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=='''Postdoctoral Position in Chemical Genomics at RIKEN Advance Science Institute, Tokyo, Japan'''==
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=='''Postdoctoral position in Cell Biology, Univ. of Miami, Florida (posted April 2014)'''==
  
We are accepting applications for a postdoctoral position at the RIKEN Advance Science Institute to work with yeast chemical genomics systems to characterize the targets of novel natural products from a large compound library using a diverse set of genomic and biochemical tools. The position is for a minimum of 1 year starting 4/2013 and renewable.  
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A Postdoctoral position is available in the lab of Dr. Sandra Lemmon, University of Miami, Miller School of Medicine.  Research focuses on regulation of membrane dynamics in the yeast S. cerevisiae.  Particular interests include the role of phosphorylation, the actin cytoskeleton, and lipids in endocytosis and the function of clathrin in endocytosis and sorting to the lysosome/vacuole. For information on research interests check: <http://biomed.miami.edu/?p=482&pid=208&m=facultyph&mid=0&item=9>.   
Details on the research team can be found here: http://www.riken.jp/ChemicalGenomics/Target_E.htmlSalary is competitive with benefits. The successful candidate will work with the Molecular Ligand Target research team, headed by Dr. Charlie Boone within the Chemical Biology Department of Dr. Hiroyuki Osada. For more information please contact Dr. Jeff Piotrowski (j.piotrowski_at_riken.jp) or Dr. Charlie Boone (charlie.boone_at_utoronto.ca) for more details
 
  
 +
Qualifications:  Candidates should have a PhD in chemistry, biology, genetics or a related life science.  Applicants with a background in cell biology, yeast genetics and molecular biology, fluorescence microscopy and/or lipid biochemistry are especially encouraged to apply. Please submit a curriculum vitae, publications, summary of past research experiences, research interests, and the names of three references to:  Dr. Sandra Lemmon at <slemmon[at]miami[dot]edu>.
  
=='''2-year postdoctoral position at the Institute of Genetics and Development of Rennes (IGDR), France'''==
 
  
A 2-year postdoctoral position is open in the newly established team of Gwenaël Rabut at the Institute of Genetics and Development of Rennes (IGDR), France (http://igdr.univ-rennes1.fr/english/). Our team investigates the molecular functions of ubiquitin and ubiquitin-like protein modifiers, particularly focusing on the regulation of nuclear processes such as DNA replication and DNA repair. We are studying these functions in budding yeast, using a combination of complimentary biochemical and genetic approaches as well as advanced light microscopy and mass spectrometry.
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=='''Postdoctoral Fellowship in yeast evolutionary genomics at Stanford University'''==
  
We are seeking highly motivated candidates with a strong background in molecular biology and biochemistry. Those experienced in mass spectrometry or genetics are encouraged to apply. We also welcome applicants with expertise in advanced light microscopy or multidisciplinary approaches.
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The Fraser Lab in the Department of Biology is seeking a postdoctoral fellow to work on the evolution of gene expression in Saccharomyces yeast.  The exact subject is flexible, but will likely involve using RNA-seq to answer fundamental questions about the mechanisms and consequences of gene expression evolution- especially in cases of evolutionary adaptations.  The ideal candidate would have experience in yeast molecular biology techniques, as well as some familiarity with computational and/or evolutionary analysis. Salary and benefits are both above the NIH standards for postdocs.  Please email a cover letter and CV to hbfraser[at]stanford[dot]edu.
  
The Institute of Genetics and Development of Rennes is dynamic and expanding, with 20 senior and junior groups addressing a wide range of subjects in cell biology in a multidisciplinary environment. It benefits from excellent core facilities, such as state-of-the-art microscopy and genomics centers.
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=='''Research Associate position (Ph.D. level) at Stanford University'''==
  
Rennes is a lively city located in the North-West of France, with fast and direct access to Paris (2 hours by train). Its rich student life, its strong music and food heritage and its proximity to the coast make it a very welcoming and pleasant place to live.
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The Fraser Lab in the Department of Biology is seeking a Basic Life Science Research Associate (Ph.D. level). We apply the exciting tools of genomics and high-throughput sequencing to study the evolution of gene expression in a variety of species, but primarily budding yeast. Duties will include:
  
Candidates should send their CV and a letter of motivation to Gwenaël Rabut (gwenael.rabut@inserm.fr) and provide the name and contact details of at least two references.
+
• Performing a wide range of experiments with the yeast S. cerevisiae. These will focus on a revolutionary new tool in molecular biology: genetic engineering via the CRISPR/Cas system. Other experiments will include gene knockout/replacement, chromatin immunoprecipitation, and high-throughput sequencing of mRNA.
 +
• Teaching experimental protocols to others in the lab
 +
• Keeping the lab's yeast strains/chemicals organized
 +
• Overseeing an undergraduate student for dishwashing/media preparation
  
 +
A Ph.D. in a Biology-related field is required, with at least 2 years spent working with S. cerevisiae. Also desirable (but not required) is experience with: mammalian cell culture, chromatin immunoprecipitation, and/or high-throughput sequencing.  Please email a cover letter and CV to hbfraser[at]stanford[dot]edu.
  
