.org/locus/CEN2 CEN2]
| 238133
| 238133
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 238116
| 238116
| Substitution
| G
| A
|-
| || colspan="6" | Two separate single nucleotide substitutions were made in the intergenic region between ARS208 and CEN2.
<pre>New 238082 AGTACTTGCTTTCAGCAGAAAATGAAAAAAAGAACGTTCAAACAGACTGAAAATATAGCT 238141
|||||||||||||||||||||||||||||||| |||||||||||||||| ||||||||||
Old 238084 AGTACTTGCTTTCAGCAGAAAATGAAAAAAAGGACGTTCAAACAGACTGGAAATATAGCT 238143</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL079W YBL079W], [https://www.yeastgenome.org/locus/YBL080C YBL080C]
| 75208
| 75208
| Substitution
| A
| G
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs PET112/YBL080C and NUP170/YBL079W.
<pre>New 75178 GGAGAATTACTGGAACCTAGGATCTGACAAGCGGACAAAAAAGCAGAGTGCGTTTATTAC 75237
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||
Old 75175 GGAGAATTACTGGAACCTAGGATCTGACAAGCGAACAAAAAAGCAGAGTGCGTTTATTAC 75234</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL077W YBL077W], [https://www.yeastgenome.org/locus/YBL078C YBL078C]
| 80747
| 80747
| Deletion
| T
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORFs ATG8/YBL078C and YBL077W.
<pre>New 80708 TTCAGACTTAAATGTAGACTTCATGTCTCTAGTAATTATTTT-ATTATGATTTTCTCAAC 80766
|||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 80705 TTCAGACTTAAATGTAGACTTCATGTCTCTAGTAATTATTTTTATTATGATTTTCTCAAC 80764</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL072C YBL072C]
| 89277
| 89277
| Substitution
| G
| T
|-
| || colspan="6" | A single nucleotide substitution was made within the 5' UTR intron of ORF RPS8A/YBL072C.
<pre>New 89267 GGCTTGATTTTTTGGGTACACAAAGGATTCAGTTTAGTGCACTGCTCCTGTCACAATTTA 89326
|||||||||||| |||||||||||||||||||||||||||||||||||||||||||||||
Old 89265 GGCTTGATTTTTGGGGTACACAAAGGATTCAGTTTAGTGCACTGCTCCTGTCACAATTTA 89324</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL067C YBL067C], [https://www.yeastgenome.org/locus/YBL068W YBL068W]
| 93622
| 93622
| Deletion
| C
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORFs PRS4/YBL068W and UBP13/YBL067C.
<pre>New 93594 AAAGGAGACGGTGAACCTTTACCTTCC-TTGATATGCAAATATTTTTCAGCTTTTCCTAA 93652
||||||||||||||||||||||||||| ||||||||||||||||||||||||||||||||
Old 93595 AAAGGAGACGGTGAACCTTTACCTTCCCTTGATATGCAAATATTTTTCAGCTTTTCCTAA 93654</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="4"| 2011-02-03
| rowspan="4"| [https://www.yeastgenome.org/locus/YBR077C YBR077C], [https://www.yeastgenome.org/locus/YBR078W YBR078W]
| 392822
| 392822
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 392568
| 392569
| Substitution
| CG
| GC
|- style="height:30px; width:30px; text-align:center;"
| 392557
| 392558
| Substitution
| CG
| GC
|- style="height:30px; width:30px; text-align:center;"
| 392340
| 392340
| Deletion
| TT
|
|-
| || colspan="6" | Several nucleotide changes were made in the intergenic region between ORFs SLM4/YBR077C and ECM33/YBR078W.
<pre>New 392327 GATAACTGCCTTTTTTTTTT--CTTCTTATCTTCCCTTAATTAATTCATTAGAGTCTTTT 392384
|||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||
Old 392321 GATAACTGCCTTTTTTTTTTTTCTTCTTATCTTCCCTTAATTAATTCATTAGAGTCTTTT 392380
New 392545 CACGACCCGGGTGGCTGCTGCGCCCTCGCGAAAAAGAAATGAAATGGAGTGCAAAAACGG 392604
|||||||||||||||| ||||||||| |||||||||||||||||||||||||||||||
Old 392541 CACGACCCGGGTGGCTCGTGCGCCCTCCGGAAAAAGAAATGAAATGGAGTGCAAAAACGG 392600
New 392805 AATGTCAAACACCTACGACTTTTCGCAATCAACGGACCTCTCTTGCATTTTTGTATTTAA 392864
|||||||||||||||||||||| |||||||||||||||||||||||||||||||||||||
Old 392801 AATGTCAAACACCTACGACTTT-CGCAATCAACGGACCTCTCTTGCATTTTTGTATTTAA 392859</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR072C-A YBR072C-A], [https://www.yeastgenome.org/locus/YBR072W YBR072W]
| 382742
| 382742
| Insertion
|
| G
|- style="height:30px; width:30px; text-align:center;"
| 382729
| 382729
| Insertion
|
| G
|-
| || colspan="6" | Two separate single nucleotide insertions were made in the intergenic region between ORFs HSP26/YBR072W and YBR072C-A.
<pre>New 382719 TTGCTTGCATATGGGCTTGAAACATATGGTCATCACATCTGAGCGATTTTACCTCTTAGA 382778
|||||||||||||| ||||||||||||| |||||||||||||||||||||||||||||||
Old 382716 TTGCTTGCATATGG-CTTGAAACATATG-TCATCACATCTGAGCGATTTTACCTCTTAGA 382773</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR066C YBR066C], [https://www.yeastgenome.org/locus/YBR067C YBR067C]
| 371424
| 371424
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 370774
| 370773
| Substitution
| C
| T
|-
| || colspan="6" | A single nucleotide substitution and a single nucleotide insertion were made in the intergenic region between ORFs NRG2/YBR066C and TIP1/YBR067C.
<pre>New 370729 TTGTTCTTCGAACAGTAGCGAGTGCTCATATGACTTGGTGCCGGAAATTCATTTGAGCTG 370788
||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
Old 370727 TTGTTCTTCGAACAGTAGCGAGTGCTCATATGACTTGGTGCCGGAAACTCATTTGAGCTG 370786
New 371389 AAGGTTATAGTCTCCTTTTTTTCTTGGCTTCGGGAAAAATACGATTTGTTTGTTATTCTA 371448
|||||||||||||||||||||||||||||||||||||| |||||||||||||||||||||
Old 371387 AAGGTTATAGTCTCCTTTTTTTCTTGGCTTCGGGAAAA-TACGATTTGTTTGTTATTCTA 371445</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/ARS230 ARS230], [https://www.yeastgenome.org/locus/YBL100W-C YBL100W-C]
| 28909
| 28909
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 28887
| 28887
| Insertion
|
| AT
|-
| || colspan="6" | A dinucleotide insertion and a mononucleotide insertion were made in the intergenic region between ORF YBL100W-C and ARS230.
<pre>New 28859 ATTACTGTTTCGGGAATATAACGTTTGATATCGCTAGCGCACCCAGATGAGAAATCCGCA 28918
||||||||||||||||||||||||||||| |||||||||||||||||||||| ||||||
Old 28859 ATTACTGTTTCGGGAATATAACGTTTGAT--CGCTAGCGCACCCAGATGAGAA-TCCGCA 28915</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/ARS228 ARS228]
| 792273
| 792273
| Insertion
|
| T
|-
| || colspan="6" | A single nucleotide insertion was made within ARS228.
<pre>New 792231 TTTGTTATGAATCTGAAAAGAAAAATACTATTTTAGCAATACAATGAATTTTAAAAAGTT 792290
|||||||||||||||||||||||||||||||||||||||||||||||| |||||||||||
Old 792226 TTTGTTATGAATCTGAAAAGAAAAATACTATTTTAGCAATACAATGAA-TTTAAAAAGTT 792284</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/ARS225 ARS225], [https://www.yeastgenome.org/locus/YBR275C YBR275C]
| 757291
| 757291
| Deletion
| A
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORF RIF1/YBR275C and ARS225.
<pre>New 757242 ATCTTCTTGCTAACGATGAGTCGCCAATAAATAAAAAATCGACG-CGTCGGTCAATTATA 757310
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 757237 ATCTTCTTGCTAACGATGAGTCGCCAATAAATAAAAAATCGACGACGTCGGTCAATTATA 757306</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/ARS208 ARS208]
| 237892
| 237892
| Substitution
| G
| A
|- style="height:30px; width:30px; text-align:center;"
| 237839
| 237839
| Substitution
| G
| A
|-
| || colspan="6" | Two separate single nucleotide substitutions were made within ARS208.
<pre>New 237832 TTGCGAAAATTATTCTTTAATAGTTTAACTAAAAGTAAAAAGTTAGAAATCATAAATAAA 237891
||||| |||||||||||||||||||||||||||||||||||||||||||||||||||| |
Old 237834 TTGCGGAAATTATTCTTTAATAGTTTAACTAAAAGTAAAAAGTTAGAAATCATAAATAGA 237893</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL103C YBL103C], [https://www.yeastgenome.org/locus/YBL104C YBL104C]
| 21376
| 21376
| Insertion
|
| A
|-
| || colspan="6" | A single nucleotide insertion was made in the intergenic region between ORFs YBL104C and RTG3/YBL103C.
<pre>New 21361 CTTATGCTATCTTGAAATATATCATCGCCGTAAAGTATGATGTGTAGCGCATTAGTCTTC 21420
|||||||||||||||| |||||||||||||||||||||||||||||||||||||||||||
Old 21361 CTTATGCTATCTTGAA-TATATCATCGCCGTAAAGTATGATGTGTAGCGCATTAGTCTTC 21419</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBL102W YBL102W], [https://www.yeastgenome.org/locus/YBL103C YBL103C]
| 28913
| 28913
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 23855
| 23856
| Deletion
| CC
|
|- style="height:30px; width:30px; text-align:center;"
| 23947
| 23947
| Insertion
|
| A
|-
| || colspan="6" | Several sequence changes were made in the intergenic region between ORFs RTG3/YBL103C and SFT2/YBL102W.
<pre>New 23821 GAAGGCTTTTCTAATCACCATGGCTTTATTATTTC--AAAAGTAACTTGCGAAGAGTCAC 23878
||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
Old 23820 GAAGGCTTTTCTAATCACCATGGCTTTATTATTTCCCAAAAGTAACTTGCGAAGAGTCAC 23879
New 23879 ATCCCGCGGAACGGCCCGCAATCGTGACCCGGCAAAAGGCGATTGTAATGAAGAGGGAGT 23938
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||
Old 23880 ATCCCGCGGAACGGCCCGCAATCGTGACCCGGCCAAAGGCGATTGTAATGAAGAGGGAGT 23939
New 23939 ATTGGTCAAGACTTGTACTATACTGAAATAGGAAGAAGATTGAATAAATTTGCATTCTAA 23998
|||||||| |||||||||||||||||||||||||||||||||||||||||||||||||||
Old 23940 ATTGGTCA-GACTTGTACTATACTGAAATAGGAAGAAGATTGAATAAATTTGCATTCTAA 23998</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR125C YBR125C], [https://www.yeastgenome.org/locus/YBR126C YBR126C]
| 488600
| 488601
| Substitution
| TC
| AT
|-
| || colspan="6" | A dinucleotide substitution was made in the intergenic region between ORFs PTC4/YBR125C and TPS1/YBR126C.
<pre>New 488565 CGTTATGCGGTGTGAACAGCGACAATAAAAAAAAATGTGGGATAAATTATGGCTTTTTTT 488624
||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 488559 CGTTATGCGGTGTGAACAGCGACAATAAAAAAAAATGTGGGTCAAATTATGGCTTTTTTT 488618</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR102C YBR102C], [https://www.yeastgenome.org/locus/YBR103W YBR103W]
