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=='''Postdoctoral Position in Biology of Yeast Colonies at Charles University in Prague, Czech Republic'''==
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== '''Technician/Research assistant position available''' ==
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A 3-year technician/research assistant position is available in the group of Dr. Damien Coudreuse (www.synthecell.org) at the Institute of Genetics and Development of Rennes (IGDR), France (http://igdr.univ-rennes1.fr/english/). Research in this laboratory takes a synthetic biology approach in fission yeast to study the architecture and evolution of cell cycle regulation. Routinely used techniques in the team include fission yeast genetics, molecular biology (DNA, RNA and protein biology) and microscopy. The role of the technician/engineer will be to provide help with such techniques to various members of the team as well as to take responsibility for a number of common tasks in the laboratory.Candidates should contact Dr. Damien Coudreuse at damien.coudreuse@univ-rennes1.fr and send a Curriculum Vitae, including past experiences, as well as a letter detailing their motivation and interest in the position. Applicants should also request recommendation letters to be directly sent by one to three references.
  
Postdoctoral positions are available in the lab of Zdena Palkova (http://www.natur.cuni.cz/~zdenap). The Research Group is interested in different aspects of yeast multicellularity including questions related to topics of yeast cell differentiation, ageing, stress defense, adaptation and longevity that are crucial in any organism, including humans.
 
  
Selected recent references:
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== '''Post-doctoral positions available - Complexity and Variability in Cell Proliferation''' ==
• Cap M, Stepanek L, Harant K, Vachova L, Palkova Z. (2012) Cell differentiation within a yeast colony: metabolic and regulatory parallels with a tumor-affected organism. Mol Cell 46: 436-448
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Two three-year post-doctoral positions supported by a starting grant from the European Research Council (ERC) are available in the group of Dr. Damien Coudreuse (www.synthecell.org) at the Institute of Genetics and Development of Rennes (IGDR), France (http://igdr.univ-rennes1.fr/english/). Research in this laboratory takes a synthetic biology approach in fission yeast to study the architecture and evolution of cell cycle regulation. The proposed projects aim at understanding fundamental aspects of the control of cell proliferation, from the buffering of variability in the different mechanisms driving cell cycle progression to the evolution of complexity in cell cycle control.Candidates should contact Dr. Damien Coudreuse at damien.coudreuse@univ-rennes1.fr and send a Curriculum Vitae, including past research experiences and publication records, as well as a letter detailing their motivation and interest in our work. Applicants should also request recommendation letters to be directly sent by two or three references.
• Vachova L, Stovicek V, Hlavacek O, Chernyavskiy O, Stepanek L, Kubinová L, Palkova Z. (2011) Flo11p, drug efflux pumps, and the extracellular matrix cooperate to form biofilm yeast colonies. J Cell Biol. 194: 679-87.  
 
  
Candidates should have experience in molecular and cellular biology and methodical knowledge in techniques of yeast cell growth and manipulation. In addition, candidates should have high motivation and ability to work independently and take responsibility for his/her own project as well as to work in a team.
 
  
The applicants should have (i) a recent PhD (the degree obtained no earlier than on 28th of March 2008), (ii) promising publication record and be able to speak fluent English (or Czech). Please send your motivation letter (<500 words), CV, list of publications (including IF and the number of citations) and contact information of three references directly to the group leader Zdena Palkova,  mailto:zdenap@natur.cuni.cz (please combine all documents into single PDF file). Applications will be considered until suitable candidates are found. The positions include additional funds for the international mobility (3 months).
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== '''POSTDOCTORAL POSITION - NIH, National Cancer Institute, Posted April 16, 2014''' ==
  
