Difference between revisions of "Positions in yeast labs"

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=='''Postdoctoral position in Cell Biology, Univ. of Miami, Florida (posted December 2014)''' ==
== POSTDOCTORAL POSITION - NIH, National Cancer Institute, Posted April 16, 2014 ==
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'''
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A Postdoctoral position is available in the lab of Dr. Sandra Lemmon, University of Miami, Miller School of Medicine. Research focuses on regulation of membrane dynamics in the yeast S. cerevisiae.
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Qualifications: Candidates should have a PhD in chemistry, biology, genetics or a related life science. Applicants with a background in cell biology, yeast genetics and molecular biology, fluorescence microscopy and/or lipid biochemistry are especially encouraged to apply. Please submit a curriculum vitae, publications, summary of past research experiences, research interests, and the names of three references to: Dr. Sandra Lemmon at <slemmon[at]miami[dot]edu>.
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=='''Postdoctoral position for yeast experimental evolution available in the Sherlock lab @ Stanford, posted November 2014''' ==
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The Sherlock lab has a postdoctoral position available immediately to work on experimental evolution using yeast as a model system.  We have developed a lineage tracking system, which allows us to follow cultures as they evolve, and determine when new beneficial mutations emerge.  The goal of the project is to understand how the beneficial mutation rate and the distribution of fitness effects, as well as the identity of the beneficial mutations themselves, changes due to a different, more fit founding genotype in an experimental evolution.  Experience with yeast is strongly desired, and ability to program and perform data analysis would be beneficial.  Please see:
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http://web.stanford.edu/group/sherlocklab/join.shtml
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for details on how to join the lab.
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=='''Bioinformatician / computational biologist position in yeast biology & next generation sequencing''' ==
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Laboratory of Biology of Yeast Colonies (www.natur.cuni.cz/~zdenap), Faculty of Science, Charles University in Prague is seeking applicants for researcher position in the field of bioinformatics.
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DESCRIPTION:
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BIOINFORMATICIAN / COMPUTATIONAL BIOLOGIST POSITION funded by Czech-Norwegian Research Program is available at the Group of Biology of Yeast Colonies (www.natur.cuni.cz/~zdenap), Faculty of Science, Charles University in Prague, Vinicna 5, Prague, Czech Republic, being a part of new scientific center of excellence “Biotechnology and Biomedicine Center of the Academy of Sciences and Charles University in Vestec”.
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The Research Group is interested in different aspects of yeast multicellularity including questions related to topics of cell ageing, stress defense, adaptation and longevity. The research of the group currently follows two main lines: i) Development, differentiation and signaling of yeast colonies as a model of a primitive multicellular organism, with the main goal to identify the regulatory networks and signals involved in the phenotypic differentiation between the different types of chronologically aged cells developing within the colony (related to Mol Cell 46: 436-448, 2012). ii) Development, defense strategies and signaling pathways involved in formation of biofilm colonies of wild yeast (related to J Cell Biol. 194:679-87, 2011). The candidates (i.e. bioinformaticians / computational biologists, alternatively informaticians / statisticians / big data analysts) should be interested in applying their skills in both research directions; in particular, the challenges of integrating the DNA, RNA and epigenetic data obtained by next-generation DNA/RNA sequencing methodology. The project will produce a unique dataset where the cells have been characterized at the fundamental levels of molecular biology (genetics, epigenetics and expression). We envisage that such a complete dataset will facilitate unique novel insights into the biology of the yeast model system. The bioinformatician will be expected to play a central role in data processing, integration and analysis.
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QUALIFICATION AND EXPERIENCE: Candidates should be comfortable at the unix / linux command line and preferably also able to write bash scripts. The candidate should also be able to program in at least one of the following languages: perl, python, java, c++, and be familiar with statistical software (preferably R). Familiarity with high through-put sequencing software is a plus: mapping tools (e.g. bwa, novoalign), expression quantification (e.g. tophat), variant calling (e.g. GATK), peak calling (e.g. MACS). Last, but not least, the candidate should be interested in applying these quantitative skills to biological data.
 +
ELIGIBILITY, HOW TO APPLY: The applicants should have good command of English and preferentially a PhD; however, researchers who have completed University education without PhD, proficient in the tools described above, are also encouraged to apply. Please send your motivation letter, CV, list of publications (including IF and the number of citations) and reference contacts directly to the group leader Zdena Palkova (zdenap@natur.cuni.cz). The contract is available from January 1, 2015 (or by appointment) and finishes at April 2017.
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=='''PhD and Post-doctoral positions in the lab of Martin Kupiec (genome stability) at Tel Aviv University, Israel, posted November 2014''' ==
 +
We are looking highly motivated people to work on Genome Stability and telomeres in yeast. The lab http://www.tau.ac.il/lifesci/departments/biotech/members/kupiec/kupiec.html
 +
works on processes that prevent cancer by keeping the genome stable. These include the repair of broken chromosomes, the handling of stalled DNA replication forks and the maintenance of normal-length telomeres. Candidates should send a Curriculum Vitae, including past research experiences and publication records, as well as a letter detailing their motivation and interest in our work. Applicants should also request recommendation letters to be directly sent by two or three references.
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== '''Technician/Research assistant position available''' ==
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A 3-year technician/research assistant position is available in the group of Dr. Damien Coudreuse (www.synthecell.org) at the Institute of Genetics and Development of Rennes (IGDR), France (http://igdr.univ-rennes1.fr/english/). Research in this laboratory takes a synthetic biology approach in fission yeast to study the architecture and evolution of cell cycle regulation. Routinely used techniques in the team include fission yeast genetics, molecular biology (DNA, RNA and protein biology) and microscopy. The role of the technician/engineer will be to provide help with such techniques to various members of the team as well as to take responsibility for a number of common tasks in the laboratory.Candidates should contact Dr. Damien Coudreuse at damien.coudreuse@univ-rennes1.fr and send a Curriculum Vitae, including past experiences, as well as a letter detailing their motivation and interest in the position. Applicants should also request recommendation letters to be directly sent by one to three references.
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== '''Post-doctoral positions available - Complexity and Variability in Cell Proliferation''' ==
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Two three-year post-doctoral positions supported by a starting grant from the European Research Council (ERC) are available in the group of Dr. Damien Coudreuse (www.synthecell.org) at the Institute of Genetics and Development of Rennes (IGDR), France (http://igdr.univ-rennes1.fr/english/). Research in this laboratory takes a synthetic biology approach in fission yeast to study the architecture and evolution of cell cycle regulation. The proposed projects aim at understanding fundamental aspects of the control of cell proliferation, from the buffering of variability in the different mechanisms driving cell cycle progression to the evolution of complexity in cell cycle control.Candidates should contact Dr. Damien Coudreuse at damien.coudreuse@univ-rennes1.fr and send a Curriculum Vitae, including past research experiences and publication records, as well as a letter detailing their motivation and interest in our work. Applicants should also request recommendation letters to be directly sent by two or three references.
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== '''POSTDOCTORAL POSITION - NIH, National Cancer Institute, Posted April 16, 2014''' ==
 +
 