| 447535
| 447536
| Substitution
| CG
| GC
|-
| || colspan="6" | A dinucleotide substitution was made in the intergenic region between ORFs EXO84/YBR102C and SIF2/YBR103W.
<pre>New 447525 AAAGGTTATGAGATATGCAAGACCATTCGTTTTGATTTGCAATTAGTGAGAACAATTTAA 447584
|||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 447519 AAAGGTTATGAGATATCGAAGACCATTCGTTTTGATTTGCAATTAGTGAGAACAATTTAA 447578</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 2011-02-03
| rowspan="3"| [https://www.yeastgenome.org/locus/YBR013C YBR013C], [https://www.yeastgenome.org/locus/YBRCdelta14 YBRCdelta14]
| 265922
| 265922
| Deletion
| C
|
|- style="height:30px; width:30px; text-align:center;"
| 265905
| 265905
| Substitution
| T
| G
|- style="height:30px; width:30px; text-align:center;"
| 265902
| 265902
| Deletion
| C
|
|-
| || colspan="6" | Several nucleotide changes were made within the intergenic region between ORF YBR013C and Ty1 LTR YBRCdelta14.
<pre>New 265852 GATACATATCCTGAATAAGGGATATATCATTATGAGGTTAAGTGGCCTAAAA-ACGCAAT 265910
|||||||||||||||||||||||||||||||||||||||||||||||||||| || ||||
Old 265850 GATACATATCCTGAATAAGGGATATATCATTATGAGGTTAAGTGGCCTAAAACACTCAAT 265909
New 265911 TAATACGGATCC-TTGTACTATTAAGTCTTTTCTATCTCTGAAAATTAACTTAAGAAGCG 265969
|||||||||||| |||||||||||||||||||||||||||||||||||||||||||||||
Old 265910 TAATACGGATCCCTTGTACTATTAAGTCTTTTCTATCTCTGAAAATTAACTTAAGAAGCG 265969</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR295W YBR295W], [https://www.yeastgenome.org/locus/YBR296C YBR296C]
| 796707
| 796707
| Substitution
| A
| G
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs PCA1/YBR295W and PHO89/YBR296C.
<pre>New 796671 TAAATTAGAAAAAAATTAATGCATCTTTAAGGTTTTAAATTAGAAATGTTTTAACTTTAA 796730
|||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 796665 TAAATTAGAAAAAAATTAATGCATCTTTAAGGTTTTAAATTAAAAATGTTTTAACTTTAA 796724</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR292C YBR292C], [https://www.yeastgenome.org/locus/YBR293W YBR293W]
| 786761
| 786761
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 786736
| 786737
| Substitution
| CT
| TC
|-
| || colspan="6" | Several nucleotide changes were made in the intergenic region between ORFs YBR292C and YBR293W.
<pre>New 786721 TTCCAAATCAGATTTTTTTTCGCAATGCTTAAATCTAGTAAACACAAAGTACTACCGAAA 786780
||||||||||||||||||| |||||||||||||||||||||||| ||||||||||||||
Old 786717 TTCCAAATCAGATTTTTTTCTGCAATGCTTAAATCTAGTAAACAC-AAGTACTACCGAAA 786776
New 786761 AACACAAAGTACTACCGAAAAGCAAGGATGGAAACTATGGCAGTATTGAAGAGACTGAAA 786820
||||| ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Old 786757 AACAC-AAGTACTACCGAAAAGCAAGGATGGAAACTATGGCAGTATTGAAGAGACTGAAA 786815</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="4"| 2011-02-03
| rowspan="4"| [https://www.yeastgenome.org/locus/YBL098W YBL098W], [https://www.yeastgenome.org/locus/YBL099W YBL099W]
| 38920
| 38920
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 38917
| 38917
| Substitution
| C
| T
|- style="height:30px; width:30px; text-align:center;"
| 38800
| 38800
| Substitution
| C
| A
|- style="height:30px; width:30px; text-align:center;"
| 38728
| 38728
| Substitution
| C
| A
|-
| || colspan="6" | Several single nucleotide substitutions were made in the intergenic region between ORFs ATP1/YBL099W and BNA4/YBL098W.
<pre>New 38699 AAAAAAATAAAAATGAATATAAGGTACGTCTCAAAAAGAAATGTAAATATAGAAATTTTA 38758
|||||||||||||||||||||||||||||||| |||||||||||||||||||||||||||
Old 38696 AAAAAAATAAAAATGAATATAAGGTACGTCTCCAAAAGAAATGTAAATATAGAAATTTTA 38755
New 38759 AAAAAAAAAACGAAAAAAAACATAACTAAATTTAAAGTGCAGCCAAACAATAACCCTGAA 38818
|||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
Old 38756 AAAAAAAAAACGAAAAAAAACATAACTAAATTTAAAGTGCAGCCCAACAATAACCCTGAA 38815
New 38879 GTAAATAATGCCCCTACTTTTCTTCTAAGGAAATGAGTTACTACAAAAATAAGGAAATAT 38938
|||||||||||||||||||||||||||||||| |||||||| || |||||||||||||||
Old 38876 GTAAATAATGCCCCTACTTTTCTTCTAAGGAAGTGAGTTACCACCAAAATAAGGAAATAT 38935</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL092W YBL092W], [https://www.yeastgenome.org/locus/YBL093C YBL093C]
| 45495
| 45495
| Substitution
| T
| A
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs ROX3/YBL093C and RPL32/YBL092W.
<pre>New 45479 ACTGGAGAAGAGTGTTTGAATCCAGCAGAAGGTAATACGCACCTTTCTCATCTATTTGCA 45538
||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||
Old 45476 ACTGGAGAAGAGTGTTTGATTCCAGCAGAAGGTAATACGCACCTTTCTCATCTATTTGCA 45535</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL087C YBL087C], [https://www.yeastgenome.org/locus/YBL088C YBL088C]
| 59406
| 59406
| Insertion
|
| T
|-
| || colspan="6" | A single nucleotide insertion was made in the intergenic region between ORFs TEL1/YBL088C and RPL23A/YBL087C.
<pre>New 59399 ATTTCCCTTTTTCTTTGAAGGCTTTTTTTTCGAATTTCCTGCTTTTTTTGCGAGGCTTTG 59458
||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||
Old 59396 ATTTCCCTTTT-CTTTGAAGGCTTTTTTTTCGAATTTCCTGCTTTTTTTGCGAGGCTTTG 59454</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBL086C YBL086C], [https://www.yeastgenome.org/locus/YBL087C YBL087C]
| 61056
| 61056
| Deletion
| T
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORFs RPL23A/YBL087C and YBL086C.
<pre>New 61019 AAAAACTTGGTCTGTTGAAAATAATAACTGCATGGGTTTTT-CAAAGCAGTTGGGGGTGT 61077
||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||||
Old 61015 AAAAACTTGGTCTGTTGAAAATAATAACTGCATGGGTTTTTTCAAAGCAGTTGGGGGTGT 61074</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR205W YBR205W], [https://www.yeastgenome.org/locus/YBR207W YBR207W]
| 634934
| 634934
| Substitution
| C
| T
|-
| || colspan="6" | A single nucleotide substitution was made in the intergenic region between ORFs KTR3/YBR205W and FTH1/YBR207W.
<pre>New 634903 ATATACACATAATTCAATGTAGTAGCCACCTCACTTTATTCTAGTGCCTTCTTGGGTTCA 634962
|||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
Old 634898 ATATACACATAATTCAATGTAGTAGCCACCTCACTTCATTCTAGTGCCTTCTTGGGTTCA 634957</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2011-02-03
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR038W YBR038W], [https://www.yeastgenome.org/locus/YBR039W YBR039W]
| 315270
| 315271
| Substitution
| CG
| GC
|- style="height:30px; width:30px; text-align:center;"
| 315071
| 315071
| Deletion
| G
|
|-
| || colspan="6" | A single nucleotide deletion and a dinucleotide substitution were made in the intergenic region between ORFs CHS2/YBR038W and ATP3/YBR039W.
<pre>New 315050 TGTATGAGCTGGGCATCAAGAG-CTTTTGAGATTTTCCAAGTAGTAACTCATCTTTCTGA 315108
|||||||||||||||||||||| |||||||||||||||||||||||||||||||||||||
Old 315049 TGTATGAGCTGGGCATCAAGAGGCTTTTGAGATTTTCCAAGTAGTAACTCATCTTTCTGA 315108
New 315229 TCGATAAAACAAAAAAAAAGTAAGAAGATATATGAATAGGAGCTGTCGCTAGAACTAGTA 315288
||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Old 315229 TCGATAAAACAAAAAAAAAGTAAGAAGATATATGAATAGGACGTGTCGCTAGAACTAGTA 315288</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR036C YBR036C], [https://www.yeastgenome.org/locus/YBR037C YBR037C]
| 310457
| 310457
| Insertion
|
| T
|-
| || colspan="6" | A single nucleotide insertion was made in the intergenic region between ORFs CSG2/YBR036C and SCO1/YBR037C.
<pre>New 310430 TCCTTTAGAGTGAGAGAGCTTTTTTTTTTCTTGCGATACACCTTCGCCGGGTGATAGCCG 310489
|||||||||||||||||||||||||||| |||||||||||||||||||||||||||||||
Old 310430 TCCTTTAGAGTGAGAGAGCTTTTTTTTT-CTTGCGATACACCTTCGCCGGGTGATAGCCG 310488</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2011-02-03
| [https://www.yeastgenome.org/locus/YBR160W YBR160W], [https://www.yeastgenome.org/locus/YBR161W YBR161W]
| 561435
| 561435
| Deletion
| C
|
|-
| || colspan="6" | A single nucleotide deletion was made in the intergenic region between ORFs CDC28/YBR160W and CSH1/YBR161W.
<pre>New 561405 GCAAATTCATTGCTCTTTGAATTTTGAAGAGTTTCA-TTGTCACCGTTGAATAACCGAGA 561463
|||||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
Old 561399 GCAAATTCATTGCTCTTTGAATTTTGAAGAGTTTCACTTGTCACCGTTGAATAACCGAGA 561458</pre>
'''Engel SR, et al.''' (2014) The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) 4(3):389-98 
[http://www.yeastgenome.org/reference/24374639/overview SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/24374639 PubMed] | [http://g3journal.org/content/4/3/389 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2004-07-16
| [https://www.yeastgenome.org/locus/YBL066C YBL066C]
| 96812
| 96962
| Substitution
| GTGGTTGGATAGAGAACAGTGTTAG TCCCGTAGAATCGTGGTCGTTGTTC TATGATATCAACTTTGGAACAACTC AGAGGTGGATATCCCGTCTTTTAGA GGACCGGGGTCGGACGCGGAATCCA ACTGTCATATATTGACCGAAACAAA G
| GATGGTTTGGAAGTTAGAAGAAGTT ACAGTGTTAGTGCCCGTAGAAAATC GTTGGTTCGTTTTGTTGCTATTGAT ATCATTACTTTTGGAAAACAAGCTC AGAGGTGGATATGCCGTGCTTTTAG AGGAGCCGGGGTCGGAAACGACGGA ATGCAAATCTGTCATATTATTTGAC TTCGAAGCAATCG
|-
| || colspan="6" | SGD re-sequenced this region in S288C and found that 37 nucleotide insertions and 4 nucleotide changes were necessary to correct the reference sequence. As a consequence of these changes, SEF1/YBL066C was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 1,057 to 1,148 amino acids.
<pre>New: 1 TGTTTCCAGGAGTCTTCACGTTGTTTTCATTATCGATGGTTTGGAAGTTAGAAGAAGTTA 60
||||||||||||||||||||||||||||||||||| ||||| ||| ||| ||||
Current: 96777 TGTTTCCAGGAGTCTTCACGTTGTTTTCATTATCG-TGGTT-GGA---TAG-AGAA---- 96826