=='''Postdoctoral Position in Chemical Genomics at RIKEN ASI'''==
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A postdoctoral position is available within the Optical Imaging Core of the Laboratory of Receptor Biology and Gene Expression (NCI/NIH) to conduct research in the regulation of transcription in Saccharomyces cerevisiae. The candidate is expected to have a background in yeast genetics and molecular biology and to be interested in extensive live imaging by fluorescence microscopy and in super-resolution methods.
 +
Publications in the area of research:
 +
Tatiana S. Karpova, Teresa Y. Chen, Brian L. Sprague, James G. McNally. Dynamic interactions of a transcription factor with DNA are accelerated  by a chromatin remodeler.  EMBO Reports. 5: 1064-1070, 2004
 +
Tatiana S. Karpova, Min J. Kim, Corentin Spriet,  Kip Nalley,  Tim Stasevich,  Zoulika Kherrouche, Laurent Heliot, and James G. McNally. Concurrent Fast and Slow Cycling of a Transcriptional Activator at an Endogenous Promoter. Science 319: 466-469, 2008
 +
Applicants should contact Dr. Tatiana Karpova (karpovat@mail.nih.gov) and submit their CV.
  
Application due 6/1/12 for a foreign postdoctoral position at the RIKEN Advance Science Institute, Wako, Japan to work with yeast chemical genomics systems to characterize the targets of novel natural products from a large compound library using a diverse set of genomic and biochemical tools. The position is renewable for 3 years, and details can be found here: http://www.riken.jp/fpr/ Salary 487,000JPY per month. The successful candidate will work with the Molecular Ligand Target research team, headed by Dr. Charlie Boone within the lab of Dr. Minoru Yoshida. http://www.asi.riken.jp/en/laboratories/departments/cbd/chemical/ml-targ/index.html
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=='''Opening for two postdoctoral positions in the Cell Signaling Research Group, UPF, Barcelona, Spain (posted April 2014)'''==
  
For more information please contact Dr. Jeff Piotrowski j.piotrowski@riken.jp or Dr. Charlie Boone charlie.boone@utoronto.ca
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Post description:
 +
We offer two postdoctoral research positions in the Cell Signaling Research Group led by Dr. Francesc Posas and Dr. Eulàlia de Nadal), at the Pompeu Fabra University, Barcelona, Spain.
 +
The main objective of our group is the study of the molecular mechanisms of signal transduction mediated by SAPKs (Stress Activated Protein Kinases) in yeast cells, as well as to understand the complexity of adaptive responses generated by these enzymes. Regulation of gene expression and cell cycle are two of the most important aspects for cell adaptation to stress [Nadal-Ribelles M. et al, Mol Cell (2014); Duch A. et al, Nature (2013); Nadal-Ribelles M. et al, Genome Biol (2012); de Nadal E. and Posas F., Nat. Rev. Genet. (2011); Solé C. et al., EMBO J (2011); Regot S. et al., Nature (2011)].
 +
We are looking for a highly motivated research scientist with consolidated experience in biochemistry and/or yeast genetics to work in these fields.
  
=='''Bioinformatician at St Andrews University'''==
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The Institute:
Bioinformatician - CD1173
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UPF is a young, public and modern university and called to become one of the leading European universities. Awarded with a CEI label (International Excellence Campus) by the Spanish Ministry of Education, UPF's indicators have made it a benchmark for the Spanish and European university systems.
 +
Our group is integrated into the Biomedical Research Park of Barcelona (PRBB), one of the largest hubs of biomedical research in southern Europe.
  
Description:
+
For more information please visit the web site:
School of Medicine, £30,122 - £35,938 pa, Start: As soon as possible,
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http://www.upf.edu/cellsignaling
Fixed-Term for 3 years in the first instance
 
  
Details:
 
An exciting opportunity for a Bioinformatician is available at the School
 
of Medicine at St Andrews University. You will join a dynamic and
 
multidisciplinary community and will play a key role in providing
 
specialist support to diverse projects across different research areas.
 
You will contribute to the development of a next generation sequence
 
analysis service to analyse and interpret data from deep sequencing
 
projects. Alongside provision of high quality support, a significant
 
contribution is expected towards the expansion of the service in scope and
 
staffing by increasing the number of users and attracting external funding.
 
  
You will have a degree in bio-computing, preferably to PhD level with
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=='''Postdoctoral position in Cell Biology, Univ. of Miami, Florida (posted April 2014)'''==
significant experience in bioinformatics. Advanced scripting and
 
experience in the analysis of genome scale biological datasets,
 
particularly high throughput sequencing data are required. We also
 
envisage a role in the installation/maintenance of bioinformatics
 
applications and provision of advice/training to users. Good
 
communications and management skills together with a clear vision of the
 
advances and progress in the field are essential.
 