=='''Post-doctoral Research Associate in Cell Biology at University of Tennessee at Knoxville'''==
 
  
A post-doctoral fellow position is available starting January 2013 in the lab of Dr. Maitreyi Das,
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=='''Postdoctoral fellowship in cell cycle evolution at the Institute of Genetics and Development of Rennes, France'''==
Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville.
 
Research in this lab is focused on cell polarity using fission yeast (S. pombe) as a model organism. The
 
project will involve understanding fundamental processes that regulate polarized cell growth, especially
 
higher-order molecular networks that are controlled both spatially and temporally. To achieve this
 
single-cell systems biology with a combination of experimental and quantitative imaging approaches will
 
be used. For more details please see the following link,
 
http://web.bio.utk.edu/bcmb/faculty/Individual_Faculty_Pages/Das_Maitreyi/Das_Maitreyi.html.
 
Qualifications:
 
Candidate should have a PhD degree. Major techniques required for the success of this project are yeast
 
cell biology and microscopy. An ideal candidate should have expertise in all or any of these techniques.
 
Motivated candidates should submit their updated curriculum vitae including past research experience
 
and list of publications, a statement of research interests, and the contact information for at least 3
 
references to mdas@utk.edu.
 
  
=='''1 Year Technician Position in Yeast Lab at the MRC National Institute for Medical Research in London'''==
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A three-year post-doctoral position supported by a starting grant from the European Research Council (ERC) is available in the group of Dr. Damien Coudreuse at the Institute of Genetics and Development of Rennes (IGDR), France (http://igdr.univ-rennes1.fr/english/). Research in this laboratory takes a synthetic biology approach in fission yeast to study the architecture and evolution of cell cycle regulation. The proposed project aims at understanding fundamental aspects of the evolution of cell proliferation, from how cells overcome external challenges to common features of independent evolutionary processes. It will be based on the use of fission yeast cells operating with various minimal cell cycle control circuits as starting points for experimental evolution approaches. Candidates should contact Dr. Damien Coudreuse at damien.coudreuse@univ-rennes1.fr and send a Curriculum Vitae, including past research experiences and publication records, as well as a letter detailing their motivation and interest in our work. Applicants should also request recommendation letters to be directly sent by two or three references.
  
We are looking to recruit a Research Technician to work in the research group of Peter Thorpe in the Division of Stem Cell Biology.
 
http://www.nimr.mrc.ac.uk/research/peter-thorpe/
 
  
As a Research Technician you will possess a degree or equivalent in chemistry, biology, or biotechnologies, have prior laboratory experience and potentially some experience working with yeast.
+
=='''Postdoctoral Fellowship in Cell Fate and Gene Regulation (POS00123), LRI/Crick Institute, London, UK'''==
  
Along with a confidence with basic molecular biology and computational data analysis you should be able to plan your work efficiently to meet deadlines and be meticulous in keeping accurate records. You will be expected to prepare and present your results both in written form and orally. You will have good communication skills and will be expected to integrate into a team, working closely with your colleagues.
+
We seek a talented and motivated Postdoc to join the Cell Fate and Gene Regulation Laboratory in London, UK. The Cell Fate and Gene Regulation laboratory headed by Dr Folkert van Werven will be opened in the fall of this year. It will be a small, highly interactive, international research group that focuses on understanding the molecular mechanisms of how cell fate decisions are controlled. Initially we will use budding yeast as a model system, and take molecular, systematic and quantitative approaches (including single-molecule, proteomic, and genomic techniques) to study this problem. For more information please send an email (Folkert.vanWerven at cancer.org.uk) or go to:
 +
https://cruk.taleo.net/careersection/cruk_corporate/jobdetail.ftl?lang=en&job=POS00123&view=rss
  
You will be confident using standard computer software, including Microsoft office and you may have experience handling large datasets. Specialist training to support the development of skills will be given where necessary.
 
For more details see
 
http://www.nature.com/naturejobs/science/jobs/282634-Research-Technician-1-year-fixed-term
 
 
Applications are handled by the RCUK Shared Services Centre; to apply please visit our job board at http://www.topcareer.jobs/Vacancy/irc65811_2224.aspx. If you are unable to apply online please contact us on 01793 867003 quoting reference IRC65811.
 
 
Closing date: 28th September 2012
 
  
 
=='''Postdoctoral Position in Biology of Yeast Colonies at Charles University in Prague, Czech Republic'''==
 
=='''Postdoctoral Position in Biology of Yeast Colonies at Charles University in Prague, Czech Republic'''==
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The applicants should have (i) a recent PhD (the degree obtained no earlier than on 28th of March 2008), (ii) promising publication record and be able to speak fluent English (or Czech). Please send your motivation letter (<500 words), CV, list of publications (including IF and the number of citations) and contact information of three references directly to the group leader Zdena Palkova,  mailto:zdenap@natur.cuni.cz (please combine all documents into single PDF file). Applications will be considered until suitable candidates are found. The positions include additional funds for the international mobility (3 months).
 
