YLR038C

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Systematic name YLR038C
Gene name COX12
Aliases
Feature type ORF, Verified
Coordinates Chr XII:225172..224921
Primary SGDID S000004028


Description of YLR038C: Subunit VIb of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; required for assembly of cytochrome c oxidase but not required for activity after assembly; phosphorylated[1][2]




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Protein Details

Other Protein Details

Other Topic: Regulated by the diauxic shift (glycerol)

Apart form the overall increase in mitochondrial protein mass after the diauxic shift this protein remains unchanged after the diauxic shift. [3] [4]





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References

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  1. LaMarche AE, et al. (1992) Isolation and characterization of COX12, the nuclear gene for a previously unrecognized subunit of Saccharomyces cerevisiae cytochrome c oxidase. J Biol Chem 267(31):22473-80 SGD PMID 1331057
  2. Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906 SGD PMID 17761666
  3. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  4. submitted by Steffen Ohlmeier on 2004-04-08

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