 
A postdoctoral position is available within the Optical Imaging Core of the Laboratory of Receptor Biology and Gene Expression (NCI/NIH) to conduct research in the regulation of transcription in Saccharomyces cerevisiae. The candidate is expected to have a background in yeast genetics and molecular biology and to be interested in extensive live imaging by fluorescence microscopy and in super-resolution methods.
 
A postdoctoral position is available within the Optical Imaging Core of the Laboratory of Receptor Biology and Gene Expression (NCI/NIH) to conduct research in the regulation of transcription in Saccharomyces cerevisiae. The candidate is expected to have a background in yeast genetics and molecular biology and to be interested in extensive live imaging by fluorescence microscopy and in super-resolution methods.
 
Publications in the area of research:
 
Publications in the area of research:
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=='''Postdoctoral position in Cell Biology, Univ. of Miami, Florida (posted April 2014)'''==
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=='''Postdoctoral Fellowship in yeast evolutionary genomics at Stanford University''', March 2014==
 
 
A Postdoctoral position is available in the lab of Dr. Sandra Lemmon, University of Miami, Miller School of Medicine.  Research focuses on regulation of membrane dynamics in the yeast S. cerevisiae.  Particular interests include the role of phosphorylation, the actin cytoskeleton, and lipids in endocytosis and the function of clathrin in endocytosis and sorting to the lysosome/vacuole. For information on research interests check: <http://biomed.miami.edu/?p=482&pid=208&m=facultyph&mid=0&item=9>. 
 