  
The post will be available immediately for three years in first instance
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A Postdoctoral position is available in the lab of Dr. Sandra Lemmon, University of Miami, Miller School of Medicine. Research focuses on regulation of membrane dynamics in the yeast S. cerevisiae.  Particular interests include the role of phosphorylation, the actin cytoskeleton, and lipids in endocytosis and the function of clathrin in endocytosis and sorting to the lysosome/vacuole. For information on research interests check: <http://biomed.miami.edu/?p=482&pid=208&m=facultyph&mid=0&item=9>. 
and will be based at the School of Medicine.
 
  
Informal enquiries to Dr Silvia Paracchini, e-mail: sp58@st-andrews.ac.uk
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Qualifications:  Candidates should have a PhD in chemistry, biology, genetics or a related life science.  Applicants with a background in cell biology, yeast genetics and molecular biology, fluorescence microscopy and/or lipid biochemistry are especially encouraged to apply. Please submit a curriculum vitae, publications, summary of past research experiences, research interests, and the names of three references to: Dr. Sandra Lemmon at <slemmon[at]miami[dot]edu>.
  
Details and application via:
 
https://www.vacancies.st-andrews.ac.uk/welcome.aspx
 
  
Ref No: CD1173
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=='''Postdoctoral Fellowship in yeast evolutionary genomics at Stanford University''', March 2014==
  
Closing Date: 27 June 2012
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The Fraser Lab in the Department of Biology is seeking a postdoctoral fellow to work on the evolution of gene expression in Saccharomyces yeast.  The exact subject is flexible, but will likely involve using RNA-seq to answer fundamental questions about the mechanisms and consequences of gene expression evolution- especially in cases of evolutionary adaptations.  The ideal candidate would have experience in yeast molecular biology techniques, as well as some familiarity with computational and/or evolutionary analysis.  Salary and benefits are both above the NIH standards for postdocs.  Please email a cover letter and CV to hbfraser[at]stanford[dot]edu.
  
=='''Laboratory Manager in Molecular Biology at Brown University'''==
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=='''Research Associate position (Ph.D. level) at Stanford University''', March 2014==
March 2012: Position available in the laboratory of Tricia Serio, Department of Molecular Biology, Cell Biology, and Biochemistry,  Brown University, Providence, RI
 
  
The Laboratory Manager will have primary responsibility for managing the daily operation of the laboratory and for designing, conducting, and analyzing  experiments to investigate cellular control of prion propagation in the yeast S. cerevisiae. The Laboratory Manager will also oversee and coordinate the activities of other laboratory personnel and the move of our laboratory to the Department of Molecular and Cell Biology, University of Arizona, Tucson, AZ during the summer of 2012. The position will continue at the UA.
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The Fraser Lab in the Department of Biology is seeking a Basic Life Science Research Associate (Ph.D. level). We apply the exciting tools of genomics and high-throughput sequencing to study the evolution of gene expression in a variety of species, but primarily budding yeast. Duties will include:
  
Position requirements:
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Performing a wide range of experiments with the yeast S. cerevisiae. These will focus on a revolutionary new tool in molecular biology: genetic engineering via the CRISPR/Cas system. Other experiments will include gene knockout/replacement, chromatin immunoprecipitation, and high-throughput sequencing of mRNA.
MA, MS, or PhD in molecular biology, genetics, cell biology, biochemistry or related field
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Teaching experimental protocols to others in the lab
• 3-5 years full-time laboratory experience
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Keeping the lab's yeast strains/chemicals organized
Competence in laboratory techniques such as DNA isolation and cloning, PCR, RNA isolation, RT-PCR, protein isolation/purification, gel electrophoresis, western blotting, immunoprecipitation, fluorescence imaging and quantitative microscopy techniques including FRAP and FLIP); experience with yeast preferred but not required
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Overseeing an undergraduate student for dishwashing/media preparation
Excellent organizational/record-keeping skills
 
Excellent hand/eye coordination
 
• Excellent interpersonal skills
 
• Competence with computer programs such as FileMaker, Microsoft Word and Excel, Adobe Photoshop and Illustrator
 