The applicants should have (i) a recent PhD (the degree obtained no earlier than on 28th of March 2008), (ii) promising publication record and be able to speak fluent English (or Czech). Please send your motivation letter (<500 words), CV, list of publications (including IF and the number of citations) and contact information of three references directly to the group leader Zdena Palkova,  mailto:zdenap@natur.cuni.cz (please combine all documents into single PDF file). Applications will be considered until suitable candidates are found. The positions include additional funds for the international mobility (3 months).
  
=='''Laboratory Manager in Molecular Biology at Brown University'''==
 
March 2012: Position available in the laboratory of Tricia Serio, Department of Molecular Biology, Cell Biology, and Biochemistry,  Brown University, Providence, RI
 
 
The Laboratory Manager will have primary responsibility for managing the daily operation of the laboratory and for designing, conducting, and analyzing  experiments to investigate cellular control of prion propagation in the yeast S. cerevisiae.  The Laboratory Manager will also oversee and coordinate the activities of other laboratory personnel and the move of our laboratory to the Department of Molecular and Cell Biology, University of Arizona, Tucson, AZ during the summer of 2012.  The position will continue at the UA.
 
 
Position requirements:
 
• MA, MS, or PhD in molecular biology, genetics, cell biology, biochemistry or related field
 
• 3-5 years full-time laboratory experience
 
• Competence in laboratory techniques such as DNA isolation and cloning, PCR, RNA isolation, RT-PCR, protein isolation/purification, gel electrophoresis, western blotting, immunoprecipitation, fluorescence imaging and quantitative microscopy techniques including FRAP and FLIP); experience with yeast preferred but not required
 
• Excellent organizational/record-keeping skills
 
• Excellent hand/eye coordination
 
• Excellent interpersonal skills
 
• Competence with computer programs such as FileMaker, Microsoft Word and Excel, Adobe Photoshop and Illustrator
 
• Excellent quantitative skills
 
• Self-motivated
 
 
Applications should be submitted through Human Resources at Brown University:
 
https://careers.brown.edu/applicants/jsp/shared/frameset/Frameset.jsp?time=1332257367295
 
position # M02626
 
  
 
=='''PhD student in Molecular Biology (Marie Curie Early Stage Researcher)at the University of Gothenburg, Sweden'''==
 
=='''PhD student in Molecular Biology (Marie Curie Early Stage Researcher)at the University of Gothenburg, Sweden'''==
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Also see our website for further information [http://www.bmb.uga.edu/home/people/people.php?fname=David&lname=Garfinkel]
 
Also see our website for further information [http://www.bmb.uga.edu/home/people/people.php?fname=David&lname=Garfinkel]
 
  
 
Please send resume or inquiries to:
 
Please send resume or inquiries to:
 
+
David J. Garfinkel
David J. Garfinkel
+
Department of Biochemistry and Molecular Biology
 
+
A130 Life Sciences
Department of Biochemistry and Molecular Biology
+
120 Green St.
 
+
University of Georgia
A130 Life Sciences
+
Athens, GA 30622
 
+
120 Green St.
+
tel: 706-542-9403
 
+
djgarf@bmb.uga.edu
University of Georgia
 
 
 
Athens, GA 30622
 
 
 
 
 
tel: 706-542-9403
 
 
 
djgarf@bmb.uga.edu
 
  
 
==Yeast Systems Biology Position at Virginia Tech (Research Associate or Sr Research Associate)==
 
==Yeast Systems Biology Position at Virginia Tech (Research Associate or Sr Research Associate)==
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* [https://bioinformatics.cs.vt.edu/~murali/ T.M. Murali's home page]
 
* [https://bioinformatics.cs.vt.edu/~murali/ T.M. Murali's home page]
  
==Postdoctoral grants at the Max Planck Institute for Evolutionary Biology, Plön, Germany==
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==Postdoctoral position - Laboratory of Cell Physics - Strasbourg, France==
Post-doctoral grants are available for ambitious, motivated scientists to join Experimental Evolution Research Group. We can provide excellent research funding and support for projects that build on or complement our existing program. Positions are funded by the Max Planck Society for 2 years initially.  
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Postdoctoral position is available in the Laboratory of Cell Physics, ISIS/IGBMC, Strasbourg, France. The project will focus on the dynamics of the cytokinetic ring in the fission yeast S. pombe. The roles of the Rho GTPase, actin polymerisation, and myosin will be studied. The work will involve genetics, cell biology, microscopy, microfabrication and microfluidics; for more information, send a CV and contact information of referees to Dr. Daniel Riveline (riveline@unistra.fr)
  