 
 
Qualifications:  Candidates should have a PhD in chemistry, biology, genetics or a related life science.  Applicants with a background in cell biology, yeast genetics and molecular biology, fluorescence microscopy and/or lipid biochemistry are especially encouraged to apply. Please submit a curriculum vitae, publications, summary of past research experiences, research interests, and the names of three references to:  Dr. Sandra Lemmon at <slemmon[at]miami[dot]edu>.
 
 
 
 
 
=='''Postdoctoral Fellowship in yeast evolutionary genomics at Stanford University'''==
 
  
 
The Fraser Lab in the Department of Biology is seeking a postdoctoral fellow to work on the evolution of gene expression in Saccharomyces yeast.  The exact subject is flexible, but will likely involve using RNA-seq to answer fundamental questions about the mechanisms and consequences of gene expression evolution- especially in cases of evolutionary adaptations.  The ideal candidate would have experience in yeast molecular biology techniques, as well as some familiarity with computational and/or evolutionary analysis.  Salary and benefits are both above the NIH standards for postdocs.  Please email a cover letter and CV to hbfraser[at]stanford[dot]edu.
 
The Fraser Lab in the Department of Biology is seeking a postdoctoral fellow to work on the evolution of gene expression in Saccharomyces yeast.  The exact subject is flexible, but will likely involve using RNA-seq to answer fundamental questions about the mechanisms and consequences of gene expression evolution- especially in cases of evolutionary adaptations.  The ideal candidate would have experience in yeast molecular biology techniques, as well as some familiarity with computational and/or evolutionary analysis.  Salary and benefits are both above the NIH standards for postdocs.  Please email a cover letter and CV to hbfraser[at]stanford[dot]edu.
  
=='''Research Associate position (Ph.D. level) at Stanford University'''==
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=='''Research Associate position (Ph.D. level) at Stanford University''', March 2014==
  
 
The Fraser Lab in the Department of Biology is seeking a Basic Life Science Research Associate (Ph.D. level). We apply the exciting tools of genomics and high-throughput sequencing to study the evolution of gene expression in a variety of species, but primarily budding yeast. Duties will include:
 
The Fraser Lab in the Department of Biology is seeking a Basic Life Science Research Associate (Ph.D. level). We apply the exciting tools of genomics and high-throughput sequencing to study the evolution of gene expression in a variety of species, but primarily budding yeast. Duties will include:
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=='''Postdoctoral fellowship in cell cycle evolution at the Institute of Genetics and Development of Rennes, France'''==
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=='''Postdoctoral fellowship in cell cycle evolution at the Institute of Genetics and Development of Rennes, France''', January 2014==
  
 
A three-year post-doctoral position supported by a starting grant from the European Research Council (ERC) is available in the group of Dr. Damien Coudreuse at the Institute of Genetics and Development of Rennes (IGDR), France (http://igdr.univ-rennes1.fr/english/). Research in this laboratory takes a synthetic biology approach in fission yeast to study the architecture and evolution of cell cycle regulation. The proposed project aims at understanding fundamental aspects of the evolution of cell proliferation, from how cells overcome external challenges to common features of independent evolutionary processes. It will be based on the use of fission yeast cells operating with various minimal cell cycle control circuits as starting points for experimental evolution approaches. Candidates should contact Dr. Damien Coudreuse at damien.coudreuse@univ-rennes1.fr and send a Curriculum Vitae, including past research experiences and publication records, as well as a letter detailing their motivation and interest in our work. Applicants should also request recommendation letters to be directly sent by two or three references.
 
A three-year post-doctoral position supported by a starting grant from the European Research Council (ERC) is available in the group of Dr. Damien Coudreuse at the Institute of Genetics and Development of Rennes (IGDR), France (http://igdr.univ-rennes1.fr/english/). Research in this laboratory takes a synthetic biology approach in fission yeast to study the architecture and evolution of cell cycle regulation. The proposed project aims at understanding fundamental aspects of the evolution of cell proliferation, from how cells overcome external challenges to common features of independent evolutionary processes. It will be based on the use of fission yeast cells operating with various minimal cell cycle control circuits as starting points for experimental evolution approaches. Candidates should contact Dr. Damien Coudreuse at damien.coudreuse@univ-rennes1.fr and send a Curriculum Vitae, including past research experiences and publication records, as well as a letter detailing their motivation and interest in our work. Applicants should also request recommendation letters to be directly sent by two or three references.
 