• Excellent quantitative skills
 
• Self-motivated
 
  
Applications should be submitted through Human Resources at Brown University:
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A Ph.D. in a Biology-related field is required, with at least 2 years spent working with S. cerevisiae. Also desirable (but not required) is experience with: mammalian cell culture, chromatin immunoprecipitation, and/or high-throughput sequencing. Please email a cover letter and CV to hbfraser[at]stanford[dot]edu.
https://careers.brown.edu/applicants/jsp/shared/frameset/Frameset.jsp?time=1332257367295
 
position # M02626
 
  
=='''PhD student in Molecular Biology (Marie Curie Early Stage Researcher)at the University of Gothenburg, Sweden'''==
 
A PhD student position in Molecular Biology/Systems Biology is available in the lab of Prof. Stefan Hohmann, Dept of Cell and Molecular Biology, University of Gothenburg, Sweden.
 
  
The research project “Experimental investigation of the yeast Hxk2/Snf1/Mig1 network” aims to understand the dynamic control of the Hxk2/Snf1/Mig1 glucose signalling pathway employing single cell technology developed in the ISOLATE project. Here the experimental platform generated in the project will be optimized, especially the formation of cell arrays of synchronized cells as well as image analysis. Using in parallel Mig1 and Msn2 reporters, response thresholds under different glucose levels will be establish and effects on cell-to-cell variability and bistability will be determined.
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=='''Postdoctoral fellowship in cell cycle evolution at the Institute of Genetics and Development of Rennes, France''', January 2014==
  
Requested Background(advantageous but not required): Yeast biology, yeast genetics, glucose signalling, use of microfluidic devices, microscopy, image analysis, application of nano-sensor technology, ‘systems’ thinking.
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A three-year post-doctoral position supported by a starting grant from the European Research Council (ERC) is available in the group of Dr. Damien Coudreuse at the Institute of Genetics and Development of Rennes (IGDR), France (http://igdr.univ-rennes1.fr/english/). Research in this laboratory takes a synthetic biology approach in fission yeast to study the architecture and evolution of cell cycle regulation. The proposed project aims at understanding fundamental aspects of the evolution of cell proliferation, from how cells overcome external challenges to common features of independent evolutionary processes. It will be based on the use of fission yeast cells operating with various minimal cell cycle control circuits as starting points for experimental evolution approaches. Candidates should contact Dr. Damien Coudreuse at damien.coudreuse@univ-rennes1.fr and send a Curriculum Vitae, including past research experiences and publication records, as well as a letter detailing their motivation and interest in our work. Applicants should also request recommendation letters to be directly sent by two or three references.
 
 
The Marie Curie project ISOLATE is a collaborative research and training network between eight partners, incl. in different European countries. The PhD students and postdocs in the project will perform top-notch research and will additionally benefit from an excellent training network offered by the project partners. Research stays during the PhD projects in other partners’ labs are strongly encouraged. Primarily recruitment of researchers from EC Member States and associated countries, but also open to researchers from third countries. Researchers are normally required to move from one country to another when taking up the appointment.
 
 
 
Please send an application including (1) a max. one-page cover letter containing a justification why this position was chosen as well as a career vision statement, (2) a complete CV with details on education, previous research activities and a list of publications (if any,)(3) a copy of the passport or ID with picture, (4) two letters of recommendation, to maria.enge@gu.se (Project Manager in Prof. Hohmann's group).
 
 
 
=='''PhD student in Systems Biology (Marie Curie Early Stage Researcher)at the University of Gothenburg, Sweden'''==
 
 
 
A PhD student position in Systems Biology is available in the lab of Prof. Stefan Hohmann, Dept of Cell and Molecular Biology, University of Gothenburg, Sweden.
 
 
 
The research project “Theoretical investigation of the yeast Hxk2/Snf1/Mig1 network” aims to understand the dynamic control of the Hxk2/Snf1/Mig1 glucose signalling pathway employing single cell technology developed in the ISOLATE project. Data generated in the project will be interpreted by mathematical modelling together with other project partners to understand feedback and feed-forward mechanisms of signalling. Mutants and inhibitory compounds will be used to test how those affect thresholds and bistability. The analysis will reveal the genetic determination of the system properties, how they are regulated and how robustness against perturbation is established.
 