We use Saccharomyces yeasts as model organisms for evolution and ecology.  ­ ''Saccharomyces cerevisiae'' is probably the best known and most tractable model organism used in biology, but its life outside the laboratory is poorly understood. We study the evolution of various interesting yeast traits using both laboratory experiments and observations of wild yeast. For a primer on yeast evolutionary biology, and to understand the motivation for our research please read Greig, D. & Leu, J-Y. (2009) “Natural history of budding yeast” Curr. Biol. 19:R886-890.  For our current work, please see our [http://www.evolbio.mpg.de/expevolution/Greig/Welcome.html lab web page]
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==Postdoctoral Position in Quantitative Systems Biology==
 +
A postdoctoral fellow position is immediately available for a highly motivated recent PhD or MD/PhD graduate in biomedical science in the lab of Dr. Gregor Neuert at Vanderbilt University School of Medicine in Nashville, Tennessee.
  
The Max Planck Institute for Evolutionary Biology offers outstanding infrastructure and facilities, and is attractively located in Northern Germany, in a lake district near the Baltic coast. It is well connected by train to the university towns of Lübeck and Kiel, and Hamburg is the nearest major airport.
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The main interests of the group focuses on quantitative understanding of signaling and gene regulatory processes of coding and non-coding RNA in single cells at single molecule resolution. Our research methods include a combination of single-cell experimental and computational techniques as well as molecular biology and yeast genetics.
 
Applicants must have a PhD and at least one peer-reviewed publication in the field of evolution, ecology, or yeast genetics. Applicants should prepare a short (<500 word) research proposal, a CV, and contact details for three academic referees. They should combine these into a single PDF file and send it by email to Duncan Greig (d.greig@evolbio.mpg.de). Informal enquiries can be made to any member of the Research Group. Applications will be considered until suitable candidates are found. September 2011
 
  
==Postdoctoral position==
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We are seeking highly motivated and curious applicants with strong background in yeast genetics, molecular biology and computational biology. Background in microscopy and computational modeling is also considered a plus but not required.  
SEPTEMBER 2011: A postdoctoral position is available in the laboratory of Claudio Joazeiro, Department of Cell Biology, The Scripps Research Institute (San Diego, California).  
 
  
Research in the laboratory addresses the function of E3 ubiquitin ligases in biology and disease.
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We offer a highly interactive, international and interdisciplinary research environment with strong mentoring and career development support. Vanderbilt University School of Medicine is ranked #9 in NIH funding and #15 in U.S. News medical school ranking and is equipped with world-class cutting-edge core facilities.  
 
 
The position available is to elucidate the functions and mechanisms of the E3 ligase LISTERIN. We had previously reported on a new mouse model of neurodegeneration caused by mutation of Listerin/Ltn1, a novel E3 (Chu et al. 2009). Homozygous mutant mice exhibit profound early-onset and progressive neurological and motor dysfunction. The focus of our most recent work has been on elucidating this E3’s critical biological role(s) and determining how defects in its function lead to the disease. Listerin/Ltn1 is conserved in all eukaryotes, so we have taken advantage of budding yeast and found that the E3 is ribosome-associated and functions in the quality control of a specific subset of aberrant, nascent proteins (Bengtson & Joazeiro 2010). Currently, we undertake biochemistry, yeast genetics, mammalian tissue culture and genomic approaches to continue our characterization of Listerin/Ltn1, and are positioned to readily test the relevance of the discoveries we make for neurodegeneration using the mouse model. There are opportunities for studies along any of the above research lines, depending on the background and interests of the applicant.
 
 
 
Selected references:
 
*Bengtson MH & Joazeiro CA. 2010. Role of a ribosome-associated E3 ubiquitin ligase in protein quality control. Nature 467:470-3.
 
*Deshaies RJ & Joazeiro CA. 2009. RING domain E3 ubiquitin ligases. Annu Rev Biochem. 78:399-434.
 
*Chu J et al. 2009. A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration. PNAS 106:2097-103.
 
 
 
The candidate should be independent, hard working, proactive and productive, and should have strong conceptual and experimental background in biochemistry and molecular biology.
 
 
Please send CV, a 1-page statement of current and future research interests, and the names and contact information of three references to:<br>
 
Claudio Joazeiro<br>
 
c/o Miriam Berba (Email: mirberba@scripps.edu)<br>
 
The Scripps Research Institute, CB-163<br>
 
10550 N Torrey Pines Rd<br>
 
La Jolla, CA  92037 USA
 
 
 
==Postdoctoral position - Laboratory of Cell Physics - Strasbourg, France==
 
Postdoctoral position is available in the Laboratory of Cell Physics, ISIS/IGBMC, Strasbourg, France. The project will focus on the dynamics of the cytokinetic ring in the fission yeast S. pombe. The roles of the Rho GTPase, actin polymerisation, and myosin will be studied. The work will involve genetics, cell biology, microscopy, microfabrication and microfluidics; for more information, send a CV and contact information of referees to Dr. Daniel Riveline (riveline@unistra.fr)
 