 
=='''Postdoctoral Fellowship in Cell Fate and Gene Regulation (POS00123), LRI/Crick Institute, London, UK'''==
 
 
We seek a talented and motivated Postdoc to join the Cell Fate and Gene Regulation Laboratory in London, UK. The Cell Fate and Gene Regulation laboratory headed by Dr Folkert van Werven will be opened in the fall of this year.  It will be a small, highly interactive, international research group that focuses on understanding the molecular mechanisms of how cell fate decisions are controlled. Initially we will use budding yeast as a model system, and take molecular, systematic and quantitative approaches (including single-molecule, proteomic, and genomic techniques) to study this problem. For more information please send an email (Folkert.vanWerven at cancer.org.uk) or go to:
 
https://cruk.taleo.net/careersection/cruk_corporate/jobdetail.ftl?lang=en&job=POS00123&view=rss
 
 
 
=='''Postdoctoral Position in Biology of Yeast Colonies at Charles University in Prague, Czech Republic'''==
 
 
Postdoctoral positions are available in the lab of Zdena Palkova (http://www.natur.cuni.cz/~zdenap). The Research Group is interested in different aspects of yeast multicellularity including questions related to topics of yeast cell differentiation, ageing, stress defense, adaptation and longevity that are crucial in any organism, including humans.
 
 
Selected recent references:
 
• Cap M, Stepanek L, Harant K, Vachova L, Palkova Z. (2012) Cell differentiation within a yeast colony: metabolic and regulatory parallels with a tumor-affected organism. Mol Cell 46: 436-448
 
• Vachova L, Stovicek V, Hlavacek O, Chernyavskiy O, Stepanek L, Kubinová L, Palkova Z. (2011) Flo11p, drug efflux pumps, and the extracellular matrix cooperate to form biofilm yeast colonies. J Cell Biol. 194: 679-87.
 
 
Candidates should have experience in molecular and cellular biology and methodical knowledge in techniques of yeast cell growth and manipulation. In addition, candidates should have high motivation and ability to work independently and take responsibility for his/her own project as well as to work in a team.
 
 
The applicants should have (i) a recent PhD (the degree obtained no earlier than on 28th of March 2008), (ii) promising publication record and be able to speak fluent English (or Czech). Please send your motivation letter (<500 words), CV, list of publications (including IF and the number of citations) and contact information of three references directly to the group leader Zdena Palkova,  mailto:zdenap@natur.cuni.cz (please combine all documents into single PDF file). Applications will be considered until suitable candidates are found. The positions include additional funds for the international mobility (3 months).
 
 
 
=='''PhD student in Molecular Biology (Marie Curie Early Stage Researcher)at the University of Gothenburg, Sweden'''==
 
A PhD student position in Molecular Biology/Systems Biology is available in the lab of Prof. Stefan Hohmann, Dept of Cell and Molecular Biology, University of Gothenburg, Sweden.
 
 
The research project “Experimental investigation of the yeast Hxk2/Snf1/Mig1 network” aims to understand the dynamic control of the Hxk2/Snf1/Mig1 glucose signalling pathway employing single cell technology developed in the ISOLATE project. Here the experimental platform generated in the project will be optimized, especially the formation of cell arrays of synchronized cells as well as image analysis. Using in parallel Mig1 and Msn2 reporters, response thresholds under different glucose levels will be establish and effects on cell-to-cell variability and bistability will be determined.
 
 
Requested Background(advantageous but not required): Yeast biology, yeast genetics, glucose signalling, use of microfluidic devices, microscopy, image analysis, application of nano-sensor technology, ‘systems’ thinking.
 
 
The Marie Curie project ISOLATE is a collaborative research and training network between eight partners, incl. in different European countries. The PhD students and postdocs in the project will perform top-notch research and will additionally benefit from an excellent training network offered by the project partners. Research stays during the PhD projects in other partners’ labs are strongly encouraged. Primarily recruitment of researchers from EC Member States and associated countries, but also open to researchers from third countries. Researchers are normally required to move from one country to another when taking up the appointment.
 
 
Please send an application including (1) a max. one-page cover letter containing a justification why this position was chosen as well as a career vision statement, (2) a complete CV with details on education, previous research activities and a list of publications (if any,)(3) a copy of the passport or ID with picture, (4) two letters of recommendation, to maria.enge@gu.se (Project Manager in Prof. Hohmann's group).
 