New: 61 CAGTGTTAGTGCCCGTAGAAAATCGTTGGTTCGTTTTGTTGCTATTGATATCATTACTTT 120
|||||||||| ||||||||| |||| || ||||| ||| ||| |||||||| |||||
Current: 96827 CAGTGTTAGT-CCCGTAGAA--TCGT-GG-TCGTT--GTT-CTA-TGATATCA--ACTTT 96875

New: 121 TGGAAAACAAGCTCAGAGGTGGATATGCCGTGCTTTTAGAGGAGCCGGGGTCGGAAACGA 180
|||| ||| ||||||||||||||| |||| ||||||||||| ||||||||||| ||
Current: 96876 -GGAA--CAA-CTCAGAGGTGGATATCCCGT-CTTTTAGAGGA-CCGGGGTCGGA--CG- 96926

New: 181 CGGAATGCAAATCTGTCATATTATTTGACTTCGAAGCAATCGGTGTACGTGAATGGGACA 240
|||||| ||| ||||||||| | ||||| |||| ||| |||||||||||||||||||
Current: 96927 CGGAATCCAA--CTGTCATAT-A-TTGAC--CGAAACAAA-GGTGTACGTGAATGGGACA 96979 </pre>
|- style="height:30px; width:30px; text-align:center;"
| 2004-07-13
| [https://www.yeastgenome.org/locus/YBL067C YBL067C]
| 93899
| 93899
| Insertion
|
| A
|-
| || colspan="6" | The work of Kellis et al. 2003 predicted the insertion of a single nucleotide; this sequence error was confirmed in S288C by SGD. As a consequence of this sequence change, UBP13/YBL067C was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 688 to 747 amino acids.
<pre>New: 93883 TCGCTTTATAAAACAAAACATATGCTGTTGCCATATTTGGAGATTCACCTGTGAATTCTA 93942
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old: 93883 TCGCTTTATAAAACAAA-CATATGCTGTTGCCATATTTGGAGATTCACCTGTGAATTCTA 93941 </pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| 2004-07-12
| [https://www.yeastgenome.org/locus/YBR062C YBR062C]
| 366383
| 366383
| Deletion
| T
|
|-
| || colspan="6" | The work of Cliften et al. 2003 predicted that there is a sequencing error in YBR062C: an single nucleotide should be deleted 100 nt upstream of the currently annotated start site. Assuming this sequence change, Cliften et al. further propose a new intron and 5' exon, and a framechange for this ORF. When spliced, this ORF would now encode a predicted protein of 180 amino acids. This sequence error was confirmed in S288C by SGD and the coordinates have been changed accordingly (start was moved upstream 195 nt and an intron was added at relative coordinates 17-98).
<pre> New: AAAGTTTTGAAATAGACCTTGCAGTTGGGATCT-GACCTGTCTTCTCTGCTCCTCCTGTG
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||||||
Old: AAAGTTTTGAAATAGACCTTGCAGTTGGGATCTTGACCTGTCTTCTCTGCTCCTCCTGTG </pre>
Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|- style="height:30px; width:30px; text-align:center;"
| 2004-07-09
| [https://www.yeastgenome.org/locus/YBR108W YBR108W]
| 457298
| 457298
| Insertion
|
| G
|-
| || colspan="6" | The work of Kellis et al. 2003 predicted the insertion of a single G after the G at chromosomal coordinate 457298. This sequence error was confirmed in strain S288C by SGD. As a consequence of this sequence change which caused a frameshift, YBR108W was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 848 to 947 amino acids.
<pre>New: CGGTTCGAAAAAAGTGAAGGACTCTAGCCCTGTTCCCTCAGATCTAGATGAAAAATATGT
||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||
Old: CGGTTCGAAAAAAGTGAAG-ACTCTAGCCCTGTTCCCTCAGATCTAGATGAAAAATATGT</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| 2004-01-29
| [https://www.yeastgenome.org/locus/YBL097W YBL097W]
| 40900
| 40901
| Deletion
| GA
|
|-
| || colspan="6" | Kellis et al. 2003 predicted and confirmed the deletion of two nucleotides (GA) at chromosomal coordinates 40900-40901. As a consequence of this deletion, YBL097W was extended at the 5' end, altering the N-terminus and increasing the predicted protein from 728 to 754 amino acids.
<pre>New 61 TTTACCAATAGA--TCCACCATGATGGCAAATTTTGAAGAATGGATCAAAATGGCTACAG 118
|||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||
Old 40888 TTTACCAATAGAGATCCACCATGATGGCAAATTTTGAAGAATGGATCAAAATGGCTACAG 40947</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| 2004-01-29
| [https://www.yeastgenome.org/locus/YBL013W YBL013W]
| 203180
| 203180
| Insertion
|
| C
|-
| || colspan="6" | A single C nucleotide insertion was confirmed by sequencing genomic DNA from FY23 (S288C) and a D273-10B related strain; GenBank accession number for FY23 is AY490279. The stop codon of ORF YBL013W has been moved downstream, so that the ORF is now 1206 nucleotides long as opposed to the previously annotated 1182 nt.
<pre>New 1141 GGCCAGTTCATGGCGCGCCTGCGGAAAAGATGCGGCGCCCTGAGTGAAAAGTTAGTTTTC 1200
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
Old 203163 GGCCAGTTCATGGCGCG-CTGCGGAAAAGATGCGGCGCCCTGAGTGAAAAGTTAGTTTTC 203221</pre>
|- style="height:30px; width:30px; text-align:center;"
| 2004-01-28
| [https://www.yeastgenome.org/locus/YBL006C YBL006C], [https://www.yeastgenome.org/locus/YBL006W-A YBL006W-A]
| 216785
| 216785
| Deletion
| G
|
|-
| || colspan="6" | Kellis et al. 2003 predicted and confirmed the deletion of a single nucleotide at 216785. As a consequence of this sequence change, YBL006C was extended at the 3' end, altering the C-terminus and increasing the predicted protein from 145 to 180 amino acids. In addition, YBL006W-A was extended at the 3' end, altering the C-terminus and increasing size of the predicted protein from 39 to 49 amino acids.
<pre>New 301 TCAAGTGTCGA-CTTTTCGCACCATTTCCACCGCACATTAGAATGCAAAGCTGCTCTAGA 359
||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||
Old TCAAGTGTCGACCTTTTCGCACCATTTCCACCGCACATTAGAATGCAAAGCTGCTCTAGA</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="5"| 2004-01-26
| rowspan="5"| [https://www.yeastgenome.org/locus/YBL103C-A YBL103C-A], [https://www.yeastgenome.org/locus/YBL104C YBL104C]
| 21279
| 21279
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 18364
| 18364
| Insertion
|
| G
|- style="height:30px; width:30px; text-align:center;"
| 21288
| 21288
| Insertion
|
| C
|- style="height:30px; width:30px; text-align:center;"
| 21345
| 21345
| Insertion
|
| A
|- style="height:30px; width:30px; text-align:center;"
| 21347
| 21347
| Insertion
|
| A
|-
| || colspan="6" | Brachat et al. 2003 and Kellis et al. 2003 predicted and confirmed DIFFERENT sequence changes for YBL104C. Brachat et al. demonstrated the insertion of a single G nt, which extended the 3' end by 141 nt and altered the C-terminus, resulting in overlapping ORF YBL103C-A becoming part of YBL104C (Cliften et al. also predicted this change).
<pre> New: CTTCTGTCTGCATTGGATCGCGTGATTGCGTCCCATTTATTACAAAAGGTAAGTTTGACG
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Previous: 18350 CTTCTGTCTGCATTG-ATCGCGTGATTGCGTCCCATTTATTACAAAAGGTAAGTTTGACG 18408</pre>
Kellis et al. demonstrated the insertion of four separate nucleotides (a single T, a single C, and two separate As), which extended at the 5' end by 198 nt and altered the N-terminus. The inserted C (G on the opposite, coding strand) is the third nucleotide of the new ATG start codon.
<pre> New: ATTATCATATGACCAATGGGTCACTTTTTTGATGAGACCCATGTTTATTCTTCTATACGT
||||||||||||||||||||||||||||| ||||||||| ||||||||||||||||||||
Previous: 21251 ATTATCATATGACCAATGGGTCACTTTTT-GATGAGACC-ATGTTTATTCTTCTATACGT 21308
New: TCGTGATACTGCACTTACGACTACCAGTAACATCAGAATAACCATAGAGC