 
 
Requested Background(advantageous but not required): Yeast biology, yeast genetics, glucose signaling, microscopy, image analysis, development of mathematical models, ‘systems’ thinking.
 
 
 
The Marie Curie project ISOLATE is a collaborative research and training network between eight partners, incl. in different European countries. The PhD students and postdocs in the project will perform top-notch research and will additionally benefit from an excellent training network offered by the project partners. Research stays during the PhD projects in other partners’ labs are strongly encouraged. Primarily recruitment of researchers from EC Member States and associated countries, but also open to researchers from third countries. Researchers are normally required to move from one country to another when taking up the appointment.
 
 
 
Please send an application including (1) a max. one-page cover letter containing a justification why this position was chosen as well as a career vision statement, (2) a complete CV with details on education, previous research activities and a list of publications (if any,)(3) a copy of the passport or ID with picture, (4) two letters of recommendation, to maria.enge@gu.se (Project Manager in Prof. Hohmann's group).
 
 
 
=='''Postdoctoral position to study Ty1 retrotransposition at the University of Georgia''' ==
 
 
 
A postdoctoral position is available in the lab of David J. Garfinkel, Department of Biochemistry and Molecular Biology, University of Georgia, Athens GA to work on the retrovirus-like transposon Ty1 of ''Saccharomyces''. Specifically, we are investigating a new form of RNA-interference based on Ty1 antisense RNAs that acts posttranslationally and targets Ty1 proteins in the absence of the conserved RNAi pathways.
 
 
 
Experience in molecular genetics, protein/nucleic acid interactions or cytology would be helpful.
 
 
 
Also see our website for further information [http://www.bmb.uga.edu/home/people/people.php?fname=David&lname=Garfinkel]
 
 
 
 
 
Please send resume or inquiries to:
 
 
 
David J. Garfinkel
 
 
 
Department of Biochemistry and Molecular Biology
 
 
 
A130 Life Sciences
 
 
 
120 Green St.
 
 
 
University of Georgia
 
 
 
Athens, GA 30622
 
 
 
 
 
tel: 706-542-9403
 
 
 
djgarf@bmb.uga.edu
 
 
 
==Yeast Systems Biology Position at Virginia Tech (Research Associate or Sr Research Associate)==
 
The Synthetic Biology group at Virginia Bioinformatics Institute (VBI) is involved in two collaborative research projects focused on the development of mathematical models of gene-protein regulatory networks controlling cell growth and division. Temporal organization of the budding yeast cell cycle has been studied from two vantage points: bottom-up models emphasize a protein regulatory network centered around cyclin-dependent protein kinases, whereas top-down models focus on a gene regulatory network governed by interrelated transcription factors. The first project is focused on unifying these two perspectives. The second project is focused on the development of stochastic models of the regulatory network controlling the cell cycle. Both projects are performed in close collaboration with experts in computer science, data mining, bioinformatics, and mathematical modeling. The successful candidate will be expected to contribute significantly to these two projects by being responsible for designing and performing experiments used to validate model predictions. These experiments will involve the development of a new collection of cell cycle mutants and their quantitative characterization by time-lapse microscopy. In addition, the successful candidate will be expected to prepare the results for publication and presentation, to help supervise graduate and undergraduate students, and to contribute to grant proposals.
 
 
 
Dependent on the qualifications of the successful candidate, the position will hold the research faculty rank of either Research Associate or Senior Research Associate.
 
 
 
Go to the [http://bit.ly/n4nDUQ position description] for additional information and for submitting applications.
 
 
 
More information about our team can be found by visiting:
 
* [http://www.vbi.vt.edu/faculty/personal/Jean_Peccoud Jean Peccoud's home page]
 
* [http://www.biol.vt.edu/faculty/tyson/ John Tyson's home page]
 
* [https://bioinformatics.cs.vt.edu/~murali/ T.M. Murali's home page]
 
 
 
==Postdoctoral grants at the Max Planck Institute for Evolutionary Biology, Plön, Germany==
 
Post-doctoral grants are available for ambitious, motivated scientists to join Experimental Evolution Research Group. We can provide excellent research funding and support for projects that build on or complement our existing program. Positions are funded by the Max Planck Society for 2 years initially.
 