 
=='''PhD student in Systems Biology (Marie Curie Early Stage Researcher)at the University of Gothenburg, Sweden'''==
 
 
A PhD student position in Systems Biology is available in the lab of Prof. Stefan Hohmann, Dept of Cell and Molecular Biology, University of Gothenburg, Sweden.
 
 
The research project “Theoretical investigation of the yeast Hxk2/Snf1/Mig1 network” aims to understand the dynamic control of the Hxk2/Snf1/Mig1 glucose signalling pathway employing single cell technology developed in the ISOLATE project. Data generated in the project will be interpreted by mathematical modelling together with other project partners to understand feedback and feed-forward mechanisms of signalling. Mutants and inhibitory compounds will be used to test how those affect thresholds and bistability. The analysis will reveal the genetic determination of the system properties, how they are regulated and how robustness against perturbation is established.
 
 
Requested Background(advantageous but not required): Yeast biology, yeast genetics, glucose signaling, microscopy, image analysis, development of mathematical models, ‘systems’ thinking.
 
 
The Marie Curie project ISOLATE is a collaborative research and training network between eight partners, incl. in different European countries. The PhD students and postdocs in the project will perform top-notch research and will additionally benefit from an excellent training network offered by the project partners. Research stays during the PhD projects in other partners’ labs are strongly encouraged. Primarily recruitment of researchers from EC Member States and associated countries, but also open to researchers from third countries. Researchers are normally required to move from one country to another when taking up the appointment.
 
 
Please send an application including (1) a max. one-page cover letter containing a justification why this position was chosen as well as a career vision statement, (2) a complete CV with details on education, previous research activities and a list of publications (if any,)(3) a copy of the passport or ID with picture, (4) two letters of recommendation, to maria.enge@gu.se (Project Manager in Prof. Hohmann's group).
 
 
=='''Postdoctoral position to study Ty1 retrotransposition at the University of Georgia''' ==
 
 
A postdoctoral position is available in the lab of David J. Garfinkel, Department of Biochemistry and Molecular Biology, University of Georgia, Athens GA to work on the retrovirus-like transposon Ty1 of ''Saccharomyces''. Specifically, we are investigating a new form of RNA-interference based on Ty1 antisense RNAs that acts posttranslationally and targets Ty1 proteins in the absence of the conserved RNAi pathways.
 
 
Experience in molecular genetics, protein/nucleic acid interactions or cytology would be helpful.
 
 
Also see our website for further information [http://www.bmb.uga.edu/home/people/people.php?fname=David&lname=Garfinkel]
 
 
Please send resume or inquiries to:
 
David J. Garfinkel
 
Department of Biochemistry and Molecular Biology
 
A130 Life Sciences
 
120 Green St.
 
University of Georgia
 
Athens, GA 30622
 
 
tel: 706-542-9403
 
djgarf@bmb.uga.edu
 
 
==Yeast Systems Biology Position at Virginia Tech (Research Associate or Sr Research Associate)==
 
The Synthetic Biology group at Virginia Bioinformatics Institute (VBI) is involved in two collaborative research projects focused on the development of mathematical models of gene-protein regulatory networks controlling cell growth and division. Temporal organization of the budding yeast cell cycle has been studied from two vantage points: bottom-up models emphasize a protein regulatory network centered around cyclin-dependent protein kinases, whereas top-down models focus on a gene regulatory network governed by interrelated transcription factors. The first project is focused on unifying these two perspectives. The second project is focused on the development of stochastic models of the regulatory network controlling the cell cycle. Both projects are performed in close collaboration with experts in computer science, data mining, bioinformatics, and mathematical modeling. The successful candidate will be expected to contribute significantly to these two projects by being responsible for designing and performing experiments used to validate model predictions. These experiments will involve the development of a new collection of cell cycle mutants and their quantitative characterization by time-lapse microscopy. In addition, the successful candidate will be expected to prepare the results for publication and presentation, to help supervise graduate and undergraduate students, and to contribute to grant proposals.
 
 
Dependent on the qualifications of the successful candidate, the position will hold the research faculty rank of either Research Associate or Senior Research Associate.
 
 
Go to the [http://bit.ly/n4nDUQ position description] for additional information and for submitting applications. 
 