||||||||||||||||||||||||||||||||||||| || |||||||||
Previous: 21309 TCGTGATACTGCACTTACGACTACCAGTAACATCAGA-TA-CCATAGAGC 21356</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Brachat S, et al.''' (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45. 
[https://www.yeastgenome.org/reference/S000073670 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12844361 PubMed] | [https://genomebiology.biomedcentral.com/articles/10.1186/gb-2003-4-7-r45 Full-Text] 
Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|- style="height:30px; width:30px; text-align:center;"
| 2004-01-21
| [https://www.yeastgenome.org/locus/YBR041W YBR041W]
| 320081
| 320082
| Deletion
| CC
|
|-
| || colspan="6" | Kellis et al. 2003 and Brachat et al. 2003 independently predicted and confirmed the deletion of two C nucleotides from YBR041W. As a consequence of this change, YBR041W was extended at the 3' end, altering the C-terminus and increasing the predicted protein from 623 to 669 amino acids.
<pre> New: TCTTATGCTATGCCCCTATTTGTTAAATTTGTTGATGAAATTAAAATGACAGATAA--TC
|||||||||||||||||||||||||||||||||||||||||||||||||||||||| ||
Previous: 320025 TCTTATGCTATGCCCCTATTTGTTAAATTTGTTGATGAAATTAAAATGACAGATAACCTC 320084</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Brachat S, et al.''' (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45. 
[https://www.yeastgenome.org/reference/S000073670 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12844361 PubMed] | [https://genomebiology.biomedcentral.com/articles/10.1186/gb-2003-4-7-r45 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2004-01-20
| [https://www.yeastgenome.org/locus/YBR157C YBR157C]
| 553996
| 553996
| Insertion
|
| G
|-
| || colspan="6" | Kellis et al. 2003 predicted and confirmed the insertion of a single G nt after the C at chromosomal coordinate 553996. As a consequence of this sequence change, YBR157C was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 106 to 255 amino acids.
<pre> New: TATGGAGGAATTTCTCCTCGTTTTCACACCATCCTTGTCTCCAGGGAAAGAGTAGGTCTT
||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||
Previous: 553978 TATGGAGGAATTTCTCCTC-TTTTCACACCATCCTTGTCTCCAGGGAAAGAGTAGGTCTT 554036</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2004-01-09
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR269C YBR269C]
| 742165
| 742165
| Insertion
|
| G
|- style="height:30px; width:30px; text-align:center;"
| 742175
| 742175
| Insertion
|
| G
|-
| || colspan="6" | Kellis et al. 2003 predicted and confirmed the insertion of G after the G at chromosomal coordinate 742165, and the insertion of another G after the G at 742175. As a consequence of these sequence changes, YBR269C was extended at the 3' end, altering the C-terminus and increasing the size of the predicted protein from 130 to 138 amino acids. This sequence change was incorporated at MIPS prior to SGD, and was verified in strain S288C.
<pre> New: ACGAATAATCGCCGTGTCTCAACGGGTCCTGCTTGGGACCCCCAACTTCACCAGTCTTGG
||||||||||||||||||||||||| |||||||||| |||||||||||||||||||||||
Previous: 742141 ACGAATAATCGCCGTGTCTCAACGG-TCCTGCTTGG-ACCCCCAACTTCACCAGTCTTGG</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 

|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 2003-09-29
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR074W YBR074W], [https://www.yeastgenome.org/locus/YBR075W YBR075W]
| 387625
| 387625
| Deletion
| G
|
|- style="height:30px; width:30px; text-align:center;"
| 387430
| 387430
| Deletion
| C
|
|-
| || colspan="6" | Due to deletion of a C after the C at position 387430 and a deletion of G after the G at position 387625, YBR074W and YBR075W were merged. After merging YBR074W (386243 - 387484 (1-1242)) and YBR075W (387793 - 389175 (1-1383)), the coordinates of the merged ORF, YBR074W, are 386243 - 389173 (1 - 2931). YBR075W is now an alias of YBR074W. These sequence changes were verified in S288c strain by SGD.
<pre>Query: 1141 TCTCGTGATAGAATGACTTGGAAATCTTATTCATGGCTATCGTGGAC-ACGCTTTCCTCT 1199
||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
Sbjct: 387383 TCTCGTGATAGAATGACTTGGAAATCTTATTCATGGCTATCGTGGACCACGCTTTCCTCT 387442
Query: 1380 AAG-CCTATCAATTATCGAATTGTTCATTATTTTATGGACCATTTTACTTTTTACGTCGA 1438
||| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Sbjct: 387623 AAGGCCTATCAATTATCGAATTGTTCATTATTTTATGGACCATTTTACTTTTTACGTCGA 387682</pre>
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Brachat S, et al.''' (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45. 
[https://www.yeastgenome.org/reference/S000073670 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12844361 PubMed] | [https://genomebiology.biomedcentral.com/articles/10.1186/gb-2003-4-7-r45 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2003-01-03
| [https://www.yeastgenome.org/locus/YBR098W YBR098W], [https://www.yeastgenome.org/locus/YBR100W YBR100W]
| 442868
| 442868
| Deletion
| C
|
|-
| || colspan="6" | Due to a change to the systematic sequence of chromosome II (C deletion at 442868), YBR098W and YBR100W have been merged to one single ORF of 691 aa. MMS4 is the standard name for the new, elongated ORF after merging; YBR100W and SLX2 are its aliases. The new coordinates of MMS4/YBR098W are 441473-443548, for a coding sequence of 2076 nt.
We thank Jim Brown (james.brown@stanford.edu), and Kirk Ehmsen (ktehmsen@ucdavis.edu) for reporting this sequence error on Chr II, which was verified in the FY1679 (S288c derivative) strain background by SGD.
<pre>Old: 442861 AGAAAACCGTTTTGATTCTATATTATGATGCGCAAGAATTTTTTGAACAATACACTTCAC 442920
||||||| ||||||||||||||||||||||||||||||||||||||||||||||||||||
New: 442861 AGAAAAC-GTTTTGATTCTATATTATGATGCGCAAGAATTTTTTGAACAATACACTTCAC 442919</pre>
'''Xiao W, et al.''' (1998) Mms4, a putative transcriptional (co)activator, protects Saccharomyces cerevisiae cells from endogenous and environmental DNA damage. Mol Gen Genet 257(6):614-23 
[https://www.yeastgenome.org/reference/S000044724 SGD paper] | [PubMed https://www.ncbi.nlm.nih.gov/pubmed/9604884] | [https://link.springer.com/article/10.1007%2Fs004380050689 Full-Text] 
'''Kaliraman V, et al.''' (2001) Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease. Genes Dev 15(20):2730-40 
[https://www.yeastgenome.org/reference/S000068964 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/11641278 PubMed] | [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC312806/ Full-Text] 
'''Kellis M, et al.''' (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54. 
[https://www.yeastgenome.org/reference/S000073327 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12748633 PubMed] | [https://www.nature.com/articles/nature01644 Full-Text] | [https://www.yeastgenome.org/reference/S000140268 Comments & Errata] 
'''Brachat S, et al.''' (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45. 
[https://www.yeastgenome.org/reference/S000073670 SGD paper] | [https://www.ncbi.nlm.nih.gov/pubmed/12844361 PubMed] | [https://genomebiology.biomedcentral.com/articles/10.1186/gb-2003-4-7-r45 Full-Text] 