 
 
We use Saccharomyces yeasts as model organisms for evolution and ecology.  ­ ''Saccharomyces cerevisiae'' is probably the best known and most tractable model organism used in biology, but its life outside the laboratory is poorly understood. We study the evolution of various interesting yeast traits using both laboratory experiments and observations of wild yeast. For a primer on yeast evolutionary biology, and to understand the motivation for our research please read Greig, D. & Leu, J-Y. (2009) “Natural history of budding yeast” Curr. Biol. 19:R886-890.  For our current work, please see our [http://www.evolbio.mpg.de/expevolution/Greig/Welcome.html lab web page]
 
 
 
The Max Planck Institute for Evolutionary Biology offers outstanding infrastructure and facilities, and is attractively located in Northern Germany, in a lake district near the Baltic coast. It is well connected by train to the university towns of Lübeck and Kiel, and Hamburg is the nearest major airport.
 
 
Applicants must have a PhD and at least one peer-reviewed publication in the field of evolution, ecology, or yeast genetics. Applicants should prepare a short (<500 word) research proposal, a CV, and contact details for three academic referees. They should combine these into a single PDF file and send it by email to Duncan Greig (d.greig@evolbio.mpg.de). Informal enquiries can be made to any member of the Research Group. Applications will be considered until suitable candidates are found. September 2011
 
 
 
==Postdoctoral position==
 
SEPTEMBER 2011: A postdoctoral position is available in the laboratory of Claudio Joazeiro, Department of Cell Biology, The Scripps Research Institute (San Diego, California).
 
 
 
Research in the laboratory addresses the function of E3 ubiquitin ligases in biology and disease.
 
 
 
The position available is to elucidate the functions and mechanisms of the E3 ligase LISTERIN. We had previously reported on a new mouse model of neurodegeneration caused by mutation of Listerin/Ltn1, a novel E3 (Chu et al. 2009). Homozygous mutant mice exhibit profound early-onset and progressive neurological and motor dysfunction. The focus of our most recent work has been on elucidating this E3’s critical biological role(s) and determining how defects in its function lead to the disease. Listerin/Ltn1 is conserved in all eukaryotes, so we have taken advantage of budding yeast and found that the E3 is ribosome-associated and functions in the quality control of a specific subset of aberrant, nascent proteins (Bengtson & Joazeiro 2010). Currently, we undertake biochemistry, yeast genetics, mammalian tissue culture and genomic approaches to continue our characterization of Listerin/Ltn1, and are positioned to readily test the relevance of the discoveries we make for neurodegeneration using the mouse model. There are opportunities for studies along any of the above research lines, depending on the background and interests of the applicant.
 
 
 
Selected references:
 
*Bengtson MH & Joazeiro CA. 2010. Role of a ribosome-associated E3 ubiquitin ligase in protein quality control. Nature 467:470-3.
 
*Deshaies RJ & Joazeiro CA. 2009. RING domain E3 ubiquitin ligases. Annu Rev Biochem. 78:399-434.
 
*Chu J et al. 2009. A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration. PNAS 106:2097-103.
 
 
 
The candidate should be independent, hard working, proactive and productive, and should have strong conceptual and experimental background in biochemistry and molecular biology.
 
 
Please send CV, a 1-page statement of current and future research interests, and the names and contact information of three references to:<br>
 
Claudio Joazeiro<br>
 
c/o Miriam Berba (Email: mirberba@scripps.edu)<br>
 
The Scripps Research Institute, CB-163<br>
 
10550 N Torrey Pines Rd<br>
 
La Jolla, CA  92037 USA
 
 
 
==Postdoctoral position - Laboratory of Cell Physics - Strasbourg, France==
 
Postdoctoral position is available in the Laboratory of Cell Physics, ISIS/IGBMC, Strasbourg, France. The project will focus on the dynamics of the cytokinetic ring in the fission yeast S. pombe. The roles of the Rho GTPase, actin polymerisation, and myosin will be studied. The work will involve genetics, cell biology, microscopy, microfabrication and microfluidics; for more information, send a CV and contact information of referees to Dr. Daniel Riveline (riveline@unistra.fr)
 