 
More information about our team can be found by visiting:
 
* [http://www.vbi.vt.edu/faculty/personal/Jean_Peccoud Jean Peccoud's home page]
 
* [http://www.biol.vt.edu/faculty/tyson/ John Tyson's home page]
 
* [https://bioinformatics.cs.vt.edu/~murali/ T.M. Murali's home page]
 
 
==Postdoctoral position - Laboratory of Cell Physics - Strasbourg, France==
 
Postdoctoral position is available in the Laboratory of Cell Physics, ISIS/IGBMC, Strasbourg, France. The project will focus on the dynamics of the cytokinetic ring in the fission yeast S. pombe. The roles of the Rho GTPase, actin polymerisation, and myosin will be studied. The work will involve genetics, cell biology, microscopy, microfabrication and microfluidics; for more information, send a CV and contact information of referees to Dr. Daniel Riveline (riveline@unistra.fr)
 

Revision as of 19:11, 4 December 2014

Postdoctoral position in Cell Biology, Univ. of Miami, Florida (posted December 2014)

A Postdoctoral position is available in the lab of Dr. Sandra Lemmon, University of Miami, Miller School of Medicine. Research focuses on regulation of membrane dynamics in the yeast S. cerevisiae.

Qualifications: Candidates should have a PhD in chemistry, biology, genetics or a related life science. Applicants with a background in cell biology, yeast genetics and molecular biology, fluorescence microscopy and/or lipid biochemistry are especially encouraged to apply. Please submit a curriculum vitae, publications, summary of past research experiences, research interests, and the names of three references to: Dr. Sandra Lemmon at <slemmon[at]miami[dot]edu>.

Postdoctoral position for yeast experimental evolution available in the Sherlock lab @ Stanford, posted November 2014

The Sherlock lab has a postdoctoral position available immediately to work on experimental evolution using yeast as a model system. We have developed a lineage tracking system, which allows us to follow cultures as they evolve, and determine when new beneficial mutations emerge. The goal of the project is to understand how the beneficial mutation rate and the distribution of fitness effects, as well as the identity of the beneficial mutations themselves, changes due to a different, more fit founding genotype in an experimental evolution. Experience with yeast is strongly desired, and ability to program and perform data analysis would be beneficial. Please see:

http://web.stanford.edu/group/sherlocklab/join.shtml

for details on how to join the lab.

Bioinformatician / computational biologist position in yeast biology & next generation sequencing

Laboratory of Biology of Yeast Colonies (www.natur.cuni.cz/~zdenap), Faculty of Science, Charles University in Prague is seeking applicants for researcher position in the field of bioinformatics. DESCRIPTION: BIOINFORMATICIAN / COMPUTATIONAL BIOLOGIST POSITION funded by Czech-Norwegian Research Program is available at the Group of Biology of Yeast Colonies (www.natur.cuni.cz/~zdenap), Faculty of Science, Charles University in Prague, Vinicna 5, Prague, Czech Republic, being a part of new scientific center of excellence “Biotechnology and Biomedicine Center of the Academy of Sciences and Charles University in Vestec”. The Research Group is interested in different aspects of yeast multicellularity including questions related to topics of cell ageing, stress defense, adaptation and longevity. The research of the group currently follows two main lines: i) Development, differentiation and signaling of yeast colonies as a model of a primitive multicellular organism, with the main goal to identify the regulatory networks and signals involved in the phenotypic differentiation between the different types of chronologically aged cells developing within the colony (related to Mol Cell 46: 436-448, 2012). ii) Development, defense strategies and signaling pathways involved in formation of biofilm colonies of wild yeast (related to J Cell Biol. 194:679-87, 2011). The candidates (i.e. bioinformaticians / computational biologists, alternatively informaticians / statisticians / big data analysts) should be interested in applying their skills in both research directions; in particular, the challenges of integrating the DNA, RNA and epigenetic data obtained by next-generation DNA/RNA sequencing methodology. The project will produce a unique dataset where the cells have been characterized at the fundamental levels of molecular biology (genetics, epigenetics and expression). We envisage that such a complete dataset will facilitate unique novel insights into the biology of the yeast model system. The bioinformatician will be expected to play a central role in data processing, integration and analysis. QUALIFICATION AND EXPERIENCE: Candidates should be comfortable at the unix / linux command line and preferably also able to write bash scripts. The candidate should also be able to program in at least one of the following languages: perl, python, java, c++, and be familiar with statistical software (preferably R). Familiarity with high through-put sequencing software is a plus: mapping tools (e.g. bwa, novoalign), expression quantification (e.g. tophat), variant calling (e.g. GATK), peak calling (e.g. MACS). Last, but not least, the candidate should be interested in applying these quantitative skills to biological data. ELIGIBILITY, HOW TO APPLY: The applicants should have good command of English and preferentially a PhD; however, researchers who have completed University education without PhD, proficient in the tools described above, are also encouraged to apply. Please send your motivation letter, CV, list of publications (including IF and the number of citations) and reference contacts directly to the group leader Zdena Palkova (zdenap@natur.cuni.cz). The contract is available from January 1, 2015 (or by appointment) and finishes at April 2017.