|- style="height:30px; width:30px; text-align:center;"
| 2003-01-02
| [https://www.yeastgenome.org/locus/YBR086C YBR086C]
| 422272
| 422273
| Substitution
| TA
| AT
|-
| || colspan="6" | We received a direct notification from MIPS about the following sequence changes; we did not have this change in SGD, so the sequence was edited: The T at 422272 was changed to an A, and the A at 422273 was changed to a T. These differences changed amino acid residue 243 of IST2/YBR086C from Tyr (TAC) -> Ile (ATC). The coordinates of YBR086C are not changed due to this sequence update. References: (1) Sequence verification in FY1679 (S288c derivative strain) background by SGD, (2) Personal communication from Anna Kurlandzka (ania218@poczta.ibb.waw.pl).
<pre>Old: 422221 GTAGGCAAAAAAGACAAGATGGAAATCATTGGGCCGTTATAAATTTGCTTGTAGAAAATT 422280
||||||||||||||||||||||||||||||||||||||||||||||||||| |||||||
New: 422221 GTAGGCAAAAAAGACAAGATGGAAATCATTGGGCCGTTATAAATTTGCTTGATGAAAATT 422280</pre>
|- style="height:30px; width:30px; text-align:center;"
| 2001-05-29
| [https://www.yeastgenome.org/locus/YBL069W YBL069W]
| 91711
| 91711
| Deletion
| C
|
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II within the ORF AST1/YBL069W. The C at chromosomal coordinate 91711 was deleted, shifting the reading frame and moving the stop from 91722 to 92025:
<pre>Old: 91681 TTGATTCACGGCGGTGGTGCGTACGTAACCCACTGTAGGTGATTACGTTGCCAATTATAA 91740
|||||||||||||||||||||||||||||| |||||||||||||||||||||||||||||
New: 91681 TTGATTCACGGCGGTGGTGCGTACGTAACC-ACTGTAGGTGATTACGTTGCCAATTATAA 91739</pre>
|- style="height:30px; width:30px; text-align:center;"
| 2001-05-29
| [https://www.yeastgenome.org/locus/YBL004W YBL004W]
| 234918
| 234918
| Substitution
| C
| A
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II within the ORF UTP20/YBL004W. The C at chromosomal coordinate 234918 was changed to an A:
<pre>Old: 234901 CAGACCGTATTAGAAAGCAGAAAGGAAAGGAGATCTAAAAGGGCAATTCTGGCTGTTAAC 234960
||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||
New: 234901 CAGACCGTATTAGAAAGAAGAAAGGAAAGGAGATCTAAAAGGGCAATTCTGGCTGTTAAC 234960</pre>
|- style="height:30px; width:30px; text-align:center;"
| rowspan="2"| 1999-04-26
| rowspan="2"| [https://www.yeastgenome.org/locus/YBR266C YBR266C], [https://www.yeastgenome.org/locus/YBR267W YBR267W]
| 739912
| 739912
| Deletion
| A
|
|- style="height:30px; width:30px; text-align:center;"
| 739866
| 739866
| Deletion
| G
|
|-
| || colspan="6" | Two changes were made to the systematic sequence of Chromosome II within the ORF REI1/YBR267W. The G at chromosomal coordinate 739866 was deleted, and the A at 739912 was deleted; as a result, the start of YBR267W was moved 294 nt upstream.
Note that the deletion at 739912 also affects the overlapping ORF SLM6/YBR266C; as a result, the stop of YBR266C was moved 111 nt upstream:
<pre>Old: 739860 GAGCAGGCGGGCCCACATGAAGTCCGATTGGCATCGCTACAATTTGAAAAGAACGTGTTG 739919
|||||| ||||||||||||||||||||||||||||||||||||||||||||| |||||||
New: 739860 GAGCAG-CGGGCCCACATGAAGTCCGATTGGCATCGCTACAATTTGAAAAGA-CGTGTTG 739917</pre>
|- style="height:30px; width:30px; text-align:center;"
| 1999-04-26
| [https://www.yeastgenome.org/locus/YBR201W YBR201W]
| 623651
| 623651
| Deletion
| A
|
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II in the region upstream of the ORF DER1/YBR201W. The A at chromosomal coordinate 623651 was deleted. As a result, the start of YBR201W was moved upstream 210 nucleotides, increasing the size of the predicted protein from 141 to 211 amino acids.
<pre>Old: 623640 GATCCAGGGAAAGGTAGTGTACAGTTATGATTTAGTATTCAAAAAGGGACAATATGGAAG 623699
||||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||
New: 623640 GATCCAGGGAA-GGTAGTGTACAGTTATGATTTAGTATTCAAAAAGGGACAATATGGAAG 623698</pre>
|- style="height:30px; width:30px; text-align:center;"
| 1999-04-26
| [https://www.yeastgenome.org/locus/YBR294W YBR294W]
| 791709
| 791709
| Substitution
| T
| C
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II within the ORF SUL1/YBR294W. The T at chromosomal coordinate 791709 was changed to a C:
<pre>Old: 791700 TATGTGCTGTAACTGGGACAAATTTACCGTTTTTTCATATCGATATACCCGATTTTTCTA 791759
||||||||| ||||||||||||||||||||||||||||||||||||||||||||||||||
New: 791700 TATGTGCTGCAACTGGGACAAATTTACCGTTTTTTCATATCGATATACCCGATTTTTCTA 791759</pre>
|- style="height:30px; width:30px; text-align:center;"
| rowspan="3"| 1999-04-26
| rowspan="3"| [https://www.yeastgenome.org/locus/YBR069C YBR069C], [https://www.yeastgenome.org/locus/YBR070C YBR070C]
| 378824
| 378824
| Insertion
|
| C
|- style="height:30px; width:30px; text-align:center;"
| 378810
| 378810
| Insertion
|
| T
|- style="height:30px; width:30px; text-align:center;"
| 378815
| 378815
| Deletion
| C
|
|-
| || colspan="6" | Three changes were made to the systematic sequence of Chromosome II in the intergenic region between the ORFs TAT1/YBR069C and ALG14/YBR070C. A single T was inserted after the T at chromosomal coordinate 378810, the C at 378815 was deleted, and a C was inserted after the G at 378824:
<pre>Old: 378781 GCCGGCCCTGACTGACCTTTTTTGTATTTT-GGCCCGTCCCGGCG-GGCGAAGAGTGAGAC 378839
|||||||||||||||||||||||||||||| |||| ||||||||| |||||||||||||||
New: 378781 GCCGGCCCTGACTGACCTTTTTTGTATTTTTGGCC-GTCCCGGCGCGGCGAAGAGTGAGAC 378840</pre>
|- style="height:30px; width:30px; text-align:center;"
| 1999-04-23
| [https://www.yeastgenome.org/locus/YBL067C YBL067C]
| 94040
| 94040
| Substitution
| G
| C
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II within the ORF UBP13/YBL067C. The G at chromosomal coordinate 94040 was changed to a C:
<pre>Old: 94021 CATAATGGCCGTGTTGTGGGCCACCGCCCATATGAACGACAATCCCAGCCAATTCATACT 94080
||||||||||||||||||| ||||||||||||||||||||||||||||||||||||||||
New: 94021 CATAATGGCCGTGTTGTGGCCCACCGCCCATATGAACGACAATCCCAGCCAATTCATACT 94080</pre>
|- style="height:30px; width:30px; text-align:center;"
| rowspan="4"| 1999-04-23
| rowspan="4"| [https://www.yeastgenome.org/locus/YBR006W YBR006W]
| 247367
| 247367
| Substitution
| C
| T
|- style="height:30px; width:30px; text-align:center;"
| 248539
| 248539
| Substitution
| A
| T
|- style="height:30px; width:30px; text-align:center;"
| 248278
| 248278
| Substitution
| A
| T
|- style="height:30px; width:30px; text-align:center;"
| 247262
| 247262
| Substitution
| C
| G
|-
| || colspan="6" | Three single nucleotide (nt) substitutions were made to the systematic sequence of Chromosome II within the ORF UGA2/YBR006W, and one substitution was made in the adjacent intergenic region. The C at chromosomal coordinate 247262 was changed to a G, the C at 247367 was changed to a T, the A at 248278 was changed to a T (destroying the stop codon), and the A at 248539 was changed to a T. As a result, the stop was moved 186 nucleotides downstream, increasing the size of the coding sequence from 1308 nt to 1494 nt.
<pre>Old: 247261 TCGCAACCATCATTACTTTAGAAAATGGTAAAGCTCTAGGGGAAGCTAAAGGAGAAATCA 247320
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
New: 247261 TGGCAACCATCATTACTTTAGAAAATGGTAAAGCTCTAGGGGAAGCTAAAGGAGAAATCA 247320
Old: 247321 AATACGCGGCTTCGTATTTTGAGTGGTACGCCGAGGAAGCACCCCGCTTATATGGTGCTA 247380
|||||||||||||||||||||||||||||||||||||||||||||| |||||||||||||
New: 247321 AATACGCGGCTTCGTATTTTGAGTGGTACGCCGAGGAAGCACCCCGTTTATATGGTGCTA 247380
Old: 248221 CTAATGATACTGAGTTTGGTTTAGCAGCATATGTCTTTTCTAAAAATGTCAACACTTAAT 248280
||||||||||||||||||||||||||||||||||||||||||||||||||||||||| ||
New: 248221 CTAATGATACTGAGTTTGGTTTAGCAGCATATGTCTTTTCTAAAAATGTCAACACTTTAT 248280
Old: 248521 GTATATATCTATTGCATGAATAAATACTCTACTCCTCGTATATAGAAAGTTAAGTAAATT 248580
|||||||||||||||||| |||||||||||||||||||||||||||||||||||||||||
New: 248521 GTATATATCTATTGCATGTATAAATACTCTACTCCTCGTATATAGAAAGTTAAGTAAATT 248580</pre>
|- style="height:30px; width:30px; text-align:center;"
| 1999-04-23
| [https://www.yeastgenome.org/locus/YBL066C YBL066C]
| 97484
| 97485
| Substitution
| TG
| GC
|-
| || colspan="6" | A change was made to the systematic sequence of Chromosome II within the ORF SEF1/YBL066C. The two nucleotides TG at positions 575 and 576 (chromosomal coordinates 97484-97485) were changed to GC, altering translation by changing amino acid 192 from Gln (CAA) to Ala (GCA). Note that this ORF is on the Crick strand.
<pre>Old: 97441 AGAACCGTCAGAATCTCCGTTATTTGTCTTGGCTAGCTTTTCTTGCTGCTTTAAGGCATT 97500
||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||
New: 97441 AGAACCGTCAGAATCTCCGTTATTTGTCTTGGCTAGCTTTTCTGCCTGCTTTAAGGCATT 97500</pre>
'''Cherry JM, et al.''' (1998) "Genetic and Physical Maps of Saccharomyces cerevisiae (Edition 15)". Pp. 414-420 in 1998 Yeast Genetics and Molecular Biology Meeting Program and Abstracts. Bethesda, MD: The Genetics Society of America 
[https://www.yeastgenome.org/reference/S000076263 SGD paper]