  
=='''1 one . Postdoctoral  position at Rio de Janeiro, Brazil'''==
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Selected publications:
Laboratory of yeast molecular biology. Mónica Montero Lomelí
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Neuert, Munsky et al. Science 2013 ; Munsky, Neuert et al. Science 2012; Bumgarner, Neuert et al. Mol.Cell 2012; Van Werven, Neuert et al. Cell 2013
Instituto de Bioquimica Medica.Programa de Biologia Molecular e
 
Biotecnologia.Universidade Federal do Rio de Janeiro.Rio de Janerio, Brazil.
 
http://yeastworld.wordpress.com
 
  
Our group is interested in the potential use of Yarrowia lipolytica,  
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Interested applicants should send curriculum vitae, a summary of research experience and accomplishments, and contact information of 2-3 references to gregor.neuert@vanderbilt.edu.
as work-horse for biotechnological applications. The
 
position available is to design a platform for gene deletion and  heterologous
 
expression of proteins in a wild type strain..  We had previously reported a rapid
 
high throughput method to study lipid droplet dynamics in the  known yeast  Saccharomyces cerevisiae 
 
Bozaquel-Morais BL, PLoS One. 2010 Oct 28;5(10):e13692) . The focus of our
 
most recent work is to study the signaling mechanisms that alter the
 
accumulation of lipid droplets in yeast, using S. cerevisiae, Yarrowia
 
lipolytica and Usitlago maydis. We use biochemistry, yeast genetics,
 
microarray and systems biology approaches. Depending on the background and
 
interest of the applicant we offer opportunity to study Yarrowia lipolytica
 
and join the  other research projects. The fellowship is renewable for three
 
years and can start as soon as March 2013. The candidate
 
should be independent, with strong background in biochemistry, yeast genetics
 
and molecular biology, and no more than 5 years of receiving the PhD degree.
 
Please send to montero@bioqmed.ufrj.br, monterolomeli@hotmail.com before
 
January 7, 2013 the following all in a single PDF file:
 
1.    CV
 
2.     one-page motivation letter with your research interests,
 
3.     and the names and contact information of three references
 
  
 +
For more information please visit:
 +
https://www.mc.vanderbilt.edu/root/vumc.php?site=neuertlab
  
=='''Postdoctoral Position Available in Systems Biology at E&J Gallo Winery, Modesto, CA'''==
 
We are accepting applications for a postdoctoral position to work with yeast and grape metabolic systems.  Using a diverse set of computational biology, molecular biology, biochemistry, microbiology and wine fermentation we seek to develop cost-effective, efficient processes that deliver the best quality wine to the consumer.  The successful candidate will work on a cross-functional team using transcriptomics, functional genomics, metabolomics and mathematical modeling to understand and predict the production of specific molecules known to be quality attributes in grape and wine.
 
  
There is science and there is art; at E&J Gallo, the world’s largest and most successful family-owned winery, we have it allIf you are looking for a diverse workplace filled with energy, enthusiasm, innovation and a love for wine then E&J Gallo Winery is the place for youTo learn more about this exciting and unique opportunity to incorporate your scientific skills with state of the art industrial processes please see the following link.
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'''
*[http://hrsjobs.gallo.com/psp/ert/EJGAPP/PSFT_HR/c/HRS_HRAM.HRS_CE.GBL?Page=HRS_CE_JOB_DTL&Action=A&JobOpeningId=6210&SiteId=1&PostingSeq=1]
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== POSTDOCTORAL POSITION - NIH, National Cancer Institute, Posted April 16, 2014 ==
 +
'''
 +
A postdoctoral position is available within the Optical Imaging Core of the Laboratory of Receptor Biology and Gene Expression (NCI/NIH) to conduct research in the regulation of transcription in Saccharomyces cerevisiae. The candidate is expected to have a background in yeast genetics and molecular biology and to be interested in extensive live imaging by fluorescence microscopy and in super-resolution methods.
 +
Publications in the area of research:
 +
Tatiana S. Karpova, Teresa Y. Chen, Brian L. Sprague, James G. McNally. Dynamic interactions of a transcription factor with DNA are accelerated by a chromatin remodeler.  EMBO Reports. 5: 1064-1070, 2004
 +
Tatiana S. Karpova, Min J. Kim, Corentin Spriet,  Kip Nalley,  Tim Stasevich, Zoulika Kherrouche, Laurent Heliot, and James G. McNally. Concurrent Fast and Slow Cycling of a Transcriptional Activator at an Endogenous Promoter. Science 319: 466-469, 2008
 +
Applicants should contact Dr. Tatiana Karpova (karpovat@mail.nih.gov) and submit their CV.