PhD and Post-doctoral positions in the lab of Martin Kupiec (genome stability) at Tel Aviv University, Israel, posted November 2014

We are looking highly motivated people to work on Genome Stability and telomeres in yeast. The lab http://www.tau.ac.il/lifesci/departments/biotech/members/kupiec/kupiec.html works on processes that prevent cancer by keeping the genome stable. These include the repair of broken chromosomes, the handling of stalled DNA replication forks and the maintenance of normal-length telomeres. Candidates should send a Curriculum Vitae, including past research experiences and publication records, as well as a letter detailing their motivation and interest in our work. Applicants should also request recommendation letters to be directly sent by two or three references.

Technician/Research assistant position available

A 3-year technician/research assistant position is available in the group of Dr. Damien Coudreuse (www.synthecell.org) at the Institute of Genetics and Development of Rennes (IGDR), France (http://igdr.univ-rennes1.fr/english/). Research in this laboratory takes a synthetic biology approach in fission yeast to study the architecture and evolution of cell cycle regulation. Routinely used techniques in the team include fission yeast genetics, molecular biology (DNA, RNA and protein biology) and microscopy. The role of the technician/engineer will be to provide help with such techniques to various members of the team as well as to take responsibility for a number of common tasks in the laboratory.Candidates should contact Dr. Damien Coudreuse at damien.coudreuse@univ-rennes1.fr and send a Curriculum Vitae, including past experiences, as well as a letter detailing their motivation and interest in the position. Applicants should also request recommendation letters to be directly sent by one to three references.


Post-doctoral positions available - Complexity and Variability in Cell Proliferation

Two three-year post-doctoral positions supported by a starting grant from the European Research Council (ERC) are available in the group of Dr. Damien Coudreuse (www.synthecell.org) at the Institute of Genetics and Development of Rennes (IGDR), France (http://igdr.univ-rennes1.fr/english/). Research in this laboratory takes a synthetic biology approach in fission yeast to study the architecture and evolution of cell cycle regulation. The proposed projects aim at understanding fundamental aspects of the control of cell proliferation, from the buffering of variability in the different mechanisms driving cell cycle progression to the evolution of complexity in cell cycle control.Candidates should contact Dr. Damien Coudreuse at damien.coudreuse@univ-rennes1.fr and send a Curriculum Vitae, including past research experiences and publication records, as well as a letter detailing their motivation and interest in our work. Applicants should also request recommendation letters to be directly sent by two or three references.


POSTDOCTORAL POSITION - NIH, National Cancer Institute, Posted April 16, 2014

A postdoctoral position is available within the Optical Imaging Core of the Laboratory of Receptor Biology and Gene Expression (NCI/NIH) to conduct research in the regulation of transcription in Saccharomyces cerevisiae. The candidate is expected to have a background in yeast genetics and molecular biology and to be interested in extensive live imaging by fluorescence microscopy and in super-resolution methods. Publications in the area of research: Tatiana S. Karpova, Teresa Y. Chen, Brian L. Sprague, James G. McNally. Dynamic interactions of a transcription factor with DNA are accelerated by a chromatin remodeler. EMBO Reports. 5: 1064-1070, 2004 Tatiana S. Karpova, Min J. Kim, Corentin Spriet, Kip Nalley, Tim Stasevich, Zoulika Kherrouche, Laurent Heliot, and James G. McNally. Concurrent Fast and Slow Cycling of a Transcriptional Activator at an Endogenous Promoter. Science 319: 466-469, 2008 Applicants should contact Dr. Tatiana Karpova (karpovat@mail.nih.gov) and submit their CV.