Revision as of 16:25, 21 July 2014

Technician/Research assistant position available

A 3-year technician/research assistant position is available in the group of Dr. Damien Coudreuse (www.synthecell.org) at the Institute of Genetics and Development of Rennes (IGDR), France (http://igdr.univ-rennes1.fr/english/). Research in this laboratory takes a synthetic biology approach in fission yeast to study the architecture and evolution of cell cycle regulation. Routinely used techniques in the team include fission yeast genetics, molecular biology (DNA, RNA and protein biology) and microscopy. The role of the technician/engineer will be to provide help with such techniques to various members of the team as well as to take responsibility for a number of common tasks in the laboratory.Candidates should contact Dr. Damien Coudreuse at damien.coudreuse@univ-rennes1.fr and send a Curriculum Vitae, including past experiences, as well as a letter detailing their motivation and interest in the position. Applicants should also request recommendation letters to be directly sent by one to three references.


Post-doctoral positions available - Complexity and Variability in Cell Proliferation

Two three-year post-doctoral positions supported by a starting grant from the European Research Council (ERC) are available in the group of Dr. Damien Coudreuse (www.synthecell.org) at the Institute of Genetics and Development of Rennes (IGDR), France (http://igdr.univ-rennes1.fr/english/). Research in this laboratory takes a synthetic biology approach in fission yeast to study the architecture and evolution of cell cycle regulation. The proposed projects aim at understanding fundamental aspects of the control of cell proliferation, from the buffering of variability in the different mechanisms driving cell cycle progression to the evolution of complexity in cell cycle control.Candidates should contact Dr. Damien Coudreuse at damien.coudreuse@univ-rennes1.fr and send a Curriculum Vitae, including past research experiences and publication records, as well as a letter detailing their motivation and interest in our work. Applicants should also request recommendation letters to be directly sent by two or three references.


POSTDOCTORAL POSITION - NIH, National Cancer Institute, Posted April 16, 2014

A postdoctoral position is available within the Optical Imaging Core of the Laboratory of Receptor Biology and Gene Expression (NCI/NIH) to conduct research in the regulation of transcription in Saccharomyces cerevisiae. The candidate is expected to have a background in yeast genetics and molecular biology and to be interested in extensive live imaging by fluorescence microscopy and in super-resolution methods. Publications in the area of research: Tatiana S. Karpova, Teresa Y. Chen, Brian L. Sprague, James G. McNally. Dynamic interactions of a transcription factor with DNA are accelerated by a chromatin remodeler. EMBO Reports. 5: 1064-1070, 2004 Tatiana S. Karpova, Min J. Kim, Corentin Spriet, Kip Nalley, Tim Stasevich, Zoulika Kherrouche, Laurent Heliot, and James G. McNally. Concurrent Fast and Slow Cycling of a Transcriptional Activator at an Endogenous Promoter. Science 319: 466-469, 2008 Applicants should contact Dr. Tatiana Karpova (karpovat@mail.nih.gov) and submit their CV.

Opening for two postdoctoral positions in the Cell Signaling Research Group, UPF, Barcelona, Spain (posted April 2014)

Post description: We offer two postdoctoral research positions in the Cell Signaling Research Group led by Dr. Francesc Posas and Dr. Eulàlia de Nadal), at the Pompeu Fabra University, Barcelona, Spain. The main objective of our group is the study of the molecular mechanisms of signal transduction mediated by SAPKs (Stress Activated Protein Kinases) in yeast cells, as well as to understand the complexity of adaptive responses generated by these enzymes. Regulation of gene expression and cell cycle are two of the most important aspects for cell adaptation to stress [Nadal-Ribelles M. et al, Mol Cell (2014); Duch A. et al, Nature (2013); Nadal-Ribelles M. et al, Genome Biol (2012); de Nadal E. and Posas F., Nat. Rev. Genet. (2011); Solé C. et al., EMBO J (2011); Regot S. et al., Nature (2011)]. We are looking for a highly motivated research scientist with consolidated experience in biochemistry and/or yeast genetics to work in these fields.