|- style="height:30px; width:30px; text-align:center;"
| 1999-04-22
| [https://www.yeastgenome.org/locus/YBL033C YBL033C]
| 159114
| 159114
| Substitution
| C
| G
|-
| || colspan="6" | The C at chromosomal coordinate 159114 within the ORF RIB1/YBL033C was changed to a G, altering translation by changing amino acid 181 from Lys (AAG) to Asn (AAC). Note that this ORF is on the Crick strand:
<pre>Old: 159061 CGACCCTCTTGTCTTAGATACACGATAACACCATGGCCGTTTCCACCTTTGATCTTGCTT 159120
||||||||||||||||||||||||||||||||||||||||||||||||||||| ||||||
New: 159061 CGACCCTCTTGTCTTAGATACACGATAACACCATGGCCGTTTCCACCTTTGATGTTGCTT 159120</pre>
'''Cherry JM, et al.''' (1998) "Genetic and Physical Maps of Saccharomyces cerevisiae (Edition 15)". Pp. 414-420 in 1998 Yeast Genetics and Molecular Biology Meeting Program and Abstracts. Bethesda, MD: The Genetics Society of America 
[https://www.yeastgenome.org/reference/S000076263 SGD paper]

|- style="height:30px; width:30px; text-align:center;"
| rowspan="6"| 1998-09-13
| rowspan="6"| [https://www.yeastgenome.org/locus/YBL101C YBL101C]
| 25408
| 25408
| Insertion
|
| C
|- style="height:30px; width:30px; text-align:center;"
| 28272
| 28272
| Insertion
|
| G
|- style="height:30px; width:30px; text-align:center;"
| 28296
| 28296
| Insertion
|
| C
|- style="height:30px; width:30px; text-align:center;"
| 25394
| 25394
| Deletion
| T
|
|- style="height:30px; width:30px; text-align:center;"
| 28306
| 28306
| Substitution
| A
| G
|- style="height:30px; width:30px; text-align:center;"
| 28302
| 28302
| Insertion
|
| GG
|-
| || colspan="6" | Six changes were made to the systematic sequence of Chromosome II within the ORF ECM21/YBL101C and in the adjacent intergenic region. Within the ORF, the T at chromosomal coordinate 25394 was deleted, and a single C was inserted after the C at 25408:
<pre>Old: 25381 CGGCATCATCGCTTGTATCCGGATGGCC-ACTAACTGACGTAGTTCTTGATAAGTTCAAT 25439
||||||||||||| |||||||||||||| |||||||||||||||||||||||||||||||
New: 25381 CGGCATCATCGCT-GTATCCGGATGGCCCACTAACTGACGTAGTTCTTGATAAGTTCAAT 25439</pre>
Upstream of the ORF, a single G was inserted after the G at 28272, a single C was inserted after the C at 28296, two nucleotides (nt) GG were inserted after the G at 28302, and the A at 28306 was changed to a G:
<pre>Old: 28260 TTTTTCGCCACCG-TCTTGATGTTATAAACGGCATGCC-AATAGG--TAGAGAAAAATCT 28315
||||||||||||| |||||||||||||||||||||||| |||||| ||| |||||||||
New: 28260 TTTTTCGCCACCGGTCTTGATGTTATAAACGGCATGCCCAATAGGGGTAGGGAAAAATCT 28319</pre>
The start site of YBL101C was then moved upstream, extending the size of the coding region from 3234 nt to 3354 nt, and the size of the predicted protein from 728 amino acids (aa) to 754 aa.

|- style="height:30px; width:30px; text-align:center;"
| 1997-07-27
| [https://www.yeastgenome.org/locus/YBL091C YBL091C]
| 48615
| 48615
| Substitution
| A
| C
|-
| || colspan="6" | The A at chromosomal coordinate 48615 (upstream of the Crick strand ORF MAP2/YBL091C at coordinates 48402-47353) was changed to a C, and the start site of YBL091C was then moved 216 nucleotides (nt) upstream to the newly-created start codon, extending the size of the coding sequence from 1050 nt to 1266 nt, the size of the predicted protein from 349 amino acids (aa) to 421 aa. Note that the sequence presented below is from the Watson strand:
<pre>New: 48600 TATTTCAGCGTCTGTCATTTTTCAATACGGTAGAGCTTCTACAGTACTTGTTGATGTAAA 48659
||||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
Old: 48600 TATTTCAGCGTCTGTAATTTTTCAATACGGTAGAGCTTCTACAGTACTTGTTGATGTAAA 48659</pre>
|- style="height:30px; width:30px; text-align:center;"
| 1997-07-27
| [https://www.yeastgenome.org/locus/YBL103C YBL103C]
| 22603
| 22603
| Insertion
|
| G
|-
| || colspan="6" | A single G was inserted after the G at chromosomal coordinate 22603 within the ORF RTG3/YBL103C, shifting the frame and extending the 3' end by 510 nucleotides:
<pre>New: 22561 TACCTAGGTCATCGTAATTCAATAAAGATGGTGGAACCAACTGGCCGAGTTCTTTTATCT 22620
||||||||||||||||||||||||||||||||||||||||||| ||||||||||||||||
Old: 22561 TACCTAGGTCATCGTAATTCAATAAAGATGGTGGAACCAACTG-CCGAGTTCTTTTATCT 22619</pre>
|}

=Annotation Changes=
{| class="wikitable" style="border-spacing: 2px; border: 1px solid darkgray;"
! Date !! Affected Features
|-
| 2014-11-18|| TLC1
|-
| || style="border: 1px solid darkgray;" |The feature_type annotation of TLC1 was changed from ncRNA to telomerase_RNA_gene (SO:0001643) as part of SGD's genome annotation revision R64.2.
|-
| 2014-11-18|| ARS207, ARS208, ARS209, ARS211, ARS214, ARS216, ARS217, ARS224, ARS231
|-
| || style="border: 1px solid darkgray;" |As part of SGD's genome annotation revision R64.2, new ARS consensus sequences were annotated within the following ARS elements on Chromosome II based on Liachko et al. 2013: ARS207, ARS231, ARS208, ARS209, ARS211, ARS214, ARS216, ARS217, ARS224.
Liachko I, et al. (2013) High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast. Genome Res 23(4):698-704

|-
| 2014-11-18|| ARS202, ARS207, ARS208, ARS209, ARS214, ARS224, ARS228, ARS231
|-
| || style="border: 1px solid darkgray;" |The chromosomal coordinates of the following ARS elements on Chromosome II were updated based on Liachko et al. 2013 as part of SGD's genome annotation revision R64.2: ARS202, ARS207, ARS231, ARS208, ARS209, ARS214, ARS224, ARS228.
Liachko I, et al. (2013) High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast. Genome Res 23(4):698-704

|-
| 2014-11-18|| ARS200, ARS201, ARS203, ARS206, ARS217
|-
| || style="border: 1px solid darkgray;" |The following new ARS elements on Chromosome II were added to the genome annotation based on Liachko et al. 2013 as part of SGD's genome annotation revision R64.2: ARS200, ARS201, ARS203, ARS206, ARS217.
Liachko I, et al. (2013) High-resolution mapping, characterization, and optimization of autonomously replicating sequences in yeast. Genome Res 23(4):698-704

|-
| 2014-11-18|| ETC8
|-
| || style="border: 1px solid darkgray;" |The following previously unmapped features were identified as nuclear matrix attachment sites and assigned chromosomal coordinates based on Hiraga et al. 2012 as part of SGD's genome annotation revision R64.2: ETC1, ETC2, ETC3, ETC4, ETC6, ETC7, ETC8.
Hiraga SI, et al. (2012) TFIIIC localizes budding yeast ETC sites to the nuclear periphery. Mol Biol Cell 23(14):2741-54

|-
| 2009-05-07|| YBR073W
|-
| || style="border: 1px solid darkgray;" |The start site for RDH54/YBR073W was reinstated 102 nt (34 codons) upstream. This is a reversal of the start site change made to this ORF on 2003-09-22. Thank you to Nancy Hollingsworth for bringing this issue to our attention.
Shinohara M, et al. (1997) Characterization of the roles of the Saccharomyces cerevisiae RAD54 gene and a homologue of RAD54, RDH54/TID1, in mitosis and meiosis. Genetics 147(4):1545-56