Revision as of 16:59, 15 April 2014

Postdoctoral position in Cell Biology, Univ. of Miami, Florida (posted April 2014)

A Postdoctoral position is available in the lab of Dr. Sandra Lemmon, University of Miami, Miller School of Medicine. Research focuses on regulation of membrane dynamics in the yeast S. cerevisiae. Particular interests include the role of phosphorylation, the actin cytoskeleton, and lipids in endocytosis and the function of clathrin in endocytosis and sorting to the lysosome/vacuole. For information on research interests check: <http://biomed.miami.edu/?p=482&pid=208&m=facultyph&mid=0&item=9>.

Qualifications: Candidates should have a PhD in chemistry, biology, genetics or a related life science. Applicants with a background in cell biology, yeast genetics and molecular biology, fluorescence microscopy and/or lipid biochemistry are especially encouraged to apply. Please submit a curriculum vitae, publications, summary of past research experiences, research interests, and the names of three references to: Dr. Sandra Lemmon at <slemmon[at]miami[dot]edu>.


Postdoctoral Fellowship in yeast evolutionary genomics at Stanford University

The Fraser Lab in the Department of Biology is seeking a postdoctoral fellow to work on the evolution of gene expression in Saccharomyces yeast. The exact subject is flexible, but will likely involve using RNA-seq to answer fundamental questions about the mechanisms and consequences of gene expression evolution- especially in cases of evolutionary adaptations. The ideal candidate would have experience in yeast molecular biology techniques, as well as some familiarity with computational and/or evolutionary analysis. Salary and benefits are both above the NIH standards for postdocs. Please email a cover letter and CV to hbfraser[at]stanford[dot]edu.

Research Associate position (Ph.D. level) at Stanford University

The Fraser Lab in the Department of Biology is seeking a Basic Life Science Research Associate (Ph.D. level). We apply the exciting tools of genomics and high-throughput sequencing to study the evolution of gene expression in a variety of species, but primarily budding yeast. Duties will include:

• Performing a wide range of experiments with the yeast S. cerevisiae. These will focus on a revolutionary new tool in molecular biology: genetic engineering via the CRISPR/Cas system. Other experiments will include gene knockout/replacement, chromatin immunoprecipitation, and high-throughput sequencing of mRNA. • Teaching experimental protocols to others in the lab • Keeping the lab's yeast strains/chemicals organized • Overseeing an undergraduate student for dishwashing/media preparation

A Ph.D. in a Biology-related field is required, with at least 2 years spent working with S. cerevisiae. Also desirable (but not required) is experience with: mammalian cell culture, chromatin immunoprecipitation, and/or high-throughput sequencing. Please email a cover letter and CV to hbfraser[at]stanford[dot]edu.


Postdoctoral fellowship in cell cycle evolution at the Institute of Genetics and Development of Rennes, France

A three-year post-doctoral position supported by a starting grant from the European Research Council (ERC) is available in the group of Dr. Damien Coudreuse at the Institute of Genetics and Development of Rennes (IGDR), France (http://igdr.univ-rennes1.fr/english/). Research in this laboratory takes a synthetic biology approach in fission yeast to study the architecture and evolution of cell cycle regulation. The proposed project aims at understanding fundamental aspects of the evolution of cell proliferation, from how cells overcome external challenges to common features of independent evolutionary processes. It will be based on the use of fission yeast cells operating with various minimal cell cycle control circuits as starting points for experimental evolution approaches. Candidates should contact Dr. Damien Coudreuse at damien.coudreuse@univ-rennes1.fr and send a Curriculum Vitae, including past research experiences and publication records, as well as a letter detailing their motivation and interest in our work. Applicants should also request recommendation letters to be directly sent by two or three references.


Postdoctoral Fellowship in Cell Fate and Gene Regulation (POS00123), LRI/Crick Institute, London, UK

We seek a talented and motivated Postdoc to join the Cell Fate and Gene Regulation Laboratory in London, UK. The Cell Fate and Gene Regulation laboratory headed by Dr Folkert van Werven will be opened in the fall of this year. It will be a small, highly interactive, international research group that focuses on understanding the molecular mechanisms of how cell fate decisions are controlled. Initially we will use budding yeast as a model system, and take molecular, systematic and quantitative approaches (including single-molecule, proteomic, and genomic techniques) to study this problem. For more information please send an email (Folkert.vanWerven at cancer.org.uk) or go to: https://cruk.taleo.net/careersection/cruk_corporate/jobdetail.ftl?lang=en&job=POS00123&view=rss


Postdoctoral Position in Biology of Yeast Colonies at Charles University in Prague, Czech Republic

Postdoctoral positions are available in the lab of Zdena Palkova (http://www.natur.cuni.cz/~zdenap). The Research Group is interested in different aspects of yeast multicellularity including questions related to topics of yeast cell differentiation, ageing, stress defense, adaptation and longevity that are crucial in any organism, including humans.