The Institute: UPF is a young, public and modern university and called to become one of the leading European universities. Awarded with a CEI label (International Excellence Campus) by the Spanish Ministry of Education, UPF's indicators have made it a benchmark for the Spanish and European university systems. Our group is integrated into the Biomedical Research Park of Barcelona (PRBB), one of the largest hubs of biomedical research in southern Europe.

For more information please visit the web site: http://www.upf.edu/cellsignaling


Postdoctoral position in Cell Biology, Univ. of Miami, Florida (posted April 2014)

A Postdoctoral position is available in the lab of Dr. Sandra Lemmon, University of Miami, Miller School of Medicine. Research focuses on regulation of membrane dynamics in the yeast S. cerevisiae. Particular interests include the role of phosphorylation, the actin cytoskeleton, and lipids in endocytosis and the function of clathrin in endocytosis and sorting to the lysosome/vacuole. For information on research interests check: <http://biomed.miami.edu/?p=482&pid=208&m=facultyph&mid=0&item=9>.

Qualifications: Candidates should have a PhD in chemistry, biology, genetics or a related life science. Applicants with a background in cell biology, yeast genetics and molecular biology, fluorescence microscopy and/or lipid biochemistry are especially encouraged to apply. Please submit a curriculum vitae, publications, summary of past research experiences, research interests, and the names of three references to: Dr. Sandra Lemmon at <slemmon[at]miami[dot]edu>.


Postdoctoral Fellowship in yeast evolutionary genomics at Stanford University, March 2014

The Fraser Lab in the Department of Biology is seeking a postdoctoral fellow to work on the evolution of gene expression in Saccharomyces yeast. The exact subject is flexible, but will likely involve using RNA-seq to answer fundamental questions about the mechanisms and consequences of gene expression evolution- especially in cases of evolutionary adaptations. The ideal candidate would have experience in yeast molecular biology techniques, as well as some familiarity with computational and/or evolutionary analysis. Salary and benefits are both above the NIH standards for postdocs. Please email a cover letter and CV to hbfraser[at]stanford[dot]edu.

Research Associate position (Ph.D. level) at Stanford University, March 2014

The Fraser Lab in the Department of Biology is seeking a Basic Life Science Research Associate (Ph.D. level). We apply the exciting tools of genomics and high-throughput sequencing to study the evolution of gene expression in a variety of species, but primarily budding yeast. Duties will include:

• Performing a wide range of experiments with the yeast S. cerevisiae. These will focus on a revolutionary new tool in molecular biology: genetic engineering via the CRISPR/Cas system. Other experiments will include gene knockout/replacement, chromatin immunoprecipitation, and high-throughput sequencing of mRNA. • Teaching experimental protocols to others in the lab • Keeping the lab's yeast strains/chemicals organized • Overseeing an undergraduate student for dishwashing/media preparation

A Ph.D. in a Biology-related field is required, with at least 2 years spent working with S. cerevisiae. Also desirable (but not required) is experience with: mammalian cell culture, chromatin immunoprecipitation, and/or high-throughput sequencing. Please email a cover letter and CV to hbfraser[at]stanford[dot]edu.


Postdoctoral fellowship in cell cycle evolution at the Institute of Genetics and Development of Rennes, France, January 2014

A three-year post-doctoral position supported by a starting grant from the European Research Council (ERC) is available in the group of Dr. Damien Coudreuse at the Institute of Genetics and Development of Rennes (IGDR), France (http://igdr.univ-rennes1.fr/english/). Research in this laboratory takes a synthetic biology approach in fission yeast to study the architecture and evolution of cell cycle regulation. The proposed project aims at understanding fundamental aspects of the evolution of cell proliferation, from how cells overcome external challenges to common features of independent evolutionary processes. It will be based on the use of fission yeast cells operating with various minimal cell cycle control circuits as starting points for experimental evolution approaches. Candidates should contact Dr. Damien Coudreuse at damien.coudreuse@univ-rennes1.fr and send a Curriculum Vitae, including past research experiences and publication records, as well as a letter detailing their motivation and interest in our work. Applicants should also request recommendation letters to be directly sent by two or three references.