Petukhova G, et al. (2000) Promotion of Rad51-dependent D-loop formation by yeast recombination factor Rdh54/Tid1. Genes Dev 14(17):2206-15

Chi P, et al. (2006) Yeast recombination factor Rdh54 functionally interacts with the Rad51 recombinase and catalyzes Rad51 removal from DNA. J Biol Chem 281(36):26268-79

Kwon Y, et al. (2008) ATP-dependent Chromatin Remodeling by the Saccharomyces cerevisiae Homologous Recombination Factor Rdh54. J Biol Chem 283(16):10445-52

|-
| 2009-05-07|| ARS212, ARS213, ARS221
|-
| || style="border: 1px solid darkgray;" |The following ARS elements on Chromosome 2 were added to the genome annotation based on Raveendranathan et al. 2006: ARS212, ARS213, and ARS221.
Raveendranathan M, et al. (2006) Genome-wide replication profiles of S-phase checkpoint mutants reveal fragile sites in yeast. EMBO J 25(15):3627-39

|-
| 2007-07-09|| YBR215W
|-
| || style="border: 1px solid darkgray;" |The start of ORF HPC2/YBR215W was moved 90 nt upstream and an intron was added at relative coordinates 14..97 based on GenBank EF123149 and Juneau et al. 2007. According to Juneau et al. 2007, the intron is "inefficiently spliced" (splicing rate 85%). The ORF had been annotated as 1872 nt long, but is now 1962 nt in length.
Juneau K, et al. (2007) High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing. Proc Natl Acad Sci U S A 104(5):1522-7

|-
| 2007-04-05|| YBLCdelta7, YBRCdelta11, YBRCdelta14, YBRCdelta19
|-
| || style="border: 1px solid darkgray;" |The following Ty1 LTRs on Chromosome II were mistakenly annotated on the wrong strand (i.e., on Watson instead of Crick); the error has now been corrected, so that the LTRs are annotated on the Crick strand: YBLCdelta7, YBRCdelta11, YBRCdelta14, YBRCdelta19.
|-
| 2007-04-05|| YBRCtau2
|-
| || style="border: 1px solid darkgray;" |YBRWtau2, a Ty4 LTR on Chromosome II, was mistakenly annotated on the wrong strand (i.e., on Watson instead of Crick). Both the orientation and the feature name have been corrected, so that the LTR now has the systematic name YBRCtau2 and is annotated on the Crick strand. The name YBRWtau2 is being retained as an alias.
|-
| 2007-04-05|| YBLCtau1
|-
| || style="border: 1px solid darkgray;" |YBLWtau1, a Ty4 LTR on Chromosome II, was mistakenly annotated on the wrong strand (i.e., on Watson instead of Crick). Both the orientation and the feature name have been corrected, so that the LTR now has the systematic name YBLCtau1 and is annotated on the Crick strand. The name YBLWtau1 is being retained as an alias.
|-
| 2007-04-04|| YBR089C-A
|-
| || style="border: 1px solid darkgray;" |NHP6B/YBR089C-A mRNA contains an intron in the 5' untranslated region (UTR).
Miura F, et al. (2006) A large-scale full-length cDNA analysis to explore the budding yeast transcriptome. Proc Natl Acad Sci U S A 103(47):17846-51

Juneau K, et al. (2007) High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing. Proc Natl Acad Sci U S A 104(5):1522-7

|-
| 2007-04-04|| YBL092W
|-
| || style="border: 1px solid darkgray;" |RPL32/YBL092W mRNA contains an intron in the 5' untranslated region (UTR).
Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

Miura F, et al. (2006) A large-scale full-length cDNA analysis to explore the budding yeast transcriptome. Proc Natl Acad Sci U S A 103(47):17846-51

Juneau K, et al. (2007) High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing. Proc Natl Acad Sci U S A 104(5):1522-7

|-
| 2007-04-04|| YBL072C
|-
| || style="border: 1px solid darkgray;" |RPS8A/YBL072C mRNA contains an intron in the 5' untranslated region (UTR).
Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

Miura F, et al. (2006) A large-scale full-length cDNA analysis to explore the budding yeast transcriptome. Proc Natl Acad Sci U S A 103(47):17846-51

Juneau K, et al. (2007) High-density yeast-tiling array reveals previously undiscovered introns and extensive regulation of meiotic splicing. Proc Natl Acad Sci U S A 104(5):1522-7

|-
| 2006-10-04|| LSR1
|-
| || style="border: 1px solid darkgray;" |The start site and the stop site for LSR1/snR20 (aka U2 snRNA) were each moved 4 nt upstream, to the positions determined by Ares M. Jr. (1986). Thanks to Wayne Decatur for bringing this update to our attention.
Ares M Jr (1986) U2 RNA from yeast is unexpectedly large and contains homology to vertebrate U4, U5, and U6 small nuclear RNAs. Cell 47(1):49-59

|-
| 2006-10-02|| ARS230, ARS231
|-
| || style="border: 1px solid darkgray;" |ARS230 (also known as ARS201.5) and ARS231 (also known as ARS207.5) were added to the genome annotation based on Nieduszynski et al. 2006.
Nieduszynski CA, et al. (2006) Genome-wide identification of replication origins in yeast by comparative genomics. Genes Dev 20(14):1874-9

|-
| 2006-09-07|| ARS202, ARS207, ARS208, ARS211, ARS214, ARS215, ARS216, ARS220, ARS222, ARS224, ARS225, ARS228
|-
| || style="border: 1px solid darkgray;" |The following ARS elements on Chromosome II were added to SGD based on Nieduszynski et al. 2006: ARS202, ARS207, ARS208, ARS211, ARS214, ARS215, ARS216, ARS220, ARS222, ARS224, ARS225, ARS228.
Nieduszynski CA, et al. (2006) Genome-wide identification of replication origins in yeast by comparative genomics. Genes Dev 20(14):1874-9

|-
| 2006-03-02|| ARS209
|-
| || style="border: 1px solid darkgray;" |This new ARS element ARS209 was added to the genome annotation based on Bouton & Smith 1986 and Wyrick et al. 2001.
Wyrick JJ, et al. (2001) Genome-wide distribution of ORC and MCM proteins in S. cerevisiae: high-resolution mapping of replication origins. Science 294(5550):2357-60

Bouton AH and Smith MM (1986) Fine-structure analysis of the DNA sequence requirements for autonomous replication of Saccharomyces cerevisiae plasmids. Mol Cell Biol 6(7):2354-63

|-
| 2005-11-10|| snR161
|-
| || style="border: 1px solid darkgray;" |New snoRNA, snR161, added based on the work of Olivas et al. 1997 and Schattner et al. 2004. Note that Olivas et al. refer to this snoRNA as RNA161.
Olivas WM, et al. (1997) Analysis of the yeast genome: identification of new non-coding and small ORF-containing RNAs. Nucleic Acids Res 25(22):4619-25

Schattner P, et al. (2004) Genome-wide searching for pseudouridylation guide snoRNAs: analysis of the Saccharomyces cerevisiae genome. Nucleic Acids Res 32(14):4281-96

|-
| 2005-11-08|| YBR056C-B, YBR201C-A
|-
| || style="border: 1px solid darkgray;" |Based on comparisons of the genome sequences of six Saccharomyces species, Cliften et al. 2003 suggested that two new ORFs, YBR056C-B and YBR201C-A, be added to the S. cerevisiae genome annotation.
Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2005-11-07|| YBR286W
|-
| || style="border: 1px solid darkgray;" |After consultation with MIPS, SGD will incorporate the annotation change suggested by Kellis et al. 2003 for APE3/YBR286W. The start site is being moved 78 nt downstream from chromosomal coordinate 774618 to 774696, resulting in a predicted protein of 537 aa, as opposed to the previously annotated 563 aa. The 1692-nt ORF is now 1614 nt.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

|-
| 2004-10-12|| CEN2
|-
| || style="border: 1px solid darkgray;" |Centromeric DNA elements CDEI, CDEII, and CDEIII were annotated based on Wieland et al. 2001 and Espelin et al. 2003.
Wieland G, et al. (2001) Determination of the binding constants of the centromere protein Cbf1 to all 16 centromere DNAs of Saccharomyces cerevisiae. Nucleic Acids Res 29(5):1054-60