Selected recent references: • Cap M, Stepanek L, Harant K, Vachova L, Palkova Z. (2012) Cell differentiation within a yeast colony: metabolic and regulatory parallels with a tumor-affected organism. Mol Cell 46: 436-448 • Vachova L, Stovicek V, Hlavacek O, Chernyavskiy O, Stepanek L, Kubinová L, Palkova Z. (2011) Flo11p, drug efflux pumps, and the extracellular matrix cooperate to form biofilm yeast colonies. J Cell Biol. 194: 679-87.

Candidates should have experience in molecular and cellular biology and methodical knowledge in techniques of yeast cell growth and manipulation. In addition, candidates should have high motivation and ability to work independently and take responsibility for his/her own project as well as to work in a team.

The applicants should have (i) a recent PhD (the degree obtained no earlier than on 28th of March 2008), (ii) promising publication record and be able to speak fluent English (or Czech). Please send your motivation letter (<500 words), CV, list of publications (including IF and the number of citations) and contact information of three references directly to the group leader Zdena Palkova, mailto:zdenap@natur.cuni.cz (please combine all documents into single PDF file). Applications will be considered until suitable candidates are found. The positions include additional funds for the international mobility (3 months).


PhD student in Molecular Biology (Marie Curie Early Stage Researcher)at the University of Gothenburg, Sweden

A PhD student position in Molecular Biology/Systems Biology is available in the lab of Prof. Stefan Hohmann, Dept of Cell and Molecular Biology, University of Gothenburg, Sweden.

The research project “Experimental investigation of the yeast Hxk2/Snf1/Mig1 network” aims to understand the dynamic control of the Hxk2/Snf1/Mig1 glucose signalling pathway employing single cell technology developed in the ISOLATE project. Here the experimental platform generated in the project will be optimized, especially the formation of cell arrays of synchronized cells as well as image analysis. Using in parallel Mig1 and Msn2 reporters, response thresholds under different glucose levels will be establish and effects on cell-to-cell variability and bistability will be determined.

Requested Background(advantageous but not required): Yeast biology, yeast genetics, glucose signalling, use of microfluidic devices, microscopy, image analysis, application of nano-sensor technology, ‘systems’ thinking.

The Marie Curie project ISOLATE is a collaborative research and training network between eight partners, incl. in different European countries. The PhD students and postdocs in the project will perform top-notch research and will additionally benefit from an excellent training network offered by the project partners. Research stays during the PhD projects in other partners’ labs are strongly encouraged. Primarily recruitment of researchers from EC Member States and associated countries, but also open to researchers from third countries. Researchers are normally required to move from one country to another when taking up the appointment.

Please send an application including (1) a max. one-page cover letter containing a justification why this position was chosen as well as a career vision statement, (2) a complete CV with details on education, previous research activities and a list of publications (if any,)(3) a copy of the passport or ID with picture, (4) two letters of recommendation, to maria.enge@gu.se (Project Manager in Prof. Hohmann's group).

PhD student in Systems Biology (Marie Curie Early Stage Researcher)at the University of Gothenburg, Sweden

A PhD student position in Systems Biology is available in the lab of Prof. Stefan Hohmann, Dept of Cell and Molecular Biology, University of Gothenburg, Sweden.

The research project “Theoretical investigation of the yeast Hxk2/Snf1/Mig1 network” aims to understand the dynamic control of the Hxk2/Snf1/Mig1 glucose signalling pathway employing single cell technology developed in the ISOLATE project. Data generated in the project will be interpreted by mathematical modelling together with other project partners to understand feedback and feed-forward mechanisms of signalling. Mutants and inhibitory compounds will be used to test how those affect thresholds and bistability. The analysis will reveal the genetic determination of the system properties, how they are regulated and how robustness against perturbation is established.

Requested Background(advantageous but not required): Yeast biology, yeast genetics, glucose signaling, microscopy, image analysis, development of mathematical models, ‘systems’ thinking.

The Marie Curie project ISOLATE is a collaborative research and training network between eight partners, incl. in different European countries. The PhD students and postdocs in the project will perform top-notch research and will additionally benefit from an excellent training network offered by the project partners. Research stays during the PhD projects in other partners’ labs are strongly encouraged. Primarily recruitment of researchers from EC Member States and associated countries, but also open to researchers from third countries. Researchers are normally required to move from one country to another when taking up the appointment.

Please send an application including (1) a max. one-page cover letter containing a justification why this position was chosen as well as a career vision statement, (2) a complete CV with details on education, previous research activities and a list of publications (if any,)(3) a copy of the passport or ID with picture, (4) two letters of recommendation, to maria.enge@gu.se (Project Manager in Prof. Hohmann's group).

Postdoctoral position to study Ty1 retrotransposition at the University of Georgia

A postdoctoral position is available in the lab of David J. Garfinkel, Department of Biochemistry and Molecular Biology, University of Georgia, Athens GA to work on the retrovirus-like transposon Ty1 of Saccharomyces. Specifically, we are investigating a new form of RNA-interference based on Ty1 antisense RNAs that acts posttranslationally and targets Ty1 proteins in the absence of the conserved RNAi pathways.

