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Systematic name YER014W
Gene name HEM14
Feature type ORF, Verified
Coordinates Chr V:182600..184219
Primary SGDID S000000816

Description of YER014W: Protoporphyrinogen oxidase, a mitochondrial enzyme that catalyzes the seventh step in the heme biosynthetic pathway, converting protoporphyrinogen IX to protoporphyrin IX; inhibited by diphenyl ether-type herbicides[1][2][3]


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  1. Camadro JM and Labbe P (1996) Cloning and characterization of the yeast HEM14 gene coding for protoporphyrinogen oxidase, the molecular target of diphenyl ether-type herbicides. J Biol Chem 271(15):9120-8 SGD PMID 8621563
  2. Glerum DM, et al. (1996) Cloning and identification of HEM14, the yeast gene for mitochondrial protoporphyrinogen oxidase. Yeast 12(14):1421-5 SGD PMID 8948097
  3. Urban-Grimal D and Labbe-Bois R (1981) Genetic and biochemical characterization of mutants of Saccharomyces cerevisiae blocked in six different steps of heme biosynthesis. Mol Gen Genet 183(1):85-92 SGD PMID 7035824

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