Espelin CW, et al. (2003) Binding of the essential Saccharomyces cerevisiae kinetochore protein Ndc10p to CDEII. Mol Biol Cell 14(11):4557-68

|-
| 2004-04-01|| RUF8
|-
| || style="border: 1px solid darkgray;" |Feature annotation removed per John McCutcheon and Sean Eddy.
McCutcheon J and Eddy S (2004) Corrigendum: Computational identification of non-coding RNAs in Saccharomyces cerevisiae by comparative genomics Nucleic Acids Res 32 (15):4713

|-
| 2004-04-01|| YBR230W-A
|-
| || style="border: 1px solid darkgray;" |ORF identified by John McCutcheon and Sean Eddy.
McCutcheon JP and Eddy SR (2003) Computational identification of non-coding RNAs in Saccharomyces cerevisiae by comparative genomics. Nucleic Acids Res 31(14):4119-28

|-
| 2004-01-07|| YBL091C-A
|-
| || style="border: 1px solid darkgray;" |Based on comparison to related fungi, Brachat et al., Blandin et al., and Cliften et al. all proposed an intron and 5' extension for YBL091C-A. The resulting ORF is in the same frame with the start codon shifted 316 bp upstream; the protein has a 76-residue extension at the N-terminus.
Blandin G, et al. (2000) Genomic exploration of the hemiascomycetous yeasts: 4. The genome of Saccharomyces cerevisiae revisited. FEBS Lett 487(1):31-6

Brachat S, et al. (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-12-17|| YBR111W-A
|-
| || style="border: 1px solid darkgray;" |The size of the first intron of YBR111W-A was increased and a second intron was added on the basis of conserved splice sites predicted by Cliften et al. 2003, as well as subsequent experimental evidence (GenBank AY278445). The chromosomal coordinates of the coding sequence have changed from 462094-462172..462175-462392 to 462094-462164..462245-462384..462455-462534.
Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-12-17|| YBR255C-A
|-
| || style="border: 1px solid darkgray;" |The boundaries of the intron in ORF YBR255C-A were shifted by 1 bp on 5' end and 2 bp on 3' end on basis of conserved splice sites in other fungal species as predicted by Blandin et al. 2000.
Blandin G, et al. (2000) Genomic exploration of the hemiascomycetous yeasts: 4. The genome of Saccharomyces cerevisiae revisited. FEBS Lett 487(1):31-6

|-
| 2003-09-22|| YBR280C
|-
| || style="border: 1px solid darkgray;" |The start site for YBR280C was moved 15 nt (5 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBR172C
|-
| || style="border: 1px solid darkgray;" |The start site for SMY2/YBR172C was moved 150 nt (50 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBL089W
|-
| || style="border: 1px solid darkgray;" |The start site for AVT5/YBL089W was moved 150 nt (50 codons) downstream based on the automated comparison of closely related Saccharomyces species by Kellis et al. 2003. The numbering for both the nucleotides in the DNA coding sequence and the amino acids in the predicted protein have been updated. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBL068W
|-
| || style="border: 1px solid darkgray;" |The start site for PRS4/YBL068W was moved 84 nt (28 codons) downstream based on the automated comparison of closely related Saccharomyces species by Kellis et al. 2003. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBR095C
|-
| || style="border: 1px solid darkgray;" |The start site for YBR095C was moved 69 nt (23 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBR073W
|-
| || style="border: 1px solid darkgray;" |The start site for RDH54/YBR073W was moved 102 nt (34 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBR058C
|-
| || style="border: 1px solid darkgray;" |The start site for UBP14/YBR058C was moved 66 nt (22 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBR122C
|-
| || style="border: 1px solid darkgray;" |The start site for MRPL36/YBR122C was moved 57 nt (19 codons) downstream based on the automated comparison of closely-related Saccharomyces species. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine; 3) The predicted protein translated from the conserved methionine contains a predicted mitochondrial targeting signal sequence (using both MitoProt (MIPS) and Predotar), while the predicted protein translated from the previously annotated S. cerevisiae start codon does not.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBR264C
|-
| || style="border: 1px solid darkgray;" |The start site for YPT10/YBR264C was moved 57 nt (19 codons) downstream based on the automated comparison of closely-related Saccharomyces species by Kellis et al. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-22|| YBR263W
|-
| || style="border: 1px solid darkgray;" |The start site for SHM1/YBR263W was moved 225 nt (75 codons) downstream based on the automated comparison of closely-related Saccharomyces species by Kellis et al. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.
Kellis M, et al. (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54

Cliften P, et al. (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6

|-
| 2003-09-09|| TEL02L, TEL02R
|-
| || style="border: 1px solid darkgray;" |The chromosomal locations for the following telomeric elements on Chromosome 2 were generously provided by Ed Louis and Dave Barton (University of Leicester, UK): TEL02L, TEL02L-XC, TEL02L-XR, TEL02L-YP, TEL02R, TEL02R-XC, TEL02R-XR, TEL02R-TR.

Note that TEL02L does have telomeric repeats (TEL02L-TR), but they are missing from the genome annotation due to sequencing difficulties encountered during the initial genome sequencing efforts in the 1990s.
|-
| 2003-07-29|| YBL039C-A, YBR121C-A, YBR196C-B, YBR221W-A
|-
| || style="border: 1px solid darkgray;" |Thanks to Oshiro et al., Velculescu et al., and Basrai et al. for providing the coordinates of the following four ORFs on Chromosome 2: YBL039C-A, YBR121C-A, YBR196C-B, YBR221W-A.
Basrai MA, et al. (1999) NORF5/HUG1 is a component of the MEC1-mediated checkpoint response to DNA damage and replication arrest in Saccharomyces cerevisiae. Mol Cell Biol 19(10):7041-9

Velculescu VE, et al. (1997) Characterization of the yeast transcriptome. Cell 88(2):243-51

Oshiro G, et al. (2002) Parallel identification of new genes in Saccharomyces cerevisiae. Genome Res 12(8):1210-20

|-
| 2003-07-29|| YBR056W-A, YBR109W-A, YBR126W-B
|-
| || style="border: 1px solid darkgray;" |Thanks to MIPS for providing the coordinates of the following three ORFs on Chromosome 2: YBR056W-A, YBR109W-A, YBR126W-B.
|-
| 2003-07-29|| YBL006W-A, YBL071C-B, YBL100W-C, YBL113W-A, YBR126W-A, YBR131C-A, YBR141W-A, YBR182C-A, YBR223W-A, YBR296C-A, YBR298C-A
|-
| || style="border: 1px solid darkgray;" |Thanks to Kumar et al. for providing the coordinates of the following 11 ORFs on Chromosome 2: YBL006W-A, YBL071C-B, YBL101W-C, YBL113W-A, YBR126W-A, YBR131C-A, YBR141W-A, YBR182C-A, YBR223W-A, YBR296C-A, YBR298C-A.
Kumar A, et al. (2002) An integrated approach for finding overlooked genes in yeast. Nat Biotechnol 20(1):58-63

|-
| 2003-07-29|| YBL008W-A, YBL068W-A, YBL103C-A, YBR072C-A, YBR076C-A, YBR196C-A, YBR200W-A
|-
| || style="border: 1px solid darkgray;" |Thanks to Kessler et al. for providing the coordinates of the following seven ORFs on Chromosome 2: YBL008W-A, YBL068W-A, YBL103C-A, YBR072C-A, YBR076C-A, YBR196C-A, YBR200W-A.
Kessler MM, et al. (2003) Systematic discovery of new genes in the Saccharomyces cerevisiae genome. Genome Res 13(2):264-71

|-
| 2003-07-29|| YBL039W-B, YBR111W-A
|-
| || style="border: 1px solid darkgray;" |Thanks to Brachat et al. for providing the coordinates of the following two ORFs on Chromosome 2 based on homology to Ashbya gossypii: YBL039W-B, YBR111W-A.
Brachat S, et al. (2003) Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Genome Biol 4(7):R45

|-
| 2003-03-06|| RUF8
|-
| || style="border: 1px solid darkgray;" |Thanks to John McCutcheon and Sean Eddy for providing the coordinates for the following RNA features: SNR82, SNR83, SNR84, RUF4, RUF5-1, RUF5-2, RUF6, RUF7, and RUF8.
McCutcheon JP and Eddy SR (2003) Computational identification of non-coding RNAs in Saccharomyces cerevisiae by comparative genomics. Nucleic Acids Res 31(14):4119-28

|-
| 2001-01-30|| YBL071W-A
|-
| || style="border: 1px solid darkgray;" |ORF added based on similarity to an S. pombe gene (information submitted by Valerie Wood).
|-
| 2000-08-11|| YBR089C-A
|-
| || style="border: 1px solid darkgray;" |old name: YBR090C-A; new name: YBR089C-A; date: 11/1998; old coord: ChrII 426447 426148; SGDID: S0002157; Name changed due to nomenclature
|-
| 2000-07-14|| YBR186W
|-
| || style="border: 1px solid darkgray;" |Davis et al. demonstrated an intron and 3' exon in PCH2/YBR186W that were not previously annotated. The addition of this intron and exon alters the C-terminus of the protein product and increases the protein size from 537 to 564 amino acids.
Davis CA, et al. (2000) Test of intron predictions reveals novel splice sites, alternatively spliced mRNAs and new introns in meiotically regulated genes of yeast. Nucleic Acids Res 28(8):1700-6

|-
| 1999-11-17|| YBL059C-A
|-
| || style="border: 1px solid darkgray;" |A new ORF, YBL059C-A, was identified from EST analysis (Evan Hurowitz in Pat Brown's lab).
|-
| 1998-05-21|| YBL091C-A, YBL107W-A
|-
| || style="border: 1px solid darkgray;" |The following 27 ORFs were added to the genome annotation based on Velculescu et al. 1997: YBL091C-A, YBL107W-A, YCR018C-A, YCR102W-A, YDL130W-A, YDR034C-A, YDR034W-B, YDR363W-A, YDR525W-A, YER048W-A, YER091C-A, YER138W-A, YGR122C-A, YIR020W-B, YKL033W-A, YKL053C-A, YKL162C-A, YLL018C-A, YLR262C-A, YML081C-A, YMR046W-A, YMR158C-B, YMR194C-A, YNR032C-A, YOL013W-A, YOR298C-A, and YPR002C-A.

|}