Experience in molecular genetics, protein/nucleic acid interactions or cytology would be helpful.

Also see our website for further information [1]

Please send resume or inquiries to:

David J. Garfinkel
Department of Biochemistry and Molecular Biology
A130 Life Sciences
120 Green St.
University of Georgia
Athens, GA 30622

tel: 706-542-9403
djgarf@bmb.uga.edu

Yeast Systems Biology Position at Virginia Tech (Research Associate or Sr Research Associate)

The Synthetic Biology group at Virginia Bioinformatics Institute (VBI) is involved in two collaborative research projects focused on the development of mathematical models of gene-protein regulatory networks controlling cell growth and division. Temporal organization of the budding yeast cell cycle has been studied from two vantage points: bottom-up models emphasize a protein regulatory network centered around cyclin-dependent protein kinases, whereas top-down models focus on a gene regulatory network governed by interrelated transcription factors. The first project is focused on unifying these two perspectives. The second project is focused on the development of stochastic models of the regulatory network controlling the cell cycle. Both projects are performed in close collaboration with experts in computer science, data mining, bioinformatics, and mathematical modeling. The successful candidate will be expected to contribute significantly to these two projects by being responsible for designing and performing experiments used to validate model predictions. These experiments will involve the development of a new collection of cell cycle mutants and their quantitative characterization by time-lapse microscopy. In addition, the successful candidate will be expected to prepare the results for publication and presentation, to help supervise graduate and undergraduate students, and to contribute to grant proposals.

Dependent on the qualifications of the successful candidate, the position will hold the research faculty rank of either Research Associate or Senior Research Associate.

Go to the position description for additional information and for submitting applications.

More information about our team can be found by visiting:

Postdoctoral position - Laboratory of Cell Physics - Strasbourg, France

Postdoctoral position is available in the Laboratory of Cell Physics, ISIS/IGBMC, Strasbourg, France. The project will focus on the dynamics of the cytokinetic ring in the fission yeast S. pombe. The roles of the Rho GTPase, actin polymerisation, and myosin will be studied. The work will involve genetics, cell biology, microscopy, microfabrication and microfluidics; for more information, send a CV and contact information of referees to Dr. Daniel Riveline (riveline@unistra.fr)

Postdoctoral Position in Quantitative Systems Biology

A postdoctoral fellow position is immediately available for a highly motivated recent PhD or MD/PhD graduate in biomedical science in the lab of Dr. Gregor Neuert at Vanderbilt University School of Medicine in Nashville, Tennessee.

The main interests of the group focuses on quantitative understanding of signaling and gene regulatory processes of coding and non-coding RNA in single cells at single molecule resolution. Our research methods include a combination of single-cell experimental and computational techniques as well as molecular biology and yeast genetics.

We are seeking highly motivated and curious applicants with strong background in yeast genetics, molecular biology and computational biology. Background in microscopy and computational modeling is also considered a plus but not required.

We offer a highly interactive, international and interdisciplinary research environment with strong mentoring and career development support. Vanderbilt University School of Medicine is ranked #9 in NIH funding and #15 in U.S. News medical school ranking and is equipped with world-class cutting-edge core facilities.

Selected publications: Neuert, Munsky et al. Science 2013 ; Munsky, Neuert et al. Science 2012; Bumgarner, Neuert et al. Mol.Cell 2012; Van Werven, Neuert et al. Cell 2013

Interested applicants should send curriculum vitae, a summary of research experience and accomplishments, and contact information of 2-3 references to gregor.neuert@vanderbilt.edu.

For more information please visit: https://www.mc.vanderbilt.edu/root/vumc.php?site=neuertlab


POSTDOCTORAL POSITION - NIH, National Cancer Institute, Posted April 16, 2014

A postdoctoral position is available within the Optical Imaging Core of the Laboratory of Receptor Biology and Gene Expression (NCI/NIH) to conduct research in the regulation of transcription in Saccharomyces cerevisiae. The candidate is expected to have a background in yeast genetics and molecular biology and to be interested in extensive live imaging by fluorescence microscopy and in super-resolution methods. Publications in the area of research: Tatiana S. Karpova, Teresa Y. Chen, Brian L. Sprague, James G. McNally. Dynamic interactions of a transcription factor with DNA are accelerated by a chromatin remodeler. EMBO Reports. 5: 1064-1070, 2004 Tatiana S. Karpova, Min J. Kim, Corentin Spriet, Kip Nalley, Tim Stasevich, Zoulika Kherrouche, Laurent Heliot, and James G. McNally. Concurrent Fast and Slow Cycling of a Transcriptional Activator at an Endogenous Promoter. Science 319: 466-469, 2008 Applicants should contact Dr. Tatiana Karpova (karpovat@mail.nih.gov) and submit their CV.