Opening for two postdoctoral positions in the Cell Signaling Research Group, UPF, Barcelona, Spain (posted April 2014)

Post description: We offer two postdoctoral research positions in the Cell Signaling Research Group led by Dr. Francesc Posas and Dr. Eulàlia de Nadal), at the Pompeu Fabra University, Barcelona, Spain. The main objective of our group is the study of the molecular mechanisms of signal transduction mediated by SAPKs (Stress Activated Protein Kinases) in yeast cells, as well as to understand the complexity of adaptive responses generated by these enzymes. Regulation of gene expression and cell cycle are two of the most important aspects for cell adaptation to stress [Nadal-Ribelles M. et al, Mol Cell (2014); Duch A. et al, Nature (2013); Nadal-Ribelles M. et al, Genome Biol (2012); de Nadal E. and Posas F., Nat. Rev. Genet. (2011); Solé C. et al., EMBO J (2011); Regot S. et al., Nature (2011)]. We are looking for a highly motivated research scientist with consolidated experience in biochemistry and/or yeast genetics to work in these fields.

The Institute: UPF is a young, public and modern university and called to become one of the leading European universities. Awarded with a CEI label (International Excellence Campus) by the Spanish Ministry of Education, UPF's indicators have made it a benchmark for the Spanish and European university systems. Our group is integrated into the Biomedical Research Park of Barcelona (PRBB), one of the largest hubs of biomedical research in southern Europe.

For more information please visit the web site: http://www.upf.edu/cellsignaling


Postdoctoral Fellowship in yeast evolutionary genomics at Stanford University, March 2014

The Fraser Lab in the Department of Biology is seeking a postdoctoral fellow to work on the evolution of gene expression in Saccharomyces yeast. The exact subject is flexible, but will likely involve using RNA-seq to answer fundamental questions about the mechanisms and consequences of gene expression evolution- especially in cases of evolutionary adaptations. The ideal candidate would have experience in yeast molecular biology techniques, as well as some familiarity with computational and/or evolutionary analysis. Salary and benefits are both above the NIH standards for postdocs. Please email a cover letter and CV to hbfraser[at]stanford[dot]edu.

Research Associate position (Ph.D. level) at Stanford University, March 2014

The Fraser Lab in the Department of Biology is seeking a Basic Life Science Research Associate (Ph.D. level). We apply the exciting tools of genomics and high-throughput sequencing to study the evolution of gene expression in a variety of species, but primarily budding yeast. Duties will include:

• Performing a wide range of experiments with the yeast S. cerevisiae. These will focus on a revolutionary new tool in molecular biology: genetic engineering via the CRISPR/Cas system. Other experiments will include gene knockout/replacement, chromatin immunoprecipitation, and high-throughput sequencing of mRNA. • Teaching experimental protocols to others in the lab • Keeping the lab's yeast strains/chemicals organized • Overseeing an undergraduate student for dishwashing/media preparation

A Ph.D. in a Biology-related field is required, with at least 2 years spent working with S. cerevisiae. Also desirable (but not required) is experience with: mammalian cell culture, chromatin immunoprecipitation, and/or high-throughput sequencing. Please email a cover letter and CV to hbfraser[at]stanford[dot]edu.


Postdoctoral fellowship in cell cycle evolution at the Institute of Genetics and Development of Rennes, France, January 2014

A three-year post-doctoral position supported by a starting grant from the European Research Council (ERC) is available in the group of Dr. Damien Coudreuse at the Institute of Genetics and Development of Rennes (IGDR), France (http://igdr.univ-rennes1.fr/english/). Research in this laboratory takes a synthetic biology approach in fission yeast to study the architecture and evolution of cell cycle regulation. The proposed project aims at understanding fundamental aspects of the evolution of cell proliferation, from how cells overcome external challenges to common features of independent evolutionary processes. It will be based on the use of fission yeast cells operating with various minimal cell cycle control circuits as starting points for experimental evolution approaches. Candidates should contact Dr. Damien Coudreuse at damien.coudreuse@univ-rennes1.fr and send a Curriculum Vitae, including past research experiences and publication records, as well as a letter detailing their motivation and interest in our work. Applicants should also request recommendation letters to be directly sent by two or three references.